Controversies in Gastrointestinal Tumor Therapy

Controversies in Gastrointestinal Tumor Therapy

Frontiers of Radiation Therapy and Oncology Vol. 38 Series Editors J.L. Meyer San Francisco, Calif. W. Hinkelbein Berlin

6th International Symposium on Special Aspects of Radiotherapy, Berlin, September 5 7, 2002 Controversies in Gastrointestinal Tumor Therapy Volume Editors T. Wiegel Berlin S. Höcht Berlin M. Sternemann Berlin H.J. Buhr Berlin W. Hinkelbein Berlin 43 figures, 6 in color, and 10 tables, 2004 Basel Freiburg Paris London New York Bangalore Bangkok Singapore Tokyo Sydney

Frontiers of Radiation Therapy and Oncology Founded 1968 by J.M. Vaeth, San Francisco, Calif. Prof. Dr.T.Wiegel Charité Campus Benjamin Franklin Department of Radiology Berlin (Germany) Library of Congress Cataloging-in-Publication Data International Symposium on Special Aspects of Radiotherapy (6th : 2002: Berlin, Germany) Controversies in gastrointestinal tumor therapy / 6th International Symposium on Special Aspects of Radiotherapy, Berlin, September 5 7, 2002; vol. editors, T. Wiegel [et al.]. p.: cm. (Frontiers of radiation therapy and oncology, ISSN 0071 9676 ; v. 38) Includes bibliographical references and index. ISBN 3 8055 7690 0 1. Rectum Cancer Radiotherapy Congresses. 2. Pancreas Cancer Radiotherapy Congresses. 3. Liver metastasis Radiotherapy Congresses. I. Wiegel, T. II. Title. III. Series. RC280.R37I55 2002 616.99 4330642 dc22 2004043473 Bibliographic Indices. This publication is listed in bibliographic services, including Current Contents and Index Medicus. Drug Dosage. The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Copyright 2004 by S. Karger AG, P.O. Box, CH 4009 Basel (Switzerland) www.karger.com Printed in Switzerland on acid-free paper by Reinhardt Druck, Basel ISSN 0071 9676 ISBN 3 8055 7690 0

Contents Diagnostics and Therapy of Rectal Carcinoma 1 Magnetic Resonance Imaging of Rectal Cancer:What Radiation Oncologists Need to Know Beets-Tan, R.G.H.; Vliegen, R.F.A.; Beets, G.L. (Maastricht) 13 Neoadjuvant Radiochemotherapy in Rectal Cancer: For Which Patients and Tumor Stages? Rödel, C.; Sauer, R. (Erlangen) 24 Overview of the Role of Preoperative Radiotherapy to Increase Sphincter Preservation for Rectal Cancer Gerard, J.-P. (Nice); Romestaing, P.; Chapet, O. (Pierre Bénite); Baulieux, J. (Lyon) 28 Surgery Alone: Is Total Mesorectal Excision Sufficient for Rectal Cancer? Daniels, I.R.; Moran, B.J.; Heald, R.J. (Basingstoke) 37 Recurrent Rectal Cancer: How to Predict Resectability? Vogl, T.J.; Pegios, W. (Frankfurt am Main) 41 A Multicenter Analysis of 123 Patients with Recurrent Rectal Cancer within the Pelvis Höcht, S.; Hammad, R. (Berlin); Thiel, H. (Bamberg); Wiegel, T.; Siegmann, A. (Berlin); Willner, J. (Würzburg); Wust, P. (Berlin); Herrmann, T. (Dresden); Eble, M. (Aachen); Carstens, D. (Hamburg); Flentje, M. (Würzburg); Neumann, P.; Hinkelbein, W. (Berlin) V

52 Intraoperative Radiotherapy Special Focus: Recurrent Rectal Carcinoma Treiber, M.; Lehnert, T.; Oertel, S.; Krempien, R.; Bischof, M.; Buechler, M.; Wannenmacher, M.; Debus, J. (Heidelberg) 57 Local Recurrence of Rectal Carcinoma: Radio-Oncologic Strategies Lukas, P.H. (Innsbruck) Diagnostics and Therapy of Pancreatic Carcinoma 67 Diagnostic Imaging of Pancreatic Cancer The Role of PET Zimny, M. (Aachen) 76 Adjuvant Radiochemotherapy in Pancreatic Cancer: Contra Henne-Bruns, D.; Staib, L. (Ulm) 82 Adjuvant Radiochemotherapy for Pancreatic Cancer Why We Might Need It Even More Fleckenstein, J.; Rübe, C. (Homburg) 87 Radiochemotherapy in Unresectable Pancreatic Cancer Höcht, S.; Wiegel, T.; Siegmann, A.; Hinkelbein, W. (Berlin) Treatment of Liver Metastases 94 Surgical Resection of Colorectal Metastases Jonas, S.; Thelen, A.; Benckert, C.; Neuhaus, P. (Berlin) 100 Stereotactic Radiation Therapy of Liver Metastases: Update of the Initial Phase-I/II Trial Herfarth, K.K.; Debus, J.; Wannenmacher, M. (Heidelberg) 106 Laser-Induced Thermotherapy of Liver Metastases Ritz, J.-P.; Isbert, C.; Roggan, A.; Buhr, H.J.; Germer, C.-T. (Berlin) 122 Author Index 123 Subject Index Contents VI