Innovation and quality in managing cardiovascular patients: Role of the BPC in Brazil. Fábio P. Taniguchi, MD, MBA, PhD Principal Investigador

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Innovation and quality in managing cardiovascular patients: Role of the BPC in Brazil Fábio P. Taniguchi, MD, MBA, PhD Principal Investigador

BPC - Brazil Heart Failure Coronary Artery Disease Atrial fibrilattion Inpatients Atrial fibrilattion Outpatients

Clio Main Objective Evaluate the guidelines adhesion rates of SUS hospitals in Heart Failure, Acute Coronay Syndrome and Atrial fibrilattion before and after the implementation of a good practice program.

Secondary objectives evaluate the hospital readmission and death rates at 30 days and at 6 months following the inclusion in the study evaluate average length of stay assess patients adherence rates to medical treatment prescribed at discharge, 30 days and 6 months after hospital admission evaluate health professional adherence 5

Secondary objectives evaluate patients quality of life and health perception at discharge and at 6 months following hospital admission evaluate the occurrence of in-hospital clinical outcomes evaluate the occurrence of clinical outcomes related to the index hospitalization at 30 days and at 6 month follow up. estimate direct costs related to the disease in each of the three arms of the project

Possibilities Generate new knowledge Identify areas for future quality improvements efforts and measures Drive measure improvement and construct Improve the development of measures, guidelines and implementation strategies Determine the safety and effectiveness of therapies applied in clinical practice

BPC - Brazil

Timeline Local Ethics Committee Baseline analysis Interventions Publications Patient inclusion Program Implementation Results

Study Design

Elegibility Criteria Atrial fibrilattion * Older than 18 years old.. * Primary diagnoses of AF * consent to participate. * history of isolated atrial fibrilattion and sinus rhytm at the time of consultation. 11

Elegibility Criteria Acute Coronary Syndrome * Older than 18 years old. * Primary diagnoses of ACS * consent to participate * comorbidities with life expectancy of less than 1 year. * after a surgical or percutaneous myocardial revascularization or major surgical procedures over the same hospitalization.

Elegibility Criteria Heart Failure * Older than 18 years old * Primary diagnosis(acute, new or decompesated HF). * consent to participate Dyspnea for other causes; Presence of acute coronary syndrome or ongoing ischemia; Suspicious of pulmonary embolism; Advanced renal disease under dialysis; Planned transfer to another facility or with planed in-hospital length of stay of less than 24 hours; Have other clinical morbidities with life expectation of less then 1 year. Have BNP less than or equal to 100, or NT-proBNP less than or equal to 400 (if available).

The hospital and the team Heart Failure Atrial fibrilattion l Acute Coronary Syndrome

Data Collect 15

ecrf bpc.hcor.novatela.com.br

ecrf

Quality Indicators Acute Coronary Syndrome Early Aspirine Aspirine at discharge Beta-Blockers at discharge ACE/ARB at discharge when left vetricule systolic dysfunction Statins at dischrage High blood pressure control Smoking cessation Door - Needle time 30 minutes Door-balloon time 90 minutes

Quality Indicators Heart Failure ACE/ARB at discharge Beta-Blockers at discharge Left ventricule measure Outpatient return visit after discharge Aldosterone antagonist at discharge

Quality Indicators Atrial fibrilattion ACE/ARB at discharge with left vetricule systolic dysfunction Thromboembolic risk stratification Beta-blocker therapy for patients with CAD or systolic dysfunction that require control of the heart rate Anticoagulant therapy INR outpatient visit program Bleeding risk evaluation Statins in patients with AF and CAD, stroke or PVD 21

Achievement Criteria Adherence in the guidelines indicators in 85% or greater composite score

Patient Material

Hospital Material

BPC Sites Currently: seven hospitals -Universidade Federal do Rio Grande do Sul Dr. Luis Eduardo Paim Rohde Universidade Federal de São Paulo Dr. Angelo Amato Vicenzo de Paola -Hospital Universitário Pedro Ernesto (UERJ) Dr. Denilson Campos de Albuquerque -Hospital Das Clinicas/ Universidade Federal de Minas Gerais Dr. Antonio Pinho Riberio -Hospital Procape Universidade Federal de Pernambuco Dr. Sergio Montenegro -Hospital de Messejana Dr. Joao David de Souza Neto -Instituto Nacional de Cardiologia Dra. Ana Patricia de Oliveira 26

Site Visit

BPC - Brazil October 2015 I BPC Meeting May 2016 Patient inclusion July 2016 II BPC Meeting Today - 09/24/2016 737 patients included New centers AF 264 Webinars programation Protocols dissemination ACS 227 Full online reports HF 246 Colaborattive team 200 210 220 230 240 250 260 270

New Centers - Universidade Federal Paraíba Dr. Marco Antonio Vivo Barros - Universidade Federal de Goias Dr. Weimar Sebba Barroso -Universidade Federal de Alagoas Dra. Maria Alayde Mendonça da Silva -Universidade Federal de Mato Grosso Dr. Luiz Cesar Nazario Scala - Universidade Federal de Uberlândia Dr. Elmiro Santos Resende - Hospital Geral de Palmas Dr. Wallace André Silva -Universidade Federal da Bahia Dr. Roque Aras Jr.

Program in Brazil

Program in Brazil

Thank you! ftaniguchi@hcor.com.br