KASPER Quarterly Threshold Analysis Report, Second Quarter 2016

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KASPER Quarterly Threshold Analysis Report, Second Quarter 26 The Kentucky All Schedule Prescription Electronic Reporting System (KASPER) Quarterly Threshold Analysis Report is produced under a Prescription Drug Overdose Prevention for States cooperative agreement between the Kentucky Injury Prevention and Research Center (KIPRC) and the U.S. Centers for Disease Control and Prevention. The report provides information on rates of controlled substance dispensing (number of prescriptions dispensed per, Kentucky residents) by age group and gender based on KASPER controlled substance dispensing data. The analysis includes rates of ) total Schedule II through V controlled substances; 2) alprazolam; 3) buprenorphine/naloxone; 4) hydrocodone; ) methadone; 6) opioids; 7) oxycodone; and 8) total Schedule II stimulants. Additionally, trend graphs for each of the six quarters for which this report has been prepared (First Quarter 2 to Second Quarter 26) are presented for each controlled substance class or specific controlled substance.

Schedule II-V Controlled Substances 2 8 6 4 2 2 8 Rate of Schedule II-V Controlled Substances Prescriptions Dispensed by Age and Gender, 2nd Quarter 26 22 66 8 383 843 92 2 728 92 968-6 7-24 2-34 3-44 4-4 -64 6+ 792 s over the age of 7 were dispensed Schedule II-V Controlled Substance prescriptions at higher rates that males. The highest rate of prescriptions dispensed was for females to 64 years of age with a dispensing rate of prescriptions dispensed per females. Among males, the highest dispensing rate was for males to 64 years of age at the rate of 92 prescriptions per males. Rate of Prescriptions Dispensed per persons 62 6 6 9 8 7 6 4 Rates of Schedule II-V Controlled Substance Prescriptions Dispensed, st Quarter 2 to 2nd Quarter 26 96 69 62 63 Qtr 2 2 Qtr 2 3 Qtr 2 4th Qtr 2 st Qtr 26 2nd Qtr 26 6 93 After a steep increase in the rate of Schedule II-V Controlled Substance prescriptions dispensed between the second quarter and third quarter of 2, the dispensing rate peaked in the fourth quarter of 2. Dispensing declined in the first quarter of 26, and in the second quarter of 26, the rate dipped below the initial rate in the first quarter of 2. 2

Alprazolam Prescriptions dispnesed per persons 2 8 6 4 2 Rate of Alprazolam Prescriptions Dispensed by Age and Gender, 2nd Quarter 26 2 26 2 6 3 89 47 2-6 7-24 2-34 3-44 4-4 -64 6+ 6 62 s over 7 years of age were dispensed alprazolam prescriptions in higher rates than males. The highest rate of alprazolam prescriptions dispensed was for females 6 years of age and older with the rate of 2 prescriptions dispensed per females. 47 46 4 44 43 42 4 4.8 Rates of Alprazolam Prescriptions Dispensed, st Quarter 2 to 2nd Quarter 26 4.79 4.9 4.28 43.68 43.9 st Qtr 2 2nd Qtr 2 3rd Qtr 2 4th Qtr 2 st Qtr 26 2nd Qtr 26 After a peak dispensing rate in the third quarter 2, the dispensing rate for alprazolam prescriptions has steadily declined with the lowest dispensing rate occurring in the second quarter of 26. 3

Buprenorphine-Naloxone Rate of Buprenorphine-Naloxone Prescriptions Dispensed by Age and Gender, 2nd Quarter 26 4 2 8 6 4 2 8 2 99 44 39 6 2 6 2-6 7-24 2-34 3-44 4-4 -64 6+ s 2 to 34 years of age and 3 to 44 years of age have the highest dispensing rates for buprenorphine-naloxone prescriptions at 2 prescriptions per males and 8 prescriptions per males, respectively. s 2 to 34 years of age and 3 to 44 years of age were also dispensed buprenorphine-naloxone prescriptions at higher rates than other females. 4 4 3 3 2 2 Rates of Buprenorphine-Naloxone Prescriptions Dispensed, st Quarter 2 to 2nd Quarter 26 3.83 32.9 3. 36.38 37 38.27 Qtr 2 2 Qtr 2 3 Qtr 2 4th Qtr 2 st Qtr 26 2nd Qtr 26 The trend indicates a steady increase in the dispensing rate for buprenorphine-naloxone prescriptions. The highest dispensing rate is for the second quarter of 26 at the rate of 38.27 prescriptions per persons which is six-quarter increase in dispensing of 24% increase in dispensing. 4

Hydrocodone 3 2 2 Rate of Hydrocodone Prescriptions Dispensed by Age and Gender, 2nd Quarter 26 9 8 4 36 79 73 39 237 26 274 268 29 242-6 7-24 2-34 3-44 4-4 -64 6+ s of all ages were dispensed hydrocodone at higher rates that males. The highest dispensing rates are for females and males to 64 years of age at 274 prescriptions dispensed per females and 268 prescriptions dispensed per males. 4. 2.. 48. 46. 44. 42. 4. 38. 36. Rates of Hydrocodone Prescriptions Dispensed, st Quarter 2 to 2nd Quater 26 48. 49.89 2.7 49.34 43.96 42. st Qtr 2 2st Qtr 2 3rd Qtr 2 4th Qtr 2 st Qtr 26 2nd Qtr 26 The dispensing rates for hydrocodone during the reported quarters continued to decline since the peak rate in the third quarter 2. After the third quarter of 2, the rates declined to the lowest rate occurring in the second quarter of 26 at a rate of 42 prescriptions dispensed per persons.

