University of Groningen Adaptation after mild traumatic brain injury van der Horn, Harm J. IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2017 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): van der Horn, H. (2017). Adaptation after mild traumatic brain injury: The role of structural and functional brain networks [Groningen]: Rijksuniversiteit Groningen Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date: 05-12-2017
ADAPTATION AFTER MILD TRAUMATIC brain injury: The Role of Structural and Functional Brain Networks Hans van der Horn
ISBN (e-book): 978-90-367-9672-9 ISBN (printed book): 978-90-367-9673-6 Cover design: Kalle Wolters (kallixters@gmail.com) Layout: Rikkert Veltman Media Producties (rikkert.veltman@gmail.com) Printed by Ipskamp Printing Hans van der Horn. All rights reserved. No part of this publication may be reproduced, stored in, or introduced into a retrieval system, or transmitted in any form or by any means (electronic, mechanical, photocopying, recording, or otherwise) without prior permission from the author. This research was financially supported by the Dutch Brain Foundation (Hersenstichting Nederland). Publication of this dissertation was financially supported by the University Medical Center Groningen (UMCG) and the University of Groningen. Conference attendendances were financially supported by the Research School of Behavioral and Cognitive Neurosciences (BCN).
Adaptation After Mild Traumatic Brain Injury The Role of Structural and Functional Brain Networks Proefschrift ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen op gezag van de rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promoties. De openbare verdediging zal plaatsvinden op woensdag 21 juni 2017 om 12.45 uur door Harm Jan van der Horn geboren op 23 juli 1985 te Groningen
Promotores Prof. dr. J. van der Naalt Prof. dr. J.M. Spikman Beoordelingscommissie Prof. dr. H.P.H. Kremer Prof. dr. R.P.C. Kessels Prof. dr. ir. N.M. Maurits
Paranimfen M.E. Scheenen M.E. de Koning
Contents 1. 2. 3. 4. 5. 6. 7. 8. 9. General Introduction Review: Brain Networks Subserving Emotion Regulation and Adaptation After Mild Traumatic Brain Injury (J Neurotrauma 2016 Jan 1;33(1):1-9) Structural MRI studies: Clinical Relevance of Microhemorrhagic Lesions in Subacute Mild Traumatic Brain Injury (submitted) Altered Wiring of the Human Structural Connectome in Adults with Mild Traumatic Brain Injury (J Neurotrauma 2017 Mar 1;34(5): 1035-1044) Functional MRI studies: Post-concussive Complaints After Mild Traumatic Brain Injury Associated with Altered Brain Networks During Working Memory Performance (Brain Imaging Behav. 2016 Dec 10(4):1243-1253) Brain Network Dysregulation, Emotion and Complaints After Mild Traumatic Brain Injury (Hum Brain Mapp. 2016 Apr;37(4):1645-54) Graph Analysis of Functional Brain Networks in Mild Traumatic Brain Injury (PLoS One 2017 Jan 27;12(1):e0171031) The Default Mode Network as a Biomarker of Persistent Complaints After Mild Traumatic Brain Injury: A Longitudinal fmri Study (submitted) General Discussion and Future Perspectives References Nederlandse samenvatting (Summary in Dutch) Dankwoord (Acknowledgements) List of Publications Curriculum Vitae 9 15 31 39 65 91 109 129 149 157 185 191 197 201
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