GPS Safety Summary (25 % solution in methyl methacrylate) The Product Safety Summary is intended to provide a general overview of the chemical substance in the context of ICCA Global Product Strategy. The information on the summary is basic information and is not intended to provide emergency response, medical or treatment information. Substance name CAS-No. 86261-90-7 General statement is used as an intermediate product for polymer synthesis in the chemical industry. Exposure to this chemical substance is very limited. Consumer risk and exposure is unlikely as N-(2- Methacryloxyethyl) ethylene urea is manufactured and handled in industrial settings only. The environmental effects, ecotoxicology and toxicology information available for is provided based on studies and/or a reliable evaluation of its hazardous properties. should not enter surface water, groundwater and soil. General and substance specific operational conditions and risk management measures are in place to prevent exposure to workers and release to the environment. Chemical identity Name Brand names VISIOMER MEEU 25M Chemical name (IUPAC) 2-Propenoic acid, 2-methyl-, 2-(2- oxo-1-imidazolidinyl)ethyl ester CAS number 86261-90-7 Molecular formula Structure C9H14N2O3 Synonyms Ethylene ureaethyl methacrylate Evonik Industries AG GPS Safety Summary December 2014 Version 1 page 1/6
Uses and application is used as an intermediate for the production of polymers in the chemical industry. Furthermore, it is commercially available as 25% solution in methyl methacrylate, where properties are strongly influenced by methyl methacrylate (see also GPS safety summary methyl methacrylate). Physical/chemical properties Property Physical state Color Odor Melting / boiling point Density Molecular weight Water solubility Vapor pressure Ignition temperature Flashpoint Octanol-water partition coefficient Viscosity Value Liquid (25% solution in methyl methacrylate) Yellowish Ester-like Not available / 100 C (start of boiling) 1.0 g/ml (20 C) 198.22 g/mol Miscible Ca. 40 hpa (20 C) (methyl methacrylate) 430 C (methyl methacrylate) 10 C (DIN 51755) (methyl methacrylate) log Pow: 1.13 (N-(2-methacryloxyethyl) ethylene urea) 1.0 mpa s (20 C) Health effects Effect Assessment Acute toxicity (oral) Eye / Skin irritation Sensitization Genotoxicity/mutagenicity Teratogenicity Result Low toxicity. Contact with skin may cause irritations. Causes serious eye damage. Sensitizing by skin contact. No evidence for respiratory sensitization. No evidence of mutagenic/genotoxic effects. No evidence of developmental toxicity Evonik Industries AG GPS Safety Summary December 2014 Version 1 page 2/6
Environmental effects Effect Assessment Aquatic toxicity (acute/ shortterm) Result Low toxicity to water organisms. Fate and Behavior Biodegradation Bioaccumulation potential PBT / vpvb conclusion Result Readily biodegradable (methyl methacrylate); Readily biodegradable, 10-day window not reached (N-(2- Methacryloxyethyl) ethylene urea) Significant accumulation not expected. Neither considered to be PBT nor vpvb. Exposure Human health Exposure is not likely to occur in a manufacturing or formulation facility as it is used in a closed process with limited exposure. Each facility should have a thorough training program for employees and appropriate work processes and safety equipment in place to limit unnecessary exposure. Workers should follow the recommended safety measures in the Safety Data Sheet (SDS). Consumers will not come in contact with N-(2-Methacryloxyethyl) ethylene urea. Environment is manufactured and used in the chemical industry in closed systems; therefore, no release to the environment is expected. Direct use by consumers is not intended. Risk management recommendations Industry use, production and formulation An Occupational Industrial Hygiene Program is implemented. Proper personal protective equipment if applicable for respiratory, hand, eye, skin and body protection should be available. Provide employee training to prevent / minimize exposures and report all incidents involving the health and safety of personnel. Emissions are minimized through appropriate technical measures. No direct release to soil, surface water and groundwater. Consumer use Direct use by consumers is not intended. State agency review UN-GHS Ver. 4 (2011) Evonik Industries AG GPS Safety Summary December 2014 Version 1 page 3/6
Regulatory information/classification and labelling GHS-Classification Statutory basis UN-GHS Ver. 4 (2011) (25 % solution in methyl methacrylate) Flammable liquid Hazard category 2 Caustic burning / irritation of Hazard category 2 skin Skin sensitizer Hazard category 1B Serious eye damage /eye Hazard category 1 irritation STOT single exposure Hazard category 3 (respiratory tract) Hazardous to the aquatic Hazard category 3* environment Acute Hazard GHS-Labelling Statutory basis UN-GHS Ver. 4 (2011) Symbol(s) (25 % solution in methyl methacrylate) Signal word Hazard statement Precautionary statements Prevention Reaction Danger H225 - Highly Flammable liquid and vapor. H315 - Causes skin irritation. H317 - May cause an allergic skin reaction. H318 Causes serious eye damage. H335 - May cause respiratory irritation. H402 - Harmful to aquatic life. Precautionary statements and more information about N-(2- Methacryloxyethyl) ethylene urea can be found on the Safety Data Sheet. P280 - Wear protective gloves/ protective clothing/eye protection/face protection. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue * No worldwide use of this category. Not used in the European Union. Evonik Industries AG GPS Safety Summary December 2014 Version 1 page 4/6
Disposal rinsing. Immediately call a POISON CENTER / doctor. (P310) P301 + P312 If swallowed: Call a Poison Center or doctor/physician if you feel unwell. P302 + P352 IF ON SKIN: wash with plenty of soap and water. IF INHALED: Remove person to fresh air and keep comfortable for breathing. (P304 + P340) P501 Dispose of contents/container in accordance with local regulation. Evonik Industries AG GPS Safety Summary December 2014 Version 1 page 5/6
Glossary Acute toxicity Biodegradable Bioaccumulation Carcinogenicity Chronic toxicity GHS Mutagenicity PBT Reprotoxicity Sensitizing Teratogenic vpvb harmful effects after a single exposure breakdown of materials by a physiological environment accumulation of substances in the environment effects causing cancer harmful effects after repeated exposures Global Harmonized System on Classification and Labeling effects that change genes Persistent Bioaccumulative Toxic teratogenicity, embryotoxicity and harmful effects on fertility allergenic effects on foetal morphology very Persistent very Bioaccumulative Contact information within company Email address EU cmda@evonik.com Email address USA product.regulatory.services@evonik.com For more product safety summaries, please visit: Methacrylates Producers Association This GPS Safety Summary is based on Evonik s present knowledge and experience as of the date of issue. However, it implies no liability or other legal responsibility on the part of Evonik, including with regards to existing third party intellectual property rights, especially patent rights. In no event shall Evonik be responsible for damages of any nature whatsoever resulting from the use of or reliance upon the information herein or the chemical to which that information refers. In particular, no warranty, whether express or implied, or guarantee in the legal sense is intended or implied by Evonik. This GPS Safety Summary is only intended to provide general information about the chemical referred to herein but not any in-depth health and safety information. The information in this GPS Safety Summary is supplied on the condition that the persons receiving the same will make their own determination as to its suitability for their purposes prior to use. This GPS Safety Summary does not supersede or replace required regulatory and/or legal communication documents. Performance of the chemical described herein should be verified by testing which should be carried out only by qualified experts. Evonik reserves the right to make any changes to this GPS Safety Summary in accordance with technological progress or further developments. Reference to trade names used by other companies is neither a recommendation, nor does it imply, that similar products could not be used. December 2014