Cognitive Assessment 4/29/2015. Learning Objectives To be able to:

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Supporting the Desire to Age in Place: Important Considerations for the Aging Population AGENDA 8:45 9:00 AM Geriatric Principles Robert L. Kane, MD *9:00 9:55 AM Cognitive Assessments Ed Ratner, MD 10:00 10:55 AM Functional Assessments Terrianne Jones, PhD, OTR/L 11:00 11:55 AM Advance Care Planning Phyllis Greenberg, PhD, MPA Patricia Bresser, PhD, RN 11:55 Noon Wrap Up Tom Hyder, Exec. Dir., MGS Handouts available at mngero.org Sponsored by: Supported by: Cognitive Assessment Edward Ratner, MD Associate Professor of Medicine University of Minnesota Center on Aging Minnesota Area Geriatric Education Center ratne001@umn.edu May 1, 2015 Learning Objectives To be able to: Explain the difference between screening for dementia and assessment of cognitive function Describe differences between the Orientation assessment, Mini-Cog, MMSE,, and SLUMS tools Correctly document cognition in a medical record 1

Cognitive Domains (per DSM-5) Complex attention (managing distractions) Executive function (decision-making) Learning and memory (repeating things) Language (expressive or receptive) Perceptual-motor (use of tools) Social cognition (recognizing emotions) Note: knowledge is not a domain of cognition DSM 5 Definition of Neurocognitive Disorder Diagnostic Statistical Manual 5 th Edition 2013 Neurocognitive Disorder replaced Dementia Expanded population included Reduced misunderstanding and reluctance to diagnosis Neurocognitive Disorder What it is NOT Not due to delirium Not due to other mental disorder 2

Neurocognitive Disorder (NCD) a) Mild NCD (similar to Minimal Cognitive Impairment) Moderate Cognitive Decline (one or more domains) NOT Interfering with independence b) Major NCD (similar to dementia) Significant Cognitive Decline (one or more domains) Interfering with independence Severity: mild -iadl difficulty, moderate -ADL difficulty severe - fully dependent Scope of NCD Affects up to about 5.5 million Americans Prevalence in US % 40 35 30 25 20 15 10 5 0 71-79 80-89 90+ Age Health, long-term care, and hospice care costs were $183 billion in 2011 Comparable to diabetes, much greater than cancer Listed in DSM-5 Causes of NCD Due to Another Medical Condition Alzheimer s Disease Frontotemporal lobar degeneration (ALS) Lewy Body disease Vascular dementia Traumatic Brain injury Substance/medication induced HIV infection Prion Disease (Creutzfeldt-Jacobs) Parkinson s Disease Huntington s disease Normal pressure hydrocephalus Hypoxia Heart failure Autoimmune (lupus) Metabolic (B12 deficiency, liver or kidney disease) Neoplastic (brain tumor) Endocrine (Hypothyroidism) Other infectious diseases (neurosyphillis) Multiple Sclerosis Episodic (seizure, migraine) Due to multiple etiologies 3

Why Assess Cognition Screening Patient (caregivers) without concern High risk (elderly, pre-operative, head trauma) Diagnosis Assessment of Severity / Pattern Treatment planning Monitoring How to Assess Cognition Functional history (patient and family) Cognitive Testing Bed-side tools Observed Functional assessment Neuropsychological testing Environmental (home) assessment Brain imaging Laboratory tests Functional History Related to Cognition What do you do in a typical day? Do you drive, use computer, manage finances? What types of meals do you prepare? What do you read? How often do you leave your home? Do you make phone calls? Who are these people in your family? Where is your room? 4

