Self-Injected Medications and Disposal Recommendations

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Actimmune (interferon gamma 1b) Apokyn (apomorphine hydrochloride) Arixtra (fondaparinux) Avonex (interferon beta 1a) Betaseron (interferon beta 1b) Copaxone (glatiramer acetate) Edex (alprostadil) InterMune -chronic 3 per week granulomatous (injections disease TIW) -malignant osteopetrosis Mylan Bertek Parkinsons 500 Up to 7 per week (Daily PRN injections) GlaxoSmithKline DVT prophylaxis and treatment 7 per week (QD injections) Biogen Idec. MS 46,000 1 per week (weekly injections) Berlex MS 32,800 3-4 per week (QOD dosing) TEVA Pharmaceut. Industries Ltd. (shared solutions (TEVA neuroscience INC) MS 30,000 7 per week (QD dosing) Schwarz Pharma Erectile dysfunction 0-3 per week (MAX 3 per week) Sharps container, not published when full take to doctor s office or local fire department Sharps container not trash, not published, but call local health dept for locations to take container Dispose syringe into sharps container. Specially designed syringes to prevent needle sticks. State/local laws, check with healthcare professional for where to take container, do not throw in trash or recycle, keep out of reach of children Sharps or hard plastic or metal with lid, label used syringes. Not glass or clear plastic. Contact healthcare professional for where to take container. Do not throw in trash or recycle. Keep out of reach of children. Not on web site. Use sharps container, then call county health department or doctor s office for disposal. Contact doctor or pharmacist on where to obtain a proper discard container. Follow directions on container for disposal of container. 1

Caverject Pfizer Place in approved container. Called and product specialist said they have no specific recommendations or policy to tell Enbrel (entanercept) EpiPen (Jr) (epinephrine) Epogen (epoetin alpha) Forteo (teriparatide) Fragmin (daltaparin) Fuzeon (enfuvirtide) Amgen and Wyeth pharmaceuticals Dey RA, juevenal RA, psoraitic RA, ankylosing spondylitis, severe plaques psoriasis Anaphylaxis reactions 12,000 1-2 per week (QW or BIW dosing) Variable Amgen Anemia 3 per week (TIW dosing) Lilly Osteoporosis in 14,000 7 per week women and primary (QD dosing) or hypogonadal osteoporosis in men Pfizer DVT prophylaxis 7-14 per week (QD or BID dosing) Roche HIV-1 14 per week (BID dosing) Puncture-resistant container should be used for disposal. Sharps container offered through Enliven Services, call them for disposal locations. Used: take to ER and give to doctor. Expired: take to doctor s office for disposal or use your own sharps container. Place in container given by dialysis center, return full container to them. Place in puncture-resistant container, and dispose of container as directed by healthcare professional. Place in approved container. Called and product specialist said they have no specific recommendations or policy to tell Place directly into sharps container, do not overfill sharps and never throw sharps container in trash. Contact healthcare provider or pharmacy for ways to dispose of sharps. Keep sharps out of reach of children. Glucogon Beford hypoglycemia Variable No patient information online, not dispensed in an orange box Novo Nordisk Put everything back in orange box and dispose of properly Genotropin Pfizer growth hormone 18,400 6-7 per week (weekly dose divided into 6-7 doses) Place in approved container. Called and product specialist said they have no specific recommendations or policy to tell. 2

Humatrope Norditropin Nutropin Nutropin AQ Serostim (AIDS) Dihydroergotami ne (Generic) Lilly 9,200 Nordicare of Novo Nordisk Genetech 3,600 8,000 3 or 6 per week (weekly dose given QOD or QD for 6 days) 6-7 per week (weekly dosing in 6 or 7 doses) 7 per week (weekly dose divided into daily injections) serono 14 per week (dosed daily; need 2 needles: 1 for reconstitution, 6,000 another for injection) Paddock Labs Migraines 0-6 per week (1 ml delivery max; 6 ml per week) Place in puncture-resistant container and dispose of container as directed by healthcare professional. A puncture-resistant container should be recommended to dispose of used needles. Thoroughly instruct and caregivers on the importance of proper disposal of needle. Caution against any reuse of needles should be given. To ensure safety, it is important to correctly dispose of plastic needle guards* and used needles and syringes after you have given an injection. Your state may have special regulations about what kind of containers can be used for needle disposal. Check with your healthcare provider or pharmacist for instructions on the proper disposal of used needles and syringes. Safely dispose of the plastic needle guard* and all used needles and syringes after a single use. Always store your disposal container out of the reach of children. This product does not come with needles, but they do address disposing of the needles they use in a disposal box. The instruction pictures depict a box with a slot on top, like a piggy bank. The box has a lock on it and is labeled biohazard. Ampule only, no needle dispensed with product. 3

