Sponsorship and Exhibition Prospectus. Controversies in Psychiatry. World Congress on. Berlin, Germany, June 17-20, 2010 Invitation to Industry

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The Academy for Clinical Debates & Controversies in Medicine World Congress on Controversies in Psychiatry Berlin, Germany, June 17-20, 2010 Invitation to Industry Sponsorship and Exhibition Prospectus A comprehensive Congress fully devoted to clinical debates and controversial issues in a wide spectrum of psychiatric conditions www.comtecmed.com/copsy

2 Berlin, Germany - June 17-20, 2010 Dear Friends and Colleagues, We take pleasure in inviting you to take part in The First World Congress on Controversies in Psychiatry (COPSY). We would be honored by your participation. During the Decade of the Brain, the field of Psychiatry has witnessed enormous expansion in clinical and basic data. This growth has created a greater need to debate the many controversial issues raised and translate them into clinical practice. This point is emphasized in light of the creation of the Neurosciences and the need to negotiate a unique place for Psychiatry in this domain. This is a Concept Congress that strives to promote true clinical discussion on unresolved pressing issues between practicing physicians and clinical researchers and allowing ample time for speakers-audience interaction. This CME approved Congress has the ability to reach real-life agreed-upon insights on a wide range of psychiatric issues even when the available data is incomplete. The Congress will highlight up-to-date, evidence-based medicine in Psychiatry, to be presented by internationally acclaimed experts. We look forward to your positive response. Your presence will create a greater forum dedicated to solving these controversial issues. Yours sincerely, Prof. Meir Steiner Prof. Julien Mendlewicz Prof. Joseph Zohar On behalf of the international Scientific Committee International Scientific Committee Meir Steiner, MD, PhD, FRCPC, Canada, Chairman Professor of Psychiatry & Behavioural Neurosciences and Obstetrics & Gynecology, McMaster University Professor, Department of Psychiatry and Institute of Medical Sciences Adjunct Scientist,,The Hospital for Sick Children, Toronto Founding Director, Women's Health Concerns Clinic St. Joseph's Healthcare Hamilton Julien Mendlewicz, MD, Ph.D, Belgium, Chairman Professor of Psychiatry, Free University of Brussels (President of the European College of Neuropsychopharmacology (ECNP Secretary General of the European Brain Council Joseph Zohar, MD, Israel, Chairman Director of Psychiatry A and Anxiety Clinic, Chaim Sheba Medical Center Professor of Psychiatry, Tel Aviv University Cyril Höschl, DrSc., FRCPsych., Czech Republic, Member President, European Psychiatric Association Director, Prague Psychiatric Centre affiliated with Charles University Prof. Dr. med. Hans-Jürgen Möller, Germany, Member Director Clinic for Psychiatry of the University of Munich Ludwigs-Maximilians Universität München Nussbaumstrasse, Munich Siegfried Kasper, MD, Austria, Member Department of Psychiatry and Psychotherapy Medical University Vienna, Wien

Berlin, Germany - June 17-20, 2010 3 Sections: Bipolar Disorders Head Guy Goodwin, MD, Ph.D., UK W.A.Handley Professor of Psychiatry Head, University Department, Warneford Hospital, Oxford Anxiety Disorders Head Eric Hollander, MD, USA Esther and Joseph Klingenstein Professor and Chair of Psychiatry Director, Seaver and NY Autism Center of Excellence Mount Sinai School of Medicine Women s Mental Health Head Susan G. Kornstein, MD, USA Professor of Psychiatry and Obstetrics and Gynecology, Virginia Commonwealth University Executive Director, VCU Institute for Women's Health President, International Association for Women's Mental Health Editor-in-Chief, Journal of Women's Health Members P. Blier, Canada E. Vieta, Spain L. Von Knorring, Sweden Members B. Bandelow, Germany B. Baldwin, UK D.J. Stein, South Africa Members A. Clayton, USA L. Cohen, USA Z. Dolev, Israel E. Eriksson, Sweden T. Pearlstein, USA C. Soares, Canada Local Organizing Committee Head Isabella Heuser, MD, Germany Professor of Psychiatry Chair of Psychiatry at the Medical School of the Charité Berlin Director of the Clinical and Research Unit of Psychiatry, Hospital Charité Berlin Members I. Anghelescu, Germany M. Bajbouj, Germany M. Huell, Germany G. Kronenberg, Germany A. M. Lindenberg, Germany D. Naber, Germany R. Rupprecht, Germany H.U. Wittchen, Germany