Functional Assessment Questionnaire Ask informant to rate patient s ability using the following scoring system: Dependent = 3 Requires assistance = 2 Has difficulty but does by self = 1 Normal = 0 Never did [the activity] but could do now = 0 Never did and would have difficulty now = 1 1. Writing checks, paying bills, balancing checkbook 2. Assembling tax records, business affairs, or papers 3. Shopping alone for clothes, household necessities, or groceries 4. Playing a game of skill, working on a hobby 5. Heating water, making a cup of coffee, turning off stove after use 6. Preparing a balanced meal 7. Keeping track of current events 8. Paying attention to, understanding, discussing TV, book, magazine 9. Remembering appointments, family occasions, holidays, 10. medications 11. Traveling out of neighborhood, driving, arranging to take buses Functional Assessment Questionnaire Scoring Sum scores (range 0-30). Cutpoint of 9 (dependent in 3 or more activities) is recommended to indicate impaired function and possible cognitive impairment. Pfeffer RI et al. Measurement of functional activities in older adults in the community. J Gerontol 1982; 37(3):323-329. Reprinted with permission of The Gerontological Society of America, 1030 15th Street NW, Suite 250, Washington, DC 20005 via Copyright Clearance Center, Inc. Tools to Test Cognition Orientation poor predictor of NCD may be useful for level of consciousness Mini-Cog Screen for Screening Standardized screening tools e.g. MMSE,, SLUMS, ALS-CBS 5

Before You Assess Cognition: Normalize and Reassure Now I am going to do some tests of your thinking. This is a routine part of my examination. We do this for everyone. Some parts may seem silly or may be difficult. Mini-Cog Re-state 3 words (e.g. apple, penny, watch) Draw Clock Inside the circle draw the hours of a clock as if a child would draw them Place the hands of the clock to represent the time forty five minutes past ten o clock Recall the three words Mini-Cog Scoring Negative Screen for NCD 3 objects recalled 1-2 objects recalled + able to draw clock correctly Positive Screen for NCD 1-2 objects recalled + unable to draw clock correctly 0 objects recalled 6

Montreal Cognitive Assessment 30 point scale Many domains Adaptable for vision or loss of use of hands Sensitivity is >96% for Alzheimer s Disease. Fewer than 4/100 with Alz. disease (cutoff >26) Specificity 35%-87% for Alz. Disease (cutoff > 26) Many to most of those without Alz. disease fail Adjust scoring for age, education Domains in Cognitive Assessment DSM-5 vs. Cognitive Domains (DSM-5) Complex attention Executive function Learning and memory Language Perceptual-motor Social cognition Montreal Cognitive Assessment Visual spatial/executive Naming Memory Attention Language Abstraction Delayed Recall Orientation ~Mocatest.org Advantages of vs. MMSE and SLUMS Tools Free Includes executive function Clear instructions available www.mocatest.org 7

Visuospatial/Executive Naming Memory (immediate) 8

Attention Language and Abstraction Delayed Recall 9

Orientation Documentation of Cognition Should be part of comprehensive assessment on admission and discharge to every health care program/setting Document whenever changes in cognition occur Document details Copy of tool Score on each subscale Current functional abilities/disabilities Documentation of Cognition AVOID: Alert and oriented Confused Summary score of tests (e.g. 24/30) 10

What if Positive Screening for NCD Cognitive Performance Assessment Further testing for specific diagnosis Monitoring for progression/improvement Education for: Coping (patient and caregivers) Planning for future Pharmacological and non-pharmacological treatments Collaborative Care Cognitive Performance Test (CPT) Six common activities of daily living (ADL) tasks e.g. DRESS, SHOP, TOAST, PHONE, WASH and TRAVEL Standardized performance and scoring (usually OT) Used to predict level of supervision required ~Burns, J Geriatr Psychiatry Neurol. 1994 Neuropsychology Testing Detailed assessment of many domains Adapted for patient areas of difficulty Adapted for communication barriers Interpreted relative to various diagnoses At least several hours, up to thousands of dollars 11

Collaborative Care in NCD Physicians Occupational therapy Speech therapy Physical therapy Nursing Social Work Psychology Caregiver Coaching Pharmacy Legal Spiritual care Support and Advocacy groups Summary Cognition is a complex concept Difficulties with cognition are relatively common among elderly Cognitive assessment has a variety of purposes There are a variety of ways to assess cognition Cognitive assessment should be a routine part of care for the elderly Documentation of cognitive assessment should be thorough 12