Sexually Transmitted Disease (STD) Surveillance Report, 2012

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Sexually Transmitted Disease (STD) Surveillance Report, 2012 Minnesota Department of Health STD Surveillance System www.health.state.mn.us/std

Introduction Under Minnesota law, physicians and laboratories must report all laboratory-confirmed cases of chlamydia, gonorrhea, syphilis, and chancroid to the Minnesota Department of Health (MDH) within one working day. The MDH does not maintain statistics for other, nonreportable STDs (ex: herpes, HPV/genital warts). This slide set describes trends in reportable STDs in Minnesota by person, place, and time. Analyses exclude cases reported from federal and private prisons.

Introduction STD surveillance is the systematic collection of data from cases for the purpose of monitoring the frequency and distribution of STDs in a given population. STD surveillance data are used to detect problems, prioritize resources, develop and target interventions, and evaluate the effectiveness of interventions.

Interpreting STD Surveillance Data Factors that impact the completeness and accuracy of STD data include: Level of STD screening by healthcare providers Individual test-seeking behavior Sensitivity of diagnostic tests Compliance with case reporting Completeness of case reporting Timeliness of case reporting Increases and decreases in STD rates can be due to actual changes in disease occurrence and/or changes in one or more of the above factors.

Interpreting STD Surveillance Data The surveillance system only includes cases with a positive laboratory test. Cases diagnosed solely on symptoms are not counted. Previous years data included only cases that had a case report form and a matching lab report. This year s data additionally includes cases that had only a lab report and no corresponding case report form. This has increased the number of unknowns in some variables. Surveillance data represent cases of infection, not individuals. A person with multiple infections in a given year will be counted more than once. Caution is warranted when interpreting changes in STD numbers that can seem disproportionately large when the number of cases is small.

National Context

Chlamydia Rates by State, United States and Outlying Areas, 2011 National Rate = 454.1 per 100,000 population Source: Centers for Disease Control & Prevention, Division of STD Prevention. 2011 Surveillance Slides.

Gonorrhea Rates by State, United States and Outlying Areas, 2011 National Rate = 103.1 per 100,000 population Source: Centers for Disease Control & Prevention, Division of STD Prevention. 2011 Surveillance Slides.

Primary and Secondary Syphilis Rates by State United States and Outlying Areas, 2011 National Rate = 4.5 per 100,000 population Source: Centers for Disease Control & Prevention, Division of STD Prevention. 2011 Surveillance Slides.

Overview of STDs in Minnesota

STDs in Minnesota Rate per 100,000 by Year of Diagnosis, 2002-2012 * P&S = Primary and Secondary

STDs in Minnesota: Number of Cases Reported in 2012 Total of 21,465 STD cases reported to MDH in 2012: 18,048 Chlamydia cases 3,082 Gonorrhea cases 335 Syphilis cases (all stages) 0 Chancroid cases

CHLAMYDIA

Kittson Roseau Marshall Pennington Red Lake Polk Norman Mahnomen Clearwater Lake of the Woods Beltrami Koochiching Itasca St. Louis Lake Cook 2012 Minnesota Chlamydia Rates by County Hubbard Clay Becker Cass Wadena Wilkin Otter Tail Todd Grant Douglas Morrison Benton Big Stone Stevens Pope Stearns Traverse Swift Kandiyohi Murray Pipestone Cottonwood Blue Earth Watonwan Aitkin Carlton Pine Olmsted Winona Rock Nobles Jackson Martin Faribault Freeborn Mower Fillmore Houston Isanti Chippewa Hennepin Ramsey Lac Qui Parle Yellow Medicine McLeod Renville Carver Scott Dakota Sibley Lincoln Lyon Redwood Goodhue Nicollet Rice Le Sueur Wabasha Brown Crow Wing Mille Lacs Kanabec Sherburne Chisago Anoka Wright Meeker Washington Waseca Steele Dodge Rate per 100,000 persons 0-75 76-150 151-300 > 300 City of Minneapolis 927 City of St. Paul 795 Suburban # 250 Greater Minnesota 229 (1,176 cases missing residence information) # 7-county metro area, excluding the cities of Minneapolis and St. Paul

Chlamydia Infections by Residence at Diagnosis Minnesota, 2012 Total Number of Cases = 18,048 Suburban = Seven-county metro area including Anoka, Carver, Dakota, Hennepin (excluding Minneapolis), Ramsey (excluding St. Paul), Scott, and Washington counties. Greater MN = All other Minnesota counties outside the seven-county metro area.

Chlamydia Rates by Gender Minnesota, 2002-2012

Chlamydia Rates by Age Minnesota, 2002-2012

Age-Specific Chlamydia Rates by Gender Minnesota, 2012

Chlamydia Rates by Race/Ethnicity Minnesota, 2002-2012 2012 rates compared with Whites: Black = 11x higher American Indian = 5x higher Asian/PI = 2x higher Hispanic = 3x higher * Persons of Hispanic ethnicity can be of any race.