4 Berlin, Germany - June 17-20, 2010 Preliminary Program BIPOLAR DISORDERS PHENOTYPIC DIFFERENTIATION The boundaries of bipolar disorders are not well defined. Is it a single nosologic entity or a cluster of different syndromes? Bipolar disorder: Spectrum or nonspectrum? Early onset bipolar disorder - how does it differ from the late onset form? Brain imaging as a diagnostic and therapeutic tool Childhood Bipolar Disorder: Myth or Reality? Myth: The diagnosis of childhood bipolar disorder and its very existence is being questioned Reality: New studies indicate that childhood bipolar disorder is a real entity How to differentiate bipolar disorder from attention deficient hyperactiviy disorder (ADHD) in children? THERAPEUTIC INTERVENTIONS IN BIPOLAR DISORDERS (1) Various pharmacological approaches are available, but the complexity of bipolar disease renders optimal treatments problematic. What is the ideal mood stabilizer? Should we use second-generation antipsychotics as mood stabilizers? Should we use anti-epileptics as mood stabilizers? Individualised treatment: Is pharmacogenetics a reality or fantasy? THERAPEUTIC INTERVENTIONS IN BIPOLAR DISORDERS (2) Despite polypharmacy relapses of bipolar disease are frequent USA versus European guidelines for the treatment of bipolar disorder The place for psychosocial therapies Antidepressants Aggravate Bipolar Disorders Yes: No: Proposition: Should bipolar depression be treated differently from unipolar depression? Opposition: Bipolar and unipolar depressions should be treated similarly! UNIPOLAR DISORDERS PREDICTION OF TREATMENT-RESISTANT DEPRESSION (TRD) Approximately one-third of patients suffering from depression do not respond to adequate antidepressant treatment - can this be predicted? What are the predictors of TRD and how should it be managed? How should TRD be best defined? What are the clinical and neurobiological predictors? Therapeutic challenges of TRD Can we optimize achieving remission in depression? THE COMORBIDITY PUZZLE OF DEPRESSIVE DISORDERS The great majority of depressed patients suffer from other psychiatric and somatic disorders as well. Why is diagnosis so important? Psychiatric comorbidity Somatic comorbidity Therapeutic challenges of comorbid depression

Berlin, Germany - June 17-20, 2010 5 NOVEL APPROACHES TO TREATMENT OF DEPRESSION (I) Despite pharmacological advances, there is still a need to improve efficacy and tolerance of antidepressant therapies What is the place for novel antipsychotic drugs? Do antiepileptic drugs have a place in the treatment of depression? Chronopharmacological and chronobiological approaches - how strong is the evidence? NOVEL APPROACHES TO TREATMENT OF DEPRESSION (II) Despite pharmacological advances, there is still a need to improve efficacy and tolerance of antidepressant therapies Nonpharmacological approaches - do they still have a place? Monotherapy or Combination Therapy? Proposition: Combination therapy acts faster and more efficiently than monotherapy Opposition: Start with monotherapy then add! ANXIETY DISORDERS PREVENTION IN POSTTRAUMATIC STRESS DISORDER (PTSD) AN ILLUSION OR A DREAM COME TRUE? Can the well-accepted notion of "golden hours" (very early intervention which alters the course, e.g. in CVA etc.) be adopted in psychiatry and in the treatment of PTSD? Can PTSD be Prevented? Proposition: Insights gained from neuroscience suggest that early intervention may prevent PTSD Opposition: The emotional response to trauma is a normal response to an abnormal situation and no special intervention is needed In the aftermath of trauma exposure, what are the positive and negative procedures? COGNITIVE-BEHAVIORAL THERAPY (CBT) REVISITED Several guidelines (e.g. NICE) suggest CBT as a first-line option in treatment of anxiety disorders, and plummets pharmaceutical intervention to second place Can CBT Replace Psychopharmacological Therapy in Anxiety Disorders? Proposition: Should CBT be a first-line treatment in anxiety disorders? Opposition: Should psychopharmacological treatment remain a first-line treatment in anxiety disorders? Neuroscience, CBT and psychopharmacology: Can the treatment be tailored? ANXIETY DISORDERS TOWARD DSM-V AND ICD-11 WHAT WILL REMAIN AND WHAT WILL CHANGE Traditionally, anxiety disorders have been grouped together based on symptomatic presentation of "anxiety" Should Obsessive Compulsive Disorder (OCD) and Generalized Anxiety Disorders (GAD) Remain in Anxiety Disorders? Proposition: The data is not strong enough for radical changes Opposition: Neuroscience, epidemiological and genetic findings support division of anxiety disorders The concept of anxiety spectrums Stress-related disorders

