Division of Nuclear Medicine Procedure / Protocol

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Division of Nuclear Medicine Procedure / Protocol MYOCARDIAL SPECT PERFUSION REST and REDISTRIBUTION CPT CODE: 78460, 78464 FOR USE WITH THALLIUM 201 ONLY UPDATED: MARCH 2012 Indications: Patient Prep: Scheduling: Resting thallium is used in the determination of myocardial viability (the syndrome of dysfunctional hypoperfused myocardium which improves in function after revascularization). See the Myocardial Stress Test Prep Protocol. The test will consist of 2-3 appointments. First appointment (rest only) will be for 60 minutes. Second appointment (4-6 hrs later) will be for 60 minutes. Third appointment (24 hrs after first appointment) will be for 60 minutes. Radiopharmaceutical & Dose: The rest dose is 3mCi Thallium adjusted per the current age & weight nomogram. There is no injection the 2 nd set of images. If the 3 rd set of images is required a 1mCi redistribution dose will be needed. Imaging Device: Data Acquisition: GE Millennium VG or GE Infinia Hawkeye with LEHR collimators. Please note, that at this time Hawkeye is not For the Millennium VG, select the following from the Myocardial Folder: Select Rest TL201 ECT for the rest images Select Rest Redistribution for the 2 nd image. Select Rest TL201 ECT for the 3 rd set of images. These images are not gated. For the Infinia Hawkeye, select USER, then select the following from the UW CARDIAC FOLDER: Select One Day TL for all images. Use Rest for the 1 st images. Use Redistribution for the 2 nd images. Use Rest for the 3 rd set of images. Delete the other image (gated) sets; they are not used for this study. These images are not gated.

Acquisition Parameters: The Infinia Hawkeye cameras must be in the L Mode configuration. Infinia Hawkeye Rest Stress Redistribution Tomo Key Parameters Mode L L L Start Angle 270 270 90 Patient Location Feet First Supine Feet First Supine Feet First Supine Acquire CT/AC No No No Image Settings Zoom 1.3 1.3 1.3 Matrix 64 x 64 64 x 64 64 x 64 Pan Y 0 0 0 Scan Mode Step & Shoot Check Check Check Seconds 45 35 45 Tomo Corrections Energy session TL201 (70 & 167) TL201 (70 & 167) TL201 (70 & 167) Collimator LEHR LEHR LEHR COR Correction Check Check Check Tomo CT/AC Parameters Nothing Nothing Nothing Tomo Location Parameters Mode L L L Start Angle 270 270 270 Patient Location Feet First Supine Feet First Supine Feet First Supine Detector Settings Detectors 1 and 2 Check Check Check Rotation Total Angular Range 180 180 180 View Angle 3 3 3 Direction CCW CCW CW Workflow Release at end of scan Check Check Check FOV Settings Number of FOVs 1 1 1 FOV time multiplier 1.0 1.0 1.0 Rough Overlap 4 4 4 Direction Table In Table In Table In Table Height Select Default Default Default Tomo Admin Parameters Body Part Chest Chest Chest

Millennium VG REST TL201 ECT STRESS TL201 ECT ECT Tab Label TL201 Spect TL201 Spect Pharmaceutical TL201 TL201 Dose 3.0 3.0 Isotope: Select TL201 TL201 Heads: Head 1 and Head 2 Check Check Head 1 Collimator VP45 VP45 View RST_ECT RST_ECT Head 2 Collimator: VP45 VP45 View Gspect Parameters Frames/Cycle: Acquisition Mode: Select ECT Parameters Angular Range 90.0 90.0 Angular Step 3.0 3.0 Frame Time 45 35 Velocity 2.0 2.0 Direction: CCW Check Check ECT Type: Step & Shoot Check Check Stop Conditions Select Gantry Position 0.0 0.0 PVC Thresholds High%: Low%: Extended Tab Energy Window Center 70.0 167.0 70.0 167.0 Low 15 10 15 10 High % 15 10 15 10 Corrections Energy Check Check Linearity Check Check Sensitivity Check Check COR Check Check Home Position Factory Check Check Select Thallium Thallium Rate: Normal Check Check Frame Size: Select 64 64 Mirror: Select NO NO Transform Center X 0.0 0.0 Center Y 0.0 0.0 Zoom 1.28 1.28 Rotation 0.0 0.0 Patient Position: Select Supine Supine Patient Orientation: Select Legs In Legs In

