Migraine and stroke. Understanding migraine and stroke. Stroke risk and migraine. Migrainous infarction

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Call the Stroke Helpline: 0303 3033 100 or email: info@stroke.org.uk Migraine and stroke Migraines have not been shown to cause stroke, but if you have migraine with aura you have a very slightly higher risk of stroke. This guide explains more about migraine, and lists some useful organisations. Understanding migraine and stroke Stroke and migraine both happen in the brain, and sometimes the symptoms of a migraine can mimic a stroke. However, the causes of the symptoms are different. A stroke is due to damage to the blood supply inside the brain, but migraine is thought to be due to problems with the way brain cells work. In a stroke, the blood supply to part of the brain is cut off, killing brain cells. This causes permanent damage to the brain, and can have long-lasting physical, cognitive and emotional effects. A migraine causes pain and sensory disturbances, but the changes inside the brain are usually temporary. The relationship between migraine and stroke is complex. The symptoms can sometimes seem similar (see How do I tell the difference between migraine and stroke later in this guide), and they may share some underlying risk factors. Migrainous infarction Occasionally migraine and stroke can occur at the same time, but there is no evidence to suggest that one causes the other. Migrainous infarction is the term given to an ischaemic stroke (clot) that happens during a migraine. This tends to happen alongside prolonged aura symptoms, but is extremely rare. Stroke risk and migraine If you have migraine with aura, you are about twice as likely to have an ischaemic stroke in your lifetime compared to those without migraine. However, the overall risk linked to migraine is still very low, and you are far more likely to have a stroke because of other risk factors like smoking and high blood pressure. If you have migraine, your GP or nurse can give advice on reducing your risk of a stroke from any other health conditions you may have, like high blood pressure, diabetes, atrial fibrillatrion or high cholesterol. They can also support you with making lifestyle changes such as stopping smoking, losing weight, healthy eating and exercise. For more information visit stroke.org.uk 1

Women and migraine Taking the combined oral contraceptive pill (combi pill) increases the risk of a stroke in women who have migraine with aura. Because of this, women who have migraine with aura are not usually given the combi pill. If you have migraine without aura you should be able to take the combi pill, unless you have other risk factors like smoking or being overweight. Other health conditions Some health conditions are linked to migraine. For example, CADASIL (a rare genetic disorder), and the auto-immune conditions antiphospholipid syndrome and Lupus, are linked to a higher risk of stroke, and people with these conditions are also more likely to have migraine. What is migraine? A migraine attack can have a wide range of symptoms. For many people the key symptom is a moderate or severe headache. Usually this is felt as a throbbing pain on one side of your head. This is often accompanied by other symptoms such as nausea and vomiting, and sensitivity to light or sound. Migraine affects around one in every 15 men, and one in five women. People of all ages are affected by migraine, but the condition often begins in young adulthood. It often runs in families, and many people with migraine have a close relative with the condition. Some people have several migraines a week; others may have years between migraine attacks. Symptoms can last from a few hours to several days, but you could also feel very tired for up to a week after an attack. The main types of migraine Symptoms like paralysis, sudden sight loss and confusion can be signs of a stroke. If you have any of these symptoms and you have not been diagnosed with migraine, you should call 999. Migraine without aura Between 70% and 90% of the population with migraine have this type, which is sometimes called common migraine. It consists of a headache with other symptoms such as nausea and sensitivity to light, sound or smell. The other symptoms usually begin at the same time as the headache, and disappear once the headache goes. Many people feel irritable and need to rest in a dark room or sleep. Migraine with aura About 30% of people with migraine have migraine with aura (sometimes called classical migraine). Some people have both types. Attacks typically begin with an aura consisting of one or more of the following symptoms which develop gradually over five to 30 minutes and last less than one hour. The headache can occur with or after the aura. Types of aura Visual changes. This is the most common aura symptom, and the changes can include flashing lights, zig-zags, sparks or blank spots. These can appear on one side or centrally, and commonly expand and move across 2 Call the Stroke Helpline on 0303 3033 100