6 Berlin, Germany - June 17-20, 2010 TREATMENT RESISTANCE Treatment-resistant patients require more time in clinics and treatment remains controversial Switching vs. Augmentation Proposition: Clinical and theoretical background favours "switching" Opposition: Evidence and the "myths" of augmentation Treatment tailored to a specific patient CURRENT USE OF BENZODIAZEPINES (BNZ) BNZ have been widely used, but concern has also been raised regarding tolerance and withdrawal BNZ for Anxiety Why are They Coming Back? Proposition: We should keep using BNZ! Opposition: BNZ be abandoned! BNZ, half-life and addiction potential SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIs) AND TRICYCLIC ANTIDEPRESSANTS (TCA) A SECOND LOOK Clinical experience with the use of TCA is diminishing - however, relinquishment may be too early Does TCA Play a Role in Modern Psychiatric Treatment? Proposition: Despite diminishing experience, TCAs are still relevant for treatment Opposition: TCAs should be disposed of and should be replaced by SSRIs The practicality of TCA use WOMEN S MENTAL HEALTH ANTIDEPRESSANT USE DURING PREGNANCY AND BREASTFEEDING Despite accumulating data suggesting the relative safety of antidepressants during the perinatal period, many clinicians are still reluctant to prescribe them Are antidepressants given during the perinatal period safe? Yes: No: Do safety issues differ in early or late pregnancy? What are the potential risks to the fetus and the newborn? How can a clinician make the best evidence-based, risk-benefit decision? GENDER AND DEPRESSION Evidence on gender differences in symptoms, prevention and treatment of depression is accumulating Does Female Depression Differ from Male Depression? Yes: No: Do clinical parameters for diagnosis, prevention and treatment vary? Are new diagnostic female-specific tools reliable? (biomarkers) Is the reproductive state important for treatment and diagnosis?

Berlin, Germany - June 17-20, 2010 7 : : PRESCRIBING HORMONE REPLACEMENT THERAPY (HRT) DURING MENOPAUSAL TRANSITION Re-evaluation of Women s Health Initiative (WHI) data on a subset of early menopausal women indicates that the benefits outweigh the risks! HRT has no Place in the Treatment of Depression During Perimenopause Yes: HRT has no place in the treatment of perimenopausal women No: Trial of treatment with HRT can be an important tool in overcoming perimenopausal symptoms Putting WHI results in perspective Are all HRT similar? Are estrogens alone safer and more effective? For which indication? Should we limit the treatment to early menopause? Short-term or long-term treatment? Alternatives to HRT - are they at all effective? Should psychiatrists refrain from prescribing HRT? PERINATAL PSYCHIATRIC DISORDERS The uniqueness of Perinatal Psychiatric Disorders (PPD) is being invalidated by the APA based on the diagnostic system, but continues to be endorsed by most psychiatrists in other countries Are PPD unique? Yes: No: TREATMENT CHOICES FOR PREMENSTRUAL SYNDROMES (PMS/PMDD) Despite the established efficacy of (SSRIs) and (SNRIs) in the treatment of PMDD their use is not universally accepted Should antidepressants be prescribed routinely for women with premenstrual complaints? Pros: Cons: Clinical issues in prescribing for PMS/PMDD Are hormonal therapies an option? Should the SSRIs/SNRIs be prescribed continuously, or intermittently (during the late luteal phase only)? How long does a responder need to stay on the medication? Is there any evidence that herbal/alternative treatments work? OTHER TOPICS DEMENTIA The value of sub-classification and the mode of treatment of the various types of dementia (like Mild Cognitive Impairment (MIC), Alzheimer, Vascular Dementia, Lobar Dementia, Lewis Body disease (LB) dementia) are still controversial Proposition: Sub-classification of dementia has no therapeutic impact and hence is not needed Opposition: Sub-classification of dementia is important clinically and therapeutically Should demented - agitated or psychotic patients be treated with antipsychotic drugs and if so, for how long? SCHIZOPHRENIA Schizophrenia is one of the most common psychiatric diseases yet many questions are still unanswered! Are Second Generation Antipsychotics (SGA) better than First Generation Antipsychotics (FGA)? Is identification and RX treatment of pordoromal symptoms in schizophrenia possible and justified? Can cognitive impairment in schizophrenia be characterized and treated? Is administration of 2 antipsychotics ever justified?

