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4th Annual Multidisciplinary Colorectal Oncology Course Current Care Updates Cleveland, Ohio 44106

About the Course This regional symposium will focus on providing an in-depth and up-to-date review of the multidisciplinary management of colorectal cancers. Oncologists, radiation oncologists, surgeons, and nurses with an interest in the management of patients with colorectal cancer should attend this course. Learning Objectives As a result of attending the course, the participant will be able to: Discuss liver-directed approaches to colorectal cancer metastases. Identify indications for pre-operative treatment of rectal cancer. Implement approaches toward recurrent rectal cancer. Program Location Cleveland, Ohio Phone: 877.707.8999 Faculty Disclosure The Cleveland Clinic Foundation Center for Continuing Education has implemented a policy to comply with the current Accreditation Council for Continuing Medical Education Standards for Commercial Support requiring resolution of all faculty conflicts of interest. Faculty declaring a relevant commercial interest will be identified in the activity syllabus. Information For further information about this activity, contact Sheryl Krall at Local: 216.444.7924 Toll Free: 800.223.2273 x47924 Email: kralls2@ccf.org

Accreditation The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Cleveland Clinic Foundation Center for Continuing Education designates this live activity for a maximum of 5.50 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association Council for Category 2 credit. The Ohio Board of Nursing will accept at face value the number of contact hours awarded for an educational activity that has been approved for CE by a nationally accredited system of CE approval. Nurses are able to obtain CE that has been approved or provided by a nationally recognized accreditation system of continuing education. Examples include: The American Nurses Credentialing Center (ANCC) The Accreditation Council for Continuing Medical Education (ACCME) The International Association for Continuing Education and Training (IACET) Deadline for Registration & Cancellation Register at. The deadline for registration is 5:00 pm (PST), Wednesday, October 11, 2017. A request for refund must be received in writing by October 6, 2017. A $50 cancellation fee will be deducted from the refund for all cancellations after October 6, 2017. No refunds will be given after October 16, 2017. For questions about registrations, please call 216.448.8710 or email cmeregistration@ccf.org. Course Co-Directors Matthew Kalady, MD Cleveland Clinic Cleveland Clinic Faculty Sudha Amarnath, MD Department of Radiation Oncology James Church, MD Conor Delaney, MD, PhD Digestive Disease and Surgery Institute Bassam Estfan, MD Emre Gorgun, MD Hermann Kessler, MD, PhD Brandie Leach, LGC Genomic Medicine Institute Michael McNamara, MD Alok Khorana, MD Cleveland Clinic Robert Pelley, MD Cristiano Quintini, MD Department of Hepato-pancreato-biliary & Transplant Surgery Laurel Ralston, DO Taussig Cancer Institute Marc Shapiro, MD Scott Steele, MD Michael Valente, DO Joseph Veniero, MD, PhD Department of Diagnostic Radiology

Agenda, Cleveland, Ohio 7:00-8:00 am Registration/Continental Breakfast 7:00-7:45 am Comprehensive Colorectal Cancer Program Update (Non-CME) (For CC/CCHS Employees only) 8:00 am Welcome/Introduction Matthew Kalady, MD/Alok Khorana, MD EMERGING TOPICS Moderator: Alok Khorana, MD 8:05 am Emerging Data in Resected Colon Cancer: Integrating IDEA into Practice Alok Khorana, MD 8:30 am Alarming Trends and Implications of Colorectal Cancer in Young Patients James Church, MD 8:55 am Managing Psychosocial Aspects of Colorectal Cancer Laurel Ralston, DO 9:20 am What s New in Hereditary Colorectal Cancer Syndromes? Brandie Leach, LGC 9:45 am Break RECTAL CANCER Moderator: Matthew Kalady, MD 10:15 am The National Accreditation Program for Rectal Cancer: Multidisciplinary Standards Matthew Kalady, MD 10:35 am Short or Long? Approaches to Neoadjuvant Radiation Therapy Sudha Amarnath, MD 10:55 am New Technical Approaches to Rectal Cancer Surgery: TaTME Conor Delaney, MD, PhD 11:15 am Team Approach to Recurrent Rectal Cancer Scott Steele, MD 11:35 am Case Presentations and Panel Discussion Drs. Amarnath, Delaney, Steele, Pelley, and Veniero 12:15 pm LUNCH METASTATIC COLORECTAL CANCER Moderator: Bassam Estfan, MD 1:15 pm Should the Primary Tumor Be Resected? Emre Gorgun, MD 1:35 pm Liver-directed Surgical and Ablative Therapy Cristiano Quintini, MD 1:55 pm Novel Therapies for Metastatic Colorectal Cancer Michael McNamara, MD 2:15 pm Case Presentations/Panel Discussion Drs. Gorgun, Quintini, McNamara, Kessler, Valente, and Shapiro 3:00 pm Adjourn Time for questions and answers will be included in each presentation.

Registration Fees Course #02010761 4th Annual Multidisciplinary Colorectal Oncology Course Current Care Updates Cleveland, Ohio Registration Fees: Physician: $195 Non-Physician: $50 Resident/Fellow: $50* Corporate $75 *Letter from program chairman or department chairman must accompany Resident/Fellow registration. Fee includes registration materials, continental breakfast, breaks, and lunch. To register online go to: CCF employees should register online at the above web address. Americans with Disabilities Act The Cleveland Clinic Foundation Center for Continuing Education fully intends to comply with the legal requirements of the Americans with Disabilities Act. If you need assistance, please notify Cleveland Clinic at 216.444.7924 at least two weeks prior to the activity.

4th Annual Multidisciplinary Colorectal Oncology Course Current Care Updates Cleveland, Ohio The Cleveland Clinic Foundation Cleveland Clinic Taussig Cancer Institute 9500 Euclid Ave. CA50 Cleveland, OH 44195