Liver cancer and normal cell lines

The Essentials of Life Science Research Globally Deed Liver cancer and normal cell lines ATCC No. Name Tissue Cell Type Disease Oganism Age Ethnicity Genes Expressed HTB-79 Capan-1 pancreas: adenocarcinoma Homo sapiens 40 years Caucasian mucin, Blood Type A; Rh+; HLA A2, A9, B13, B17 HTB-52 SK-HEP-1 /ascites Endothelial adenocarcinoma Homo sapiens 52 years Caucasian 8306 MC/9 mast cell Allergen 13 days histamine; leukotrienes 1439 clone 9 Epithelial carcinogenesis HB-8108 B72.3 HB-8107 B25.2 HB-8106 B6.2 HB-8110 B38.1, spleen,, spleen,, spleen,, spleen, Carcinoma Carcinoma Carcinoma, sarcoma Carcinoma, sarcoma 4 weeks 2064 DMS 153 lung: carcinoma; small cell lung cancer Homo sapiens 44 years Caucasian adrenocorticotropin (adrenocorticotropic hormone, ACTH); bombesin; calcitonin; calcitonin gene related peptide (CGRP); oxytocin - neurophysin (OT-NP); 17 beta estradiol, Leu 7 +; My23 +; CD11b + 1837 SU.86.86 pancreas: ductal carcinoma Homo sapiens 57 years Caucasian carcinoembryonic antigen (CEA) 5822 NCI-N87 [N87] stomach: gastric carcinoma Homo sapiens myc +; erb B2 + 2235 SNU-182 grade III/IV, hepatocellular carcinoma Homo sapiens 2238 SNU-423 grade III/IV, pleomorphic hepatocellular carcinoma 24 years Asian Blood Type O; Rh + Homo sapiens 40 years Asian Blood Type B; Rh + 2234 SNU-449 grade II-III/IV, hepatocellular carcinoma Homo sapiens 52 years Asian 2236 SNU-475 grade II-IV/V, hepatocellular carcinoma Homo sapiens 43 years Asian Blood Type AB; Rh +

2237 SNU-387 grade IV/V, pleomorphic hepatocellular carcinoma 7549 Hs 817.T hepatic ductal carcinoma Homo sapiens 41 years Asian Blood Type O; Rh + unknown, either human or mouse 2117 LMH hepatocellular carcinoma Gallus gallus 2118 LMH/2A hepatocellular carcinoma Gallus gallus 10741 10742 11997 C3A [HepG2/ C3A, derivative of Hep G2 (ATCC HB- 8065)] C3A [HepG2/ C3A, derivative of Hep G2 (ATCC HB- 8065)] hepatocellular carcinoma Homo sapiens hepatocellular carcinoma Homo sapiens 15 years adolescent 16 years adolescent Caucasian Caucasian HEP G2/2.2.1 hepatocellular carcinoma Homo sapiens 15 years Caucasian 2233 SNU-398 hepatocellular carcinoma Homo sapiens 42 years Asian Blood Type O; Rh + HB-8064 HB-8065 Hep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B] Hep G2 [HEPG2] hepatocellular carcinoma Homo sapiens hepatocellular carcinoma Homo sapiens 2406 PLHC-1 hepatocyte hepatocellular carcinoma Pan troglodytes HB-8065.1 Hep G2/SF hepatocellular carcinoma Homo sapiens 8 years juvenile 9 years juvenile Black Black alpha-fetoprotein (alpha fetoprotein); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1-antitrypsin); transferrin; alpha1 antichymotrypsin; (alpha-1-antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen;, complement (C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein); alpha2 HS glycoprotein (alpha-2-hs-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol-binding protein) alpha-fetoprotein (alpha fetoprotein); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1-antitrypsin); transferrin; alpha1 antichymotrypsin; (alpha-1-antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen;, complement (C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein); alpha2 HS glycoprotein (alpha-2-hs-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol-binding protein) alpha fetoprotein (alpha-fetoprotein); hepatitis B surface antigen (HBsAg); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1- antitrypsin); transferrin;, alpha1 antichymotrypsin (alpha-1- antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen; complement (C3, C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein);, alpha2 HS glycoprotein (alpha-2-hs-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol- alpha fetoprotein (alpha-fetoprotein); hepatitis B surface antigen (HBsAg); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1- antitrypsin); transferrin;, alpha1 antichymotrypsin (alpha-1- antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen; complement (C3, C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein);, alpha2 HS glycoprotein (alpha-2-hs-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol- cytochrome P450 (CYP) 2 Order online at www.atcc.org, call 800.638.6597, 703.365.2700, or contact your local distributor.

