PEDIATRIC HEPATOLOGY SUMMER SCHOOL organized by the ESPGHAN Hepatology Committee in collaboration with EASL

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PEDIATRIC HEPATOLOGY SUMMER SCHOOL organized by the ESPGHAN Hepatology Committee in collaboration with EASL May 14-17, 2014 Vietri sul Mare (Salerno), Italy

GENERAL INFORMATION Local organizer: Pietro Vajro University of Salerno, Italy email: pvajro@unisa.it Vietri sul Mare ("on the Sea") is a village near Salerno, in the Campania Region of Southern Italy. It is a popular tourist destination and it is a convenient place to visit the Amalfi Coast. The inhabitants call it The First Pearl of the Coast, claiming that the Amalfi coast begins there. Vietri is popular also for the production of ceramics (dishes, flowerpots, vases and tiles) that can be found in restaurants, hotels and homes throughout the Amalfi area. Moreover, Vietri is a convenient starting-point to visit the archeological sites of Pompeii and Haerculaneum. The number of participants is limited to 40. Candidates will be selected based on their CVs, on their academic qualifications and on their publication record. Applications must be sent by 28 February. Selected participants will be advised by March 15 and will have to register by April 13. REGISTRATION FEE Registration 750.00 (VAT 22% included) Registration fee includes: attendance to scientific sessions, congress material, attendance certificate, accommodation for 3 nights in shared double room (single accommodation will be available at extra charge), lunches, coffee breaks and dinners, tour in the surroundings, as indicated in the scientific programme. Travel grants Three travel grants will be awarded to selected candidates from EU and non-eu less advantaged areas. Venue Lloyd's Baia Hotel Via Enrico de Marinis, 2, 84019 Vietri sul Mare (Salerno) How to reach the venue Naples Capodichino airport is served by many daily National and International flights. For those who travel by plane at Capodichino airport, ESPGHAN shuttle buses to the Venue will be scheduled at set times according to the arrivals. Moreover, a public bus service connects Capodichino to Salerno. For participants arriving by train, the nearest high-speed train station is Salerno. ESPGHAN shuttle buses to the Venue will be scheduled at set times according to the arrivals. Moreover, Salerno is well connected to Vietri by public transportation (bus stop in front of the hotel). Organizing Secretariat Scientific Communication srl email: info@jeangilder.it tel +39 081 2296037/460 fax +39 081 0072045

Programme Wednesday 14 May 2014 13.00-14.30 Welcome Lunch 14.30-15.30 The Liver and the Hepatobiliary Tree: development, anatomy and biology issues for the S. Nori, Salerno pediatric hepatologist 15.30-16.00 Common LFTs in pediatric hepatology V. Nobili, Rome 16.00-16.30 BR Pathway & disease (e.g., CN) A. Iolascon, Naples 16.30-17.00 Break 17.00-17.30 Cholestasis: Generalities T. Lamireau, Bordeaux 17.30-18.00 Focus on INTRA-hepatic cholestasis T. Lamireau, Bordeaux 18.00-18.30 Focus on EXTRA-hepatic cholestasis B. Fischler, Stockholm 18.30-19.00 Cholestasis: Management B. Fischler, Stockholm 19.00-20.00 CHOLESTASIS DAY Clinical Cases Interactive Voting Session A. Knisely, London 20.00 Dinner Thursday 15 May 2014 8.30-10.30 Interactive Overview in Pediatric Hepatology Imaging D. Pariente, Paris 10.30-11.00 Break 11.00-11.30 Chronic Viral Hepatitis B B. Fischler, Stockholm 11.30-12.00 Chronic Viral Hepatitis C M.L. Hierro, Madrid 12.00-12.30 Part 1 N. Hadzic, London Autoimmune Liver diseases 12.30-13.00 Part 2 M.L. Hierro, Madrid 13.00-14.30 Lunch 14.30-15.00 Ciliopathies: CHF, cystic lesions, et al. V. Mc Lin, Geneva 15.00-15.30 Neoplasms vs. Nodular/Focal Hyperplasia A. Dezsofi, Budapest Focus on Wilson 15.30-16.00 Disease R. Iorio, Naples 16.00-16.30 Common metabolic liver disease: from Alagille... to Gaucher to Zellwegger Other common Metabolic Liver Diseases N. Hadzic, London 16.30-17.00 Break 17.00-17.30 More rare and/or recently individuated metabolic/genetic liver Part 1 P. Socha, Warsaw 17.30-18.00 diseases Part 2 P. Vajro, Salerno 18.00-18.30 Liver Failure: Diagnosis and Part 1 N. Hadzic, London 18.30-19.00 Management Part 2 U. Baumann, Hannover 19.00-20.00 METABOLIC DAY Clinical cases - Interactive Voting Session A. Knisely, London 20.00 Typical Dinner

