June 4 th - 6 th 2014 Milazzo, Italy. 3 rd Workshop on Synaptic Plasticity: from bench to bedside

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June 4 th - 6 th 2014 Milazzo, Italy 3 rd Workshop on Synaptic Plasticity: from bench to bedside

WELCOME Dear Colleagues and Friends, We welcome you to the 3rd Workshop on Synaptic Plasticity: from bench to bedside. The success of the first and second editions held in Taormina in 2010 and 2012 and the numerous unresolved issues in our complex field were strong arguments in favor of organizing a third edition of the Conference. This third edition will focus on rehabilitation in movement disorders and on maladaptive plasticity in Parkinson s disease dealing with dyskinesia and impulse control disorders. In addition there will be a symposium dedicated to the role of cerebellum in basal ganglia disorders. An entire symposium will be dedicated to diffusion tensor imaging as a tool to monitor longitudinally structural plasticity in neurological diseases. Finally the last symposium will focus on the importance of cortical re-organizations in brain tumors and how information can be used by neurosurgeons to plan and perform tumor excision. The Congress Chairpersons Angelo Quartarone and Paolo Girlanda

Congress Chairpersons Angelo Quartarone (Messina, Italy) Paolo Girlanda (Messina, Italy) International Scientific Committee Mark Hallett (Bethesda, USA) John Rothwell (London, UK) Paolo Calabresi (Perugia, Italy) Maria Felicia Ghilardi (New York, USA) Faculty Yaniv Assaf (Tel-Aviv, Israel) Giovanni Abbruzzese (Genoa, Italy) Alberto Bizzi (Rozzano, Italy) Angela Cenci (Lund, Sweden) Chiara Cirelli (Madison, Wisconsin, USA) Christiaan I. De Zeeuw (Amsterdam, Netherlands) Hugues Duffau (Montpellier, France) Giuseppe Frazzitta (Gravedona, Italy) Jean Antoine Girault (Paris, France) Lice Ghilardi (New York, USA) Ann Graybiel (Cambridge, Massachusetts, USA) Mark Hallett (Bethesda, USA) Matilde Inglese (New York, USA) H.A. Jinnah (Atlanta, USA) Asha Kishore (Trivandrum, India ) Giacomo Kock (Rome, Italy) Melissa Nirenberg (New York, USA) Randolph J. Nudo (Kansas City, USA) Giselle Petzinger (Los Angele, USA) Pietro Pietrini (Pisa, Italy) Vincenzo Rizzo (Messina, Italy) Paolo Maria Rossini (Rome, Italy) Daniele Volpe (Verona, Italy)

Wednesday - June 4 th, 2014 14.30-15.00 Introduction, Welcome and overview Paolo Girlanda, Angelo Quartarone Session 1 Plasticity, movement disorders and rehabilitation Chairs: 15.00-16.00 Main Lecture Plasticity and learning in Parkinson s disease Maria Felicia Ghilardi 16.00-16.30 Basic mechanism of exercise in animal models of PD Giselle Petzinger 16.30-17.00 Does rehabilitation improve plasticity in Parkinson s disease? Giuseppe Frazzitta 17.00-17.30 Coffee Break 17.30-18.00 Plasticity in dystonia: implication for rehabilitation? Giovanni Abbruzzese 18.00-18.30 Dystonia and rehabilitation Daniele Volpe 18.30-19.00 General Discussion 19.00-20.00 Welcome Cocktail

Thursday - June 5 th, 2014 Session 2 Maladaptive plasticity in PD: the cases of impulse control disorders (ICDs) and dyskinesia Chairs: 8.30-9.30 Main Lecture Habits, rituals and the basal ganglia Ann Graybiel 9.30-10.00 ICDs and plasticity: an overview Pietro Pietrini 10.00-10.30 ICDs in PD Melissa Nirenberg 10.30-11.00 Coffee break 11.00-11.30 Dyskinesia animal models Angela Cenci 11.30-12.00 Dyskinesia in human PD: insight from TMS studies Asha Kishore 12.00-12.30 General discussion 12.30-14.30 Buffet Lunch + Poster session I

Thursday - June 5 th, 2014 Session 3 Cerebellar plasticity and movement disorders Chairs:.. 14.30-15.30 Main Lecture The connections between cerebellum and basal ganglia Angelo Quartarone 15.30-16.00 Cerebellar plasticity and its contribution to motor learning Christiaan I. De Zeeuw 16.00-16.30 TMS: a tool for inducing cerebellar plasticity in humans? Giacomo Koch 16.30-17.00 Coffee Break 17.00-17.30 Cerebellum and dystonia HA Jinnah 17.30-18.00 Cerebellum and PD Mark Hallet 18.00-18.30 General Discussion

Friday - June 6 th, 2014 Session 4 Basic mechanisms and measures of structural plasticity Chairs: 8.30-9.30 Main Lecture The fantastic plastic brain: basic mechanisms of structural plasticity Randolph J. Nudo 9.30-10.00 Watching the synaptic brain landscape changing in alive animals Chiara Cirelli 10.00-10.30 How to explore structural plasticity in humans Yaniv Assaf 10.30-11.00 Coffee break 11.00-11.30 Genetics, epigenetics and brain plasticity Jean Antoine Girault 11.30-12.00 Structural plasticity in neurological diseases Matilde Inglese 12.00-12.30 General discussion 12.30-14.30 Buffet Lunch + Poster session II

Friday - June 6 th, 2014 Session 5 Neurooncology and plasticity Chairs: 14.30-15.30 Main Lecture Brain hodotopy: from basic science concepts to surgical applications - a TMS study Hugues Duffau 15.30-16.00 Cortico-cortical connectivity in brain tumors: TMS and MEG studies Paolo Maria Rossini 16.00-16.30 Reorganization of motor map in patients after brain tumor excision: ntms approach Vincenzo Rizzo 16.30-17.00 Longitudinal MR imaging in patients with gliomas: a combined DTI and fmri approach Alberto Bizzi 17.00-17.30 General Discussion 17.30-18.30 Highlights and final remarks Mark Hallet 18.30-20.00 Visit to the Castle and refreshment 20.45 Social Dinner

GENERAL INFORMATION Congress Venue: Eolian Hotel Milazzo Salita dei Cappuccini, 21/23 98057 Milazzo (Me) Tel +39 0909221992 Fax +39 0909240099 Mail info@eolianmilazzohotel.it Official Language: The Workshop will be conducted in English. Certificates of Attendance: Certificates of attendance will be available on request at the end of the Workshop at the Registration Desk. PCO in charge: ADM Congressi S.r.l. Via F. Crispi, 4-98121 Messina Italy Telephone +39 090345281 (ext. 7) Fax +39 09047044 E-mail info@admcongressi.it