Methadone Rate of Methadone Prescriptions Dispensed by Age and Gender, 2nd Quarter 26 Prescriptions dipsnesed per persons 9 8 7 6 4 3 2 4-6 7-24 2-34 3-44 4-4 -64 6+ 8 7 3 s were dispensed higher rates of methadone prescriptions than females. The highest rate of dispensing was for males to 64 years of age at the rate of prescriptions per males. 3.6 3. 3.4 3.3 3.2 3. 3 3.42 Rates of Methadone Prescriptions Dispensed, st Quarter 2 to 2nd Quarter 26 3.46 3.6 Qtr 2 2 Qtr 2 3 Qtr 2 4th Qtr 2 st Qtr 26 2nd Qtr 26 3.43 3.26 3.22 The rates for dispensing for methadone prescriptions have remained relatively stable, but show a small decline over the five reported quarters. The highest dispensing rate was for the third quarter of 2 at the rate of 3.6 prescriptions dispensed per persons. The lowest dispensing rate was for the first quarter 26 at the rate of 3.3 prescriptions dispensed per persons. 6

Opioids Prescriptions dispensed per 6 4 3 2 Rate of Opioid Prescriptions Dispensed by Age and Gender, 2nd Quarter 26 2 7 33 249 42 372 489 433 46 36 43-6 7-24 2-34 3-44 4-4 -64 6+ s ages 7 and older were dispensed higher rates of opioid prescriptions than males. The highest rates of hydrocodone prescriptions were dispensed to females and males to 64 years of age at the rates of 46 prescriptions per females and 36 prescriptions per males, respectively. Rates of Opioid Prescriptions Dispensed, st Quarter 2 to 2nd Quarter 26 32 32 3 3 3 3 29 29 28 28 32 37 38 37 3 296 st Qtr 2 2nd Qtr 2 3rd Qtr 2 4th Qtr 2 st Qtr 26 2nd Qtr 26 The rates for the dispensing of opioids during the reported quarters increased from the first quarter of 2 to the third quarter 2, peaking at 32 prescriptions dispensed per persons. After the third quarter of 2, the rates declined to 37 prescriptions dispensed per persons in the second quarter of 26. 7

Oxycodone 4 2 8 6 4 2 Rate of Oxycodone Prescriptions Dispensed by Age and Gender, 2nd Quarter 26 2 2 48 26 7 9 6 99 32 2 87 9-6 7-24 2-34 3-44 4-4 -64 6+ Until age years, females were dispensed higher rates of oxycodone than males. After age years, males were dispensed higher rates than females. The highest dispensing rates were for males and females ages to 64 years at 32 prescriptions dispensed per males and 2 prescriptions dispensed per females. Rate of Oxycodone Prescriptions Dispensed, st Quarter 2 to 2nd Quarter 26 62 6 6 9 8 7 6 4 3 6. 6.49 9.37 9. 8.23 6.7 Qtr 2 2 Qtr 2 3 Qtr 2 4th Qtr 2 st Qtr 26 2nd Qtr 26 The dispensing rate peaked at 6. prescriptions dispensed per persons in the fourth quarter 2 only to decline slightly in the first quarter of 26 and then again in the second quarter of 26. 8

Schedule II Stimulants 2 8 6 4 2 8 6 4 2 Rate of Schedule II Stimulant Prescriptions by Age and Gender, 2nd Quarter 26 8 86 7 6 6 9 49 37 42 2 2 3-6 7-24 2-34 3-44 4-4 -64 6+ 6 Schedule II stimulants include amphetamine (e.g. Adderall) and methylphenidate (e.g. Concerta, Ritalin). The rates for dispensing of Schedule II stimulants are highest for males and females ages to 6 years at 86 prescriptions dispensed per males and 8 prescriptions dispensed per females, respectively. 6. 9. 8. 7. 6.. 4. 3. 2.. 6.7 Rates of Schedule II Stimulants Dispensed, st Quarter 2 to 2nd Quarter 26 4.3 6.4 8.8 9.4 7. st Qtr 2 2nd Qtr 2 3rd Qtr 2 4th Qtr 2 st Qtr 26 2nd Qtr 26 Rates for dispensing of Schedule II stimulants increased over five of the reported quarters with the peak rate of 9.4 prescriptions dispensed per persons in first quarter of 26. The dispensing rate declined in the second quarter of 26 to 7. prescriptions dispensed per persons. 9

Your feedback is important to us. Please take a few minutes to evaluate this report. Please click on this link to take you directly to the evaluation survey: https://www.surveymonkey.com/r/2qtr26kasperthresholdreportfeedback. This project report is a collaboration between the Kentucky Injury Prevention and Research Center (KIPRC) and the Kentucky Cabinet for Health and Family Services. This report, and prior reports, are available on the KASPER website at http://www.chfs.ky.gov/os/oig/kaspertrendreports and on KIPRC s website at http://www.mc.uky.edu/kiprc/.