your field of vision. Visual changes such as flashing lights can also be signs of acute eye disease, so if you get any of these symptoms and have not been diagnosed with migraine, visit your optician or GP urgently. Sensations such as pins and needles, tingling or numbness, weakness or a spinning sensation or vertigo. Less commonly, you may have difficulty speaking or hearing, and feel fear or confusion and even have paralysis. Whether or not you have a migraine aura, you may experience some different symptoms hours or days before a migraine attack. These can include changes in mood and energy levels, aches and pains and sensitivity to light or sound. These are called prodromal or premonitory symptoms. Migraine aura without headache Also known as a silent migraine, this is an aura without the headache. Rare types of migraine There are some rare types of migraine, which are also classed as migraine with aura. hearing problems, including ringing in the ears tingling in the hands and feet dizziness vertigo. People may experience these symptoms either ahead of or alongside typical migraine symptoms. Hemiplegic migraine Hemiplegia means paralysis on one side of the body, and weakness or paralysis on one side is a key symptom of this type of migraine. Other symptoms might include numbness or pins and needles, visual problems, confusion and speech problems. These problems usually go away within 24 hours, but they may last a few days. A headache usually follows. If you have a parent with hemiplegic migraines then you have about a 50% chance of having this type of migraine yourself, known as familial hemiplegic migraine (FHM). In some families with FHM, problems have been found with particular genes which affect how the brain cells communicate with each other. Migraine with brainstem aura Previously known as basilar-type migraine, people with this condition experience two or more of the following symptoms before a migraine: visual disturbances, including double vision speaking difficulties For more information visit stroke.org.uk 3

What causes a migraine? Migraine often runs in families, and if one or more close relatives experience migraine, it is more likely that you will too. Migraine triggers There are various triggers that can lead to a migraine attack, including: emotional: such as stress, anxiety or depression physical: such as tiredness or tension, particularly in the neck and shoulders hormonal: some women experience migraine around the time of their period dietary: missing a meal, drinking alcohol or caffeinated drinks, and eating certain foods such chocolate or cheese environmental: such as bright lights or a stuffy atmosphere medicines: including some sleeping tablets, and the combined contraceptive pill Often it takes more than one trigger to lead to an attack, for example being under emotional stress and missing a meal. When migraine mimics stroke This information is a guide to some of the stroke-like symptoms of migraine, but it is not intended as a way of diagnosing migraine or stroke. You should get individual advice from a medical professional if you have migraine symptoms. If you have any stroke symptoms you must call 999. The symptoms of some types of migraine can mimic stroke, such as hemiplegic migraine, which can cause weakness down one side. Migraine auras can be confused with transient ischaemic attack (TIA), where someone has stroke symptoms that pass in a short time. For instance, a migraine with only a visual aura but no headache may be mistaken for TIA. Like a stroke, a migraine can be sudden and can lead to mild confusion. However, migraine aura symptoms tend to develop relatively slowly and then spread and intensify, while the symptoms of a TIA or stroke are sudden. Migraine can sometimes be mistaken for a stroke caused by bleeding on the brain, called a subarachnoid haemorrhage (SAH), which is often characterised by a sudden, very severe headache. Unlike SAH, migraine headache is usually one-sided and throbbing, slow to come on and lasts for a shorter period of time. Vomiting usually starts after a migraine headache starts, but is likely to happen at the same time as headache during a SAH. Patients with a SAH also develop neck stiffness, which is uncommon during a migraine attack. 4 Call the Stroke Helpline on 0303 3033 100

Migraine diagnosis and treatment Diagnosing migraine Migraine is diagnosed by piecing together information about your symptoms and identifying patterns over time. Your GP will do a number of tests checking your vision, reflexes, coordination and sensations. They will ask you to keep a diary of your migraine symptoms and factors such as what you ate and how you slept leading up to them. This may help you identify and avoid your triggers. You should also record any medicines you are already taking. Painkiller over-use makes migraines difficult to treat. Managing migraine Some people are able to avoid their triggers and so eliminate migraine that way. Many people find that ordinary painkillers such as paracetamol, ibuprofen and aspirin reduce the pain of their migraine headache. Do not take painkillers every day for a migraine, as painkiller over-use can cause headaches. Your GP or a specialist can prescribe other treatments such as a migraine medication for headache and nausea. Botulinum toxin type A treatment (often known as Botox) is available for some cases of chronic migraine. For more information about managing migraine, visit www.migrainetrust.org or NHS Choices (see Other sources of help and information). Spotting the signs of a stroke FAST test Face Can the person smile? Has their face fallen on one side? Arms Can the person raise both arms and keep them there? Speech Can the person speak clearly and understand what you say? Is their speech slurred? Time If you see any of these three signs, it s time to call 999. The FAST test helps to spot the three most common symptoms of stroke. But there are other signs that you should always take seriously. These include: sudden weakness or numbness on one side of the body, including legs, hands or feet difficulty finding words or speaking in clear sentences sudden blurred vision or loss of sight in one or both eyes sudden memory loss or confusion, and dizziness or a sudden fall a sudden, severe headache. Stroke can happen to anyone, at any age. Every second counts. If you spot any of these signs of a stroke, don t wait. Call 999 straight away. For more information visit stroke.org.uk 5