8 Berlin, Germany - June 17-20, 2010 Sponsorship Opportunity List As outlined below, there are a number of opportunities for sponsorship available. In addition to the individual benefits of each package, all sponsors will be acknowledged on the Congress Website and in the final Congress Program. If you are interested in any of the sponsorship opportunities below, please contact the Congress Organizer Continuing Medical Education (CME) Approved Symposium 30,000 Euro The Sponsor may provide a grant to support an existing session or suggest a CME-approved session (1.5-2 hours) as part of the Scientific Program. The expenses of the Symposium s chairpersons and speakers (registration, accommodation and travel) will be the responsibility of the Sponsor. Symposium hall and standard audio/visual equipment Four complimentary registrations (for symposium chairpersons and speakers) A 100-word sponsor/product profile will be published in the final Congress Program Approximately 12 sq.m exhibition space Additional space may be obtained at a special, reduced price of 400 Euro per sq.m Two complimentary registrations for exhibitors. Additional exhibitor s registration may be purchased at 350 Euro per person One A4 page advertisement, full color, published in the final Congress Program The Sponsor's logo will be published on the Congress Website, providing a two-way link The Sponsor's brochure will be inserted in the participants' bags Satellite Symposium (NON-CME APPROVED) 40,000 Euro The Sponsor may organize an industrial non-cme Satellite Symposium (1.5-2 hours) as part of the Scientific Program. Organizing Committee approval of the content and speakers is required. Date and time of the Symposium will be mutually agreed upon. The expenses of the Symposium s chairpersons and speakers (registration, accommodation and travel) will be the responsibility of the Sponsor. Symposium hall and standard audio/visual equipment Five complimentary registrations (for Symposium chairpersons and speakers) A 100-word sponsor/product profile will be published in the final Congress Program Approximately 16 sq.m exhibition space Additional space may be obtained at a special, reduced price of 400 Euro per sq.m Two complimentary registrations for exhibitors. Additional exhibitor s registration may be purchased at 350 Euro per person One A4 page advertisement, full color, published in the final Congress Program The Sponsor's logo will be published on the Congress Website providing a two-way link The Sponsor's brochure will be inserted in the participants bags

Berlin, Germany - June 17-20, 2010 9 PRE/POST-Congress Satellite Symposium (NON-CME APPROVED) 50,000 Euro (This option is particularly suited for drug launching and other special events) The Sponsor may organize an industrial non-cme approved Pre/Post-Congress Satellite Symposium, for 3-4 hours (or more) on Thursday (June 18th, 2009), just before the official opening of the Congress, or at the end (June 21st, 2009) of the Congress. The expenses of the Symposium s chairpersons and speakers (registration, accommodation and travel) will be the responsibility of the Sponsor. Symposium hall and standard audio/visual equipment Six complimentary registrations (for symposium chairpersons and speakers) A 100-word sponsor/product profile will be published in the final Congress Program Approximately 20 sq.m exhibition space Additional space may be obtained at a special, reduced price of 400 Euro per sq.m Two complimentary registrations for exhibitors. Additional exhibitor's registration may be purchased at 350 Euro per person One A4 page advertisement, full color, published in the final Congress Program The Sponsor's logo will be published on the Congress Website, providing a two-way link The Sponsor's brochure will be inserted in the participants bags LUNCH (per lunch) 25,000 Euro The Sponsor may subsidize 'in part' a buffet lunch served on Friday, (June 19th, 2009) and/or on Saturday (June 20th, 2009). Four complimentary registrations (for the Sponsor s staff) The Sponsor's logo will appear on a special board at the Lunch venue A 100-word sponsor/product profile will be published in the final Congress Program An A4 half-page advertisement, full color, published in the final Congress Program The Sponsor's logo will be published on the Congress Website providing a two-way link The Sponsor s brochure will be inserted in the participants' bags Lunch Symposium (NON-CME APPROVED) 40,000 Euro The Sponsor may organize an industrial CME Lunch-tailored Symposium, for up to one hour as part of the Scientific Program. Please contact the Congress Organizer to coordinate the details.

