MedStar Health, Inc. POLICY AND PROCEDURE MANUAL

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MedStar Health, Inc. POLICY AND PROCEDURE MANUAL MP.049.MH Visually Evoked Response Test This policy applies to the following lines of business: MedStar Employee (Select) MedStar MA DSNP CSNP MedStar CareFirst PPO MedStar Health considers Visually Evoked Response (VER) Tests medically necessary for the following indications: VER testing for the following indications is covered when prescribed by Ophthalmologists and Neurologists. See Limitations Section below. Adults and children ages six months and older, who experience any of the following: Double or blurred vision Loss of part or all vision Eye injuries, head injuries To identify members at increased risk for developing Clinically Definite Multiple Sclerosis (CDMS) To diagnose and monitor multiple sclerosis (acute or chronic phases) To localize the cause of visual field defect not explained by MRIs, CT scans, metabolic disorders, or infectious diseases Limitations VER is not considered medically necessary for any the following: As a diagnostic vehicle for children under 6 months of age For members with severe nearsightedness For members with optic neuritis already diagnosed with abnormal VER latency This test will only be covered when requested/ordered by an Ophthalmologist or Neurologist. Background Visually Evoked Response (VER) is a painless test using the brain s electrical response to visual stimulus to detect optic neuritis or other demyelinating events along the optic nerves. VER measures the function of the visual pathway from the retina to the occipital cortex. This test can diagnose problems with the optic nerves that affect sight. VERs are more sensitive to slowed visual responses and can often identify dysfunction which is undetectable through clinical evaluation and when the member is unaware of

any visual defects. The VER test is often useful in providing additional information beyond an MRI. VER s have the ability to detect involvement of the visual pathway that may not always result in visual disturbance and serve as a complimentary diagnostic tool for certain demyelinating diseases. A standard VER test consists of three scalp electrodes over the occipital cortex measuring eye stimulation from an alternating black and white checkerboard pattern. The electrical response along the optic nerve is detected in the brain using an EEG. Completely non-invasive, the test is conducted in a dark room and may last several minutes. Factors that can affect VER include pupil size, gender and age. No medications are administered, and there is no preparation for, or recovery required following the test. There are no visual problems resulting from this test, and the member can resume a normal routine following the testing. Codes: CPT Codes / HCPCS Codes / ICD-10 Codes Code CPT Codes Description 95930 Visually evoked potential (VEP) testing central nervous system, checkerboard or flash ICD-9 codes covered if selection criteria are met: 036.81 Meningococcal optic neuritis 054.3 Herpetic meningoencephalitis 055.0 Postmeasles encephalitis 056.01 Encephalomyelitis due to rubella 058.21 Human herpesvirus 6 encephalitis 058.29 Other human herpesvirus encephalitis 062.0-064 Mosquito-borne viral encephalitis, tick-borne viral encephalitis, and viral encephalitis transmitted by other and unspecified arthropods 088.81 Lyme disease 094.0-094.9 Neurosyphilis 192.0-192.9 Malignant neoplasm of other and unspecified parts of nervous system 198.3-198.4 Secondary malignant neoplasm of brain and spinal cord 225.0-225.9 Benign neoplasm of brain and other parts of nervous system Page 2 of 7

237.0-237.1 Neoplasm of uncertain behavior of endocrine glands and nervous system 237.5-237.9 Neoplasm of uncertain behavior of brain and spinal cord, meninges, neurofibromatosis, and other and unspecified parts of nervous system 239.6 Neoplasm of unspecified nature of brain 300.11 Conversion disorder 324.0 Intracranial abscess 324.1 Intraspinal abscess 333.0 Other degenerative diseases of the basal ganglia 334.0-334.9 Spinocerebellar disease 340 Multiple sclerosis 341.0-341.9 Other demyelinating diseases of central nervous system 342.00-342.92 Hemiplegia and hemiparesis 343.0-343.9 Infantile cerebral palsy 348.1 Anoxic brain damage 348.2 Benign intracranial hypertension 348.4 Compression of brain 348.5 Cerebral edema 350.1-358.9 Trigeminal, facial, and other cranial nerve disorders, nerve root and plexus disorders, mononeuritis, neuropathy, and myoneural disorders 365.00-365.9 Glaucoma 369.00-369.9 Blindness and low vision 368. 00-368.9 Visual disturbances 377.00-377.9 Disorders of the optic nerve and visual pathways 386.00-386.9 Vertiginous syndromes and other disorders of vestibular system 388.00-389.9 Other disorders of ear and hearing loss 430-435.9 Subarachnoid hemorrhage, intracerebral hemorrhage, other and unspecified intracranial hemorrhage, occlusion and stenosis of precerebral arteries, occlusion of cerebral arteries, and transient cerebral ischemia 437.3 Cerebral aneurysm, nonruptured 756.0 Anomalies of skull and face bones Page 3 of 7