Procedure: 1. For outpatients upon arrival to the nuclear medicine department, females will be asked to change from the waist up into 2 hospital gowns (alternating front and back openings); the brassiere needs to be removed for imaging. This is per the physicians. Male patients have no immediate prep. 2. A nuclear medicine technologist will interview the patient, verifying the patient with 2 forms of identification (i.e. DOB, spelling the name, MR #). A brief description of the test will be given and the patient allowed to ask any questions. 3. The radiopharmaceutical can be directly injected into a vein, making sure to flush the syringe with blood at least once. For inpatients or outpatients with a working IV in place, the radiopharmaceutical shall be injected and flushed with a 0.9% Sodium Chloride 10cc syringe. 4. The patient will be asked to wait in the cardiac waiting room for 15 minutes. 5. The appropriate protocol is selected (see the Data Acquisition section) depending on the camera 6. Patients are asked to remove any metal objects from the chest/torso areas as to not interfere with 7. The patient is asked to lie supine on the imaging table with their arms above their head. The camera faces do not touch the patient. The patient is instructed to lay still and breathe normally 8. Upon completion of the images, the patient is assisted up from the table and asked to wait in the cardiac waiting room until the images are reviewed. This is to verify there is no technical data missing and there is no excessive patient movement during the images requiring the pictures to be taken again. 9. The images are then processed per the Myocardial Processing Protocol. It may be necessary to have the reading physician of the day review the images before the patient is released to leave. 10. Once it is determined that the patient may leave, in-patients may be sent back to the floor and out-patients may re-dress. A copy of the Myocardial Dietary Restrictions for Thallium Cardiac Stress Test is explained and sent with the patient. 11. At the time of the second appointment (resting part of the study), the nuclear medicine technologist will interview the patient, verifying the patient with 2 forms of identification (i.e. DOB, spelling the name, MR #). Female patients will be asked to change from the waist up into 2 hospital gowns (alternating front and back openings); the brassiere needs to be removed for imaging. 12. The appropriate protocol is selected (see the Data Acquisition section) depending on the camera 13. Patients are asked to remove any metal objects from the chest/torso areas as to not interfere with 14. The patient is asked to lie supine on the imaging table with their arms above their head. The camera faces do not touch the patient. The patient is instructed to lay still, breath normally 15. Upon completion of the images, the patient is removed from the imaging table and asked to wait in the cardiac waiting room while the images are reviewed. At this time, the images need to be reviewed by the reading physician of the day to determine if the 3 rd set of images (24hr images) are needed. If so, proceed to the next step. If the 3 rd set of images are not needed, the procedure is not complete. 16. The patient is asked to return at the designated time the following day for the 3 rd set of images. There are no food or beverage restrictions for the last set of images. 17. At the time of the third appointment, the nuclear medicine technologist will interview the patient, verifying the patient with 2 forms of identification (i.e. DOB, spelling the name, MR #). Female patients will be asked to change from the waist up into 2 hospital gowns (alternating front and back openings); the brassiere needs to be removed for imaging.

18. If the 24hr images are needed a 1mCi dose of Thallium can be directly injected into a vein, making sure to flush the syringe with blood at least once. For inpatients or outpatients with a working IV in place, the radiopharmaceutical shall be injected and flushed with a 0.9% Sodium Chloride 10cc syringe. Out-patients with peripheral IV s should have the IV discontinued at this time. 19. The appropriate protocol is selected (see the Data Acquisition section) depending on the camera 20. Patients are asked to remove any metal objects from the chest/torso areas as to not interfere with 21. The patient is asked to lie supine on the imaging table with their arms above their head. The camera faces do not touch the patient. The patient is instructed to lay still, breath normally 22. Upon completion of the images, the patient is removed from the imaging table and asked to wait in the cardiac waiting room while the images are reviewed. 23. The images are processed per Myocardial Processing Protocol. The necessary screen captures are sent to PACS. It may be necessary to have the reading physician of the day review the images before the patient is released to leave. 24. Once it is determined that the patient may leave, in-patients may be sent back to the floor and out-patients may re-dress. A handout with the food and beverage guidelines will be sent with all patients. Image Processing & PACS: Display the 4hr and initial images using the Myocardial Spect Processing Protocol. Display the 24hr and initial images again using the Myocardial Spect Processing Protocol. Interpretation: A single resting study may define myocardial viability. Follow-up 4-6 hour or 24-hour imaging improves the sensitivity of detecting viable myocardium in initial defects. Reviewed By: S. Perlman, D. Fuerbringer, S. Knishka, M. Zasadil Scott B. Perlman, MD, MS Chief, Nuclear Medicine Derek Fuerbringer, CNMT Manager, Nuclear Medicine Scott Knishka, RPh, BCNP Radiopharmacist Mary L. Zasadil, MD Director, Nuclear Cardiology