Date of Meeting: Ratified Date: 03/06/2009

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Document Type: PROTOCOL Title: Management And Transfer Of Patients With Acute Scope: Cardiac Network-wide Author/Originator and Title: Dr Ranjit More & members of the Cardiac Network Clinical Advisory Group Unique Identifier: CORP/PROT/010 Version Number: 4 Status: Ratified Classification: Organisational Responsibility: Cardiac Network Replaces: CORP/PROT/010 VERSION 3 Management And Transfer Of Patients With Acute Description of amendments: Amended throughout the document Name of Committee: Divisional/Directorate/ Working Group: Cardiac and Stroke Networks in Lancashire & Cumbria Cardiac Network Clinical Advisory Group Pharmacy check Date of Meeting: 11.3.09 03/06/2009 Validated by: Sally Chisholm, Cardiac and Stroke Networks Programme Director Risk Assessment: Not Applicable Financial Implications Not Applicable Validation Date: 11.3.09 Ratified by: Clinical Improvement Committee Chairman s Action Review Dates: Review dates may alter if any significant changes are made Ratified Date: 03/06/2009 Date of Issue: 04/06/2009 Review Date: 01/06/2011 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Does this document meet with the Race Relation Amendment Act (2000) Religious Discrimination Act, Age Discrimination Act, Disability Discrimination Act and Gender Equality Regulations? Not Applicable

1 PURPOSE. To improve the care pathway and transfer of patients presenting with Acute Coronary Syndrome (ACS) within Lancashire and South Cumbria. 2 SCOPE. This protocol applies to all medical staff both referring and treatment centres across Lancashire and South Cumbria and implemented by Cardiac Network 3 PROTOCOL (Excludes ST elevation/left Bundle Branch Block (LBBB)) 3.1 HIGH RISK: URGENT INVASIVE ASSESSMENT: PATIENTS TO BE TRANSFERRED AS AN EMERGENCY TO THE TERTIARY CENTRE (TRANSFER TIME <24 HOURS) The following criteria are agreed: 3.1.1 Patients who are experiencing recurrent chest pain despite medical therapy (including intravenous (IV) nitrates) with ST depression of >1 mm in at least two leads (i) (ii) These patients should be discussed for urgent transfer and angiography. Ensure clopidogrel is given and consider the use of iv Glycoprotein IIb/IIIa inhibitors. Patients should be discussed with a Consultant Physician/Cardiologist at the DGH prior to the on call registrar liaising with the Tertiary Centre. The electronic whiteboard, Algorithm (Appendix 1) and Transport guidelines for all cardiac transfers between District General Hospitals (DGHs) and Tertiary Centre (Lancashire Cardiac Centre, LCC) (Appendix 2) should be used for all patients 3.1.2 Patients who are experiencing refractory chest pain despite medical therapy (including intravenous (IV) nitrates) 3.1.3 Patients with haemodynamic instability or heart failure 3.1.4 Patients with life threatening arrhythmias (VF/VT) 3.2 EARLY INVASIVE ASSESSMENT: PATIENTS WITH CHEST PAIN TO BE TRANSFERRED AS AN URGENT CASE TO THE TERTIARY CENTRE (TRANSFER TIME <72 HOURS) 3.2.1 Patients with elevated troponin (I or T) levels 3.2.2 Patients with dynamic ST/T wave changes 3.2.3 Early post MI angina 3.2.4 Recent PCI (<6/12) - if chest pain is considered to be highly suspicious for myocardial ischaemia 3.2.5 Intermediate/high risk according to GRACE or TIMI score Page 2 of 5

