Beck depression inventory in general practice

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Beck depression inventory in general practice M. R. SALKIND, M.R.C.S., L.R.C.P., M.R.C.G.P. London THE early diagnosis of depression has become increasingly important to family doctors. The majority of depressions which come to the notice of doctors in the United Kingdom are now solely treated by general practitioners (Rawnseley) and family doctors are still the only effective screening agents. Additionally, the impetus towards the involvement of general practitioners in clinical research is gaining momentum. In the psychiatric field they are concerned not only with the identification of the early depressive, but they are now participating in the clinical evaluation of new products, the comparison of existing antidepressants and the serial evaluation -of patient's moods, alongside many other lines of enquiry. An objective assessment of depression, valid in general practice is therefore of importance, and the current study is an attempt to remedy the absence of published validation studies in the general practice field. The Beck Depression Inventory provides a self-rating measurement of the behavioural manifestations of depression (Beck et al.) and consequently promises to be a useful and accurate research instrument, especially valuable in multicentre trials since it bypasses the clinician's subjective bias. For use in general practice a method requires to be easily answered, easily applied by a clinician, easily and rapidly scored; it should be accurate and reliable. The BDI fulfils these requirements more closely than other existing scales. It can be completed by the patient in a few minutes and can be scored easily. The MMPI was not designed specifically for the measurement of depression. It uses outdated psychiatric nomenclature, and factor analytic studies (Comrey) show that the depression scale contains a number of heterogenous factors only one of which is consistent with the clinical concept of depression. The Hamilton rating although fairly concise and sensitive (Dunlop), does not have a 'cutting score'; is more time consuming to apply and score; and is not self-rating. Whilst self-rating scales have obvious deficiencies and defects, the BDI appears to possess a high degree of validity when compared with clinical assessments made by four American psychiatrists (Beck et al.). It has been validated in hospital in Britain (Metcalfe and Goldman), who reported the "DI (Beck) has proved a simple and satisfactory method of assessing the level of depression in patients suffering from depressive illnesses... and should provide a numerical score which could be compared with other quantitive data". Their study, however, was confined to clinically-diagnosed depressives in the hospital. Some care must be taken in interpretation of these results since only 37 patients were used to yield 120 ratings (taken at intervals during hospital stay). A more interesting comparison with the present study is the application of the BDI to 153 general medical inpatients in an American hospital (Schwab et al.). This sample, like the general-practitioner sample, was composed of patients with organic illnesses who were not selected for psychiatric disorders. Of this group 34 of 153 (22 per cent) were provisionally diagnosed as depressed by various members of the medical staff and of these 34 only eight (24 per cent) had BDI scores of 14 or more. Schwab suggests that the 'cutting score' of 10 is a suitable demarcation point since of the 34 patients who were clinically depressed 47 per cent scored 10-13 and 74 per cent of those diagnosed as clinically depressed had a score of 10 or above. Method In this study a serial sample was taken. The first 80 patients coming into the consulting room were asked to complete the BDI. J. ROY. COLL. GEN. PRAC1TI., 1969, 18, 267

268 M. R. SALKTND The Beck depression inventory The BDI consists of a list of descriptive statements related to 21 aspects of depression. For each category there are 4-5 statements of increasing severity. The patient reads the scale and marks the statement most applicable himself. The to score for each item ranges from 0-3; the total score falls between 0-62. All 80 patients requested an item of service ranging from a repeat prescription, to a complete physical check-up. One patient refused on the grounds of time. One patient was unable to fil out the scale. It transpired that she was unable to read or write. Five were spoiled for various reasons. (With more care all five need not have been spoiled.) Most patients were able to complete the questionnaire without difficulty. It was handed to the receptionist and the patient then entered the consulting room and was interviewed and treated in the normal way. A forecast was then made for each patient on the following 4-point rating scale: 0 No depression. Mild depression, i.e. symptoms, but no interference with work or sociallife. 2 Moderate depression. Some but not considerable interference with work or social life. 3 Suicidal, or severe interference with work or social life extending into inability to work. This forecast was then transferred to the completed questionnaire which was sent to an independent observer for scoring and analysis. Cutting score In the context of results the exact cut-off point is critical. Schwab in his series on general medical inpatients felt that10 was an appropriate 'cutting score' for distinguishing between non-depressed and depressed patients; i.e. scores of 10 and above, denote depression. He quotes a personal communication from Beck (1963) stating that minimally depressed or non-depressed patients score 0-13, mild to moderate 14-24, 10 severely depressed 25+. His results at a cut-offof correlated highly with the Hamilton scale. Beck in his original paper, and Metcalfe, both dealing with a wholly depressed population suggest a 'cutting score' of 17 (Spearman Rank Correlation 0.75). One would expect a higher cut-off point in a depressed population than in a random sample in general practice, where fine variations are more evident in the normal social setting and are easier to detect. Results From the figures in tables I and II it is apparent that there is a significant difference between the non-depressives and the remainder(p=00.0). There is not so great a significance between the means for scores one and two, (just significant at the 5 per cent level). The optimum cut-off point in the general-practice field would appear to be11, a higher score denoting depression. This corresponds well with Schwab, slightly lower than Beck 1963 (0-13), significantly lower than Metcalfe, and is lower than Beck's original paper (1960)suggested. A 'cutting score' of11 would appear reasonable because of the finer differences observable in general practice and would answer the question raised in the OHE publication The early diagnosis of depression-"the appropriate 'cutting scores' to allow optimum discrimination between patients with and without depression would require further research in the general practice setting". It would appear that in general practice therefore, the appropriate scores would be: No depression 0-lO Mild depression 11-17 Moderate depression 18-23 Severe depression 23 and above On a 'cutting score' of 11 it appears that 48 per cent of patients presenting in a general practitioner's surgery,rcould be classified as being in a depressed state. This is