Humira (adalimumab) Imitrex (sumatriptan) Infergen (interferon alfacon-1) Innohep (Tizanaparin) LMWH Intron A (interferion alpha-2b) Abbott RA 8,000 0-1 per week (dosed QOW) GlaxoSmithKline Migraine or cluster headaches 0-14 per week (max dose 2 injections per day) InterMune Hep-C 3 per week (TIW dosing) LEO/ Pharmion DVT w/ or w/o PE 7 per week (daily dosing) Schering Plough Corp. Cancers AIDS 3,200 Depends on disease state and administration, not all indications allow for self injected Container designed for disposal or hard plastic with lid or metal with plastic lid. Label used syringes. Ask healthcare provider where to dispose of container. Needle in cartridge specially designed and disposable. Sharps container or hard plastic with lid or metal with plastic lid. Ask health professional where to dispose of container, do not throw away or recycle container. Keep out of reach of children. No patient instructions on website. Web: follow procedure for proper disposal of needles and syringes. In Product Info guide, the med should be dispensed with a container for disposal and needle safety information. Contact healthcare provider or garbage company for disposal of container. Kineret (anakinra) Amgen RA 4,000 7 per week (daily SC dosing) The syringes should NEVER be reused. NEVER recap a needle. Place the used syringe in a puncture-resistant container. A coffee can with a plastic lid or a hard plastic container with a screw-on top may be used. Puncture-resistant containers can also be purchased at your local pharmacy. Talk to your healthcare provider or pharmacist 4

Lovenox (enoxaparin) Neulasta (pegfilgrastin) Aventis Anticoagulant for prophalyxis and treatment of DVT w/ or w/o PE 7-14 per week (dosed QD or BID) Amgen Neutropenia 1 per week, and not every week (one dose every chemo cycle) about how to properly dispose of your used syringes. There may be special local and state laws for disposing of used needles and syringes. Do not throw the disposal container in the household trash. Do not recycle. The needle cover, alcohol swabs, and other used supplies can be placed in the trash. Always keep all syringes, injection supplies, and disposal containers out of the reach of children. Safety mechanism once syringe is used. Immediately dispose of the syringe into a sharps container. Disposal of prefilled syringes and needle guards*: One should always follow the instructions given by your doctor, nurse, or pharmacist on how to properly dispose of containers with used syringes and needle guards*. There may be special state and local laws for disposal of used needles and syringes. Do not throw the container in the household trash. Do not recycle. DO NOT put the needle cover (the cap) back on the needle. Place all used needle covers and syringes in a hard-plastic container with a screw-on cap, or a metal container with a plastic lid, such as a coffee can labeled "used syringes". If a metal container is used, cut a small hole in the plastic lid and tape the lid to the metal container. If a hard-plastic container is used, always screw the cap on tightly after each use. 5

Pegasys (peginterferon alpha 2a) Peg-Intron (peginterferon alpha 2b) Raptiva (efalizumab) Rebif (interferon beta 1a) Repronex (menotropins) Roche Hep C 23,200 1 per week (dosed weekly for max of 48 weeks) Schering Corporation Hep C 23,200 1 per week (dosed weekly for up to 1 year) Genentech, Inc. psoriasis 19,000 7 per week (dosing weekly) Serono, Inc. Pfizer, Inc. Ferring pharmaceuticals MS 2,400 3 per week (dosed TIW, at least 48 hours apart) Infertility 7 per week (daily doses) Do not use glass or clear plastic containers. When the container is full, tape around the cap or lid to make sure the cap or lid does not come off. Always keep the container out of the reach of children. Check with your health care provider for proper state and local disposal regulations. Place used syringes in sharps or other puncture-proof container. Do not use glass or clear plastic containers. Do not recycle or throw away in household trash. After preparation and administration of the PEG-Intron for injection, it is essential to follow the state and/or local procedures for proper disposal of syringes, needles, and the Redipen. A puncture-resistant container should be used for disposal. Patients should be instructed in how to properly dispose of used syringes, needles, or the Redipen and be cautioned against the reuse of these items. Place in puncture-resistant container, such as a sharps container. Talk to healthcare provider on proper disposal of full container and follow state and local laws. Do not place in household trash or recycle. Do no reuse syringes and keep out of reach of children. Place needle and syringe in biohazard container. Regulations for needle disposal vary. Consult your physician or pharmacist for the regulations in your area. Product does not come with needles. Disposal not addressed. 6

Roferon A (interferon apha 2a) Somavert (pegvisoment) Zorbtive Roche Hep C Hairy cell Leukemia Myelogenous leukemia 3-7 per week (depends on indication) Pfizer acromegally 7 per week (dosed daily) Serno Short bowel syndrome 14 per week (dosed daily; need 2 needles: 1 for reconstitution another for injection) Place entire needle and syringe in punctureresistant container. One can get a sharps container at a local pharmacy or use a coffee can with plastic lid, or a hard plastic container with a screw lid. Check with your healthcare provider for proper disposal of the filled container because there are local and state regulations. Do not throw away in household trash or recycle. Keep out of reach of children. Safely throw away needles and syringes as directed by your health care professional, according to local health regulations. Your health care professional or pharmacist can give you information about the right way to throw away the needles and syringes. Be sure to store and throw away your treatment materials in a way that lowers danger to others. There are special state or local laws for properly disposing used needles and syringes. Your doctor or health care professional will instruct you on how to discard your used syringe and needle and may provide you with a punctureresistant syringe disposal container, called a sharps container. Do not reuse needles; syringes intended for single use only. Always keep your disposal container out of the reach of children. DO NOT throw the needle and syringe in the household trash or recycle. For further information, you may call Serono s Patient Helpline, SeroCareSM, at 1-800-714-2437. Insulin devices Novo Nordisk Diabetes Variable A puncture-resistant container should be recommended to dispose of used needles. 7

Thoroughly instruct and care givers importance of proper disposal of needle. Caution against any reuse of needles should be given. Insulin devices Lilly Diabetes Variable Place the used needle in a puncture-resistant disposable container and properly throw it away as directed by your Health Care Professional. 8