STEP THERAPY. Cigna Pharmacy Management. What is Step Therapy?

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STEP THERAPY Cigna Pharmacy Management What is Step Therapy? Prescription medications cost a lot of money. At Cigna, we get that. That s why we ve created a program that helps save you money and stay healthy. It s called Step Therapy. Step Therapy is a prior authorization program. This means that certain medications in the Step Therapy program need approval before they re covered. In Step Therapy, you and your doctor follow a series of steps when choosing your medication. You may be able to choose from several different safe and effective prescription medications to treat your condition. Cost is often the biggest difference. Generic medications which have the same strength and active ingredients as brand name medications typically cost less, while brand name medications are usually the most expensive. Cigna Pharmacy Management SM offers Step Therapy to treat several common medical conditions: ADD/ADHD Allergies Asthma Bladder problems Depression Heartburn/ulcer High blood pressure High cholesterol Mental health Osteoporosis Pain (narcotic and non-narcotic) Skin conditions Sleep disorders Step Therapy encourages you to try the most costeffective and appropriate medications available to treat your condition. Typically, these medications are generics or low-cost brands. You need to try these first, before more expensive medications are approved. When you fill a prescription for a Step Therapy medication, we ll send you and your doctor a letter explaining what steps you need to take before you refill your medication. This may include trying a generic or lower cost alternative, or asking Cigna for authorization for coverage of your medication. At any time, if your doctor feels a different medication isn t right for you due to medical reasons, he/she can request authorization for continued coverage of a Step Therapy medication. You can find Step Therapy medications on your prescription drug list. You can view the drug list on mycigna.com by clicking on the View Prescription Drug List link in the Pharmacy section. If ST is listed next to your medication name, then it s part of the Step Therapy program. Offered by: Connecticut General Life Insurance Company or Cigna Health and Life Insurance Company. 878402 c 06/16

ADD/ADHD & Stimulants amphetamine/dextroamphetamine (generic Adderall ) d-amphetamine (generic Dexedrine /Dextrostat ) dexmethylphenidate (generic Focalin ) methamphetamine (generic Desoxyn ) methylphenidate (generic Ritalin /Ritalin LA 20mg, 30mg, 40mg/ Ritalin SR /Metadate CD / Metadate ER /Concerta ) Allergy flunisolide (generic Nasarel ) fluticasone (generic Flonase ) triamcinolone acetonide nasal spray (generic Nasacort AQ ) Asthma & Respiratory albuterol (generic Accuneb ) albuterol sulfate levalbuterol (generic Xopenex ) Bladder Problems flavoxate (generic Urispas ) oxybutynin (generic Ditropan /Ditropan XL ) tolterodine (generic Detrol ) tolterodine LA (generic Detrol LA ) trospium (generic Sanctura /Sanctura XR ) Adderall XR (brand only) Focalin XR (brand only) Ritalin LA 10mg Vyvanse Nasonex Veramyst Detrol LA (brand only) Oxytrol Toviaz Vesicare Adderall (brand only) * Concerta (brand only) * Daytrana * Desoxyn (brand only) * Dexedrine (brand only) * Focalin (brand only) * Metadate CD (brand only) * Methylin * QuillivantTM XR * Ritalin /Ritalin LA 20mg, 30mg, 40mg/Ritalin SR (brand only) * ZenzediTM * Beconase AQ DymistaTM Flonase (brand only) Nasacort AQ (brand only) Omnaris QNASLTM Rhinocort Aqua ZetonnaTM Accuneb (brand only) Brovana Perforomist Stiolto Respimat*** Xopenex (brand only) Detrol (brand only) Ditropan XL (brand only) Enablex Gelnique MyrbetriqTM Sanctura (brand only) Sanctura XR (brand only) 2

