EBMT EBMT Organisation and Activities J Apperley 13th. ESH-EBMT Training Course Targu Mures May 24 26, 2010 History Organisation Studies Activity Philosophy EBMT Website www.ebmt.org EBMT Society European Group for Blood and Marrow Transplantation Established in 1974 and registered in Maastricht Non-profit organisation that promotes excellence in haemopoietic cell transplantation including basic and clinical research, education, standardisation, quality control and accreditation of transplant procedures
EBMT Activity survey on HSCT 1973-2007 Allogeneic HSCT, autologous HSCT, Teams Membership Overview H S C T // Structure of EBMT Quality Manager EBMT Board Executive committee Working Parties Registries Patients and Families Nurses Group Committees JACIE Accreditation Programme Status: Acute Leukaemia Aplastic Anaemia Autoimmune Diseases National Activity Survey EBMT Working Parties Board Education Total Centers registered:206 Chronic Leukaemias Immunobiology Inborn Errors Infectious Diseases Late Effects Lymphoma Paediatric Diseases Solid Tumours Austria Czech Rep France Germany Italy -Allo Italy - Auto The Netherlands Central Registry Data Office, Paris Registry Support, London Inborn Errors Cord Blood Research committee Editorial Board Nuclear Accident Quality Assessment of HSC Grafts Developmental Prospective Clinical Trials Statistical Outreach Total inspections: 171 Facilities accredited: 139 Countries:16 Switzerland Turkey UK - BMT UK - paediatric 3563 members 527 centers 57 countries Cord Blood http://www.jacie.org/ close collaboration with FACT
EBMT Committees EBMT Educational Courses 2009 Cord Blood Education Nuclear Accident response Outreach Prospective Clinical Trials Quality assessment of autologous grafts Developmental Statistical Guidelines Regulations Visions Training Courses Handbook Dates Event Venue 25 28 May 2009 The 13th EBMT-ESH Training Course: Blood and Marrow Transplantation Latimer, UK 4-6 June 2009 2nd Training Course on Bone and Marrow Transplant in Children Genoa, Italy 17 20 Sept 2009 Joint EBMT Paediatric Working Party - Raisa Gorbacheva Third Memorial Meeting on Haematopoietic Stem Cell Transplantation Saint Petersburg, Russia 23 25 Sept 2009 EBMT Inborn Errors Working Party Meeting Cambridge, UK 16 17 Oct 2009 EBMT Acute Leukaemia Working Party Meeting and Symposium Barcelona, Spain 16 17 Oct 2009 EBMT Paediatric Diseases Working Party Meeting Barcelona, Spain 22 23 Oct 2009 5th EBMT Lymphoma Working Party Educational Course Haematopoietic Stem Cell Transplantation and Lymphoma Bristol, UK 29 31 Oct 2009 12th EBMT Infectious Diseases Working Party Training Course Rome, Italy 19 20 Nov 2009 Haematopoietic Stem Cell Transplantation (HSCT) for Severe Autoimmune Diseases Meeting Florence, Italy 27 29 Nov 2009 EBMT Immunobiology Working Party Meeting Perugia, Italy Data Management Group Network of transplant data managers and statisticians EBMT Central Registry Office, London EBMT Data Office, Paris PROMISE Data Capture System, Leiden EBMT Transplant Activity Survey Office, Basel Retrospective data analysis Med A Med B Med C Transplant Activty survey Outcome analysis Quality control EBMT ACTIVITY SURVEY Current status Indication Donor type Stem Cell Source Comparison Within region Between regions Population Economics Analysis Absolute numbers By population Trends Quality control instrument Policy tool Numbers
EBMT Activity survey on HSCT in 2008: patient and transplant numbers EBMT Activity survey on HSCT in 2008: main indications Indication Allogeneic HSCT Autologous HSCT Total Indication Allogeneic 1st Tx. Autologous 1 st Tx. Total 1st transplants 10782 16028 26810 Leukaemias* Lymphoproliferative 7632 1699 978 13428 8610 15127 Retransplants Additional transplants 861 102 890 1630 1751 1732 disorders Bone marrow failures Solid tumours Non-malignant disorders 615 62 699 2 1424 172 617 1486 869 TOTAL 11745 18548 30293 Others 75 26 101 Teams: 615 Countries: 42 2008: final data Total * includes CLL 10782 16028 26810 2008: final data EBMT risk score: Age, disease stage, donor type, 7me interval, gender combina7on Impact of JACIE accreditation status 1 0,8 0,6 0,4 0,2 0 1 0 1 2 3 4 5 6-7 AML ALL CML AA MDS MM NHL 0,8 0,6 0,4 0,2 0 AML ALL CML AA MDS MM NHL 0 1 2 3 4 Cancer 5 6-7 2009;115: 4715-4726 The European The European Group Group for Blood for Blood and Marrow and Marrow Transplantation
Scientific Activities of EBMT Networking WBMT Federation 46 Publications in peer-review journals 150 Retrospective Analyses underway 8 Prospective Clinical Trials underway 350,888 Transplants in the EBMT Registry 30,293 HSCTs submitted to the Activity Survey in 2009 3612 EBMT Members across 57 Countries