Optimizing ART Outcome through Individualized Protocols

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Optimizing ART Outcome through Individualized Protocols @ forthcoming International Congress on 4th and 5th February 2012 at Hotel Atria, Bengaluru Hosted by KISAR (Karnataka Chapter of ISAR) & ISMAAR (The International Society for Mild Approaches in Assisted Reproduction)

Dear Friends A scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents eventually die and a new generation grows up that is familiar with it. Max Planck ART is associated with health risks to the mother and child. Today, ovulation induction protocols involve several controversies in the drugs used, types of protocol and the risks involved with it. This update on ovarian stimulation will discuss many current strategies for ovarian stimulation, individual variability in ovarian response and its possible implications on oocyte and embryo quality and endometrial receptivity. Being aware of the complex interplay between the ovarian physiology, ovarian stimulation, in vitro embryo development and IVF outcome will help in optimizing the ART outcome. This conference aims to present knowledge that can be translated into daily practice by identifying patients who require conventional or mild stimulation for an optimal outcome. Furthermore, the conference will address the protocols and laboratory systems needed to offer low-cost IVF in developing countries. Jean Piaget has rightly said Scientific knowledge is in perpetual evolution; it finds itself changed from one day to the next. We await your participation. Warm Regards Madhuri Patil C. Sharath Kumar Bina Vasan Devika Gunasheela Geeta Nargund President Secretary Treasurer Joint Secretary President KISAR (Karnataka Chapter of ISAR) ISMAAR Course Objectives At the conclusion of this conference the participants should be able to: know the effects and risks of Ovulation Induction critically evaluate the prediction and prevention of OHSS understand complexity of different ovulation induction protocols in terms of drug and dose used and desired endpoint know that individual differences exist in response to ovarian stimulation which are related to intrinsic ovarian differences and its implications critically evaluate the value of new methods Mild and Natural cycle IVF understand the implications of single embryo transfer evaluate the value of IVM identify the best methods to test ovarian reserve and monitor ovulation Induction cycles understand the implications of low-cost IVF for developing countries Who should attend? Infertility and ART specialist Obstetrician and Gynecologist Clinical embryologist Postgraduate students

Day 1 Saturday 4th February 2012 Session 1 9.00 10.00 AM Effects of conventional COS on the outcome of ART Think before you discard the old 9.00 9.15 AM Impact of COS on oocytes and embryos Satish Adiga 9.15 9.30 AM Implications of ovarian stimulation on endometrial receptivity - Bina Vasan 9.30 9.45 AM Discussion Session 2-09.45 10.45 AM Ovulation Induction strategies Exciting options for the future 09.45 10.00 AM Individualizing ovarian stimulation in ART Korula George 10.00 10.15 AM Use of oral anti-oestrogens in ART cycles Prof. Svend Lindenberg 10.15 10.30 AM OHSS free clinic - Is it a dream? Reeta Biliangady 10.30 10.45 AM Discussion 10.45 11.15 AM Coffee Break 11.15 11.45 AM Keynote Address Chairpersons: Kamini Rao, Madhuri Patil Mild ART should it become the norm? Prof. Geeta Nargund 11.45 12.15 PM Inauguration 12.15 1.15 PM Panel Discussion Stump the experts Point counterpoint Moderator Madhuri Patil Panel Members Svend Lindenberg, Mette Munk, Anuja Kamat, Deepika K, Fessy Louis, Mala Arora, Shobhana Patted 1.15 2.15 PM Lunch Session 3 2.15 3.30 PM All about Mild ART Changing Attitudes Changing practices 2.15 2.45 PM Indications and role of natural cycle and modified natural cycle IVF today Prof. Geeta Nargund 2.45 3.00 PM From aggressive to mild stimulation Is it better? Kannaki C V 3.00 3.15 PM Luteal Phase supplementation on Mild/natural cycle ART Bharati Dorepatil 3.15 3.30 PM Discussion Session 4-3.30 4.00 PM Paper Presentation - Best 3 posters Session 5-4.00 5.15 PM 4.00 5.00 PM Debates Chairpersons: Prof. Willem Ombelet, Prof. Svend Lindenberg 4.00 4. 30 PM Debate 1 GnRH agonist or Antagonist which is better in Mild ART? GnRH agonist B. Ramesh GnRH Antagonist Nirmala R 4.30 5.00 PM Debate 2 Will mild stimulation replace conventional COS in ART practice? For Sunita Tandulwadkar Against Nandita Palshetkar 5.00 5.15 PM Discussion 5.15 5.45 PM Keynote Address Chairpersons: Geeta Nargund, Dhiraj Gada Legal Issues in Infertility Practice Kamini Rao 5.45 6.00 PM Discussion