Blood Pressure/Cardiovascular benazepril (generic Lotensin ) benazepril/hctz (generic Lotensin HCT ) candesartan (generic Atacand ) candesartan/hctz (generic Atacand HCT ) captopril (generic Capoten ) captopril/hctz (generic Capozide ) enalapril (generic Vasotec ) enalapril/hctz (generic Vaseretic ) eprosartan (generic Teveten ) fosinopril (generic Monopril ) fosinopril/hctz (generic Monopril HCT ) irbesartan (generic Avapro ) irbesartan/hctz (generic Avalide ) lisinopril (generic Prinivil /Zestril ) lisinopril/hctz (generic Prinzide /Zestoretic ) losartan (generic Cozaar ) losartan/hctz (generic Hyzaar ) moexipril (generic Univasc ) moexipril/hctz (generic Uniretic ) perindopril (generic Aceon ) quinapril (generic Accupril ) quinapril/hctz (generic Accuretic ) ramipril (generic Altace ) telmisartan (generic Micardis ) telmisartan/hctz (generic Micardis HCT ) trandolapril (generic Mavik ) valsartan/hctz (generic Diovan HCT ) Cholesterol Lowering atorvastatin (generic Lipitor ) lovastatin (generic Mevacor ) pravastatin (generic Pravachol ) simvastatin (generic Zocor ) Benicar Benicar HCT Diovan Diovan HCT (brand only) Crestor 5mg, 10mg Accupril (brand only) Accuretic (brand only) Aceon (brand only) Altace (brand only) Atacand (brand only) Atacand HCT (brand only) Avalide (brand only) Avapro (brand only) Cozaar (brand only) EdarbiTM EdarbyclorTM Hyzaar (brand only) Lotensin (brand only) Lotensin HCT (brand only) Mavik (brand only) Micardis (brand only) Micardis HCT (brand only) Monopril (brand only) Monopril HCT (brand only) Prinivil /Zestril (brand only) Prinzide /Zestoretic (brand only) Savaysa*** Teveten (brand only) Teveten HCT Uniretic (brand only) Univasc (brand only) Vaseretic (brand only) Vasotec (brand only) Altoprev Lipitor (brand only) LiptruzetTM Livalo Mevacor (brand only) Pravachol (brand only) Vytorin Zocor (brand only) 3

Depression bupropion (generic Wellbutrin /Wellbutrin SR / Wellbutrin XL ) citalopram (generic Celexa ) duloxetine (generic Cymbalta ) escitalopram (generic Lexapro ) fluoxetine (generic Prozac /Prozac Weekly / Sarafem / Rapiflux ) fluvoxamine paroxetine (generic Paxil /Paxil CR ) sertraline (generic Zoloft ) venlafaxine (generic Effexor /Effexor XR ) Mental Health clozapine (generic Clozaril ) clozapine ODT 12.5mg, 25mg, 100mg, (generic Fazaclo ) olanzapine/olanzapine ODT (generic Zyprexa /Zyprexa Zydis ) quetiapine (generic Seroquel ) risperidone (generic Risperdal /Risperdal M ) risperidone ODT ziprasidone (generic Geodon ) Osteoporosis alendronate (generic Fosamax ) ibandronate (generic Boniva ) Pristiq Wellbutrin XL (brand only) Seroquel XR Aplenzin * BrintellixTM * Celexa (brand only) * Cymbalta (brand only) * Desvenlafaxine Extended-Release * Effexor (brand only) * Effexor XR (brand only) * FetzimaTM * ForfivoTM XL * KhedezlaTM * Lexapro (brand only) * Paxil /Paxil CR (brand only) * Pexeva * Prozac (brand only) * Prozac Weekly (brand only) * Sarafem (brand only) * Venlafaxine ER * ViibrydTM * Wellbutrin (brand only) * Wellbutrin SR (brand only) * Zoloft (brand only) * Clozaril (brand only) Fanapt Fazaclo (brand only) Geodon (brand only) Invega Latuda Risperdal /Risperdal M (brand only) Saphris Seroquel (brand only) VersaclozTM Zyprexa /Zyprexa Zydis (brand only) Actonel Atelvia BinostoTM Boniva (brand only) Fosamax (brand only) Fosamax Plus D Skelid 4

Pain Relief (Narcotics) butorphanol codeine codeine phos/carisoprodol/asa dhcodeine bt/acetaminophen/caff dihydrocodeine/asa/caffeine hydrocodone w/acetaminophen (generic Lortab /Lorcet /Lorcet Plus /Norco / Vicodin /Vicodin ES /Vicodin HP /Xodol ) hydromorphone (generic Dilaudid ) ibuprofen/hydrocod (generic Vicoprofen ) levorphanol tartrate meperidine (generic Demerol ) morphine sulfate (generic MSIR /Roxanol ) opium tincture opium/belladonna alkaloids (generic B and O Supprettes ) oxycodone (generic OxectaTM/Roxicodone ) oxycodone w/acetaminophen (generic Percocet /Tylox /Primlev /Xolox ) pentazocine-acetaminophen pentazocine-naloxone tramadol (generic Ryzolt /Ultram /Ultram ER ) tramadol w/acetaminophen (generic Ultracet ) Pain Relief (NSAIDs) diclofenac (generic Voltaren /Voltaren-XR / Cataflam ) diclofenac/misoprostol (generic Arthrotec ) etodolac (generic Lodine /Lodine XL ) fenoprofen calcium flurbiprofen (generic Ansaid ) ibuprofen (generic Motrin ) indomethacin (generic Indocin /Indocin SR ) ketoprofen (generic Oruvail ) meclofenamate sodium mefenamic acid (generic Ponstel ) meloxicam (generic Mobic ) nabumetone naproxen (generic Naprosyn /EC-Naprosyn / Anaprox ) Lortab Solution (brand only) Roxicet ConZipTM Demerol (brand only) Dilaudid (brand only) Hycet Lorcet /Lorcet Plus (brand only) Lortab (brand only) Magnacet Maxidone Norco (brand only) OxectaTM Percocet (brand only) Percodan (brand only) Primlev (brand only) Roxicodone (brand only) Synalgos-DC (brand only) Ultracet (brand only) Ultram /Ultram ER (brand only) Vicodin /Vicodin ES / Vicodin HP (brand only) Vicoprofen (brand only) Xodol (brand only) Zamicet Zolvit Zydone Anaprox (brand only) Ansaid (brand only) Arthrotec (brand only) Cambia Cataflam (brand only) Celebrex Clinoril (brand only) Daypro (brand only) Feldene (brand only) Flector Indocin Oral Susp Indocin Suppos Mobic (brand only) Motrin (brand only) Nalfon 5