8024 PLC/PRF/5 Alexander cells hepatoma Homo sapiens hepatitis virus B surface antigen (HBsAg) 2082 WCH-17 hepatoma Marmota monax 1830 Hepa 1-6 hepatoma 2026 Hepa-1c1c7 hepatoma cytochrome P450IA1 2217 BpRc1 hepatoma cytochrome P450IA1 2218 tao BpRc1 hepatoma cytochrome P450IA1 2710 c12 (B15ECiii2) epithelial hepatoma 2711 c37 (B7IFi1) epithelial hepatoma 2712 vt{2} epithelial hepatoma 2716 2717 c1 (B6NLxv1c2) c4 (B13NBii1) hepatoma epithelial hepatoma CCL-144 MH1C1 hepatoma 1548 H-4-II-E hepatoma 1578 H4TG hepatoma 1600 H4-II-E-C3 hepatoma 1710 RTH-149 hepatoma 1601 McA-RH7777 hepatoma; Morris hepatoma 7777 1602 McA-RH8994 hepatoma; Morris hepatoma 8994 1603 N1-S1 Fudr hepatoma; Novikoff hepatoma TIB-164 14.8 spleen, B Lymphoma 2254 AML12 hepatocyte normal 3 months 5892 NCI-H1755 [H1755] lung: stage 4, adenocarcinoma; non-small cell lung cancer Homo sapiens 65 years Caucasian albumin, alpha fetoprotein (AFP, alpha-fetoprotein); albumin; alpha 1 antitrypsin (alpha-1-antitrypsin); amylase rat serum albumin; complement components (especially C9) tyrosine aminotransferase; albumin; transferrin; prothrombin alpha-fetoprotein (AFP, alpha fetoprotein) alpha-fetoprotein (AFP); alpha fetoprotein immunoglobulin; monoclonal antibody; against mouse B cell () precursors (CD45RA), The epitope recognized requires expression of exon A. albumin; human transforming growth factor alpha (TGF alpha); mouse TGF alpha. Expression of specific proteins decreases with time in culture, but is reactivated by growing the cells in serum free medium. Order online at www.atcc.org, call 800.638.6597, 703.365.2700, or contact your local distributor. 3

5978 NCI-H735 [H735] lung: 2706 THLE-2 /left lobe stage E, carcinoma; small cell lung cancer These immortalized human cells constitute an in vitro model for pharmacotoxicological studies and for the investigation of etiology and pathogenesis of human hepatocellular carcinoma. Homo sapiens 58 years Caucasian Homo sapiens 2643 ZFL [ZF-L] Danio rerio HB-12346 11233 CCL-9.1 AC133.1 Lymph node,, bone, Peripheral blood, Blood, Bone marrow lymphoblast B THLE-3 /left lobe Homo sapiens NCTC clone 1469 [derivative of NCTC 721] newborn H-2k 1638 NMuLi weanling 1995 H2.35 hepatocyte 6 weeks 2390 FL83B hepatocyte 6447 NMu3Li 15 to 17 days gestation TIB-73 BNL CL.2 embryo TIB-74 BNL SV A.8 embryo TIB-75 BNL 1ME A.7R.1 embryo TIB-76 BNL 1NG A.2 embryo 6194 OHH1.Li 2301 SOB-15 epithelial 1442 BRL 3A fibroblast 2452 Sl/Sl4 /stroma Mast Cell embryo 2453 2454 Sl/Sl4 hscf220 Sl/Sl4 hscf248 /stroma Mast Cell embryo fawn immunoglobulin; monoclonal antibody; against a subset of human CD34 antigens The cells express cytokeratin 18 and albumin in early passage, whereas higher-passage cells in logarithmic-phase growth also express cytokeratin 19. cholesterol; glycogen /stroma Mast Cell embryo stem cell factor (SCF) somatomedin like multiplication stimulating activity (MSA) 4 Order online at www.atcc.org, call 800.638.6597, 703.365.2700, or contact your local distributor.

10998 L.N. 4159 temperature sensitive T antigen HB-34 15-79-2 HB-8770 FHCR-1-2075/FH5 [FH5] 6530 22F.Li, spleen pre-b lymphoblast B fetus immunoglobulin; mu heavy chain (not secreted) Zalophus californianus immunoglobulin; monoclonal antibody; against trifucosylated type 2 chain glycolipids PHONE 800.638.6597 703.365.2700 EMAIL tech@atcc.org WEB www.atcc.org CB-0513-01 2013 American Type Culture Collection. The ATCC trademark and trade name, any and all ATCC catalog numbers and any other trademarks listed in this publication are trademarks of the American Type Culture Collection unless indicated otherwise. These products are for laboratory use only. Not for human or diagnostic use. ATCC products may not be resold, modified for resale, used to provide commercial services or to manufacture commercial products without prior ATCC written approval.