PRESEPTAL AND ORBITAL CELLULITIS IN CHILDREN- CLINICAL GUIDELINE V3.0

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PRESEPTAL AND ORBITAL CELLULITIS IN CHILDREN- CLINICAL GUIDELINE V3.0 Page 1 of 8

1. Aim/Purpose of this Guideline 1.1. This guideline applies to medical and nursing staff caring for a child with Preseptal and Orbital Cellulitis. 2. The Guidance 2.1. Preorbital and orbital cellulitis are both infections that may present with swelling and erythema of the eyelid and periorbital tissues. The terms preseptal and septal may be used instead of periorbital and orbital respectively The key differential to these infections is whether there is infection posterior to the orbital septum, as this has serious consequences in terms of vision, serious CNS infection or cavernous sinus thrombosis. 2.2. Preseptal cellulitis is most common in the under 5year age group. There is often a site of initial infection such as a minor injury to the skin or insect bite to the periorbital tissues. Infection can sometimes arise secondary to an URTI. There is tenderness, swelling, warmth and redness of tissues. Fever may be present. Swelling may be sufficient to obscure the eye, in such cases an ophthalmological examination is essential to exclude orbital cellulitis. The most common organisms are Strep pyogenes, Strep pneumoniae and Staph aureus. Haemophilus influenza may be a cause in unimmunised children and may be associated with concurrent meningitis. Atypical organisms including fungi may be responsible in immunocompromised and diabetics. Mixed aerobes and anaerobes are more common in the over 15 years. 2.3. Orbital cellulitis usually arises secondary to spread from the ethmoid sinus and bone, which progresses to subperiosteal abscess then orbital abscess or cellulitis.it can then extend more posteriorly to cause cavernous sinus thrombosis and meningitis. There may be a co existent URTI or history of recent infection. Risk factors for intracranial infection include those > 7years; subperiosteal abscess; headache and fever persisting despite IV antibiotics; immunocompromised and diabetics. Bilateral periorbital oedema may indicate cavernous sinus thrombosis. In cases where meningitis is suspected LP may be required but should only be undertaken after imaging as intracranial extension may be silent. Page 2 of 8

3. Monitoring compliance and effectiveness Element to be monitored Lead Tool Frequency Reporting arrangements Acting on recommendations and Lead(s) Compliance with guideline and flow chart process outlined in appendix 3 Paediatric Consultant Audit Lead Individual case by case review of medical notes or specific audit tool As required or indicated Paediatric consultant Directorate audit and guidelines meeting Paediatric consultant Directorate audit and guidelines meeting Required actions will be identified and completed in3-6 months Change in practice and lessons to be shared Possible wording to use for this column. Required changes to practice will be identified and actioned within 3-6 months. A lead member of the team will be identified to take each change forward where appropriate. Lessons will be shared with all the relevant stakeholders 4. Equality and Diversity 4.1. This document complies with the Royal Cornwall Hospitals NHS Trust service Equality and Diversity statement which can be found in the 'Equality, Diversity & Human Rights Policy' or the Equality and Diversity website. 4.2. Equality Impact Assessment The Initial Equality Impact Assessment Screening Form is at Appendix 2. Page 3 of 8

Appendix 1. Governance Information Document Title PRESEPTAL AND ORBITAL CELLULITIS IN CHILDREN- CLINICAL GUIDELINE V3.0 Date Issued/Approved: 10 th Nov 2017 Date Valid From: 10 th Nov 2017 Date Valid To: 10 th Nov 2020 Directorate / Department responsible (author/owner): Dr.Sian Harris- Paediatric Consultant Contact details: 01872 253041 Brief summary of contents Clear guidance on management of preseptal and orbital cellulitis in children. Suggested Keywords: Target Audience Executive Director responsible for Policy: Cellulitis Preseptal Orbital children RCHT PCH CFT KCCG Medical Director Date revised: 10 th Nov 2017 This document replaces (exact title of previous version): Approval route (names of committees)/consultation: Divisional Manager confirming approval processes Name and Post Title of additional signatories Name and Signature of Divisional/Directorate Governance Lead confirming approval by specialty and divisional management meetings PRESEPTAL AND ORBITAL CELLULITIS IN CHILDREN- CLINICAL GUIDELINE V2.0 Paediatric consultants Directorate audit and guidelines meeting ENT consultant Microbiology consultant David Smith Not Required {Original Copy Signed} Name: Caroline Amukusana Signature of Executive Director giving {Original Copy Signed} approval Page 5 of 8

Publication Location (refer to Policy on Policies Approvals and Ratification): Document Library Folder/Sub Folder Links to key external standards Related Documents: Training Need Identified? Internet & Intranet Intranet Only Clinical / Paediatrics none none no Version Control Table Date Version No Summary of Changes Changes Made by (Name and Job Title) July 13 V1.0 Initial Issue Dr.S.Harris paediatric consultant January 15 V2.0 Review of content. Reformat into template for documents library. Dr.S.Harris paediatric consultant Nov 2017 V3.0 No changes Sian Harris, Paediatric Consultant All or part of this document can be released under the Freedom of Information Act 2000 This document is to be retained for 10 years from the date of expiry. This document is only valid on the day of printing Controlled Document This document has been created following the Royal Cornwall Hospitals NHS Trust Policy on Document Production. It should not be altered in any way without the express permission of the author or their Line Manager. Page 6 of 8

