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CURRICULUM VITAE PERSONAL DETAILS Name: Dr. Hellen Nyambura Kariuki Office: Department of Medical Physiology, School of Medicine, College of Health Sciences, University of Nairobi, Chiromo Campus Address: P.O. Box 30197 (00100), Nairobi Private: P.O. Box 7787(00300), Nairobi Telephone: 254 020 4442309 Telephone: Mobile : 254 722 605 587 E-mail hellen.kariuki@uonbi.ac.ke hnkariuki@yahoo.com ACADEMIC QUALIFICATIONS University Education 2007 to date PhD Medical Physiology. At thesis writing stage 1996 Master of Science in Medical Physiology, University of Nairobi 1989 Bachelor of Dental Surgery, University of Nairobi OTHER PROFFESIONAL QUALIFICATIONS Registered with Kenya Medical Practitioners and Dentists Board Secondary Education:- 1982 1983: Kenya Advanced Certificate of Education, Limuru Girls School 1978 1981: Kenya Certificate of Education, Limuru Girls School APPOINTMENTS 2001 - to date: Lecturer, Dept. of Medical Physiology, University of Nairobi. Teaching both the undergraduate and postgraduate students. 1996-2001: Assistant lecturer, Dept. of Medical Physiology, University of Nairobi. 1991-1996: Tutorial Fellow, Dept. of Medical Physiology, University of Nairobi. 1990-1991: Dental Officer - Provincial General Hospital, Nyeri. 1989-1990: Dental Intern Kenyatta National Hospital. D 1

WORK EXPERIENCE - RESPONSIBILITIES AND POSITIONS HELD 2010 Secretary to the departmental Curriculum review Committee 2008 to date International Association for the Study of Pain (IASP) Education Initiative Working Group 2007-2009: Secretary to the departmental Research, Development and Collaboration Committee 2006- to date: Departmental procurement committee and departmental curriculum committee 2005-2006: Secretary pre-clinical income generating activities committee 2007: Secretary faculty Dress Code Committee. 2006-to date: of School of Medicine, Pharmacy Dental Sciences and Nursing academic boards 2006: Department liaison person on collaborations 2000- to 2005: Departmental Schedules Mistress. 2005: of the Faculty of Medicine curriculum review committee. 1998-2004: Departmental representative to the Faculty of Dental Sciences. 1996-1997: Curriculum Committee Faculty of Pharmacy 1997: Faculty of pharmacy curriculum review editorial board member. 1996: Departmental representative to the faculty of pharmacy board of examiners 1996 Departmental representative to the faculty of pharmacy curriculum review committee. PUBLICATIONS 2011 The Antinociceptive Antipyretic Effects of Solanum incanum (Linneaus) in Animal Models Mwonjoria J. K, Kariuki H N, and Waweru FN. International Journal of Phytopharmacology. 2011, 2(1), 22-26. 2011 National Palliative Care Training Manual. As a contributor and editor. (Manual submitted to the MoH for launch) 2010 Antinociceptive and Antinflammatory Effects of Toddalia asaitica Root Extract in Swiss Albino Mice. Hellen N. Kariuki, Titus I.Kanui, Nilesh B. Patel, Abiy Yenesew. (Manuscript in preparation) 2010 Knowledge, Attitude and Practice of Clinical Officers to Pain and Pain Management in Kenya. Hellen N. Kariuki and Zipporah Ali (Manuscript in preparation) 2010 Patients Attitude Towards Pain and Pain Management in Kenya. Kopf A.,

