Opioid Deaths in South Carolina. Daniela Nitcheva, PhD Division of Biostatistics Bureau of Public Health Statistics

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Opioid Deaths in South Carolina Daniela Nitcheva, PhD Division of Biostatistics Bureau of Public Health Statistics

Death Certificates

ICD-10 Codes Literal text for cause of death is sent to the National Center for Health Statistics (NCHS) NCHS codes cause of death according to ICD- 10 rules NCHS returns codes to the state ICD-10 codes are used to calculate statistics

Drug Overdose Deaths by Intent, SC, 2007-2016 Occurrence Data Number of deaths 1000 900 800 700 600 500 400 300 544 445 SC Drug Overdose Deaths Unintentional Drug Overdose Deaths Suicide by Drug Overdose 569 485 617 547 679 577 587 573 489 478 613 528 718 629 789 713 876 785 200 100 79 74 64 91 85 80 74 74 66 76 0 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

Opioid Deaths, 2016 876 drug overdose deaths occurred in SC, up from 789 deaths in 2015 (11% increase) 616 deaths involved opioids, up from 565 in 2015 (9% increase) 70.3% of all drug overdose deaths involved opioids

Multiple drugs Often deaths involve more than one drug; such deaths are included in more than one category. Therefore, categories of drugs are not mutually exclusive and the numbers do not add up to the total.

Opioid Deaths, 2015-2016 Drug/Category 2015 2016 Percent change Total opioids 565 616 9% Prescription opioids 512 550 7% Fentanyl 130 190 46% Heroin 95 108 17%

Opioid Deaths by Age, South Carolina, 2014-2016, Occurrence data 65 + 19 21 27 2016 2015 2014 55-64 101 108 107 45-54 152 145 142 Age 35-44 25-34 83 117 116 136 136 153 18-24 31 36 50 0-17 5 1 3 0 20 40 60 80 100 120 140 160 180 Number of deaths

Opioid Deaths by Race/Sex, South Carolina, 2014-2016, Occurrence data White Female 35% Black and Other Male 4% Black and Other Female 3% White Male 58%

Email: info@dhec.sc.gov Phone: (803) 898-DHEC (3432) Media Relations Media Contact Information Email: media@dhec.sc.gov

South Carolina Department of Alcohol and Other Drug Abuse Services Opioid Related Treatment in South Carolina Andrew Fogner, MSPH Epidemiologist

South Carolina Department of Alcohol and Other Drug Abuse Services Objectives Historical Admission Rates Total Patient Count Percentage of Patients with Opioid related Problem Geographic/Demographic Breakdown Route of Administration

South Carolina Department of Alcohol and Other Drug Abuse Services Opiates Admissions Trend Number of Opiates Admissions by Calendar Year Opiates = Primary Problem Opiates =Prim, Sec, or Tert 4,500 4,122 4,000 3,500 3,014 3,366 3,467 3,713 3,000 2,500 2,000 1,500 1,934 1,945 1,391 1,360 2,263 2,469 1,494 1,498 2,598 1,668 2,002 2,175 2,329 2,524 2,792 1,000 500 0 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 Calendar Year

Substance Use Category South Carolina Department of Alcohol and Other Drug Abuse Services FY17 Total Patient % 2016 07 2016 08 2016 09 % of Total Unduplicated Patient Count 2016 10 2016 11 SFY Total Any Opiate Problem Type* 17% 16% 17% 15% 17% 18% 18% 16% 15% 18% 17% 19% 17% Primary Problem Type = Heroin 6% 5% 5% 4% 5% 5% 5% 4% 5% 5% 6% 6% 5% Any Problem Type = Heroin 7% 6% 7% 6% 7% 7% 7% 6% 6% 7% 8% 8% 7% Primary Problem Type = Other Opiates 6% 6% 6% 5% 6% 6% 7% 7% 5% 7% 6% 7% 6% Any Problem Type = Other Opiates 12% 12% 12% 11% 12% 13% 14% 13% 11% 13% 12% 14% 12% Any Injection Use Mentioned** 3% 2% 3% 3% 3% 2% 3% 3% 2% 3% 3% 3% 3% Past 30 Day Injection Use Mentioned 2% 2% 2% 2% 2% 2% 2% 2% 2% 2% 2% 2% 2% 2016 12 * Any Opiate Problem = Heroin, Methadone, and Other Opiates and Synthetics ** Any Injection use and past 30 day injection use includes injection of non opiate substances 2017 01 2017 02 2017 03 2017 04 2017 05 2017 06

