FAMILY: MUM AND DAD 9 MONTHS OLD CLARA, BERTRAM 3 YEARS OLD BOTH HEALTHY

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FAMILY: MUM AND DAD 9 MONTHS OLD CLARA, BERTRAM 3 YEARS OLD BOTH HEALTHY Visiting Danish friends in Rio de Janeiro for 2-3 weeks, good living conditions. Going to The Amazonas, and to the beach.

CLARA 9 MONTH OLD PARENTS WILL LIKE TO GET HER VACCINATED Possibilities : Yellow fever? Hepatitis A? Hepatitis B? Dengue? Rabies? BCG? Rota? Typhoid? Measles? DiTeKiPol Act Hib? Others?

BERTRAM 3 YEARS OLD Possibilities : Yellow fever? Hepatitis A? Hepatitis B? Dengue? Rabies? BCG? Rota? Typhoid? Measles? DiTeKiPol Act Hib? Others?

YELLOW FEVER OUTBREAK Yellow fever outbreak Brazil over Epinyt uge 37-2017 Da der ikke har været rapporteret om gul feber-tilfælde siden juni 2017, har sundhedsministeriet i Brasilien pr. 7. september 2017 erklæret udbruddet for ovre. I udbruddet blev der fra december 2016 til 1. august 2017 rapporteret om 777 laboratoriebekræftede tilfælde. Flest tilfælde var fra den sydøstlige region med 764 tilfælde efterfulgt af 10 tilfælde fra den nordlige region og tre tilfælde fra den central-vestlige region i Brasilien.

Areas where vaccination is recommended against Yellow Fever Yellow Book 2017

CASE 2 - GOING TO BENIN FOR 2 YEARS Danish family : dad, mum and Sophie 4 years and Peter 2 months old Dad ingenieur Job station outside Porto-novo frequent travel to the area around Bante

PETER 2 MONTHS OLD BCG? DiTeKiPol-Act Hib Prevenar Hep B? Hep A /Twinrix? Yellow fever? Rabies? Typhoid? Measles? Rotavirus? Influenza? Meningococcal vaccine ACWY? B?

CHILDHOOD VACCINATION PROGRAMME 3 mdr. difteri-tetanus-kighoste-polio-hib 1- og PCV-1 5 mdr. 1 difteri-tetanus-kighoste-polio-hib 2 og PCV-2 12 mdr. 1 difteri-tetanus-kighoste-polio-hib 3 og PCV-3 15 mdr. MFR 1 4 år 1 MFR 2 5 år 1 difteri-tetanus-kighoste-polio revaccination 12 år 2 MFR 2 og til piger HPV 1, 2 4 Endvidere kan kvinder vaccineres gratis mod røde hunde 9

In the meningitis belt, serogroup A has historically accounted for 90% of meningococcal disease cases and the majority of large-scale epidemics.

MENINGOCOCCAL VACCINES The preferred vaccine for people aged 2 months through 55 years and meningococcal vaccine-nonnaïve people aged 56 years is MenACWY Nimenrix should be used in accordance with available official recommendations. SPC: Infants from 6 to 12 weeks of age The recommended immunisation series consists of three doses, each of 0.5 ml. The primary infant series consists of two doses, with the first dose given from 6 weeks of age and with an interval of 2 months between doses. The third (booster) dose is recommended at 12 months of age (see section 5.1). Children from 12 months of age, adolescents and adults A single 0.5 ml dose should be administered. A second dose of Nimenrix may be considered appropriate for some individuals Previously vaccinated children from 12 months of age, adolescents and adults Nimenrix may be given as a booster dose to individuals who have previously received primary vaccination with a conjugated or plain polysaccharide meningococcal vaccine Menveo: Children (from 2 years of age), adolescents and adults should be administered as a single dose (0.5 ml). Data for <2 years not available

GOING TO VIETNAM/CAMBODIA FOR 6 WEEKS Family: mum and dad one boy Jesper 4 years old healthy Travelling in Northern Cambodia and Central Highlands and Mekong Vietnam Basic accomodations

JESPER 4 YEARS FAMILY WILL LIKE TO GET HIM VACCINATED Recommendations Yellow fever? Dengue vaccination? Japanese Encephalitis? Hepatitis A? Hepatitis B? BCG? Typhoid? Measles? Rabies? DiTeKiPol Act Hib? Others?

TRAVELLING WITH CHILDREN Individualized advice: Destination Epidemiology Duration Living conditions Institution/school locally Animal contact

BØRNEVACCINATIONSPROGRAMMET 3 mdr. difteri-tetanus-kighoste-polio-hib 1- og PCV-1 5 mdr. 1 difteri-tetanus-kighoste-polio-hib 2 og PCV-2 12 mdr. 1 difteri-tetanus-kighoste-polio-hib 3 og PCV-3 15 mdr. MFR 1 4 år 1 MFR 2 5 år 1 difteri-tetanus-kighoste-polio revaccination 12 år 2 MFR 2 og til piger HPV 1, 2 4 Endvidere kan kvinder vaccineres gratis mod røde hunde 15

IMMUNIZATIONS Coverage of childhood immunizations DPT-Polio- Hib-Pnc-(hepB) (3-5-12 months), may be given at birth and subsequently at monthly doses MMR (15 months), may be given from 6 months BCG at birth or later

IMMUNIZATIONS Travel vaccines: Hepatitis A (above 2 years) Japanese Encephalitis (as DPT) Meningococcal A/C/Y/W135 (above 3 months) Rabies Ty21a (above 6 years) Typhim Vi (above 3 years)

IMMUNIZATIONS Travel vaccines: Rotavirus vaccine Oral cholera (above 2 years) Yellow fever(above 12 months (6)) Immunoglobulin (special situations)

TUBERCULOSIS Consider BCG vaccination In seroconverters below 5 years (-10) consider INH prophylaxis for 6 months A 1 year old converter has a 10% risk of TB disease over next 5 years without prophylaxis

OTHER RISKS Infections with resistant bacteria ( MRSA, gram negative organsims, MDR TB, Pneumococci) Leishmaniasis Rickettsioses