Chlamydia Rates by Race/Ethnicity Minnesota, 2002-2012 * Persons of Hispanic ethnicity can be of any race.

GONORRHEA

Kittson Roseau Marshall Pennington Red Lake Polk Norman Mahnomen Clearwater Lake of the Woods Beltrami Hubbard Koochiching Itasca St. Louis Lake Cook 2012 Minnesota Gonorrhea Rates by County Clay Becker Cass Crow Wing Wadena Aitkin Carlton Wilkin Otter Tail Todd Pine Grant Douglas Morrison Benton Big Stone Stevens Pope Stearns Isanti Chisago Sherburne Traverse Swift Anoka Kandiyohi Wright Meeker Chippewa Ramsey Lac qui Parle Hennepin McLeod Carver Yellow Medicine Renville Scott Dakota Sibley Lincoln Lyon Redwood Goodhue Nicollet Le Sueur Rice Wabasha Brown Murray Cottonwood Blue Earth Steele Dodge Pipestone Olmsted Winona Watonwan Waseca Mille Lacs Kanabec Washington Rate per 100,000 persons 0-10 11-29 30-100 > 100 City of Minneapolis 280 City of St. Paul 184 Suburban # 41 Greater Minnesota 18 (155 cases missing residence information) # 7-county metro area, excluding the cities of Minneapolis and St. Paul Rock Nobles Jackson Martin Faribault Freeborn Mower Fillmore Houston

Gonorrhea Infections in Minnesota by Residence at Diagnosis, 2012 Total Number of Cases= 3,082 Suburban = Seven-county metro area including Anoka, Carver, Dakota, Hennepin (excluding Minneapolis), Ramsey (excluding St. Paul), Scott, and Washington counties. Greater MN = All other Minnesota counties outside the seven-county metro area.

Gonorrhea Rates by Gender Minnesota, 2002-2012

Gonorrhea Rates by Age Minnesota, 2002-2012

Age-Specific Gonorrhea Rates by Gender Minnesota, 2012

Gonorrhea Rates by Race/Ethnicity Minnesota, 2002-2012 2012 rates compared with Whites: Black = 26x higher American Indian = 8x higher Asian/PI = 0x higher Hispanic = 2x higher * Persons of Hispanic ethnicity can be of any race.

Gonorrhea Rates by Race/Ethnicity Minnesota, 2002-2012 * Persons of Hispanic ethnicity can be of any race.

SYPHILIS

Syphilis Rates by Stage of Diagnosis Minnesota, 2002-2012 * P&S = Primary and Secondary

Kittson Roseau Marshall Pennington Red Lake Polk Norman Mahnomen Clearwater Lake of the Woods Beltrami Koochiching Itasca St. Louis Lake Cook 2012 Minnesota Primary & Secondary Syphilis Rates by County Hubbard Clay Becker Cass Crow Wing Wadena Aitkin Carlton Wilkin Otter Tail Todd Pine Grant Douglas Morrison Kanabec Stevens Benton Pope Big Stone Stearns Isanti Sherburne Swift Anoka Kandiyohi Wright Chippewa Meeker Traverse Lac qui Parle Hennepin Ramsey McLeod Carver Yellow Medicine Renville Dakota Scott Sibley Lincoln Lyon Redwood Nicollet Le Sueur Rice Goodhue Wabasha Brown Pipestone Murray Cottonwood Watonwan Blue Earth Steele Waseca Dodge Olmsted Winona Rock Nobles Jackson Martin Faribault Freeborn Mower Fillmore Houston Mille Lacs Chisago Washington Rate per 100,000 persons 0 0.2 0.21 1.0 > 1.0 City of Minneapolis 14.9 (57 cases) City of St. Paul 6.7 (19 cases) Suburban # 1.7 (37 cases) Greater Minnesota 0.2 (5 cases) # 7-county metro area, excluding the cities of Minneapolis and St. Paul

Primary & Secondary Syphilis Infections in Minnesota by Residence at Diagnosis, 2012 Total Number of Cases = 118 Suburban = Seven-county metro area including Anoka, Carver, Dakota, Hennepin (excluding Minneapolis), Ramsey (excluding St. Paul), Scott, and Washington counties. Greater MN = All other Minnesota counties outside the seven-county metro area.

Primary & Secondary Syphilis Rates by Gender Minnesota, 2002-2012

Primary & Secondary Syphilis Rates by Age Minnesota, 2002-2012

Age-Specific Primary & Secondary Syphilis Rates by Gender, Minnesota, 2012

Primary & Secondary Syphilis Cases by Race Minnesota, 2012 Total Number of Cases = 118 *Includes persons reported with more than one race

Primary & Secondary Syphilis Rates by Race/Ethnicity Minnesota, 2002-2012 * Persons of Hispanic ethnicity can be of any race.

