Fueling innovation in the premium dental market Francisco Faoro Head Product Development BUSurgical 8 October 2012
Straumann a global leader in replacement, restorative and regenerative dentistry A pioneer of dental implants Founded as a family owned research institute in 1954 Headquartered in Basel, Switzerland Dental solutions available in more than 70 countries through 20 fully owned sales subsidiaries and a broad distributor network >2400 employees from 30+ nations Straumann 2
Half a century of science-based innovation and precision engineering 1954 1970 Material testing and research 1970 1990 Medical devices Since 1990 Dental medical devices 1974 First Straumann Dental implant Straumann 3
A global business Andover (USA): Implant production Malmö (S): Regenerative products Leipzig (D): CADCAM milling Gräfelfing (D): scanner assembly Villeret (CH): Implant production Arlington (USA): CADCAM milling Straumann subsidiaries Production plants Distributors Head Quarter Present in >70 countries through 20 sales subsidiaries and a broad distributor network Straumann 4
has achieved leadership through organic growth and innovation Drivers Growth Straumann Geographical Expanding provider base Tooth replacement, restoration and regeneration Straumann Innovation Solution and service Global GDP Straumann 5
What drives the choice to buy premium products? Factors influencing customer choice of implant company 1 6% Proportion of respondents 2 willing to pay a premium for indicated product features 100 18% 80 60 % 48% 40 20 28% 0 New surface New material Prevention of peri-implantitis Optimal size Service & practice support Education Pricing Innovation & product performance New surface scored highest in the US New surface and new material ranked top in Europe Prevention of peri-implantitis scored best in Asia Straumann 6 1 Perception pulse study: dental implants 2011; 2046 respondents in Americas, Asia, and Europe, MRG 2 SAi MedPartners 2011 Sample: 170 respondents in Americas, Asia, and Europe
Innovation leadership based on surface- and material science Innovation 2011 NNC Small diameter implants with wider indication 2009 Roxolid Enhanced mechanical properties 2005 SLActive Superior osseointegration 1994 SLA Enhanced osseointegration 1974 TPS Better osseointegration 400b.c. metal straps (Etruscan) 600a.c. ivory teeth (Honduras) 1960 Invasive implants in lower jaw 1970 Blade implants Time Straumann Straumann 7 Market
Straumann leads implant surface innovation 1974 1994 2005 1st generation 2nd generation 3rd generation TPS Macro Development of surface topography Straumann SLActive SLActive SLA Micro Molecular Development of surface chemistry 8
Hydrophilic surface cuts healing time in half 1 Body has to remove the passive layer for osseointegration Body can immediately access the active surface for osseointegration Hydrophobic sand blasted and acid etched titanium surface 2 Hydrophilic sand blasted and acid etched titanium surface 3 1 Raghavendra, Wood, Taylor, 2005 and Oates et al., 2007 Straumann 2 Straumann SLA 9 3 Straumann SLActive
Bone remodelling with SLActive also in large defects New bone Surrounding bone SLA Implant SLActive Implant Surrounding bone Histological cross-sections at 12 weeks after implant placement Straumann Results from preclinical studies presented by Becker J, Schwarz F (Heinrich-Heine University, 10 Düsseldorf, Germany) at 15th Ann. Sci. Meeting of the EAO, Zürich, 2006
There is an increasing trend towards narrow implants which is based on Clinical needs: - small bone ridge - small inter-dental gap - bone conservation Straumann With courtesy of Dr Roccuzzo, Italy Patient requirements: - less invasive treatment - reduced treatment time - less cost intensive - aesthetic solution 11
Roxolid designed for more confidence by combining strength and excellent osseointegration 1500 Tensile Streght [Mpa] 1000 500 0 ASTM TiGr4 1) STMN TiGr4 2) Roxolid 3) Higher strength than pure titanium 1,2,3 Higher stability 1,2,3 More bone in-growth 4 Improved osseointegration 4 Roxolid Implant Surrounding bone Straumann 1 ASTM F67 2 used for all Ti Straumann implants 3 used for all Roxolid Straumann implants 4 Gottlow, J., et al. "Evaluation of a New Titanium-Zirconium Dental Implant: A Biomechanical and Histological Comparative Study in the Mini Pig." Clin.Implant.Dent.Relat Res. (2010). 12
The usage of narrow implants is currently limited to front teeth Straumann 13
Narrow implants have limited treatment options 400 Fatigue strength [N] 350 300 250 200 150 100 Enhanced material Current material Benchmark for molar region 1 Benchmark for pre-molar region 1 Benchmark for anterior region 1 50 0 0 1 2 3 4 5 6 Ø Implant [mm] Strong correlation between implant diameter and its fatigue stregth 2 1 2012-09-05 Mech Strength Benchmarking for Dent Impl Syst_V02 (Straumann internal data) Straumann 2 14 According to ISO 14801; data on file (Straumann)
To maintain leadership in innovation leapfrogging technology in materials is needed 1400 1200 1000 Tensile Strength [MPa] 800 600 400? 200 0 ASTM TiGr4 Straumann TiGr4 Roxolid Enhanced material Straumann 15
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