3.3 ELECTIVE ASSESSMENT: PATIENTS WHO CAN BE STABILISED AND ASSESSED AT THE DISTRICT GENERAL HOSPITAL. THESE PATIENTS SHOULD BE INVESTIGATED LOCALLY (E.G. BY NON-INVASIVE IMAGING) 3.3.1 Patients with intermittent ongoing chest pain unaccompanied by ECG changes and normal troponin levels 3.3.2 Patients with no recurrence of pain and normal ECG and troponin levels 3.4 PATIENTS WITH CO-MORBIDITY Angiography may need to be delayed in the following circumstances Recent Cerebro Vascular Accident (CVA) within six weeks Haemoglobin (HB) drop of > 2g/dl during same admission Renal failure (Creatinine >200) Significant general frailty Significant other Comorbidity e.g. Chronic Obstructive Pulmonary Disease (COPD)/acute infection 3.5 PROCEDURES TO BE COMPLETED PRIOR TO INVESTIGATION FOR NON-EMERGENCY PATIENTS Ensure patient is informed of the potential procedures that they may undergo (arrange viewing of Heart to Heart video if possible) Treat any confounding issues that may influence the decision to catheterise or revascularise Consultant Cardiologist at the referring centre should be consulted, in particular if there are any complicating issues, before referral Methicillin-Resistant Staphylococcus Aureus (MRSA) status to be checked in all patients, although this should not delay transfer of high risk patients Additional points: (i) (ii) At present there is not an agreed policy across the Network and indeed there is no agreed policy nationally either regarding choice of Troponin assay. It would be helpful if referring to LCC, doctors indicate their hospital s normal upper limits to doctors at LCC taking referrals. There is a formal Bed Management Protocol arranged between the Tertiary Centre and all District General Hospitals to accommodate these proposals. 3.6 DOCUMENTS REQUIRED TO ACCOMPANY THE PATIENT: Inpatient notes (or copies) including ECGs Patient s local notes Page 3 of 5

3.7 DRUG ISSUES 3.7.1 Glycoprotein IIb/IIIa Inhibitors should only be started under the direction of a Consultant Cardiologist or as part of an agreed protocol with the Cardiologists. The use of the specific IIb/IIIa inhibitor should be decided locally. If intermittent ongoing chest pain accompanied by new or transient ECG changes, and with raised troponins consider Glycoprotein IIb/IIIa inhibitor as well as clopidogrel. If the patient is receiving a IIb/IIIa inhibitor other than Reopro, the patient should be sent with a sufficient supply of the drug they are receiving to cover the journey to LCC. Once the patient has arrived at LCC, they will be clinically assessed and a decision made whether to discontinue the IIb/IIIa inhibitor or change the patient s current treatment to Reopro. 3.7.2 Warfarin All patients on therapeutic doses of Warfarin should have their International Normalised Ratio (INR) checked urgently and the result communicated to the accepting doctor at LCC. The issue of combining dual anti-platelet therapy to patients already taking Warfarin should be discussed with a Consultant Cardiologist. 3.8 CARDIOLOGY REVIEW All patients with a diagnosis of ACS syndrome should be seen by the local cardiology team within 24hours 3.9 CONTACT WITH LCC Out of hours or urgent/emergency transfers contact on-call Cardiology SpR Early transfers during daytime hours contact the Transfer Coordinator and complete patient details on the electronic whiteboard Please record the patient s GRACE/TIMI score in the referral notes Patients can be tracked by electronic whiteboard 3.10 VALUE OF ECHO In ACS patients echocardiography provides very useful information on LV function and concomitant valve disease and should ideally be performed prior to transfer this however may not be feasible in many of the high risk urgent invasive assessment category patients. 3.11 TROPONIN ELEVATIONS Elevated troponins should be in the context of chest pain suggestive of myocardial ischaemia for a diagnosis of ACS to be made mild elevations in troponin levels in the context of arrhythmias such as fast AF in the absence of chest pain does not mean the patient has an ACS. 4. ATTACHMENTS. Appendix 1 ACS Protocol Algorithm Appendix 2 Transport Guidelines for all cardiac Transfers between DGH and Tertiary Centre (LCC) Page 4 of 5

5. ELECTRONIC AND MANUAL RECORDING OF INFORMATION. Database for Policies, Procedures, Protocols and Guidelines Archive/Policy Co-ordinators office Blackpool Fylde & Wyre Hospitals NHS Trust Archived at the Cardiac and Stroke Networks Office. Room 176, Preston Business Centre, Watling Street Road, Fulwood, Preston, PR2 8DY or via the Cardiac Network website www.csnlc.nhs.uk 6. LOCATIONS THIS DOCUMENT ISSUED TO. Copy No Location Date Issued 1 Blackpool, Fylde and Wyre Hospitals NHS Trust. 04/06/2009 2 University Hospitals of Morecambe Bay NHS 04/06/2009 Trust. 3 East Lancashire Hospitals NHS Trust. 04/06/2009 4 Lancashire Teaching Hospitals NHS Foundation 04/06/2009 Trust. 5 Blackpool, Fylde and Wyre Hospitals NHS Trust. Document Library 04/06/2009 7. OTHER RELEVANT /ASSOCIATED DOCUMENTS. Procedure No. Title Operational Policy Repatriation Policy 8. AUTHOR//DIVISIONAL/DIRECTORATE MANAGER APPROVAL. Issued By Dr Ranjit More Checked By Sally Chisholm Job Title Signature Consultant Cardiologist/ Network Clinical Lead Job Title Signature Cardiac and Stroke Networks Programme Director Date May 2009 Date May 2009 Page 5 of 5