Day 2 Sunday 5th February 2012 Meet the Experts Breakfast Session 8.00-9.00 AM Topics 1. Explore the protocols - Experts: Prof. Geeta Nargund, Prof. Willem Ombelet, Kamini Rao 2. IVM When and how - Experts: Prof. Svend Lindenberg, Shreyas Padgaonkar, Devika Gunasheela 3. Lab aspects of ART - Prof. Mette Munk, Vyjayanthi, Satish Adiga Session 6 9.00 10. 15 AM Mild Stimulation Varied options in varied situations 9.00-9.15 AM Minimal stimulation protocols in IUI Prof. Willem Ombelet 9.15 9.30 AM Natural cycle/mild stimulation in women with poor ovarian reserve/oocyte donors Abha Majumdar 9.30 9.45 AM Minimal stimulation in women with PCOS Sonia Mallik 9.45 10.00 AM Role of mild stimulation in fertility preservation in young cancer patients Mandakini Parihar 10.00 10.15 AM Discussion 10.15 10.45 AM Coffee Break Session 7 10.45 12.00 PM Uncertainties with IVM Would they resolve soon? 10.45 11.15 AM Keynote Address Does IVM with mild stimulation improve outcome in PCOS? Prof. Svend Lindenberg 11.15 11.30 AM IVM in natural and FSH primed cycles Devika Gunasheela 11.30 11.45 AM IVM & fertility preservation in Cancer patients Prof. Mette Munk 11.45 12.00 PM Discussion Session 8 12.00 1.15 PM Embryos - Are they different? 12.00 12.15 PM Ovarian stimulation and embryo quality - Less is more Prof. Mette Munk 12.15 12.30 PM Non invasive assessment of embryo - Does it improve embryo selection and is it cost effective in Indian Scenario? - Vyjayanthi 12.30 12.45 PM With Mild ART are we moving towards SET Shreyas Padgaonkar 12.45 1.00 PM Are Mild ART derived blastocysts more favorable than conventional COS derived ones? Srinivas MS 1.00 1.15 PM Discussion 1.15 2.00 PM Lunch Session 9 2.00 3.15 PM Safety and affordability Do no harm to the patient and to her pocket 2.00 2.15 PM Affordability and access to ART in India Manish Banker 2.15 2.30 PM Soft protocols for Indian population Dhiraj Gada 2.30-2.45 PM Natural cycle IVF - Is it effective and cost effective? Nalini Mahajan 2.45 3.00 PM Discussion 3.00 3.30 PM Keynote Address Low cost IVF in developing countries What does it Imply? Prof. Willem Ombelet 3.30 4.30 PM Panel Discussion Ground Realities Can our patients benefit? Impact of Milder stimulation upon indicators of benefit in Indian scenario Efficacy, safety, time, cost and quality Moderator Mirudhubashini Govindarajan Panel Members Prof. Willem Ombelet, Abha Majumdar, Asha Gangane, B.R Desai, Jyoti Menon, Kallappa Mavintop, Nivedita Shetty Session 10 4.30 5.45 PM Select Investigations in select situations - Can it reduce the burden? 4.30 4.45 PM Stem Cells and Ovarian Reserve - Deepa Bhartiya 4.45 5.00 PM Assessment of ovarian reserve and its implications on selecting an ideal protocol for COS Padmarekha Jirge 5.00 5.15 PM Can use of advanced ultrasound technology make a difference in investigating and treating? Prof. Geeta Nargund 5.15 5.30 PM Role of office hysteroscopy in Mild ART programs C. Sharath Kumar 5.30 5.45 PM Discussion 5.45 PM Valedictory Session