780.01-780.09 Alteration of consciousness 780.4 Dizziness and giddiness 781.2-781.4 Abnormality of gait, lack of coordination, and transient paralysis of limb 784.3 Aphasia [unable to communicate] 794.10-794.19 Nonspecific abnormal results of function studies of peripheral nervous system and special senses 850.4-853.19 Concussion with prolonged loss of consciousness without return to preexisting conscious level 907.1-907.5 Late effect of injury to cranial nerve, spinal cord, nerve root(s), spinal plexus(es), and other nerves of trunk, peripheral nerve of shoulder girdle and upper limb, or peripheral nerve of pelvic girdle and lower limb 950.0-950.9 Injury to optic nerve and pathways 957.0 Injury to superficial nerves of head and neck 957.1 Injury to other specified nerve(s) 957.8 Injury to multiple nerves in several parts 957.9 Injury to nerves, unspecified site ICD-10 codes covered if selection criteria are met: A39.82 Meningococcal retrobulbar neuritis B00.4 Herpesviral encephalitis B05.0 Measles complicated by encephalitis B06.01 Rubella encephalitis B10.01 Human herpesvirus 6 encephalitis B10.09 Other human herpesvirus encephalitis A52.11-A52.7 A69.20-A69.29 A83.0-A86 C70.0-C72.59 C79.31-C79.49 D32.0-D33.9 Neurosyphilis Lyme disease, other conditions associated with Lyme disease Unspecified viral encephalitis Malignant neoplasms of brain and other parts of central nervous system Secondary malignant neoplasm of brain, cerebral meninges, and other parts of nervous system Benign neoplasm of meninges, brain, and other parts of nervous system Page 4 of 7

D42.0-D44.9 Neoplasms of uncertain behavior of meninges, brain, central nervous system, and endocrine glands D49.6 Neoplasm of unspecified behavior of brain E03.5 Myxedema coma F44.4-F44.9 Conversion disorders G06.0 Intracranial abscess and granuloma G06.1 Intraspinal abscess and granuloma G11.0-G11.9 G23.0-G23.9 G35 G36.0-G37.9 G45.0-G45.9 G50.0-G59 G60.9 G63 G70.00 G80.0-G80.9 Hereditary ataxia Other degenerative diseases of basal ganglia Multiple sclerosis Other demyelinating disease of central nervous system Transient cerebral ischemic attacks and related symptoms Nerve, nerve root, and plexus disorders Hereditary and idiopathic neuropathy, unspecified Polyneuropathy in diseases classified elsewhere Myasthenia gravis without (acute) exacerbation Cerebral palsy G81.00 Flaccid hemiplegia, unspecified side G81.90-G81.94 Hemiplegia and hemiparesis G90.3 Multi-system degeneration of the autonomic nervous system G93.1 Anoxic brain damage, not elsewhere classified G93.2 Benign intracranial hypertension G93.5 Compression of brain G93.6 Cerebral edema H40.001-H42 H46.00-H47.9 H53.001-H53.9 H54.0-H54.8 H81.01-H82.9 H90.0-H94.83 Glaucoma Optic neuritis and other disorders of optic (2 nd ) nerve and visual pathways Visual disturbances Blindness and low vision Disorders of vestibular function and vertiginous syndromes in diseases classified elsewhere Other disorders of ear Page 5 of 7

I60.00-I69.998 Q75.0-Q75.9 R26.0-R29.91 R40.0-R40.4 R42 R47.01 Aphasia R94.0-R94.138 S04.011A- S04.019A S04.011S- S04.9XXS S06.0x9A S06.330A S14.0XXA- S14.9XXS S34.114S S44.00XA- S44.92XS S84.00XA- S84.92XS Cerebrovascular diseases Other congenital malformations of skull and face bones Abnormalities of gait and mobility, lack of coordination, and other symptoms and signs involving the nervous and musculoskeletal systems Somnolence, stupor, and coma Dizziness and giddiness Abnormal results of function tests central/peripheral nervous systems and senses Injury of optic nerve Injury of cranial nerve Concussion with loss of consciousness of unspecified duration, initial encounter Contusion and laceration of cerebrum, unspecified, with loss of consciousness of 1 hour to 5 hours 59 minutes, initial encounter Injury of nerves and spinal cord at neck level Complete lesion of L4 level of lumbar spincal cord Injury of nerves at shoulder and upper arm level Injury of nerves at lower leg level References 1. Centers for Medicare and Medicaid Services: National Coverage Determination (NCD) No. 160.10 - Evoked Response Tests. Issued January 15, 1980. http://www.cms.gov/medicare-coverage-database/details/ncddetails.aspx?ncdid=200&ncdver=1&bc=agaagaaaaaaaaa%3d%3d& 2. Evans AB; Medscape- Current Clinical Role of Evoked Potentials: Visual Evoked Potential. Updated 3/18/2014. http://emedicine.medscape.com/article/1137451- overview#aw2aab6b3 Page 6 of 7

3. Hayes Technology Assessment Report. Visual Evoked Potentials for Diagnosis/Prognosis of Multiple Sclerosis. Publication date: 03/01/2006. Revision date: 03:24/2010. 4. Sand T, Kvaløy MB, Wader T, et al. Evoked potential tests in clinical diagnosis. Tidsskr Nor Laegeforen. 2013 May 7;133(9):960-965. doi: 10.4045/tidsskr.12.1176. http://tidsskriftet.no/article/3011088/en_gb 5. Visually Evoked Responses Multiple Sclerosis Encyclopedia. http://www.multsclerosis.org/visuallyevokedresponse.html Disclaimer: MedStar Health medical payment and prior authorization policies do not constitute medical advice and are not intended to govern or otherwise influence the practice of medicine. The policies constitute only the reimbursement and coverage guidelines of MedStar Health and its affiliated managed care entities. Coverage for services varies for individual members in accordance with the terms and conditions of applicable Certificates of Coverage, Summary Plan Descriptions, or contracts with governing regulatory agencies. MedStar Health reserves the right to review and update the medical payment and prior authorization guidelines in its sole discretion. Notice of such changes, if necessary, shall be provided in accordance with the terms and conditions of provider agreements and any applicable laws or regulations. These policies are the proprietary information of Evolent Health. Any sale, copying, or dissemination of said policies is prohibited. Page 7 of 7