8th Meet The Professor. Advanced International Breast Cancer Course (AIBCC)

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Sezione di Oncologia [ Meet the Professor ] 8th Meet The Professor. Advanced International Breast Cancer Course (AIBCC) November 15-17, 2012 The Conference will include: 1) Lectures: Internationally recognized speakers provide a balanced overview of selected topics 2) Round Tables: Panel of experts discusses items which require a multi-faceted approach 3) Clinical Case Discussions: Difficult or controversial cases related to the diagnostic or therapeutic management of early and advanced breast cancer will be presented. All participants will be requested to express their vote among a predefined list of options. Expert panelists will then provide their opinion and discuss the audience choices. 4) Highlights: Internationally recognized speakers give an update of significant advances presented at major meetings (ASCO, ESMO, SABCS) on preselected topics 5) Debates: A speaker will illustrate a clinical case where the use of a specific technique, diagnostic tool or treatment might change patient management. Two experts will take a different view on the clinical utility of this approach. 1 di 6

[ Draft Program] Sezione di Oncologia Thursday, November 15 8.30 Registration Chairmen: 9.30 Lecture 1 Biological evolution of molecular markers in breast cancer Jonas Bergh 10.00 Lecture 2 Clinical implications of biomarker changes Sibylle Loibl 10.30 Lecture 3 Proliferative markers: prognostic and predictive role Giuseppe Viale 11.00 Coffee break 11.30 Clinical case discussion 1. Biopsy of metastases in breast cancer patients Chairmen:TBD Presenters:TBD Panelists: Jonas Bergh, Pier Franco Conte, Fikri Icli, Gabriel N. Hortobagyi, Sibylle Loibl, Philip Poortmans, Giuseppe Viale 13.00 Lunch 14.00 Debate 1. How far can we go to minimize therapy of primary breast cancer? Chairman: Gabriel N. Hortobagyi Pro: TBD, Roberto Orecchia Contra: TBD, Philip Poortmans 15.40 Coffee break 16.00 Lecture 4 Early Breast Cancer: systemic treatment. An update. Gabriel N. Hortobagyi 16.40 Debate 2. Intensive follow up after primary curative therapy Chairmen: TBD Pro: Pier Franco Conte Contra: Giovanni Apolone 18.00 Adjourn 2 di 6

Friday, November 16 Sezione di Oncologia 8.30 Lecture 5 Primary systemic therapy: biological and clinical end points Valentina Guarneri 9.00 Lecture 6 Breast reconstruction and radiation therapy Philip Poortmans 9.30 Clinical case discussion 2. Management after primary systemic therapy Chairmen: TBD Presenters:TBD Panelists: Valentina Guarneri, Gabriel N. Hortobagyi, Jacek Jassem, Sibylle Loibl, Philip Poortmans 11.00 Coffee break 11.30 Lecture 7 Preservation of fertility and pregnancy after breast cancer Lucia del Mastro 12.00 Lecture 8 Male breast cancer Fatima Cardoso 12.30 Lunch 13.30 Lecture 9 Management of advanced breast cancer patients: how to translate scientific advances into daily practice Miguel Martin 14.00 Lecture 10 Management of elderly breast cancer patient Vittorina Zagonel 14.30 Lecture 11 New bone targeting agents Robert Coleman 15.00 Coffee break 15.30 Lecture 12 Clinical and ethical challenges in treatment decision Richard L. Theriault 16.00 Ceremony for the presentation of the Award for advances in breast cancer research, the Monica Boscolo Research Grant and the Patrizia Rossi merit award. 16.30 Lecture of the awardee 17.15 Adjourn 3 di 6

Sezione di Oncologia Saturday, November 17 8.30 Round Table - Strategies to overcome resistance in BC molecular subtypes - HR + disease Stephen Johnston - HER2+ disease David Kayath - Triple negative Ana Maria Gonzalez-Angulo 10.00 Lecture 13 Clinical genomics for personalized cancer medicine Luca Gianni 10.30 Lecture 14 Immunotherapy for breast cancer: premises and promises Christof Zielinski 11.00 Coffee break 11.15 Highlights from ASCO, SABCS, EBCC 11.15 Round Table Challenges in drug development and accessibility. A view from different perspectives: scientists, clinicians, pharma representatives, regulatory officials, payers, patients, media representatives Adriana Bazzi, Pier Franco Conte, Francesco De Lorenzo, Luca Gianni, Paolo Paoletti, Jean Pierre Bizzari, John Hohneker, Gabriel N. Hortobagyi, David Kayath, Sergio Pecorelli 13.00 Adjourn and final evaluation questionnaire [ Addressed to] Oncologists, radiologists, radiation oncologists, pathologists, surgeons [ Aims] Mortality from breast cancer is rapidly declining in most countries worldwide and nowadays breast cancer patients have a great chance for cure. These results are extraordinary if we remember that breast cancer is by and large the most frequent tumor among females and it is still considered one of the big killers. Now that we are so close to our objectives, we must maximize our efforts to provide a more personalized approach to the individual patient, to optimize the appropriate use of resources and to develop innovative therapies for the patients not yet cured. With these goals in mind, the Programme of this international Conference includes lectures on the molecular characterization of primary and metastatic tumors, update management of early and advanced disease, strategies to overcome resistance to available therapies, innovative therapies, preservation of fertility and treatment of male breast cancer. Clinical case discussions and debates are also planned to discuss topics which require a multifaceted approach or are matter of controversy. This 8 th Breast Cancer Conference includes a highly qualified international faculty, but will maintain its characteristics of a friendly forum where international opinion leaders and attendees will exchange experiences and share the most exiting advances. 4 di 6

Sezione di Oncologia In order to reward scientific excellence and to foster international cooperation, the International Scientific Committee of the 8 th AIBCC will award the third International Prize for Breast Cancer Research to a scientist who has published a breakthrough paper in the previous year and the Monica Boscolo Research Grant to an Italian scientist for a research project to be conducted in cooperation with a foreign institution. The Local Organizing Committee will award the Patrizia Rossi prize to the best thesis on breast cancer from a graduate in medicine or postgraduate in medical oncology from Italian universities. We welcome medical oncologists, pathologists, breast surgeons, radiation oncologists and basic scientists to listen to breast cancer leaders and to exchange experiences in a friendly atmosphere. PierFranco Conte, Gabriel N. Hortobagyi [ Directors ] Pier Franco Conte Italy Gabriel N. Hortobagyi Department of Breast Medical Oncology University of Texas - MD Anderson Cancer Center Houston (USA) [ Scientific Committee] Valentina Guarneri Integrated Department of Oncology, Hematology and Respiratory Diseases University Hospital of Modena University of Modena and Reggio Emilia (I) Fikri Içli Oncology Research and Treatment Center Ankara University (T) Jacek Jassem Department of Oncology and Radiotherapy Medical University of Gdansk (PL) Stephen Johnston NIHR Biomedical Research Centre for Cancer Royal Marsden NHS Foundation Trust & Institute of Cancer Research London (UK) David Khayat Medical Oncology Department Salpetriere Hospital Paris (F) 5 di 6

Sibylle Loibl German Breast Group University Frankfurt (D) Sezione di Oncologia Miguel Martin Medical Oncology Service Hospital Universitario Gregorio Maranon Madrid (S) Philip Poortmans Department of Radiation Oncology Dr. Verbeeten Instituut Tilburg (NL) Christoph Zielinski Clinical Division of Oncology Medical University - General Hospital Vienna (A) 6 di 6