Grants & Contracts Awards Processed by Grants & Contracts Join us as we congratulate the investigators listed below who have recently received a new or competitive renewal award (Based on information available in Grants Central as of 3/1/13): *Total award amount reflects Direct Costs only for the duration of the project February 2013 Principal Investigator: Jacqueline F. Bromberg, MD, PhD Department/Program: Medicine/Breast Cancer Project Title: Characterization and Functional Analysis of Breast Cancer-Derived Exosomes in Malignant Progression Total Award* Amount: $96,080 Award Date: 02/08/13 Project Duration: 5 Years Awarding Agency: Weill Medical College of Cornell University/National Institutes of Health Principal Investigator: Ross Levine, MD Department/Program: Medicine/Human Oncology & Pathogenesis Program (HOPP) Project Title: Role of TET2 Mutations in Malignant Transformation and Acute Myeloid Leukemia Total Award* Amount: $2,375,521 Award Date: 02/07/13 Project Duration: 5 Years Awarding Agency: National Cancer Institute Principal Investigator: Ana Ortega Molina, PhD Department/Program: Cancer Biology & Genetics Project Title: Epigenetics of Lymphoid Malignancies Total Award* Amount: $157,143 Award Date: 02/01/13 Awarding Agency: Leukemia and Lymphoma Society Principal Investigator: Chris Sander, PhD Department/Program: Epidemiology & Biostatistics/Biostatistics/Computational Biology Project Title: TARGET Analysis Portal Proposal Total Award* Amount: $186,502 Award Date: 02/01/13 Awarding Agency: SAIC-Frederick/National Cancer Institute 1 Memorial Sloan-Kettering Cancer Center
Principal Investigator: Lorenz Studer, MD Department/Program: Neurosurgery/Departmental/Developmental Biology Project Title: Oculomotor Resistance in ALS Total Award* Amount: $94,300 Award Date: 02/20/13 Awarding Agency: Project A.L.S. Principal Investigator: Larissa K.F. Temple, MD, FACS, FRCS(C) Department/Program: Surgery/Colorectal Project Title: Randomized Early Intervention Study to Improve Bowel Function in SPS Patients Total Award* Amount: $49,376 Award Date: 02/13/13 Awarding Agency: American Society of Colon and Rectal Surgeons Principal Investigator: Talia Zaider PhD Department/Program: Psychiatry Project Title: Theraputic Pathways to Improving End of Life Outcomes Among Families in Palliative Care Total Award* Amount: $24,250 Award Date: 02/11/13 Project Duration: 4 Years Awarding Agency: National Cancer Institute INTERNAL COMPETITION Principal Investigator: John Chodera, PhD Department/Program: Computational Biology Award Date: 02/01/13 January 2013 Principal Investigator: Cameron Brennan, MD Department/Program: Neurosurgery Project Title: Elucidating Mechanisms of Histone H3.3 Mutants-Mediated Oncogenesis in Pediatric Brain Cancers Total Award* Amount: $70,000 2 Memorial Sloan-Kettering Cancer Center
Principal Investigator: Yu Chen, MD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: Elucidating Mechanisms of Histone H3.3 Mutants-Mediated Oncogenesis in Pediatric Brain Cancers Total Award* Amount: $208,000 Principal Investigator: Ping Chi, MD Department/Program: Medicine Project Title: Elucidating Mechanisms of Histone H3.3 Mutants-Mediated Oncogenesis in Pediatric Brain Cancers Total Award* Amount: $70,000 Award Date: 01/14/13 Principal Investigator: Jarrod Dudakov, PhD Department/Program: Immunology Project Title: Role of Interleukin-22 (IL-22) in Thymic Function Total Award* Amount: $100,000 Award Date: 01/25/13 Awarding Agency: American Society of Hematology Principal Investigator: Ira J. Dunkel, MD Department/Program: Pediatrics Project Title: Children's Oncology Group: Per Case Reimbursement from NIH COG Chair Grant Total Award* Amount: $12,500 Awarding Agency: Children's Hospital of Philadelphia/National Cancer Institute Principal Investigator: Emily Foley, PhD Department/Program: Cell Biology 3 Memorial Sloan-Kettering Cancer Center