Friday 16 May 2014 8.30-9.00 Liver biopsy: ESPGHAN methods & indications A. Dezsofi, Budapest 9.00-9.30 Interpretation of common Pathological findings A. Knisely, London 9.30-10.30 Three interactive histopathological case histories A. Knisely, London and R. Vecchione, Salerno/Naples 10.30-11.00 Break 11.00-11.30 Progressive Liver Diseases: Part 1 V.Nobili, Rome 11.30-12.00 Fibrosis/Cirrhosis/Portal Hypertension Part 2 U. Baumann, Hannover 12.00-12-30 OLT 1: Indications and drugs arsenal V. Mc Lin, Geneva 12.30-13.00 OLT 2: Treatment and Management U. Baumann, Hannover 13.00-13.30 Lunch 13.30-14.00 OLT 3: OLT Complications M.L. Hierro, Madrid 14.00-14.30 OLT 4: Issues for Transition of young adults with S.A.Tizzard, London and Pediatric onset liver diseases and/or OLT P. Vajro, Salerno 15.30-21.30 Visit to Pompeii including dinner Saturday 17 May 2014 8.30-9.00 The steatosic pediatric liver 2014: Part 1 V.Nobili, Rome 9.00-9.30 only NAFLD? An Update Part 2 P. Socha, Warsaw 9.30-10-00 Interactive Discussion on Algorithms Part 1 V. Mc Lin, Geneva 10.00-10.30 for Pediatric Hypertransaminasemia Part 2 T. Lamireau, Bordeaux 10.30-11.00 Break 11.00-12.00 Interactive Discussion upon Odd Cases Faculty and C. Ciacci, Salerno presented by Students vs. Faculty and M. Persico, Salerno 12.00-13.00 Conclusions and leaving 13.00-14.30 Farewell Lunch

Faculty Affiliation Ulrich Baumann Carolina Ciacci Antal Dezsofi Bjorn Fischler Nedim Hadzic M.Loreto Hierro Achille Iolascon Raffaele Iorio Alex Knisely Thierry Lamireau MD, FRCPH, Professor of Paediatric Gastroenterology and Hepatology, Hannover Medical School, Germany ESPGHAN Hepatology Committee Chairman and Representative to the Council MD, Professor of Gastroenterology, Department of Medicine and Surgery, University of Salerno, Baronissi (Sa), Italy MD, PhD, Pediatric Gastroenterologist and Hepatologist, First Department of Pediatrics, Semmelweis University, Budapest, Hungary MD, Specialist in Paediatrics, Senior Consultant in Hepatology, Department of Pediatric Gastroenterology, Hepatology and Nutrition, Karolinska University Children s Hospital, Stockholm, Sweden MD, MSc, FRCPCH, Professor and Consultant in Paediatric Hepatology, Paediatric Centre for Hepatology, Gastroenterology and Nutrition, King's College Hospital, London, UK MD, Specialist in Pediatrics, Service of Hepatology and Transplantation, Pediatric University Hospital La Paz, Madrid, Spain MD, Professor of Medical Genetics, Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, CEINGE- Advanced Biotechnologies, Naples, Italy MD, Assistant Professor, Researcher, Department of Pediatrics, University of Naples Federico II, Italy ESPGHAN Member MD, Consultant Histopathologist, Institute of Liver Studies, King s College Hospital, London, UK MD, Chief of the Hepatology and Gastroenterology Unit, Children s Hospital, Bordeaux Cedex, France

Valerie McLin Valerio Nobili Stefania Nori Marcello Persico Danièle Pariente Piotr Socha Sarah Ann Tizzard Pietro Vajro Raffaella Vecchione MD, Head of Gastroenterology unit, Medical Director of the liver transplantation program, University of Geneva, School of Medicine, Switzerland Secretary of the ESPGHAN Hepatology Committee MD, Head of Hepatometabolic Liver Disease Section, Chief of Liver Research Unit, Bambino Gesù Pediatric Hospital, Rome, Italy Vice-President of SIGENP (Italian Society Gastro Hepato Nutrition Pediatric) MD, Associate Professor of Human Anatomy, Department of Medicine and Surgery, University of Salerno, Baronissi (Sa), Italy MD, Associate Professor of Internal Medicine, Chief of Hepatology Section, Department of Medicine and Surgery, University of Salerno, Baronissi (Sa), Italy MD, Responsible of the Pediatric Radiology Department, Hospital Bicêtre, University Hospital Paris- Sud, Le Kremlin Bicêtre, France MD, PhD, Associated Professor, Gastroenterology Consultant, Department of Gastroenterology, Hepatology and Immunology, The Children's Memorial Health Institute, Warsaw, Poland RN, Paediatric Clinical Nurse Specialist for Viral Hepatitis, Pediatric Liver Transplantation Centre, King's College Hospital, London, UK MD, Associate Professor of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Medicine and Surgery, Faculty Delegate for the Erasmus Exchange Programme, University of Salerno, Baronissi (Sa), Italy MD, Professor of Pathological Anatomy, Faculty of Medicine and Surgery, University of Naples Federico II, Naples, Italy

PEDIATRIC HEPATOLOGY SUMMER SCHOOL organized by the ESPGHAN Hepatology Committee May 14-17, 2014 Vietri sul Mare (Salerno), Italy APPLICATION REQUEST Title Family name First name Institution/Hospital Department Street address Town Zip code Country Telephone 1 Telephone 2 Fax E-mail Documents to be attached: - Brief CV - List of publications - Letter of intent Application procedure The ESPGHAN Summer School is limited to a maximum of 40 pediatricians (specialists and non specialists). Applicants will have to complete the application form and send it to info@jeangilder.it, together with the requested documents. Applicants will be selected on the basis of their CV, of their publications, and of a letter of intent. Deadline for returning the application form is February, 28 2014. Participants will receive confirmation of their admission by March 15, 2014 and will have to complete the registration procedure, including payment, by April 13, 2014. Please return by 28 February 2014 via email to info@jeangilder.it Organizing Secretariat: Scientific Communication srl Via G. Quagliariello 29, 80131, Napoli Tel +39 081 2296460/6037, Fax +39 081 0072045; email: info@jeangilder.it www.jeangilder.it