10 Berlin, Germany - June 17-20, 2010 Other Sponsorship Opportunities In addition to the major sponsorship opportunities, a range of other sponsorship packages is available to meet various needs. Welcome Reception: Sole Sponsorship 20,000 Euro A Welcome Reception for all participants will be held on Thursday evening at the Congress venue. The Sponsor s logo will appear on a special board at the Welcome Reception venue A 100-word sponsor/product profile will be published in the final Congress Program An A4 half-page advertisement, full color, published in the final Congress Program The Sponsor s brochure will be inserted in the participants' bags Congress Program: Sole Sponsorship 15,000 Euro The final Congress Program will include the Scientific Program of the Congress. The Congress Program will be distributed to all participants and will be an invaluable reference book after the Congress One A4 page advertisement, full color, published on the back cover of the final Congress Program A 100-word sponsor/product profile will be published in the final Congress Program The Sponsor's logo will be published on the Congress Website providing a two-way link

Berlin, Germany - June 17-20, 2010 11 Faculty Dinner: Sole Sponsorship 10,000 Euro A Faculty Dinner will be held for the invited speakers of the Congress. The Sponsor s logo will appear on a special board at the Faculty Dinner venue Internet Café: Sole Sponsorship 10,000 Euro The Sponsor will provide workstations and technical assistance in the Internet Cafe Display Sponsor logo/information on screensaver Display Sponsor logo/information on screen background Distribute mouse pads and related promotional gifts at the cyber center Participant Bags: Sole Sponsorship 10,000 Euro The sponsor is asked to kindly provide the participants bags for the Congress themselves. The bags will be distributed to each participant of the Congress. The Sponsor's brochure/s will be inserted in the participants' bags The Sponsor's logo will be published on the Congress Website, providing a two-way link CD-ROM 10,000 Euro The CD-ROM will contain all of the COPSy Congress abstracts and will be distributed to all the participants from the Sponsor s exhibition booth. An exchange voucher (printed by the Sponsor) will be placed in the Congress kit. Exclusive advertisement on the cover of the voucher Exclusive advertisement on the cover of the CD-ROM cover. Mini Program: Sole Sponsorship 5,000 Euro A pocket-size Program together with their registration bags will be distributed to all participants. The Sponsor s exclusive advertisement on the back cover of the Mini Program The Sponsor's logo will be published on the Congress Website, providing a two-way link

12 Berlin, Germany - June 17-20, 2010 Translation from English 5,000 Euro Simultaneous Translation from English to any required language (Cost per hall per day) The Sponsor s logo will appear on a special board in the hall The Sponsor's logo will be published on the Congress Website, providing a two-way link Congress Lanyard: Sole Sponsorship The Sponsor provides printed lanyards for the name badges Congress provides the printed lanyards for the name badges 3,000 Euro 6,000 Euro The Sponsor/product name, logo or text printed on lanyards European speaker: 3,000 Euro The Sponsor may support in part the expenses of one or more invited European Speaker. Expenses include registration, accommodation and travel. A half-page advertisement, full color, will be published in the final Congress Program The Sponsor will be acknowledged in the final Congress Program, and the Sponsor s logo will appear on a separate Sponsor Logo page Non-european speaker: 6,000 Euro The Sponsor may support in part the expenses of one or more invited Non-European Speaker. Expenses include registration, accommodation and travel. An A4 half-page advertisement, full color, will be published in the final Congress Program The Sponsor s brochure will be inserted in the participants bags The Sponsor will be acknowledged in the final Congress Program, and the Sponsor s logo will appear on a separate Sponsor Logo page Prizes for Outstanding Abstracts 3,000 Euro Six prizes of 500 Euro each will be presented to six of the most outstanding abstracts/posters. This will be announced before the congress, on the Website and to all the participants. The Sponsor s representative will be invited to attend the prize giving

Berlin, Germany - June 17-20, 2010 13 Writing Pads and Pens 3,000 Euro The Sponsor will provide the participants notepads and pens. This can be an effective high-profile sponsorship opportunity for a drug launch or for immediate brand recognition. The notepads and pens will bear the sponsor's company product/logo and will be distributed in the Congress bags. Brochure Insert 3,000 Euro Based on the specifications of the sponsor, a brochure will be inserted in the Congress bag. The bag will be distributed to all of the participants of the Congress.