Substance Use Category South Carolina Department of Alcohol and Other Drug Abuse Services FY17 Patient % with Opiate Problem % of Total of Unduplicated Patients Reporting Opiate Problem Types 2016 07 2016 08 2016 09 2016 10 2016 11 2016 12 2017 01 2017 02 2017 03 2017 04 2017 05 2017 06 SFY Total Primary Problem Type = Heroin 33% 29% 29% 28% 29% 31% 28% 27% 31% 29% 36% 31% 30% Any Problem Type = Heroin 44% 38% 40% 39% 38% 41% 39% 37% 40% 41% 47% 43% 40% Primary Problem Type = Other Opiates 35% 36% 36% 34% 37% 34% 38% 41% 35% 37% 33% 37% 36% Any Problem Type = Other Opiates 71% 74% 73% 72% 72% 74% 75% 78% 76% 73% 71% 73% 74% Any Injection Use Mentioned** 16% 16% 16% 17% 18% 14% 18% 16% 15% 18% 16% 17% 16% Past 30 Day Injection Use Mentioned 12% 10% 12% 10% 13% 9% 11% 9% 10% 11% 11% 10% 11% * Any Opiate Problem = Heroin, Methadone, and Other Opiates and Synthetics ** Any Injection use and past 30 day injection use includes injection of non opiate substances

South Carolina Department of Alcohol and Other Drug Abuse Services FY17 % Distribution of Patients Total Unduplicated % Opiate Related Agency Admissions Admissions York 2,026 28.1% Charleston 2,652 28.0% Colleton 360 24.7% Greenville 4,286 23.9% Florence 1,300 20.2% Horry 2,044 19.5% Georgetown 352 18.5% Williamsburg 301 18.3% LRADAC 4,213 18.1% Lancaster 437 17.6% Spartanburg 1,803 16.9% State Average 35,028 16.8% 30.0% 25.0% 20.0% 15.0% 10.0% 5.0% 0.0% 28.1% 28.0% 24.7% 23.9% 20.2% 19.5% 18.5% 18.3%18.1% 17.6% 16.9%16.8%

South Carolina Department of Alcohol and Other Drug Abuse Services FY17 Total Opiate Problem FY17 Gender FY17 Race 9% 3% 52% 48% Male 88% White Black Female Other 44% of patients with an opiate related problem are between the ages of 25 34.

South Carolina Department of Alcohol and Other Drug Abuse Services FY17 Opiate Problem Type by Route of Administration Inhalation Injection Oral Other Smoking Unknown Total # of Opiate Admissions 858 1,923 2,862 20 48 15 5,726 Avg. Age in Years at Admission 32.95 32.47 35.35 32.95 32.09 31.88 33.98 % Male 55.0% 54.3% 46.4% 50.0% 47.9% 40.0% 50.3% % White 85.4% 92.3% 85.7% 85.0% 83.3% 60.0% 87.8% % Hispanic 5.1% 4.9% 5.1% 0.0% 6.3% 6.7% 5.0% % CJ System Referral 15.2% 15.1% 23.8% 40.0% 25.0% 20.0% 19.6% % Social Services Referral 16.2% 11.5% 23.3% 5.0% 16.7% 46.7% 18.2% % Self Referral 53.0% 61.0% 35.8% 45.0% 47.9% 13.3% 46.9% % Employed Full or Part Time 35.7% 26.7% 33.9% 45.0% 27.1% 26.7% 31.7% % Homeless 6.3% 8.8% 3.0% 0.0% 10.4% 0.0% 5.5% Source: South Carolina Department of Alcohol and Other Drug Abuse Public Substance Use Disorder Treatment System * Admission counts presented in table represent distinct treatment episodes for 5,002 unduplicated individuals

