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Aim of the conference Cardiovascular diseases are the main cause of morbidities and mortality world wide, and related risk factors are particularly increasing. Hypertension and its complications, such as heart failure, cerebrovascular events and atrial fibrillation, are mainly responsible for disabilities and numerous diseases. The implementation in clinical practice of a modern management approach is crucial, with both prevention and intervention strategies required to improve patient care while balancing the socio-economic burden. EXCEMED, in partnership with the Università degli studi di Ferrara and Università degli studi di Bologna is organising the meeting entitled Practical course on the management of cardiology from cell to patient: The experience of the Centre for Prevention and Care of Cardiovascular Diseases of the University of Ferrara to highlight to the physicians dealing with patients having cardiovascular risk factors or cardiovascular diseases the crucial role of a multidisciplinary approach in diagnosis, treatment and management of patients. This educational activity will offer the opportunity to learn from and to interact with a recognised experienced multidisciplinary team, lead by Prof. Roberto Ferrari, providing the participants with knowledge and information on diagnosis and managing patients. Learning objectives After attending the meeting, participants will have up-to-date knowledge about the research and clinical management of diabetes and thyroid disorders, and particularly will be able to: Explain the role of beta-blockers in cardiovascular treatment Apply techniques such as electrophysiology, haemodynamics, echocardiography and imaging within clinical care Describe and appropriately apply the different guidelines on use of beta-blockers Discuss the experimental cardiology related to bisoprolol and the structure of clinical trials Target audience Cardiologists and internists Accreditation An application has been to the EACCME for CME accreditation of the Practical course on the management of cardiology from cell to patient: The experience of the Centre for Prevention and Care of Cardiovascular Diseases of the University of Ferrara. 1

Scientific organiser Roberto Ferrari Chair of Cardiology Scientific secretariat EXCEMED - Excellence in Medical Education Salita di San Nicola da Tolentino, 1/b 00187 Rome, Italy Associate Programme Manager: Sonia Rebustini Tel.: +39-06-420 413 312 Fax: +39-06-420 413 677 E-mail: info@excemed.org EXCEMED is a Swiss Foundation with headquarters in 14, rue du Rhône, 1204 Geneva, Switzerland Organising secretariat Fondazione "Anna Maria Sechi per il Cuore" (FASC) 2

List of faculty members Giorgio Aquila LTTA Centre, Matteo Bertini Claudio Borghi Department of Internal Medicine University of Bologna Bologna, Italy Cristiana Caliceti LTTA Centre, Gianluca Campo Claudio Ceconi Roberto Ferrari Chair of Cardiology 3

List of faculty members Alessandro Fucili Gabriele Guardigli Patrizia Malagutti Donato Mele Cristina Morelli LTTA Centre, Claudio Rapezzi University of Bologna Bologna, Italy Paola Rizzo 4

List of faculty members Matteo Tabaldi Raffaella Vergura LTTA Centre, 5

Scientific programme

Scientific programme Thursday, 11 September 2014 Session I Heart Rate and Beta-Blockers 17.30 The history and unknown aspects of heart rate R. Ferrari () C. Ceconi () 18.00 Are beta-blockers still a milestone cardiovascular treatment in 2014? C. Rapezzi (Bologna, Italy) 8

Scientific programme Friday, 12 September 2014 Session II A Practical Approach 08.30 Participation at the daily clinical meeting and discussion of clinical cases 09.30 Rotation of subgroups to visit and discuss the following subspecialties: a) Echo and imaging lab D. Mele () and P. Malagutti () b) Electrophysiology lab R. Ferrari () and M. Bertini () c) Haemodynamic lab M. Tebaldi () and G. Campo () d) ICU and heart failure centre A. Fucili () and G. Guardigli () 13.30 Lunch 15:30 Rotation of subgroups to demonstrate the following sub-s pecialities: a) Experimental cardiology related to Bisoprolol P. Rizzo () and G. Aquila () b) Experimental cardiology related to Bisoprolol R. Ferrari () and C. Caliceti () 17:15 Coffee break 17:30 Rotation of subgroups to demonstrate the following: a) The structure of a clinical trial (related to SIGNifY and CIBIS I,II,III) C. Morelli (), R. Vergura () and R. Ferrari () 9

Scientific programme Saturday, 13 September 2014 Session III 10:00 Presentation of the centre activities and the school for clinical researchers R. Ferrari () 10:30 Fondazione Anna Maria Sechi per il Cuore (FASC) projects and European Heart for Children (EHC) R. Ferrari () 11:00 Coffee Break 11:15 The different hypertension Guidelines on Beta-Blockers who is right? C. Borghi (Bologna, Italy) 11.45 Closing remarks and end of the course 10

General information Venues Palazzo Tassoni Faculty of Architecture Via della Ghiara, 36 Via Aldo Moro, 8 Cona, Centro per la Prevenzione e Cura delle Malattie Cardiovascolari Corso Ercole I d'este, 32 Language The official language of the conference will be English Register to EXCEMED website: www.cardiometabolic.excemed.org follow us on www.twitter.com/excemed_cardio 11

All EXCEMED programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. This programme is made possible thanks to educational grants received from: Arseus Medical, Besins Healthcare, Bristol-Myers Squibb, Celgene, Centre d Esclerosi Multiple de Catalunya (Vall d Hebron University Hospital), Centre Hépato-Biliaire (Hôpital Paul Brousse), Croissance Conseil, Cryo-Save, Datanalysis, Dos33, Esaote, Ferring, Fondazione Humanitas, Fundación IVI, GE Healthcare, GlaxoSmithKline Pharmaceuticals, IPSEN, Italfarmaco, International Society for Fertility Preservation, Johnson & Johnson Medical, K.I.T.E., Karl Storz, Lumenis, Merck Serono Group, PregLem, Richard Wolf Endoscopie, Sanofi-Aventis, Stallergenes, Stopler, Teva Pharma, Toshiba Medical Systems, Université Catholique de Louvain (UCL), University of Catania. Personal data treatment - Informative document In compliance with the article 13 of Italian Legislative Decree n. 196, 30 June 2003, we inform you that your personal data will be processed, with or without the use of electronic or automated means, via suitable tools that will guarantee security and confidentiality. Personal data from you supplied will be communicated to Continuing Medical Education Accreditation Authorities, to agencies that will take care of the whole accreditation process and agencies that will take care of the logistics of the event; should we not receive the below requested data, we will not be able to process your registration to the event. At anytime you may exercise your rights as laid down in the art. 7 of Italian Legislative Decree n. 196, 30 June 2003 of the Italian Law, by contacting the Data Controller EXCEMED (Salita di San Nicola da Tolentino, 1/b - 00187 Rome - Italy) in the person of Data Processor, Michèle Piraux. 12

Improving the patient's life through medical education www.excemed.org EXCEMED - Excellence in Medical Education Representative Office Salita di San Nicola da Tolentino 1/B 00187 Rome, Italy. T +39.06.420.413, F +39.06.420.413.677 Headquarters EXCEMED 14, Rue du Rhone, 1204 Geneva, Switzerland Copyright EXCEMED, 2014. All rights reserved.