Surgical Oncology/Clinical Center Sarajevo - Sarajevo, Bosnia and Herzegovina

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- Sarajevo, Bosnia and Herzegovina General Information New breast cancer cases treated per year 200 Breast multidisciplinarity team members 24 Radiologists, surgeons, pathologists, medical oncologists, radiotherapists and nurses Clinical Director: Šefik Bešlic, MD The full name of the Clinic is 'Oncology and Glandular Surgery Clinic'. At the beginning, in 1956, the Clinic was made up of just the surgery division that then became wards and department. Since then, the Clinic has been evaluated in many ways, treating patients even during the three and a half year long siege of the city of Sarajevo. After the new organization of our Clinical center, the Clinic was transferred to the location of Old Surgery where it is based now. Since 2003, Primaries Dr. Šefik Bešlic has been nominated as the Head of the Clinic and the Clinic itself, along with all previous activities, has developed its range of operational treatments regarding oncology surgery. Within the Clinic there are two standard patient wards with 29 beds, half intensive care department and one suit. For outpatients we have a specialist ambulance for examinations. Clinic has its own operational theatre with corresponding equipment. Surgical Oncology/Clinical Center Sarajevo Bolnicka 25 71000 Sarajevo, Bosnia and Herzegovina Phone: +38733297555 Fax: +38733258431 E-mail: hironkc8@gmail.com Web-site: www.kcus.ba 1/6

Available services Reconstructive/Plastic Surgery Nuclear Medicine Rehabilitation Genetic Counselling Data Management Psycho-oncology Breast Nurses Social Workers Nutritional Counselling Survivorship Groups Sexual Health Counselling Supportive and Palliative Care Integrative Medicine Dedicated Radiologists 1 Mammograms per year 2000 Breast radiographers Screening program Verification for non-palpable breast lesions on specimen Axillary US/US-guided FNAB Available imaging equipment Mammography Ultrasound Magnetic Resonance Imaging (MRI) Available work-up imaging equipment Computer Tomography Ultrasound Magnetic Resonance Imaging (MRI) PET/CT scan Primary technique for localizing non-palpable lesions Hook-wire (or needle localization) Charcoal marking/tattooing ROLL: radio-guided occult lesion localization Available breast tissue sampling equipment Stereotactic Biopsy (Mammography guided) Core Biopsy (Tru-cut) Vacuum assisted biopsy Ultrasound-guided biopsy Fine-needle aspiration biopsy (FNAB, cytology) Core Biopsy Vacuum assisted biopsy MRI-guided biopsy Core Biopsy Vacuum assisted biopsy New operated cases per year (benign and malignant) 420 Dedicated Breast Surgeons 6 Surgeons with more than 50 surgeries per year 3 beds 29 Breast Nurse specialists 15 Outpatient surgery Intra-operative evaluation of sentinel node Reconstruction performed by Breast Surgeons Primary technique for staging the axilla Axillary lymph node dissection Sentinel lymph node biopsy: Blue dye technique Radio-tracer technique Blue dye + Radio-tracer Axillary sampling 2/6

Reconstructive/Plastic Surgery Reconstructive/Plastic surgeons 2 Immediate Reconstruction available Type of breast reconstructive surgery available Remodelling after breast-conserving surgery Reconstruction after mastectomy: Two-stage reconstruction (tissue expander followed by implant) One-stage reconstruction Autogenous tissue flap Latissimus dorsi flap Transverse rectus abdominis (TRAM) Free-flaps (free TRAM, DIEP, SIEA, gluteal, etc.) Surgery on the contralateral breast for symmetry Dedicated Breast Pathologists 1 Available studies Cytology Haematoxylin & eosin section (H&E) Surgical specimen Sentinel node Core biopsy Frozen section (FS) Surgical specimen Sentinel node Immunohistochemistry stain (IHC) Estrogen receptors Progesterone receptors HER-2 Ki-67 Other special studies available Fluorescence in-situ Hybridization for HER-2 gene (FISH) Oncotype Dx (21-gene assay) MammaPrint (70-gene microarray) Prediction Analysis of Microarray 50-gene set (PAM 50) Parameters included in the final pathology report stage (pt and pn) Tumour size (invasive component in mm) Histologic type Tumor grade ER/PR receptor status HER-2/neu receptor status Peritumoural/Lymphovascular invasion Margin status Dedicated Breast Medical Oncologists 3 Outpatient systemic therapy 3/6

Dedicated Radiation Oncologists Available techniques after breast-conserving surgery (including experimental) Whole-Breast RT (WBRT) Partial breast irradiation (PBI): External beam PBI Interstitial brachytherapy Targeted brachytherapy (MammoSite, SAVI applicator, other devices) Intra-operative RT (IORT) Multidisciplinary Meeting (MDM) / Tumour Board (TB) Regular MDM/TB for case management discussion Twice a week Weekly Every two weeks Other Schedule Cases discussed at MDM/TB Preoperative cases Postoperative cases Specialties/services participating in MDM/TB Reconstructive/Plastic Surgery Genetic Counselling Breast Nurse Service Psycho-oncology Further Services and Facilities Nuclear Medicine Lymphoscintigraphy Bone scan Positron Emission Tomography (PET) PET/CT scan Rehabilitation Prosthesis service Physiotherapy Lymph-oedema treatment Genetic Counselling Specialist Providing Genetic Counselling/Risk assessment service: Dedicated Clinical Geneticist Medical Oncologist Breast Surgeon General Surgeon Gynaecologist Genetic Testing available Surveillance program for high-risk women Data Management Database used for clinical information Data manager available 4/6

Contact details Clinical Director Šefik Bešlic, MD Head of the Clinic beslics1@bih.net.ba +38733258430 Vanesa Beslagic, MD Radiologist vanesab@bih.net.ba Emir Bicakcic, MD Surgery Resident ebicakcic@gmail.com +38761257824 Reconstructive Surgery Alija Agincic, MD Plastic Surgeon agal@bih.net.ba +38761173703 Nurija Bilalovic, PhD Pathologist nurija62@gmail.com +38761184453 Timur Ceric, MD Oncology Resident timur_ceric@yahoo.com +38761260021 Mirela Kalamujic, MD Radiation Oncologist mkalamujic@yahoo.com 5/6

How to reach us Surgical Oncology/Clinical Center Sarajevo Bolnicka 25 71000 Sarajevo, Bosnia and Herzegovina Phone: +38733297555 Fax: +38733258431 E-mail: hironkc8@gmail.com Web-site: www.kcus.ba From airport: At Sarajevo airport take a taxi to reach the Clinical Center (30 min). By train: Railway station is located close to the Clinical center (15 min. walk or take a taxi). By bus or sub-way/underground: Bus number 14 and 17 will take you directly from the city center to the Clinical Center. By car: Arriving from Zenica (Northwest) take Alipašina street, then turn left to Bolnicka st. Direction Mostar (west) take Meša Selimovic blvd. and straight ahead to Zmaja od Bosne, Hiseta st. turn left in Alipašina st. and then turn right to Bolnicka st. Last modified: 22 January 2016 6/6