Novel Psychoactive Substances. Some Definitions

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Novel Psychoactive Substances Training for Professionals Some Definitions From Legal highs - a term given to substances that are used recreationally but are not controlled under the Misuse of Drugs Act (1971), not licensed for legal use, and not regulated as a medicine (Medicines Act 1968). Substances designed to act like existing illegal drugs like cannabis, amphetamines or LSD. 1

TO Novel Psychoactive Substances (or New Psychoactive Stimulants or NPS) - This is an official term for newly produced chemicals. However, as more of these substances are becoming controlled, this term is now used to describe substances that were either recently made illegal or are still legal, e.g. ketamine is sometimes referred to as a NPS Research Chemicals -These are drugs that have a purpose for research but are also used recreationally (for fun). It is also a label put onto newly made drugs to bypass the laws. By stating that they are not for human consumption, or that they are bath salts or room deodoriser etc., sellers get away with selling it legally. Don t forget Just the fact that a substance is sold as legal, doesn t mean that it s safe - you can t really be sure what s in a legal high that you ve bought, or been given, or what effect it s likely to have on you Many 'legal highs' aren't legal at all - they can contain controlled, dangerous substances. You can't tell what's in a 'legal high' just by looking it!!! It's really not possible to know what is a safe dose!!! 2

The Effects: Different NPS have different effects on your body and mind. Like other psychoactive drugs, they fall mostly into three main categories: STIMULANTS DEPRESSANTS / SEDATIVES (or downers) PSYCHEDELICS (or hallucinogens) Stimulant like drugs: These NPS give similar effects to speed, cocaine or ecstasy. They give you a 'buzz' - you might feel full of energy and confidence if you take them. But they can also make you feel: paranoia confusion hallucinations Delusions Heart problems Difficulties sleeping and eating!!! Difficult to keep control of use may feel down when stop using!!! 3

BZP - illegal synthetic stimulant with effects similar to amphetamine. They are pills of various colours and shapes which give a speed type buzz. They are also used as an adulterant or substitute for drugs such as ecstasy and cocaine. Became illegal (Class C) in 2009. MEPHEDRONE - strong stimulant. It was the first high profile legal high. white-powdered stimulant and is generally an amphetamine like substance. It is mainly snorted, sometimes swallowed and acts on the central nervous system. Prolonged use will lead to addiction which can be acute. Possession and supply became illegal in UK in April 2010. BENZO FURY - Brand of new legal stimulant which may contain almost anything. It is a granular white or brownish powder which is snorted or bombed. It can also come in pill form. It is relatively cheap to buy ( 30 a gram). It is a brand new drug and its harms and dangers are largely unknown but there have been reports of overdosing and collapse. May become a banned substance soon. MDAI (Sparkle) - Legal stimulant and club drug presenting as a granular, brownish powder which is snorted or bombed. Effect close to ectasy but very little is known about it and its harms and dangers are unclear. Very cheap ( 20 a gram), it is legal to buy and sell at present. ETHYLPHENIDATE Legal crack that has emerged in the drug market in the last year or two. It is a white-powdered stimulant and is generally an amphetamine like substance. It is mainly snorted, sometimes swallowed and acts on the central nervous system causing rapid heartbeat but also some euphoria which has been described as a mild form of cocaine but price very low (about 10-15 per gram). 4

KHAT KHAT Not considered as legal highs since June 2014 when it became a controlled class C drug in the UK. leafy green plant containing two main stimulant drugs which speed up your mind and body. Their main effects are similar to, but less powerful than, amphetamine (Speed). Used mostly in North East Africa, and the Arabian Peninsula and by expatriate communities from these regions The key effects and risks include: People feel more alert, happy and talkative. It suppresses the appetite. Risk of significant liver toxicity from excessive use, Reports of dependent users (though not physically addictive) It may cause disrupted sleep and make pre-existing mental health problems worse Sedative / Depressant like drugs: Act similarly to cannabis, benzodiazepines (drugs like diazepam or Valium), or GHB/GBL, in that they can make you feel euphoric, relaxed or sleepy. These may make you feel: Relaxed Unselfconscious The health risks are: Accidental comas and fatal overdose (especially when mixing drugs, particularly alcohol) Tolerance (needing more to get the same effect) Addiction Nasty withdrawal symptoms (these can be dangerous and you may need special treatment to come off the drug safely) 5

GHB/GBL (G)- GBL (Gammabutyrolactone) GHB (Gammahydroxybutrate) are club/dance drugs which have been available for the last ten years or so. A small dose can have a powerful sedating effect Mixing it with any alcohol is extremely dangerous (can lead to unconsciousness and coma) They present as clear liquids, GBL was manufactured as an industrial solvent for cleaning video tape, metals or removing spray paint. Measuring an accurate dose is vital to prevent a bad reaction which can include physical collapse. Very regular use over time will lead to addiction. GHB was banned in the UK in 2003 so the market switched to GBL which remained legal until 2009. High use in gay men and students Cost typically 15 for 30ml bottle of pure (99%) GBL (supplied with pipette for accurate dosing) PHENAZEPAM (Bonsai, Benzos, Russian Valium) - extremely strong sedative belonging to a class of drugs known as benzodiazepines like Valium (diazepam). They work by slowing down the central nervous system. Much stronger drug than Valium (both Class C) and is not a prescribed drug in UK. Either a liquid, in crystals or a pill. It can keep that person in a semi-conscious state for some days. It is sometimes taken as a downer after a long session on cocaine, ecstasy or mephedrone. Regular use can induce dependence. It is usually bought through the internet. 6