14 Berlin, Germany - June 17-20, 2010 General Information Venue Berlin, Germany Congress Organizer Congress Organizers and Secretariat ComtecMed 53 Rothschild Blvd. PO Box 68, Tel Aviv 61000, Israel Tel: 972-3-5666166 Fax: 972-3-5666177 Email: copsy@comtecmed.com Liability and Insurance The organizer is not liable whatsoever for injuries or damages involving persons and/or property during the Congress. Participants are advised to issue their own personal travel and health insurance for their trip. Language The official language of the Congress is English. Sponsorship and Exhibition ComtecMed c/o Lina Deshilton 53 Rothschild Boulevard, PO Box 68 Tel Aviv, 61000, Israel Tel: +972 3 5666166 Fax: +972 3 5666177 Email:lina@comtecint.com Website: www.comtecmed.com/copsy A professional exhibition will be held at the Venue in conjunction with the Congress. The floor plan has been designed so as to maximize the exhibitors exposure to the delegates. Coffee breaks will be held in this exhibition area. Exhibition spaces will be released for general sale six months prior to the opening date of the Congress. Prior to this date, sponsors will have exclusive rights for space selection. Registration Participants Physicians & scientists Early Registration Until January 1, 2010 Late Registration After January 1, 2010 From June 13, 2010 and on site 540 Euro 590 Euro 650 Euro Residents* 320 Euro 380 Euro 420 Euro Accompanying Persons 140 Euro *Refers to non-tenured junior scientists. Registration form must be accompanied by documentation of residency or a letter from the head of department confirming their status. The letter should be on the department letterhead and addressed to the Registration Department of the Congress. Registration includes: Participation in scientific sessions, Congress bag, Program and Abstract Book, all printed material of the Congress, invitation to the Get-Together Reception, coffee breaks, lunch on Friday and Saturday. Special Group Registration Policy is available upon request. Accommodation We have managed to book the best available allocation in major hotels in Berlin that will enable us to comply with all of your future accommodation requests. We have negotiated the best available special group rates for the companies. If your company is interested in booking hotel accommodation ComtecMed will be pleased to negotiate the rates and allocation for you. Liability and Insurance The organizer carries no liability whatsoever for injuries or damages involving persons and/or property during the Congress. Participants are advised to issue their own personal travel and health insurance for their trip.

Berlin, Germany - June 17-20, 2010 15 Sponsorship Booking Form ComtecMed Medical Congresses Fax: +972 3 5666177 53 Rothschild Boulevard Tel: +972 3 5666166 P.O. Box 58 Email: copsy@comtecmed.com Tel Aviv 61000, Israel Website: www.comtecmed.com/copsy Contact Name Company Name Address Post/Zip Code Telephone Email Country Fax Website I would like to book the following Sponsorship items: Sponsorship item Pre-Congress Satellite Symposium Package Lunch Symposium Satellite Symposium Package CME-Approved Symposium Package Lunch Welcome Reception Congress Program Book CD-ROM Faculty Dinner Internet Café Participants Bags Congress Lanyards European Speaker Non-European Speaker Mini/Pocket Program Translation from English Writing Pads and Pens Brochure Insert Prizes for Outstanding Abstracts Price 50,000 Euro 40,000 Euro 40,000 Euro 30,000 Euro 25,000 Euro 20,000 Euro 15,000 Euro 10,000 Euro 10,000 Euro 10,000 Euro 10,000 Euro 6,000 or 3,000 Euro 3,000 Euro 6,000 Euro 5,000 Euro 5,000 Euro 5,000 Euro 3,000 Euro 3,000 Euro I would like to book Exhibition space: Sponsor Booth at 400 Euro per sq.m (Minimum Booth Size: 5x3 sq.m) Non-Sponsor Booth at 800 Euro per sq.m (Minimum Booth Size: 5x3 sq.m) Please call me to discuss the sponsorship package Please send me a sponsorship contract and first 50% deposit invoice. Signature Date

Berlin Headquarters and Administration 53 Rothschild Boulevard PO Box 68, 61000 Tel Aviv, Israel Tel. +972-3-5666166 Fax.+ 972-3-5666177 Email: info@comtecmed.com Comtec Spain Bailén, 95-97, pral.1.a 08009 Barcelona, Spain Tel. +34-93-2084445 Fax. +34-93-4579291 Email: spain@comtecmed.com Comtec China 175 Xiang Yang Road South, Shanghai 200031, China Tel. +86-21-54660460 Fax. +86-21-54660450 Email: china@comtecmed.com www.comtecmed.com/copsy copsy@comtecmed.com