Formulary Item Restrictions and/or Advice Site availability C&W CNWL Typical Antipsychotic drugs Chlorpromazine 25mg Chlorpromazine 50mg Chlorpromazine 100mg Chlorpromazine 25mg/5ml syrup Chlorpromazine 100mg/5ml syrup Chlorpromazine: If IM administration is necessary, haloperidol is preferred. Chlorpromazine is irritant and may cause hypotension and tachycardia BP should be monitored for 30 mins after IM. Not licensed for IV use; should not be used IV IM doses are lower than equivalent There is no convincing evidence that Approximate equivalent doses of Advice of Royal College of Chlorpromazine 25mg/ml Flupentixol 3mg Haloperidol 500mcg capsule Haloperidol 1.5mg Haloperidol 5mg Haloperidol 10mg Haloperidol 2mg/ml liquid Haloperidol 5mg/ml IM doses are lower than equivalent There is no convincing evidence that Approximate equivalent doses of Advice of Royal College of
Levomepromazine 25mg Levomepromazine 25mg/ml IM doses are lower than equivalent There is no convincing evidence that Approximate equivalent doses of Advice of Royal College of Pimozide 4mg Prochlorperazine 5mg Prochlorperazine 5mg/5ml syrup Prochlorperazine 25mg suppository Prochlorperazine 12.5mg/ml Promazine 25mg Promazine 25mg/5ml oral solution Sulpiride 200mg Sulpiride 400mg Sulpiride 200mg/5ml SF oral suspension Trifluoperazine 1mg Trifluoperazine 5mg Trifluoperazine 5mg/5ml oral liquid Trifluoperazine 10mg SR capsule Trifluoperazine 15mg SR capsule IM doses are lower than equivalent There is no convincing evidence that Approximate equivalent doses of Advice of Royal College of
Zuclopenthixol dihydrochloride 10mg Zuclopenthixol dihydrochloride 25mg Zuclopenthixol acetate 50mg/ml Zuclopenthixol acetate 100mg/2ml (Clopixol Acuphase ) Atypical Antipsychotics Amisulpride 50mg Amisulpride 200mg Amisulpride 400mg Amisulpride 100mg/ml solution Atypical antipsychotics: Extrapyramidal symptoms and No evidence supporting use in No evidence supporting prn use of There is no convincing evidence that Approximate equivalent doses of Advice of Royal College of
Aripiprazole 5mg Aripiprazole 10mg Aripiprazole 10mg orodispersible Aripiprazole 15mg Aripiprazole 15mg orodispersible Aripiprazole 7.5mg/ml (1.3-ml (9.75- mg) vial) Clozapine 25mg Clozapine 100mg (Zaponex ) Atypical antipsychotics: Extrapyramidal symptoms and No evidence supporting use in No evidence supporting prn use of IM doses are lower than equivalent There is no convincing evidence that Approximate equivalent doses of Advice of Royal College of Atypical antipsychotics: Extrapyramidal symptoms and No evidence supporting use in No evidence supporting prn use of Registration with the Zaponex Treatment Access System (Ztas) and routine blood counts are required due to the risk of agranulocytosis
Olanzapine 2.5mg Olanzapine 5mg Olanzapine 7.5mg Olanzapine 10mg Olanzapine 15mg Olanzapine 20mg Olanzapine 5mg orodispersible Olanzapine 10mg orodispersible Olanzapine 15mg orodispersible Olanzapine 20mg orodispersible Olanzapine 10mg Quetiapine 25mg Quetiapine 100mg Quetiapine 150mg Quetiapine 200mg Quetiapine 300mg Quetiapine 50mg M/R Quetiapine 200mg M/R Quetiapine 300mg M/R Quetiapine 400mg M/R Atypical antipsychotics: Extrapyramidal symptoms and No evidence supporting use in No evidence supporting prn use of IM doses are lower than equivalent There is no convincing evidence that Approximate equivalent doses of Advice of Royal College of Atypical antipsychotics: Extrapyramidal symptoms and No evidence supporting use in No evidence supporting prn use of There is no convincing evidence that Approximate equivalent doses of Advice of Royal College of
Risperidone 500mcg Risperidone 1mg Risperidone 2mg Risperidone 3mg Risperidone 4mg Risperidone 6mg Risperidone 3mg orodispersible Risperidone 4mg orodispersible Risperidone 1mg/ml liquid Risperidone 1mg orodispersible Risperidone 2mg orodispersible Atypical antipsychotics: Extrapyramidal symptoms and No evidence supporting use in No evidence supporting prn use of There is no convincing evidence that Approximate equivalent doses of Advice of Royal College of chlorpromazine/day) see BNF Antipsychotic depot s - typicals 20mg/ml 100mg/ml 200mg/ml 40mg/2ml 50mg/0.5ml 100mg/ml 25mg/ml 12.5mg/0.5ml 50mg/0.5ml Haloperidol decanoate 50mg/ml Haloperidol decanoate 100mg/ml Pipotiazine palmitate 50mg/ml Pipotiazine palmitate 100mg/2ml
Zuclopenthixol decanoate 200mg/ml Zuclopenthixol decanoate 500mg/ml Antipsychotic depot s - atypicals Risperidone 25mg depot Risperidone 37.5mg depot Risperidone 50mg Antimanic drugs Valproic acid 250mg EC Lithium carbonate 200mg SR Lithium carbonate 250mg Lithium carbonate 400mg MR Lithium citrate (Li-Liquid) 509mg/5ml Lithium citrate (Priadel) 520mg/5ml Mental Health Trust Only Preparations vary widely in bioavailability; changing the preparation requires the same precautions as initiation of treatment Note: Lithium carbonate 200mg lithium citrate 509mg