Where to get help and information From the Stroke Association Talk to us Our Stroke Helpline is for anyone affected by a stroke, including family, friends and carers. The Helpline can give you information and support on any aspect of stroke. Call us on 0303 3033 100, from a textphone 18001 0303 3033 100 or email info@stroke.org.uk. Read our publications We publish detailed information about a wide range of stroke topics including reducing your risk of a stroke and rehabilitation. Read online at stroke.org.uk or call the Helpline to ask for printed copies. Glossary Aura = a range of symptoms that start before a migraine headache, often including a visual disturbance Hemiplegic migraine = a type of migraine that involves weakness or paralysis on one side of the body as well as other symptoms Ischaemic stroke = a stroke caused by a blockage Migraine with brainstem aura = migraine with a number of other symptoms such as visual or hearing problems and pins and needles (previously known as basilar-type migraine) Subarachnoid haemorrhage (SAH) = bleeding on the surface of the brain Other sources of help and information Migraine Action Website: www.migraine.org.uk Tel: 08456 011 033 Membership organisation providing information and advice about all aspects of migraine. The Migraine Trust Website: www.migrainetrust.org Tel: 020 7631 6970 Leading patient support and research charity for migraine. Can provide details of specialist migraine clinics. NHS Choices Website: www.nhs.uk The official website of the NHS. Gives information on hundreds of health conditions, including migraine and stroke. 6 Call the Stroke Helpline on 0303 3033 100

Keeping in touch At the Stroke Association, we understand that the impact of a stroke can turn everything upside down in an instant, not just for the stroke survivor but for their loved ones too. Keep in touch and find out more about our work. This includes groundbreaking research developments, other services that might benefit you and opportunities to get involved with appeals, campaigns or volunteering for the Stroke Association. We are proud to be the leading stroke charity in the UK, changing the world for people affected by stroke. As you may know, our vital work covers many areas, including providing support and information to stroke survivors and their families, funding research into stroke treatment and care, and campaigning to raise awareness of stroke. We are determined to conquer stroke, but we cannot do it alone. To keep in touch, either fill out our online contact form at stroke.org.uk/signup or complete your details below and send them to our freepost address: Freepost RSZL-SAUL-GRBK Keeping in touch Life After Stroke Centre Church Lane Bromsgrove Worcestershire B61 8RA Your contact details I am a: stroke survivor family/friend carer other First name: Surname: Address: Town/city: County: Postcode: Email: Telephone number: I would like to receive Stroke News: online (we ll email you to let you know when an online copy is available) by post (we ll send you a free copy) I m happy for the Stroke Association to keep in touch with news updates and ways to get involved I m happy to be contacted by: (please tick all that apply) post telephone email You can change or stop the way we contact you at any time by calling our friendly Supporter Care team on 0300 330 0740, or by emailing supportercare@stroke.org.uk. For more information visit stroke.org.uk 7

About our information We want to provide the best information for people affected by stroke. That s why we ask stroke survivors and their families, as well as medical experts, to help us put our publications together. How did we do? To tell us what you think of this guide, or to request a list of the sources we used to create it, email us at feedback@stroke.org.uk. Accessible formats Visit our website if you need this information in audio, large print or braille. Always get individual advice Please be aware that this information is not intended as a substitute for specialist professional advice tailored to your situation. We strive to ensure that the content we provide is accurate and up-to-date, but information can change over time. So far as is permitted by law, the Stroke Association does not accept any liability in relation to the use of the information in this publication, or any third-party information or websites included or referred to. Stroke Association 2017 Version 2. Published November 2017 To be reviewed: September 2020 Item code: A01F28 We rely on your support to fund life-saving research and vital services for people affected by stroke. Join the fight against stroke now at stroke.org.uk/fundraising Together we can conquer stroke. The Stroke Association is registered as a charity in England and Wales (No 211015) and in Scotland (SC037789). Also registered in Northern Ireland (XT33805), Isle of Man (No 945) and Jersey (NPO 369). For more information visit stroke.org.uk 8