Appendix 2. Initial Equality Impact Assessment Form This assessment will need to be completed in stages to allow for adequate consultation with the relevant groups. Name of Name of the strategy / policy /proposal / service function to be assessed PRESEPTAL AND ORBITAL CELLULITIS IN CHILDREN- CLINICAL GUIDELINE V3.0 Directorate and service area: Child Health Name of individual completing assessment: Dr Sian Harris Is this a new or existing Policy? Existing Telephone: 01872252800 1. Policy Aim* Clear guidance on the management of preseptal and orbital cellulitis Who is the strategy / policy / proposal / service function aimed at? 2. Policy Objectives* Clear guidance on the management of preseptal and orbital cellulitis 3. Policy intended Outcomes* Evidenced based and standardised practice 4. *How will you measure the outcome? Audit and review 5. Who is intended to benefit from the policy? Children and families 6a Who did you consult with Workforce Patients Local groups x External organisations Other b). Please identify the groups who have been consulted about this procedure. Please record specific names of groups Clinical Guideline Group Child Health Directorate Page 7 of 8

What was the outcome of the consultation? Guideline agreed 7. The Impact Please complete the following table. If you are unsure/don t know if there is a negative impact you need to repeat the consultation step. Are there concerns that the policy could have differential impact on: Equality Strands: Yes No Unsure Rationale for Assessment / Existing Evidence Age Sex (male, female, trans-gender / gender reassignment) Race / Ethnic communities /groups Disability - Learning disability, physical impairment, sensory impairment, mental health conditions and some long term health conditions. Religion / other beliefs Marriage and Civil partnership Pregnancy and maternity Sexual Orientation, Bisexual, Gay, heterosexual, Lesbian You will need to continue to a full Equality Impact Assessment if the following have been highlighted: You have ticked Yes in any column above and No consultation or evidence of there being consultation- this excludes any policies which have been identified as not requiring consultation. or Major this relates to service redesign or development Page 8 of 8

8. Please indicate if a full equality analysis is recommended. Yes No 9. If you are not recommending a Full Impact assessment please explain why. No areas indicated Signature of policy developer / lead manager / director Chris Warren Date of completion and submission 10 Nov 17 Names and signatures of members carrying out the Screening Assessment 1. Sian Harris 2. Human Rights, Equality & Inclusion Lead Keep one copy and send a copy to the Human Rights, Equality and Inclusion Lead c/o Royal Cornwall Hospitals NHS Trust, Human Resources Department, Knowledge Spa, Truro, Cornwall, TR1 3HD This EIA will not be uploaded to the Trust website without the signature of the Human Rights, Equality & Inclusion Lead. A summary of the results will be published on the Trust s web site. Signed Chris Warren Date 10/11/17 Page 9 of 8

Appendix 3: Flow Chart Child presenting with swelling of eyelid and/or periorbital Mild swelling NO concerning features on examination no Proptosis no ophthalmoplegia or pain on eye movements no chemosis no headache normal visual acuity normal light reflexes systemically well no CNS signs or symptoms treat with oral antibiotics Augmentin (if no fever consider allergic reaction or nephrotic syndrome) Discharge home with advice to return if worsening or any concerning features. Clinical Guideline for the management of Preseptal and Orbital Celluli ti s in Children. More marked swelling or unwell, Swelling of eyelid and periorbital tissues but eye visible and no concerning features no Proptosis no ophthalmoplegia or pain on eye movements no chemosis no headache normal visual acuity normal light reflexes no CNS signs or symptoms ADMIT Take bloods including FBC and blood cultures Start IV antibiotics Metronidazole and Ceftriaxone (if<4 weeks Cefotaxime) Clindamycin if penicillin allergic If symptoms progress seek ophthalmological and ENT review. Consider CT imaging Page 3 of 8 Swelling such that unable to examine eye properly or features suggest Orbital cellulitis or infection posterior to orbital septum Proptosis Ophthalmoplegia or pain with eye movements diplopia Reduced visual acuity Abnormal light reflexes Conjunctival hyperaemia or Chemosis of globe Severe or persistent headache Toxic or systemically unwell CNS signs or symptoms ADMIT Proceed to Orbital Cellulitis Table

ORBITAL CELLULITIS ADMIT ALL ENT/ OPHTHALMOLOGY ASSESSMENT WITHIN 6 HOURS OF ADMISSION SENIOR ENT OPINION TO PLAN MANAGEMENT IV ANTIBIOTICS Vancomycin + Ceftriaxone ( <4weeks age use Cefotaxime)+ Metronidazole (if penicillin allergic Vancomycin+ ciprofloxacin +Metronidazole) DECONGESTANT NOSE DROPS, ANALGESICS If patient is MRSA carrier then discuss with Microbiology BILAT. VISUAL AND REL. AFF. PUPIL DEFECT VISUAL ACUITY & NO VISUAL LOSS NEUROLOGICAL SYMPTOMS OR VISUAL ACUITY COLOUR VISION NO SIGNIFICANT &SIGNS FAILING OR GONE SATISFACTORY BUT PROPTOSIS/GLOBE AND/OR FIED GLOBE SIGNIFICANT PROPTOSIS DISPLACEMENT? CAVERNOUS SINUS & CHEMOSIS THROMBOSIS OR OPHTHALMOPLEGIA EMERGENCY CT +/- MRI EMERGENCY CT SINUSES (A & COR) CONSIDER CT Consider if on best antibiotic cover 100 MINS IF POSSIBLE WITHIN 24 HOURS LIAISE WITH TERTIARY TO SAVE EYE WITHIN 1-2 HOURS NEUROLOGY/NEUROSURGERY SURGICAL DRAINAGE DOESN T IMPROVE IMPROVES (ETERNAL SINUS OR LOCALISED APPROACH) ABSCESS Switch to ORAL ABS once sustained improvement