Kariuki H., Patel N. (Manuscript in preparation). 1998 H. N. Kariuki: Analgesic Effects of Clomipramine and Carbamazapine in combination with Pethidine using the formalin test. MSc Thesis University of Nairobi, 1998. 1997 R.W. Kahama, D.N. Kariuki, H. N. Kariuki and L.W. Njenga: Flourosis in Children and sources of Fluoride around Lake Elementaita region of Kenya. Fluoride 30 (1) 19-25,1997 1997 N. M. Ngakinya, B. N. Ngotho, H. N. Kariuki, J.T. Kaimenyi and F.L. Ndungu. Periodontal Health status of patients attending Diabetic clinic at Kenyatta National Hospital. Indian Journal of Dental Research 8 (4) 105-110, 1997. GRANTS RECIEVED 2010 IASP developing countries education grant for training palliative care nursing staff in mission hospitals in the rural areas of Kenya on pain and pain management. 2008 IASP developing countries education grant for training healthcare professionals on pain and pain management. 2008 University of Nairobi Deans Committee. To carry out a study on the Antinociceptive effects of ten medicinal plants using animal models. 1996 University of Nairobi Deans Committee. To carry out a study on Analgesic Effects of Clomipramine and Carbamazapine in combination with Pethidine using the formalin test. WORKSHOPS / SEMINARS / CONFERENCES ATTENDED 2011 Palliative Care: An Essential Part of Medical and Nursing Training. From an Education Conference in Oct. 2008 to Action. Nairobi, Kenya 2010 Palliative Care in Cancer, Salzburg,Austria 2010 2 nd KEHPCA conference in Nairobi, Kenya. 2010 3 rd APCA conference in Windhoek Namimbia 2010 Transformational Leadership facilitators Training, Nairobi 2010 18 th Kenya Society of Anaesthesiologist Annual scientific Conference, Mombasa 2010 CME- A Relook at the Use of Morphine in Clinical Medicine, Nairobi 2010 Proposal writing for European Union grants workshop, Nairobi 2010 Palliative Care Curriculum Review (As a Curriculum consultant), Nairobi 2010 IASP Pain Education Initiative Working Group Meeting, London 2010 Palliative Care Curriculum for Medical Training Institutions review Workshop, Nairobi 2010 Africa Palliative Care Association (APCA) ToT course on use of Opioids in Pain Management, Kampala 2010 Scientific Communication and Publishing, Nairobi, Kenya D 3

2010 Palliative Care Initiative Research meeting Nairobi, Kenya 2010 Transforming Leadership Seminar III (Facilitator) Nairobi, Kenya 2009 APCA country progress workshop, Kampala 2009 4 th All Africa Anesthesia Congress. Nairobi, Kenya 2009 ELNEC- Palliative care education, Nairobi, Kenya 2009 Transforming Leadership Seminar II (Facilitator) Nairobi, Kenya 2009 Cineca Biodata for Communicable Diseases. Nairobi, Kenya 2009 Clinical Officers annual Scientific Conference. Mombasa, Kenya 2009 Opioid availability workshop. Nairobi, Kenya 2009 Transforming Leadership Seminar I. Nairobi, Kenya 2009 Training in Pedagogy for university academic staff Nairobi, Kenya 2008 Neuroscience school: Behavioral sciences Nairobi, Kenya 2008 1 st KEHPCA Palliative Care Conference, Nairobi Kenya 2008 12 th World Congress on Pain, Glasgow, Scotland 2008 Kenya Society for Pain: Pain Symposium in Nairobi 2008 5th African Association of Physiological Sciences Congress in Nairobi, Kenya 2008 Physiology teaching workshop organized by ADinstruments. Nairobi, Kenya 2008 International Conference of Comparative Physiology and Biochemistry-MARA 2008. Kenya 2008 Opioid availability task force workshop Nairobi, Kenya 2008 Curriculum committee - Harmonization of pre-clinical teaching workshop editorial Nairobi, Kenya 2008 Curriculum committee - Harmonization of pre-clinical teaching workshop Nairobi, Kenya 2007 Good Laboratory Practice workshop organized by WHO Nairobi, Kenya 2007: Opioid Availability workshop organized by KEPHA Nairobi, Kenya 2007: ADinsruments training held in the Department of Medical Physioogy, Nairobi, Kenya 2006: Neuroscience school; Channels to circuits. In cape Town South Africa 2006: ISO 2600: Social Responsibility workshop organized by Kenya National Commission on Human Rights Nairobi, Kenya 2006: Laboratory Animal Science course. Nairobi, Kenya 2006: Pain workshop on opioid availability Nairobi, Kenya

