Everyday Relief. Everyday Protection.

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Everyday Relief. Everyday Protection. CLINICAL RESULTS ON BACK! A Targeted Approach to Practice Building! Treats Sensitivity Soothes & Moisturizes Dry Mouth Tissues Helps to Prevent Caries & Gingivitis

Target! Sensitivity Enamelon Preventive Treatment Gel: Builds increasing protection and relief from sensitivity by occluding tubules with fluoride and ACP - 5000 ppm F toothpaste not indicated for sensitivity (unless containing Potassium Nitrate) - Sensitivity toothpaste with Potassium Nitrate provides a chemical masking agent. PRACTICE BUILDER - Ask your patients about sensitivity For both immediate and extended relief, apply in-office varnish and provide Enamelon Preventive Treatment Gel for daily home use. - Insurance code D9910 is appropriate for in-office application of fluoride varnish to treat tooth and root sensitivity. - There is no code for home-use with non-prescription Enamelon. - Narrative should include diagnosis and treatment. PROFIT MODEL - Patients Presenting with Sensitivity

Target! Orthodontic Patients Enamelon Preventive Treatment Gel: Strengthens Enamel - Reduces demineralization and the solubility of enamel 1 - Demineralization can lead to white spot lesions - especially around brackets. Helps to interfere with the harmful effects of plaque associated with gingivitis A one-step solution with a great flavor and mouth feel for increased compliance Safe for all ages 3 PRACTICE BUILDER - Are you missing out on recurring revenue? Keep the business in the office - No Scripts! Recurring in-office revenue; dispense as needed for treatment duration Each patient requires 3-4 tubes per year. - Dispense and bill as part of treatment plan. PROFIT MODEL - New-Start Patients

Target! Pediatric Patients Enamelon Preventive Treatment Gel: Provides more protection with less fluoride 2. - Contains 970 ppm F vs. 5000 ppm F toothpastes to help prevent caries. Safe for all ages, non-abrasive Smaller orifice ensures controlled dispensing. Great flavor - the sweet vanilla notes calm the mint flavor for improved compliance. PRACTICE BUILDER New revenue for patients under age 6* - Many fluoride therapies are contraindicated for children of these ages. - Enamelon has a low level of fluoride (970 ppm F) and demonstrated efficacious results. Now secure revenue for at-risk patients ages 6-18 - No more scripts for 5000 ppm F Designed for Children s Safety * Smear amount (0.125 g) Up to age 3 Pea-size amount (0.25 g) Ages 3 to 6 PROFIT MODEL - Pediatric Patient Hygiene Visits (ages up to 18) Enamelon offers a reduced-sized orifice so patients - and care-givers - easily can control dispensing.

Target! Periodontal Patients Enamelon Preventive Treatment Gel: Helps to prevent gingivitis Provides relief from sensitivity by delivering ACP and stannous fluoride to occlude tubules. Protects against caries - especially helpful for patients with exposed root surfaces. Soothes and moisturizes discomfort associated with dry mouth tissues. Includes stannous fluoride to inhibit bacterial adhesion and growth. Non-abrasive No SLS PROFIT MODEL - Patients Presenting with Periodontal Issues PRACTICE BUILDER Keep the business in the office - No 5000 ppm F scripts. Target Scaling and Root-planing patients (SRP). Target pre- and post-surgical patients. Target patients with sensitivity.

Target! 5000 ppm F Toothpastes Practice Builder Enamelon is non-prescription and can be dispensed at the office - No need to write a script! No worries about substitution.

General Profit Model Patient Usage Use Enamelon Preventive Treatment Gel once a day after brushing with a toothpaste. Alternatively, many oral health-care professionals recommend brushing in the morning with their everyday toothpaste and in the evening with Enamelon.

New Standard of Caring Everyday Relief. Everyday Protection. Treats sensitivity Relieves the discomfort of dry mouth tissues Helps to prevent caries & gingivitis Non-irritating to patients with dry mouth Contains no SLS, gluten or dyes 0.40% stabilized stannous fluoride (970 ppm F) Optimized with calcium and phosphate ions Non-abrasive formula for daily use Safe for patients of all ages 3 Premier Dental Products Company 1710 Romano Drive, Plymouth Meeting, PA 19462, U.S.A. Phone 888-670-6100 610-239-6000 Fax 610-239-6171 www.premusa.com E-mail: dentalinfo@premusa.com 90% 95% 75% Clinical Results! 4 of dentists indicated that their patients experienced a reduction in generalized tooth sensitivity using Enamelon treatment gel. of dentists indicated they would incorporate Enamelon into their practices and offer it to their patients. of dentists indicated their patients experienced some type of prolonged fresh, smooth, slick feel in their mouths after using Enamelon. Patient Acceptance! 86% of patients are likely to recommend to a friend. 5 1. Schemehorn BR, DiMarino JC, Movahed N. Comparison of the Enamel Solubility Reduction from Various Prescription and OTC Fluoride Toothpastes and Gels. Journal of Clinical Dentistry, 2014;25:61-4. / 2. Schemehorn BR, DiMarino JC, Movahed N. Comparison of the Incipient Lesion Enamel Fluoride Uptake from Various Prescription and OTC Fluoride Toothpastes and Gels. Journal of Clinical Dentistry, 2014;25:57 60. / 3. Dose based on age. / 4. Comisi DDS.,MAGD, John C., The Catapult Group presents its review on this unique, protective, remineralizing and moisture-enhancing preventive treatment gel, Dental Product Report, 2015, October; Issue 10 Vol. 9 :68-69 / 5. Data on File / United States Patent Numbers: US 5,993,784, US 5,711,936, US 5,651,959 and other patents pending. Made in U.S.A. / Ultramulsion is a registered trademark of WhiteHill Oral Technologies, Inc. 93% of patients rated the taste of Enamelon as pleasant. 5 8698747 121519 Rev3