CHLAMYDIA AND GONORRHEA AMONG ADOLESCENTS & YOUNG ADULTS (15-19 year olds) (20-24 year olds)

Chlamydia Disproportionately Impacts Youth MN Population in 2010 (n = 5,303,925) Chlamydia Cases in 2012 (n = 18,048)

Gonorrhea Disproportionately Impacts Youth MN Population in 2010 (n = 5,303,925) Gonorrhea Cases in 2012 (n = 3,082)

Chlamydia Rates Among Adolescents & Young Adults by Gender in Minnesota, 2002-2012 Rate=Cases per 100,000 persons based on 2010 U.S. Census counts. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Chlamydia Cases Among Adolescents and Young Adults by Gender and Race, Minnesota, 2012 Males (n = 3,119) Females (n = 9,370) Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Chlamydia Rate Among Adolescents and Young Adults by Race, Minnesota, 2012 Rate=Cases per 100,000 persons based on 2010 U.S. Census counts. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Gonorrhea Rates Among Adolescents & Young Adults by Gender in Minnesota, 2002-2012 Rate=Cases per 100,000 persons based on 2010 U.S. Census counts. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Gonorrhea Cases Among Adolescents and Young Adults by Gender and Race, 2012 Males (n = 618) Females (n = 1192) Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Gonorrhea Rate Among Adolescents and Young Adults by Race, Minnesota, 2012 Rate=Cases per 100,000 persons based on 2010 U.S. Census counts. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Summary of Chlamydia and Gonorrhea Among Adolescents and Young Adults, Minnesota, 2012 Adolescents and young adults accounted for 69% of chlamydia and 65% of gonorrhea cases diagnosed in Minnesota. 74% of chlamydia or gonorrhea cases diagnosed among adolescents and young adults were females. Whites and Blacks accounted for 36% and 30% of chlamydia or gonorrhea cases, respectively. 34% of gonorrhea or chlamydia cases were in the Cities of Minneapolis and Saint Paul. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Topic of Interest: Early Syphilis Among Men Who Have Sex With Men in Minnesota

Number of Early Syphilis Cases by Gender Minnesota, 2002-2012 MSM=Men who have sex with men. Figure does not include cases diagnosed in transgendered persons (1 each in 2004, 2005, 2007, and 2009). Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Early Syphilis Cases by Stage at Diagnosis Minnesota, 2002-2012 Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Early Syphilis Cases Among MSM by Age Minnesota, 2012 (n=158) Mean Age = 38 years Range: 15 to 74 years MSM=Men who have sex with men Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Early Syphilis (ES) Cases Co-infected with HIV, 2006-2012 MSM=Men who have sex with men Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Characteristics of Early Syphilis Cases Among MSM, Minnesota, 2012 Gay and bisexual men account for 81% of cases among men. 65% of cases among MSM are White, but a disproportionate number of cases (23%) are African American. 51% in the City of Minneapolis and 27% live in the suburbs 59% of cases are also infected with HIV. Among cases interviewed by the MDH Partner Services Program: Commonly reported risk factors were meeting partners on the internet, anonymous sex, and no condom use. MSM=Men who have sex with men Early Syphilis includes primary, secondary, and early latent stages of syphilis.

What s Being Done in Minnesota? The MDH Partner Services Program continues to follow up on early syphilis cases and their sex partners. In 2004 the MDH implemented the Syphilis Elimination Effort (SEE). SEE activities include: Developed a clinician toolkit for syphilis testing and treatment; Created a new outbreak response plan; and Increased awareness among gay/bisexual men through advertising in magazines, bars, and websites. SEP website: www.health.state.mn.us/sep - includes several archived provider presentations and links to awareness campaign materials Physicians are encouraged to screen men who have sex with men at least annually and to ask about sex partners.

SURVEILLANCE SUMMARY

Summary of STD Trends in Minnesota From 2002-2012, the chlamydia rate increased by 86%. The rate of gonorrhea increased by 35% between 2011 and 2012. Rates of reported syphilis decreased in 2012 compared to 2011. Minnesota has seen a resurgence of syphilis over the past decade, with men who have sex with men and those co-infected with HIV being especially impacted. Persons of color continue to be disproportionately affected by STDs. STD rates are highest in the cities of Minneapolis and Saint Paul. However, chlamydia and gonorrhea cases in the Twin Cities suburbs and Greater Minnesota account for 60% of the reported cases in 2012. Adolescents and young adults (15-24 years) have the highest rates of chlamydia and gonorrhea, making up 68% of new infections in 2012. Between 2011 and 2012, the chlamydia rate increased by 7% and the gonorrhea rate increased by 35%. Primary/secondary syphilis cases decreased by 15%. Men who have sex with men comprised 81% of all male cases in 2012; cases among women remain low but are increasing.

Future Updates to STD Reporting New case report form to accommodate changes in gonorrhea treatment guidelines Case report form will be able to be filled out on a computer and printed to be mailed or faxed in Link will be put up on MDH website to indicate interest in future online provider portal for direct online reporting Letters will be sent in late May/early June to providers to introduce new case report form, provide link to sign up for future provider portal online reporting, and highlight new gonorrhea treatment guidelines