DFG-SPP Sphingolipids - Signals and Disease Meeting 2009 University Hospital Essen Hörsaal - Operatives Zentrum II
Friday, September 4, 2009 9.00 am Welcome Reception I) MEMBRANES, ENZYMES AND INHIBITORS 10.00 10.20 am Konrad Sandhoff, University of Bonn Does ceramide play a role in late endosomes? 10.20 10.50 am Felix Wieland, University of Heidelberg Specificity of protein lipid interaction within the hydrophobic core of membranes 10.50 11.10 am Stefan Schütze, University of Kiel Molecular mechanism of A-Smase activation in TNF receptosomes 11.10 11.40 am Annette Draeger, University of Bern Annexin 1 as a biomarker for ceramide platform dynamics 11.40 12.10 pm Pin Lan Li, Virginia Commonwealth University Lipid Rafts-Lyosome Signaling Platforms in Endothelial Cells 12.10 12.40 pm Emilio Clementi, Christiana Perrotta, DIBIT-H San Raffaele Institute Milano Acid sphingomyelinase, syntaxin 4 and nitric oxide: unsuspected links in CD95 signalling 12.40 13.10 pm Christoph Arenz, Humboldt University Berlin Small molecule inhibitors of acid Sphingomyelinase 13.15 14.15 pm Lunch
II) IMMUNE FUNCTIONS AND INFLAMMATORY DISEASES 14.20 14.50 pm Irina Petrarche, Indiana University The effect of sphingolipids dysregulation on lung parenchyma; Implications for human COPD 14.50 15.10 pm Erich Gulbins, University of Duisburg-Essen The role of sphingolipids in cystic fibrosis 15.10 15.30 pm Stefan Uhlig, Wolfgang Kübler, University Hospital of Aachen, Universitiy Hospital of Berlin The regulation of pulmonary vascular permeability by acid sphingomyelinase 15.30-15.50 pm Ralf Claus, University of Jena Hyperresponsiveness of mouse deficient in Asm reveals its vital role in early stages of inflammatory response 15.50 16.20 pm Coffee Braek 16.25 16.45 pm Klaus Fassbender, Silke Walter, University of the Saarland/Homburg an der Saar Acid Sphingomyelinase and Experimental Multiple Sclerosis 16.45 17.15 pm Ana Olivera, NIH Sphingosine-1-phosphate is a regulator of both the onset and the resolution of systemic anaphylaxis 17.15 17.35 pm Hermann Eibel, University of Freiburg Sphingosine 1-phospate receptors regulate migration of human B lymphocytes 17.35 17.55 pm Markus Gräler, Medical University of Hannover Distribution of sphingosine 1-phosphate from blood into lymphoid tissues: The role of sphingosine kinases 17.55 18.15 pm Burkhard Kleuser, University of Berlin Modulation of Langerhans cell migration via S1Psignalling 19.00 pm Dinner Restaurant Hülsmannshof
Saturday, September 5, 2009 III) DEVELOPMENT, DIFFERENTIATION AND DEATH 9.00 9.30 am Edward Schuchman, Mount Sinai School of Medicine Acid Ceramidase and Cell Survival: Specific applications to reproductive medicine and stem cell biology 9.30 10.00 am Paola Bruni, University of Florenz Sphingosine 1-phosphate signalling in skeletal muscle cell differentiation and regeneration 10.00 10.20 am Johannes Kornhuber, University of Nürnberg- Erlangen Acid sphingomyelinase and major depressive disorder 10.20 11.00 am Coffee Braek 11.00 11.30 am Tony Futerman, Weizman Institute of Science A critical role for synthesis of very long acyl chain ceramides in liver homeostasis 11.30 11.50 am Tobias Hartmann, University of the Saarland/ Homburg an der Saar Sphingolipid metabolism regulation by Alzheimer's disease amyloid beta peptides and precursor proteins 11.50 12.10 pm Florian Lang, University of Tübingen Ceramide in suicidal erythrocyte death 12.10 12.40 pm Richard Kolesnick, Memorial Sloan Kettering Cancer Center Vascular dysfunction and acute hypoxia impair double strand break repair in tumor stem cells 12.40 14.00 Lunch
IV) CARDIO-RENO-VASCULAR SYSTEM 14.00 14.20 pm Marcus van der Gieth, Charité University Hospital of Berlin The role of sphingolipids for endothelial functions 14.20 14.40 pm Bodo Levkau, University of Duisburg-Essen S1P in macrophage-driven inflammation and atherosclerosis 14.40 15.00 pm Bernhard Rauch, University of Düsseldorf The release of Sphingosine-1-phosphate from human platelets is dependent on thromboxane synthesis 15.00 15.20 pm Andrea Huwiler, Josef Pfeilschifter, University of Bern, University of Frankfurt The TGF- β-induced CTGF expression is under suppressive control of sphingosine kinase-1 in podocytes in vitro and in vivo End of SPP-Annual Conference 16.30 18.00 pm Meeting of all Applicants