Reducing Opioid Deaths: Arizona s Emergency Declaration & Response

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Reducing Opioid Deaths: Arizona s Emergency Declaration & Response September 15, 2017 Sheila Sjolander, Assistant Director Arizona Department of Health Services

Emergency Declaration On June 5, 2017, Arizona Governor Doug Ducey declared a State of Emergency due to an opioid overdose epidemic

What are we doing about it?

Emergency Declaration ADHS Responsibilities Provide consultation to governor on identifying and recommending elements for Enhanced Surveillance Initiate emergency rule-making for opioid prescribing and treatment practices Develop guidelines to educate providers on responsible prescribing practices Provide training to local law enforcement agencies on proper protocols for administering naloxone in overdose situations Provide a report on findings and recommendations by September 5, 2017

What progress has been made since June 5 th?

ADHS Response Activities Health Emergency Operations Center Activated 70 staff 7,000 hours since June 5 th addressing opioidrelated response activities

Emergency Declaration Enhanced Surveillance Authorized by A.R.S. 36-782 Benefits of enhanced surveillance: More timely data Ability to more accurately assess the burden Provides information to build recommendations to better target prevention and intervention

Enhanced Surveillance Enhanced Surveillance Includes New Reporting, Information Sharing and Laboratory-testing Suspected opioid overdoses Suspected opioid-related deaths Neonatal Abstinence Syndrome Naloxone administered Naloxone dispensed

Emergency Declaration Enhanced Surveillance June 15 Sept. 7 Weekly updates posted at www.azhealth.gov/opioid

1,726 doses of naloxone administered pre-hospital through Sept. 7

Emergency Declaration ADHS Responsibilities Provide consultation to governor on identifying and recommending elements for Enhanced Surveillance Initiate emergency rule-making for opioid prescribing and treatment practices Develop guidelines to educate providers on responsible prescribing practices Provide training to local law enforcement agencies on proper protocols for administering naloxone in overdose situations Provide report on findings and recommendations by September 5, 2017

ADHS Response Activities Opioid Prescribing &Treatment Rules ADHS initiated immediately ADHS submitted draft rules to Attorney General Attorney General approved and submitted final rules to Secretary of State - July 28 Emergency rules in effect - July 28 Initiating regular rulemaking

ADHS Response Activities Opioid Prescribing &Treatment Rules R9-10-120, Article 1. General Focus on health and safety Provide regulatory consistency for all licensed health care institutions Rulemakings In Progress - Opioid Prescribing and Treatment (Emergency) http://azdhs.gov/director/administrative-counsel-rules/rules/index.php#rulemakings-active-opioidprescribing Notice of Emergency Rulemaking http://azdhs.gov/documents/director/administrative-counsel-rules/rules/rulemaking/opioidprescribing/approved-emergency-rulemaking.pdf

ADHS Response Activities Opioid Prescribing &Treatment Rules Establish, document, and implement policies and procedures for prescribing, ordering, or administering opioids as part of treatment Include specific processes related to opioids in a health care institution s quality management program; and Notify the Department of a death of a patient from an opioid overdose.

ADHS Response Activities Opioid Prescribing &Treatment Rules Includes: Conducting a physical exam Checking the Controlled Substances Prescription Monitoring Program (CSPMP) Conducting a substance abuse risk assessment Obtaining informed consent

Emergency Declaration ADHS Responsibilities treatment practices Develop guidelines to educate providers on responsible prescribing practices Provide training to local law enforcement agencies on proper protocols for administering overdose situations Provide report on findings

ADHS Response Activities Prescribing Guidelines Update Since the June 5 th declaration, the Rx Initiative Healthcare Advisory Team has convened six times to discuss revisions Draft update released Sept. 5 Aim to reduce overreliance on opioid therapy and make safety a priority in managing acute and chronic pain Finalize by end of December Last Revision: September 1, 2017

Emergency Declaration ADHS Responsibilities Provide consultation to governor on identifying and Provide training to local law enforcement agencies on proper protocols for administering naloxone in overdose situations Provide report on findings and recommendations by September 5, 2017

ADHS Response Activities Naloxone Trainings Training Date & Location June 19 - Flagstaff 81 # Trained June 23 - Tucson 245 June 29 - Phoenix 445 July 17 - Yuma 212 983

ADHS Response Activities Naloxone Distribution To date, ADHS has distributed 4,852 kits of naloxone to 50 law enforcement agencies.

ADHS Response Activities Naloxone Standing Orders

ADHS Response Activities Naloxone Public Information

What have we learned from the enhanced surveillance?

Enhanced Surveillance Period: June S M T W T F S 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 July S M T W T F S 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 August S M T W T F S 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Opioid Overdoses & Deaths

The majority of possible opioid overdoses reported during the enhanced surveillance period were male. 41% 59%

More males than females had a possible opioid overdose. The most overdoses were reported in males in the 25 34 year old age group. 350 300 250 Female 200 150 100 50 0 0-14 Y 15-24 Y 25-34 Y 35-44 Y 45-54 Y 55-64 Y 65-74 Y 75 350 300 250 Male 200 150 100 50 0 0-14 Y 15-24 Y 25-34 Y 35-44 Y 45-54 Y 55-64 Y 65-74 Y 75

87% of possible opioid overdoses reported during the enhanced surveillance period had at least one pre-existing condition.

Chronic pain was the most common pre-existing condition that was reported by individuals reported with a possible opioid overdose. Chronic pain Other Behavioral Health Conditions Depression Anxiety Mental health & pain Bipolar Disorder Cancer Mental health & cancer 0 20 40 60 80 100 120 140 160 180 200

In 2017, 672 (83%) of individuals who had an opioid overdose during the enhanced surveillance period had more than one opioid prescription. 250 200 150 100 50 0 1 Rx 2-5 Rx 6-8 Rx 9-19 Rx 20 Rx

For individuals with both fatal and non-fatal possible opioid overdoses reported, the most common drug combination was opioids and benzodiazepines. 4% 10% 4% 17% 43% 40% 43% 39% Non-fatal Fatal Opioid Only Opioid + Benzodiazepine Opioid + Muscle Relaxer Opioid + Zolpidem

41% of individuals who experienced an overdose during the enhanced surveillance period had 10 or more providers prescribe opioids over the last year. 400 350 300 250 200 One opioid prescription 150 100 More than one opioid prescription 50 0 1 2-5 6-9 10

Heroin and oxycodone were the drugs most commonly noted in overdose reports. Of those with heroin noted in the overdose report, 17% were fatal. Heroin Oxycodone Heroin Oxycodone Benzodiazepine Hydrocodone Hydrocodone Benzodiazepine Tramadol 0% 5% 10% 15% 20% Tramadol

The majority of mothers of NAS infants presented with either meth or heroin. Meth Heroin Marijuana Cocaine Oxycodone Morphine Synthetic cannabinoid Benzodiazepine Tramadol 0 5 10 15 20 25 30

Other Activities

Other Activities 50 State Review on Opioid Related Policy Treatment Capacity Survey Public health chronic pain initiative: www.azhealth.gov/chronicpainmanagement Drug Overdose Mortality Review Team For more information see azhealth.gov/opioid

Emergency Declaration ADHS Responsibilities Provide consultation to governor on identifying and recommending elements for Enhanced Surveillance Provide report on findings and recommendations, including additional needs and response activities, and preliminary recommendations that require legislative action to the Governor by September 5, 2017

Opioid Action Plan: Opioid Overdose Epidemic Response Report

Next Steps: Implementation

azhealth.gov/opioid for more information