s Cath Lab EP LAB Intracardiac ICD First First DES stimulation First Non coronary Ablations surgical ASD

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Offsite Anesthesia for Cardiac Procedures From EP to the Cath Lab Dan Beck, M.D., M.S. Assistant Professor University of Colorado VA Eastern Colorado Health Care Objectives Understand history and future role procedures Overview of procedures Understand challenges in cardiac lab Identify our role in cardiac interventions Discuss anesthetic risks related to EP/Cath Case Discussions and Complications What do they do up there? History Cath Lab Diagnostic Cath STEMI PCI Peripheral angio stents IABP Percutaneous Assist Device PFO/ASD closure Perc Valve TAVI, Mitraclip LAA occlusion EP LAB EP studies mapping Atrial and Ventricular ablation Pacemakers, ICD, BiV Generator Change Cardioversion Lead Extraction 1967 Intracardiac stimulation and mapping 1970s Surgical approaches to arrhythmia control 1976 First Nonsurgical ASD closure 1980 ICD 1986 1991 First RF coronary Ablations stent 2002 First Nonsurgical AVR 2003 First DES Future Trends Technological advances Over 5 million people have heart failure Expected to grow 5 fold in 20 years Increasing numbers using implanted devices CRT devices reduce hospitalization 50% Medical Care extending lifespan 25% increase in EP procedures last 10 yrs You will treat these patients somewhere

New Technology Welcome to the Cath Lab Advanced Technology More Complex Procedures Often longer procedures New procedures = unknown complications Too Sick for Surgery? Lower Risk in Cath lab??? High risk for sedation!!! Unique Environment Physical Limitations Cultural and political obstacles OR pressures and Cath lab pressures Communication between staff Fluoro Mobile and unique imaging ICE, IVUS, FFR Physical Environment Set up for convenience of the proceduralist Limited Space Moving Equipment Poor access to Patient Remote Location Transport to OR can be time consuming Help can be very far away Typical resources not available Room Layout Practice models 2010s Anesthesia Monitors and cart Anesthesia Machine L e a d W a l l Window to control room Monitoring screen C arm Patient Procedural table Defibrillator Ablation Unit D O O R ~2/3 of centers use a mix of anesthesia providers (team MD or CRNA model) and RN sedation 1/3 exclusively anesthesia or RN sedation ¼ responded anesthesia was warranted >50% of time regardless of availability Frequent reasons for RN sedation alone Unavailability of anesthesia services Difficulty in scheduling Prolonged OR turnover times

Cultural differences vs the OR Cardiologist is a medical director Used to working with RN, techs who take orders Not used to working with another MD May not know full skill set of anesthesiologist May think sedation is our only role in their procedure Roles and responsibilities of care unclear Hemodynamics, oxygenation, patient position Lack of communication leads to conflict and poor overall patient care Cultural Obstacles Rationale for requesting anesthesia presence High risk patient High risk procedure May assume our presence allows them to do everything exactly as they normally would Location OR vs lab vs hybrid OR Appropriate Anesthetic sedation vs controlled airway Drug of choice ( Just give some propofol ) Not experts in high risk patient anesthesia You are, that s why they consulted you! Recognize the Home Team s Skill Cardiovascular knowledge Internal medicine background Procedural ability Vascular access, echo, temp pacing wires, IABP Lab ancillary staff ABGs, mixing gtts, getting supplies Navigating the foreign environment Calling for help OR pressure vs Cath/EP lab needs Surgeons have block time, elective needs are fixed on a week to week basis Offsite locations create staffing challenges Running 1 room all day remote offsite 1 4 rooms in OR Varies based on hospital layout Cath/EP lab are high volume, fast turnover More daytime unscheduled cases Unpredictable needs for anesthesia Who are these patients? CAD and arrhythmia Dementia PTSD CVA Obesity; OSA; difficult airway Obstructive and restrictive lung disease Low EF with accompanying sequelae Renal Insufficiency Hepatic Insufficiency Diabetes and other metabolic syndromes What the patients and proceduralists bring to the table? Histories and comorbidities Uncommon medications Unique to EP patients Interventionalists are surgeons of medicine Narrow focus, may not be aware of all history Urgent or emergent procedures may prevent thorough H&P