ISMAAR BOARD Geeta Nargund Rene Frydman Bart Fauser Stuart Campbell Osama Kato Svend Lindenberg RC Chian Willem Ombelet Pasquale Patrizio Faculty International Prof. Geeta Nargund Prof. Mette Munk Prof. Svend Lindenberg Prof. Willem Ombelet National Abha Majumdar Anuja Kamat Asha Gangane B. Ramesh B.R Desai Bharti Dorepatil Bina Vasan Deepa Bhartiya Deepika K Devika Gunasheela Dhiraj Gada Fessy Louis Jyoti Menon Kallappa Mavintop Kannaki C V Kamini Rao Korula George Madhuri Patil CONGRESS EXPENSES: KISAR BOARD Madhuri Patil C. Sharath Kumar Bina Vasan Devika Gunasheela B. R. Desai Srinivas MS Asha Gangane Satish Adiga Reeta Biliangady EARLY REGISTRATION (before 15 January, 2012) Consultants Both Days - ` 2,500/- One Day - ` 1,250/- PG Students ` 1,500/- LATE REGISTRATION ( Till 3 February, 2012) Consultants - Both Days - ` 3,000/- One Day - ` 1,500/- SPOT REGISTRATION Consultants - Both Days - ` 3,500/- One Day - ` 2,000/- MEET THE EXPERTS ` 500/- *Registration does not include accommodation. Mala Arora Mandakini Parihar Manish Banker Mirudhubashini Govindarajan Nandita Palshetkar Nalini Mahajan Nirmala R Nivedita Shetty Padmarekha Jirge Reeta Biliangady Satish Adiga Shobhana Patted Sharath Kumar C Shreyas Padgaonkar Sonia Malik Srinivas MS Sunita Tandulwadkar Vyjayanthi Organizing Committee PATRONS Dr. Kamini Rao Dr. Sulochana Gunasheela Dr. Pratap Kumar SCIENTIFIC COMMITTEE Dr. Kamini Rao Dr. Madhuri Patil Dr. Reeta Biliangady FINANCE Dr.Bina Vasan Dr. C Sharath Kumar Dr. Devika Gunasheela CATERING COMMITTEE Dr. Jyoti Menon Dr. Kallappa Mavintop Dr. Sowmya Dinesh TRAVEL/TRANSPORT/ ACCOMMODATION Dr. Srinivas MS Dr. B R Desai Dr. Shobhana Patted REGISTRATION COMMITTEE Dr. Nirmala R Dr. Asha Gangane Dr. Puneeth Rangaraj AUDIOVISUAL Dr. Madhuri Patil Dr. Satish Adiga Dr. Varsha Roy TRADE & EXHIBITION Dr. B. Ramesh Dr. Vanitha Metgud Dr. Rajesh Bhaktha FREE PAPERS Dr. SS Vasan Dr. Roopa Send in your Poster Topic: Ovarian Stimulation Last Date for Submission 25th January, 2012 Abstracts to be e-mailed to kisar.office@gmail.com drmadhuripatil59@gmail.com Instructions for Poster presentation: Maximum Size of poster should be 3 feet wide and 4 feet in height Poster should be put up by 9 AM on 4th February 2012 One person can present only 1 poster Presenters have to be present at the specified time announced during the conference for judging Posters should be removed by 5.30 PM on 5th February 2012 Best 3 posters will be allowed oral presentation for 8 minutes on 4th February between 3.30 4.00 PM