2005: Pain workshop organized by IASP. Nairobi, Kenya 2004 2006 Kenya Physiological Society monthly seminars. Nairobi, Kenya 2003 First Ladies International Conference on HIV and AIDS 2002. Kenya Society of Neuroscience: symposium Nairobi, Kenya 2002 of Departmental committee on HIV 2001 Workshop on Professional skills for Scientists sponsored by Society of Neuroscientists of Africa. Nairobi, Kenya 2001: Society of Neuroscientists of Africa Conference. Nairobi, Kenya 1997: Kenya Society for Epilepsy symposium held in Nairobi, Kenya 1996: Neuroscience lecture course on neurotransmitters and their receptors at Rhodes University, Grahamstown, South Africa. 1993: Society of Neuroscientists of Africa Conference, Nairobi, Kenya 1992: African Association of Physiological Societies Conferences, Nairobi, Kenya. 1998 to date Attended all seminars and conferences organized by Kenya Dental Association PRESENTATIONS Poster Presentations 2010 The Antinociceptive Effects of Toddalia asiatica Bark Extract using Hot Plate and Tail Flick Tests on Mice. 13 th world Congress on Pain. 2009 Patients Attitudes towards pain and pain treatment in Kenya. Kariuki H. N, Kopf A., Patel N. B., Rajput M. N. British Pain Society annual conference 2009 Patients Attitudes towards pain and pain treatment in Kenya. Kariuki H. N, Kopf A., Patel N. B., Rajput M. N. 5th World Congress of the World Institute of Pain, Accepted but not presented 2008 Antinociceptive effects of Toddalia asiatica in writhing and formalin tests using mice. 12th World Congress on Pain, Glasgow, Scotland. Poster presentation 2008 Antinociceptive effects of Rhus natalensis in the tail flick and formalin tests using mice. International Conference of Comparative Physiology and Biochemistry-MARA 2008 Kenya. Poster presentation 2008 H. N. Kariuki, T. I. Kanui and P. G. Kioy: The analgesic effects of clomipramine individually and in combination with pethidine using the formalin test. 7th International Symposium: The Pain Clinic. October 2-6, 1996, Istanbul Turkey. Poster presentation. 1996 H. N. Kariuki, T. I. Kanui and P. G. Kioy: The analgesic effects of clomipramine individually and in combination with pethidine using the D 5