Appendix 1 Cardiac and Stroke Networks in Lancashire and Cumbria Acute Treatment Algorithm 2009-2010 Chest Pain>15mins/suspected ACS excluding ST elevation/lbbb Aspirin, Clopidogrel (Loading dose 300 mg 600 mg followed by 75 mg daily), Beta blockers, Low Molecular Weight Heparin (LMWH) or Fondaparinux 2.5 mg sc. High dose statin (standard); Ca channel blockers, Nicorandil, Nitrates (all optional) 12 hr (from pain) Troponin negative ECG Normal or transient ECG changes only 12 hr (from pain) Troponin positive ECG Abnormal 1. Ongoing Pain + Dynamic ST segment shift >2 leads 2. Chest pain and life threatening arrhythmias 3. Chest pain and haemodynamic instability Dynamic ST-T wave changes Early post MI angina Recent PCI (less than 6 months) Intermediate/high risk TIMI or GRACE score LOW RISK MEDIUM RISK HIGH RISK Stress test if appropriate Stop Clopidogrel Refer for inpatient angiography (transfer within 72 hours) Liaise with Tertiary Centre NO Suitable for Revascularisation? Consider IV GP llb/llla Re-discuss with Tertiary Centre if symptoms persist Consider IV GP llb/llla. Transfer within 24 hours NB Angiography may need to be delayed if a patient has significant co-morbidities (e.g. recent CVA, severe anaemia etc All patients with a diagnosis of ACS syndrome should be seen by the local cardiology team within 24 hours

Appendix 2 Puts on Ward 11 whiteboard TRANSPORT GUIDELINES FOR ALL CARDIAC TRANSFERS BETWEEN DGH AND TERTIARY CENTRE (Blackpool) BFWH SPR accepts patient by phone identifies type of transfer required AS1 AS2 CTV BFWH SPR checks CCU bed availability if Group 1 patient BFWH SPR informs Cardiac Pathway Co-ordinator (CPC) and asks for transfer to be arranged according to Protocol Confirms patient is on whiteboard ACS: GROUP 1 Emergencies <24hrs ACS: GROUP 2 Urgent transfers <1week ACS: GROUP 3 Delayed transfer until patient fit for procedure ACS: GROUP 4 Routine admission Office hours CPC contacts DGH and confirms bed availability. Out of Office Hours Delegated to CCU staff CPC confirms patient accepted by BFWH Admitted from home own transport or PTS CPC arranges transport via AS1/ 999/Ambulance control CPC contacts DGH link when bed available Patient taken direct to BFWH CCU. Confirms type of transport requirement unchanged Informs DGH that CTV to be used and expected time of collection LAS control will not accept any requests for booking of cardiac CTV transport. Advice will be given to contact the CPC. Crew will establish routing Patients In CPC contacts crew daily with detailed list of transfers in or out of BVH Patients Out Crew will confirm with ward expected time of arrival for collection and delivery CPC allocates patient to ward and informs CTV Destination outbound as agreed with CPC & DGH ITEMS FOR TRANSFER WITH PATIENT LOCAL NOTES LOCAL X-RAYS MOST RECENT BLOOD RESULTS CPC in contact via mobile phone for urgent changes with CTV Delegated to Ward 11 staff at BFWH for out of hours PATIENTS OWN AND HOSPITAL- PRESCRIBED MEDICATION AND AIDS E.G. DIABETIC PENS Following admission to BFWH, patient is assessed clinically and, if for angiogram, placed on whiteboard in Cath Lab Cardiac Pathway Co-ordinator will hand responsibility for transfers out of hours to: AS1 = CCU at BFWH CTV = Ward 11 staff Cardiac Transfer Vehicle crews will have the authority to refuse to carry inappropriate patients for their vehicle KEY LAS Lancashire Ambulance Service CPC Cardiac Pathway Co-ordinator CTV Cardiac Transfer Vehicle DGH District General Hospital Version2.2