Pain Relief (NSAIDs) (continued) oxaprozin (generic Daypro ) piroxicam (generic Feldene ) sulindac (generic Clinoril ) tolmetin (generic Tolectin /Tolectin DS ) Skin Conditions alclometasone (generic Aclovate ) amcinonide ApexiCon E betamethasone (generic Diprosone /Diprolene / Diprolene AF /Valisone ) clobetasol (generic Clobex Shampoo & Lotion/ Olux /Temovate ) desonide (generic Tridesilon /Desowen ) desoximetasone (generic Topicort /Topicort LP ) diflorasone (generic ApexiCon ) fluocinolone (generic SynalarTM) fluocinonide (generic Lidex ) fluticasone (generic Cutivate ) Halac/Halonate PAC (generic Ultravate PAC combo oint/lot) halobetasol (generic Ultravate ) hydrocortisone (generic Lacticare-HC /Nuzon / Carmol HC /Locoid /Westcort /Ala-Scalp HP ) mometasone (generic Elocon ) prednicarbate (generic Dermatop ) triamcinolone (generic Kenalog ) Capex Shampoo Cloderm Cordran /Cordran SP Derma-Smoothe/FS Kenalog aerosol Nucort Texacort Naprelan Naprosyn /EC-Naprosyn (brand only) Ponstel (brand only) Voltaren /Voltaren-XR (brand only) Voltaren Gel Zipsor ZorvolexTM Aclovate (brand only) Ala-Scalp HP (brand only) Aqua Glycolic HC Carmol HC (brand only) Clobex (brand only) Cutivate (brand only) DermasorbTM HC/ DermasorbTM TA Dermatop (brand only) Desonate Desowen (brand only) Diprolene /Diprolene AF (brand only) Elidel Elocon (brand only) First Hydrocortisone Halog Kenalog (brand only) Locoid (brand only) Luxiq Momexin Olux /Olux-E (brand only) Pandel Pediaderm HC/TA Protopic Scalacort DK Synalar (brand only) Temovate (brand only) Topicort /Topicort LP (brand only) Ultravate /Ultravate PAC / Ultravate X (brand only) Vanos Verdeso Westcort (brand only) 6

Sleep Disorders eszopiclone (generic Lunesta ) zaleplon (generic Sonata ) zolpidem (generic Ambien ) zolpidem ER (generic Ambien CR ) Stomach Acid lansoprazole (generic Prevacid ) omeprazole (generic Prilosec ) omeprazole/sod bicarb 20mg, 40mg capsules (generic Zegerid ) pantoprazole (generic Protonix ) rabeprazole (generic Aciphex ) Silenor Dexilant Ambien (brand only) Ambien CR (brand only) Belsorma*** Edluar Intermezzo Lunesta (brand only) Rozerem Sonata (brand only) ZolpiMistTM Aciphex (brand only) esomeprazole strontium Nexium Prevacid (brand only) Prilosec (brand only) Protonix (brand only) Cigna and the Tree of Life logo are registered service marks, and Cigna Pharmacy Management is a service mark, of Cigna Intellectual Property, Inc., licensed for use by Cigna Corporation and its operating subsidiaries. All products and services are provided by or through such operating subsidiaries, including Connecticut General Life Insurance Company and Cigna Health and Life Insurance Company, and not by Cigna Corporation. 878402 c 06/16 2016 Cigna. Some content provided under license.