formalin test. 7th International Symposium: The Pain Clinic. October 2-6, 1996, Istanbul Turkey. Poster presentation. Oral Presentations 2010 Teaching Pain and Pain management in Kenya. 1st pain Teaching Conference, Toronto, Canada. 2010 Knowledge, Attitude and Practice of clinical officers to Pain and Pain Management in Kenya. 2 nd KEHPCA Palliative Care Conference, Nairobi, Kenya 2010 Pathophysiology of pain: Pain Symposium at the 18 th Kenya Society of Anaesthesiologist Annual scientific Conference, Mombasa 2010 Benefits of Good Pain Management: Pain Symposium at the 18 th Kenya Society of Anaesthesiologist Annual scientific Conference, Mombasa 2010 Training Medical doctors on opioids in pain management, Nairobi 2010 ToT Training for Medical institutions tutors as a trainer, Nairobi 2010 Pathophysiology of Pain: Introductory Palliative Care Course in KNH. 2010 Pathophysiology of Pain: Introductory Palliative Care Course to the Nursing Council of Kenya. 2010 Pathophysiology of Pain: Introductory Palliative Care Course in KNH. 2009 Palliative Care in Kenya- The Challenges: Clinical Officers annual Scientific Conference 2009 Patients attitude towards pain and pain treatment in Kenya: 1st KEHPCA palliative Care conference; Nairobi Kenya. Oral presentation 2008 Attitudes and practice of healthcare professional in Pain Management in Kenya: Pain Symposium: 5 th Africa Association of Physiological Sciences Nairobi, Kenya. Oral presentation 2008 Income Generating Activities of the Department of Medical physiology. College of Biological and Physical Sciences workshop. Oral presentation 2006 The physiology of the spinal cord. A Norvatis sponsored CME. Oral presentation 2006 The physiology of the spinal cord. A Norvatis sponsored CME. Oral presentation WORK IN PROGRESS 1 Antinociceptive Activities of some Medicinal Plant Extracts using Animal Models; PhD project at data analysis and thesis writing stage 2 Outcomes of ART patients receiving palliative care: randomized controlled trial evaluations in 2 sub-saharan African countries. As Co-investigator in collaboration with Kings College London. As the Kenyan academic leader. 3 The analgesic effects of non steroidal anti-inflammatory drugs on subcutaneous formalin model of pain in mice. 4 Evaluation of pain prevalence and treatment quality in Kenya

RESEARCH SUPERVISION MSc. Medical Physiology 2010 Charles Besley (Cardiff University (UK)) 2009 John K. Mwonjoria (University of Nairobi, Kenya) A Pilot Study Investigating the Effect of a Patient Held Pain Assessment Tool in Palliative Care Outpatients at AIC Kijabe Hospital. A Quantitative Experimental Study with Pre- & Post-Intervention Comparison (Project at commencement stage) Antinociceptive & anti-inflammatory effects of Solanium incunum root extract in animal models (Thesis submitted) BSc. Intercalated 2008 Edwin Barasa Wabwire Antinociceptive activity of Solanium incunum root extract in animal models of pain 2007: Eric Mbugua Thuo Antinociceptive activity of Toddalia asiatica root extract in animal models of pain 2007: Felix Oindi Antinociceptive effects of Toddalia asiatica leaf extract in animal models of pain 2005: Hellen Cherono Analgesic activities of Catha edulis extract using the formalin test. MSc. Thesis Examination 2011 John K. Mwonjoria (UoN) As an internal examiner. 2006 Githinji Charles Githua (UoN) As an internal examiner. Antinociceptive & anti-inflammatory effects of Solanium incunum root extract in animal models Effects of Mondia whytei aqueous root on isolated rabbit heart and jejunum preparation. MEMBERSHIP TO PROFESSIONAL ORGANISATIONS Organization Position held Kenya Society for Pain Secretary General International Association for the Study of Pain IASP Education Initiative Working Group International association of Hospices and Palliative Care Opioid Availability Task Force Registered member D 7

Kenya physiological Society Kenya Dental Association. International Brain Research Alumni Kenya Hospices and Palliative Care Association Vice- Chair OTHERS Directors Metropolitan hospital of the Nairobi Baptist Church of the Board of Protecting Life Movement of the Board of Crisis Pregnancy Ministries Committee member of Nairobi Baptist Outreach through Welfare REFEREES: Prof. Titus. I. Kanui Dept. of Animal Physiology University of Nairobi P.O. Box 30197 (00100) Tel. +254 722448952 Nairobi, Kenya e-mail: tkanui@uonbi.ac.ke Prof. Paul. G. Kioy Dept. of Medical Physiology University of Nairobi P.O. Box 30197 (00100) Tel. +254 722792010 Nairobi, Kenya e-mail: pgkioy@uhmc.co.ke Prof. Nilesh B. Patel, Dept. of Medical Physiology, University of Nairobi. P.O. Box 30197 (00100) Tel. +254 733899421 Nairobi, Kenya e-mail: npatel@uonbi.ac.ke