South Carolina Department of Alcohol and Other Drug Abuse Services CONTACT US Physical Address: 1801 Main Street, 4th Floor Columbia, SC 29201 Phone: 803.896.5555 www.daodas.sc.gov

South Carolina Opioid Epidemic Khosrow Heidari Senior Epidemiologist Prescription Monitoring Program, Bureau of Drug Control Sept. 7 TH 12:35pm 1:05pm, Lexington A Ballroom

Objectives: How bad is the opioid epidemic? Any mortality and morbidity? Factors impacting opioid epidemic? What is DHEC doing to reduce the burden of opioid epidemic?

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 1999 Drug-poisoning deaths are defined as having ICD 10 underlying cause-of-death codes X40 X44* (unintentional) Source: https://blogs.cdc.gov/nchs-data-visualization/drug-poisoning-mortality/ *Accidental poisoning by and exposure to drugs and other biological substances

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2000

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2001

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2002

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2003

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2004

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2005

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2006

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2007

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2008

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2009

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2010

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2011

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2012

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2013

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2014

Estimated Age-adjusted Death Rates for Drug Poisoning by County, 2015

EMS, Monthly Suspected Opioid Overdose Rescue Cases, South Carolina 2014- Mid 2017 600 500 400 300 200 100 0 Jun, 2017 Jan, 2014 Feb, 2014 Mar, 2014 Apr, 2014 May, 2014 Jun, 2014 Jul, 2014 Aug, 2014 Sep, 2014 Oct, 2014 Nov, 2014 Dec, 2014 Jan, 2015 Feb, 2015 Mar, 2015 Apr, 2015 May, 2015 Jun, 2015 Jul, 2015 Aug, 2015 Sep, 2015 Oct, 2015 Nov, 2015 Dec, 2015 Jan, 2016 Feb, 2016 Mar, 2016 Apr, 2016 May, 2016 Jun, 2016 Jul, 2016 Aug, 2016 Sep, 2016 Oct, 2016 Nov, 2016 Dec, 2016 Jan, 2017 Feb, 2017 Mar, 2017 Apr, 2017 May, 2017 Number of Rescue Cases Source: South Carolina Department of Health and Environmental Control, Bureau of Emergency Medical Services (EMS). Accessed August 10, 2017

South Carolina Drug Overdose Morbidity (Emergency Department and Hospitalization Visit) Rates 160 140 AGE ADJUSTED MORBIDITY RATE (PER 100,000) 120 100 80 60 40 20 2013 2014 2015 2016* 0 ED VISIT: ALL DRUG Source: RFA- Health and Demographics * 2016 Data is preliminary ED VISIT: OPIOIDS EXCLUDING HEROIN ED VISIT: HEROIN HOSPITALIZATION: ALL DRUG HOSPITALIZATION: OPIOIDS EXCLUDING HEROIN HOSPITALIZATION: HEROIN

SC Rate of opioid Analgesics per 1,000 state Residents 1000 Opioid Rx 950 932 948 900 850 841 859 849 894 800 797 750 700 2010 2011 2012 2013 2014 2015 2016 Source: DHEC SCRIPTS Analysis by MUSC

Percentage of Patients receiving 90 MME of Opioid Analgesics 10 9 8 7 6 5 4 3 2 1 0 Q4 Q3 Q2 Q1 Q4 Q3 Q2 Q1 Q4 Q3 Q2 Q1 Q4 Q3 Q2 Q1 Q4 Q3 Q2 Q1 Q4 Q3 Q2 Q1 2011 2012 2013 2014 2015 2016 Source: DHEC SCRIPTS Analysis by MUSC

Summary Opioid crisis is in its epidemic stage: Increased overdose death (num. and rates), Increased overdose incidence and rescue, Increased ED and hospitalization Prescription medication has been increasing over the last decade The percent of patient receiving high dosage of opioid ( 90 MME) has been declining.