Synthetic cannabinoids : Spice, Black Mamba, Kronik, Clockwork Orange, Exodus Damnation Downer-type drug with psychedelic effect These are synthetic drugs that are designed to mimic the action of the active chemical found in cannabis (THC) The chemical is sprayed onto plant material which is then packaged and made to appear similar to bags of weed, giving the false impression of a natural substance. The labelling usually states not for human consumption on the packet. It is a powerful drug to smoke and the high is intense and trippy. It may only take one or two tokes to get the full effect. The peak of the high fades after 20-30 minutes. Some reports of vomiting and headaches. You may lose good control over you limbs and feel dizzy. You may feel paranoid and there is a risk of panic attack. Psychedelic-like drugs: These NPS give you similar reactions to LSD, magic mushrooms, ketamine These drugs may: Change your perceptions (so you might experience colours, sounds, thoughts, smells, touch and sight in different ways) Make you feel disoriented and prone to accidents Dissociative effect leading to panic attacks (bad trips) Health risks: Exacerbation of existing mental health problems like anxiety or depression Increase in body temperature Convulsions Circulatory problems 7

KETAMINE - essentially an anaesthetic which can also have hallucinogenic effects. The media usually call it the horse tranquiliser. usually a white, grainy, odourless powder, but also occasionally comes in liquid form. Taking it will result in physical numbness and disconnection with your surroundings. In large doses it can lead to intense hallucinations and a sort of out-of-body experience known as a K-hole. Prolonged use can cause addiction and other serious health problems, particularly with the bladder, as well as affecting memory. The cost varies regionally but is as low as 10 a gram in many areas. Alcohol and ketamine are a bad mix and often causes vomiting. METHOXETAMINE (MXE Mexxy)- very similar to Ketamine and it has been marketed safer alternative. In February 2013 it became a Class B drug. Gives a form of out of body experience and is also hallucinogenic Reported to be stronger and longer lasting than Ketamine. Experienced drug users may enjoy its effects but relative novices often find it too powerful and unpleasant. White or off-white crystalline powder which is snorted or swallowed. It costs about 20 a gram which is enough for at least 20 lines. So little is known about this drug. It is illegal to supply and possess. 8

Summary of the risks: Stimulant NPS can make user feel overconfident and disinhibited Can induce feelings of anxiety, panic, confusion, paranoia Can even cause psychosis, which can lead user to put their own safety at risk. can put a strain on the heart and nervous system. They may give their immune system a battering so they might get more colds, flu and sore throats. User may feel quite low for a while after they have stopped using them. Overdose (Benzo Fury) Addiction (mephedrone) Summary of the risks: Sedative NPS can reduce inhibitions and concentration slow down reactions and feel lethargic, forgetful or physically unsteady, increasing risk of accidents. unconsciousness, coma and death, particularly when mixed with alcohol and/or with other downer drugs (GHB/GBL Spice Kronik) Some people feel very anxious soon after they stop taking downers, and if a severe withdrawal syndrome develops in heavy drug users, it can be particularly dangerous and may need medical treatment. High risk of addiction(ghb/gbl) 9

Summary of the risks: Psychedelic NPS Can cause confusion, panics and strong hallucinatory reactions ( bad trips ) Can make user behave erratically and put their own safety at serious risk including from self-harm. Some psychedelic drugs create strong dissociative effects, feeling like mind and body are separated. Risk of acting carelessly or dangerously particularly in an unsafe environment. Addiction (ketamine) Haemorrhage from bladder (ketamine) Harm Reduction: Best protection is simple: Don't take them! Then here are some tips to help reduce the risks: Do some research (read online info and reports from other people but these sources aren t necessarily trustworthy) Use with a friend who hasn t taken anything and can call for help if necessary Take a 'test dose' first a tiny dab or half a pill then wait at least 3 hours before taking any more Avoid mixing any substance with other drugs (including alcohol) Make sure fully recovered from your experience before doing it again Plenty of sleep and healthy food afterwards Don t be afraid to ask for help if needed, and tell emergency services exactly what you ve taken. The way you take drugs also has a big impact on the risks you run (different routes different risks). 10

Harm minimisation Please also refer to additional hand-out If in doubt contact emergency services! North Westminster Drug & Alcohol Service NWDAS is a free and confidential service offering advice, support and treatment to individuals and families affected by substance misuse. Outreach satellite service 1:1 support Group work Clinical interventions Counselling Alternative Therapies Education, Training & Employment Support for families & carers Support for those affected by DV Service User Involvement & Peer Mentors 11

The Club Drug Clinic The clinic offers a help for people affected by these kinds of drugs and it mainly deals with LGBT. They offer: A General assessment about club drugs A psychiatric assessment (they prioritize psychosis, or mental health or harm risks) Psychological keywork Harm reduction (structured one) also comprehensive of detox. One-to-one key working to address immediate drug and alcohol support needs Referral to detox clinics and prescribing centres Referral to a counselling service Drop-ins to discuss drug and alcohol issues, sexual health and steroid use issues A telephone advice helpline Training and support for healthcare professionals Helpful Resources: For specific harm reduction advice: http://www.whynotfindout.org For information about treatment approach: http://neptune-clinical-guidance.co.uk/wp- content/uploads/2015/03/neptune-guidance- March-2015.pdf For basic drug or alcohol information and advice: http://www.talktofrank.com 12

Q&A 13