Unique Procedures Electrophysiology studies Electrophysiology Studies Mapping studies using stimulation and response Multiple catheters in heart Induced and spontaneous arrhythmias Isolate arrhythmia circuit Endocardial venous access Epicardial pericardial sheath Pre procedural workups H&P, TTE, Right/left heart cath Anti coagulation status Monitors Standard ASA monitors Defibrillator pads Radiolucent 12 lead ECG Supine position on fluoro table with C arm Intra procedural anesthetic needs MAC vs GETA Intra procedural approach Pre procedural TTE or TEE Access via groin Venous only for right sided procedures Trans septal puncture for Left sided procedures Anticoagulation, ACT, protamine reversal Intraprocedural imaging Fluro, ICE, TEE guided Mapping may take hours Isolating arrhythmia focus or pathways EP mapping studies Catheter placement High right atrium RV apex Adjacent to His bundle tricuspid annulus Coronary sinus catheters Allows pacing recording ability to map and detect abnormal conduction pathways Catecholamine infusions to help incite arrhythmia Confirms diagnosis prior to intervention Anesthetic Drugs Commonly assumed anesthetic drugs influence cardiac conduction and myocardial refractoriness Inhalational, IV agents, NMB, opioids, and anticholingerics may all have effects Volatile anesthetics Isoflurane/Sevoflurane AV nodal conduction unchanged, His purkinje slowed Rocuronium most free of CV side effects Opioids can have vagolytic effects Propofol may alter HR in either direction All agents may lower SVR and cause reflex tachycardia RF Ablation Localized burn similar to electrocautery Power and length of burn determines depth Catheter size, irrigated and cooled catheters Irrigated catheters add volume to circulation Risks: steam pops, clotting, deep burns Monitor patient for 20 30 minutes during waiting period Post RF study try to stimulate arrhythmia or test timing of pathway

ICD or PPM Vascular access Usually Left subclavian Pocket formation under LA Wire placement Can be lengthy searching for ideal place Wire burrowed/screwed into myocardium ICD Device Testing Cardioversion R on T induced VF Device defibrillates.. hopefully EP Challenges Prolonged procedure 4+ hours of MAC with little stimulation Initial studies may request no sedation PPM or ICD placement may request no NMB Detect phrenic nerve stimulation from pacing Common Complications Vascular access issues Unstable arrhythmias Complete heart block requiring PPM Cardiac perforation and tamponade Left side procedures Pulmonary vein stenosis Atrio esophageal fistulas stroke Lead Extractions ICD or PPM lead removal Endocarditis Lead failure/multiple lead replacements Traction removal vs laser or mechanical extraction Adhesions to great veins Intramyocardial adhesions Myocardial injury perforation Lead Extraction Preparedness Pre procedural IV access Arterial line Blood bank Systems based planning Surgical backup Perfusionist backup OR availability Procedure and Disposition GETA TEE guidance Anesthesia or cardiology Lead position pre extraction Presence of effusions ICU Monitoring Post op TTE if concerns Pericardial effusions

Clear Communication is Key Discuss with the proceduralist What exactly is he going to be doing? Length of procedure Points of potential instability Plan for those events Patient specific risk factors Do we need/have surgical backup? Ongoing communication Listen via headset and communicate often Airway Emergencies ~40% of cases require airway adjuncts or interventions Physical access to airway limited Trentman, TL. JCVA 2009. Case Discussion 68 yo M with SVT resulting in syncope, fall with facial fractures repaired in OR, jaw wired shut presents for EP mapping and ablation MAC with remifentanil and propofol IV kink results in drug delivery backup Kink discovered and adjusted patient received bolus of both agents Apnea ensued Case continued Anesthesia team (CRNA/MD) unable to mask ventilate Wire cutters not immediately available Call for help Emergency cricothyrotomy to establish definitive airway Too Sick for Surgery? New or unfamiliar procedures Need for unusual approaches and equipment Unanticipated course of procedure Excellent communication is obligatory Anesthetic Plan Proceduralist doesn t dictate your anesthetic Understand physiologic needs of the procedure Assess your patient s medical needs and ability to tolerate the procedures Tailor your plan to your environment Access to airway mid procedure Availability of surgical and OR backup Communicate, communicate, communicate

Equipment If you even think about needing it, bring it Consider airway adjuvants Multiple blades, video laryngoscope, FOB Special drugs, gtts, pumps, tubing Ultrasounds, TEE, central lines Plan for space limitations Understand what equipment your offsite location has it is a cardiology suite Anesthesia Personnel safety Moving equipment Pay attention, keep your eyes open Radiation safety Lead aprons, lead shield, eye protection Radiation dosimeter Radiation scatter and inverse square law Time, barriers, and distance Summary Understand the procedures, risks, pitfalls Communication and planning are key Clearly delineate patient care roles Understand your environment and plan for it Use your anesthetic knowledge to create the proper plan for your patient Be ready for everything