Principal Investigator: Alan M. Hanash, MD, PhD Department/Program: Medicine Project Title: IL-22, Innate Lymphoid Cells, and the Protection of Epithelial Tissues from GVHD Total Award* Amount: $150,000 Award Date: 01/25/13 Awarding Agency: American Society of Hematology Principal Investigator: Daniel Heller, PhD Department/Program: Molecular Pharmacology & Chemistry Principal Investigator: Ross Levine, MD Department/Program: Medicine/Human Oncology & Pathogenesis Program (HOPP) Project Title: Discovery of AID-dependent Epigenetic Mechanisms in Hematological Malignancies Total Award* Amount: $166,666 Principal Investigator: Ross Levine, MD Department/Program: Medicine/Human Oncology & Pathogenesis Program (HOPP) Project Title: Therapeutic Targeting of IDH1 and IDH2 Mutations in Acute Myeloid Leukemia (AML) and Chondrosarcoma Total Award* Amount: $249,778 Principal Investigator: Wendy G. Lichtenthal, PhD Department/Program: Psychiatry & Behavioral Sciences Project Title: Survivorship Project: ACS and MSKCC Collaboration to Adapt and Refine Meaning-Centered Group Psychotherapy for Breast Cancer Survivors Through Focus Groups and Intervention Evaluations Total Award* Amount: $384,424 Award Date: 01/23/13 Awarding Agency: American Cancer Society 4 Memorial Sloan-Kettering Cancer Center
Principal Investigator: Brian P. Marr, MD Department/Program: Surgery/Ophthalmic Oncology Project Title: Development of sd-rxrnas as Therapy for Retinoblastoma and Other Malignancies Total Award* Amount: $13,059 Award Date: 01/30/13 Awarding Agency: RXi Pharmaceuticals/ National Cancer Institute Principal Investigator: Joseph R. Osborne, MD, PhD Department/Program: Radiology/Molecular Imaging and Therapy Project Title: Immuno-PET With Anti-PSMA 89Zr-J591 mab For Molecular Imaging of Prostate Cancer Total Award* Amount: $108,750 Award Date: 01/28/13 Project Duration: 7 Months Awarding Agency: National Cancer Institute Principal Investigator: Cindy Puente, MA Department/Program: Cell Biology Project Title: Sensing and Relaying Autophagic Signaling by Ulk Kinase Complex Total Award* Amount: $126,696 Award Date: 01/25/13 Awarding Agency: National Institute of General Medical Sciences Principal Investigator: Raajit K. Rampal, MD, PhD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: The Role of WT1 in Epigenetic Alterations in Acute Myeloid Leukemia Total Award* Amount: $100,000 Award Date: 01/17/13 Awarding Agency: American Society of Hematology Principal Investigator: Gary Schwartz, MD Department/Program: Medicine/Melanoma and Sarcoma Project Title: Therapeutic Targeting of IDH1 and IDH2 Mutations in Acute Myeloid Leukemia (AML) and Chondrosarcoma Total Award* Amount: $249,778 Principal Investigator: Martin S. Tallman, MD Department/Program: Medicine/Leukemia 5 Memorial Sloan-Kettering Cancer Center
Project Title: ECOG and ACRIN Consolidation Total Award* Amount: $13,430 Award Date: 01/09/13 Awarding Agency: Eastern Cooperative Oncology Group/National Cancer Institute Principal Investigator: Richard White, MD, PhD Department/Program: Cancer Biology & Genetics INTERNAL COMPETITION Principal Investigator: Samuel Danishefsky, PhD Department/Program: Molecular Pharmacology & Chemistry Project Title: Testing the Immunogenicity of a New Unimolecular Vaccine Total Award* Amount: $50,000 Award Date: 01/23/13 Awarding Agency: Experimental Therapeutics Center 6 Memorial Sloan-Kettering Cancer Center