BECK DEPRESSION INVENTORY IN GENERAL PRACTICE TABLE I INDIVIDUAL SCORES ON BECK DEPRESSION INVENTORY 269 Clinician's Beck score Clinician's Beck score forecast score forecast score 0=No depression 0 4 7 10 cut-off 2= Moderate 5 cut-off 19 0 4 8 11 depression 11 19 1 5 8 11 14 19 Number of 1 5 8 13 14 20 patients-38 2 5 8 13 Number of 14 24 2 5 9 13 patients-16 16 26 2 6 9 17 16 26 3 6 9 19 16 4 6 10 16 4 7 10 1=Mild 7 13 3 =Severe depression 7 13 depression 26 7 14 Number of Number of 8 cut-off 15 patients-2 30 patients- 17 11 19 1 1 22 12 22 12 28 12 L TABLE II MEANS AND SD FOR SALKIND COMPARED TO OTHERS No depression Mild Moderate Severe score 0 score 1 score 2 score 3 Mean SD Mean SD Mean SD Mean SD Salkind.... 66 4-2 137 59 17.2 54 28-0 2-8 Metcalfe.... 5-4 59 14-3 8-4 24*2 10.8 29-5 6-5 American study (Beck).... 10-9 81 18*7 10*2 25.4 9-6 30.0 10.6 Schwab.... 91 - - Mean 11-8 -- SD 5-5 -* clearly to be differentiated from those suffering from a depressive illness. Even so, given that this is an isolated result, and that a doctor with an interest in the psychiatric side of general practice might well attract a higher proportion of patients with psychiatric disorders, this is a figure which by any standards is startling. TABLE III The practice concerned is in an area populated by social groups IV and V and the high depression figures could be partially accounted for by Schwab's demographic observation "the only significant difference between these groups is concerned with their financial status; most of the scores on the BDI were given by patients of lower economic levels!" UORRELATION CO-EFFICIENT BETWEEN -U- F-II -Tt BDI AND IT FORECAST (RATING) OF DEPTH OF DEPRESSION Study Correlation co-efficient Salkind...73 Beck.... *66 Metcalfe.. *62

270 M. R. SALKIND A figure of this level clearly requires further investigation. If it is in any way representative of the total patient population, then re-evaluation of the scale of depression in the community, already known to be considerable (Watts, 1966), is an urgent necessity. Table IV is self explanatory. Pessimism, sleep disturbance, fatiguability, lack of satisfaction, self accusation and a mood disturbance allied to a sense of failure, form TABLE IV NUMBER OF PATIENTS MARKING THE APPROPRIATE SECTION IN A WAY +VE FOR DEPRESSION IN ORDER OF PRIORITY Patients not depressed Depressed patients Irritability...... 24 Sleep disturbance.... 31 Fatiguability...... 22 Pessimism.... 31 Sleep disturbance.. 18 Irritability.... 30 Work inhibition.. 14 Fatiguability.... 29 Somatic preoccupation 11 Lack of satisfaction.... 28 Loss of libido...... 9 Self accusations.... 27 Self accusations.. 8 Mood.... 25 Lack of satisfaction.. 8 Sense of failure.... 25 Social withdrawal.... 6 Self hate...... 23 Crying...... 6 Indecisiveness...... 23 Loss of appetite.... 6 Work inhibition.... 23 Weight loss...... 6 Crying..... 22 Body image...... 5 Somatic preoccupation.. 19 Pessimism...... 4 Loss of libido...... 17 Mood...... 3 Social withdrawal.. 15 Sense of failure.... 3 Body image...... 15 Sense of punishment.. 3 Self punitive.... 13 Indecisiveness...... 3 Sense of punishment.. 12 Self hate...... 2 Guilty feeling...... 10 Guilty feeling...... 0 Loss of appetite.. 10 Self punitive...... 0 Weight loss...... 8 a diagnostic group in themselves. Of the 43 non-depressed patients 24 were positive for increased irritability, as were 30 of the depressed group-(i.e. 54 out of 73). The TABLE V DISTRIBUTION OF PATIENTS' SCORES ON GIVEN CUTTING SCORES (EXPRESSED AS PERCENTAGES) No Number of Study depression Mild Moderate Severe Total patients Salkind: General medical patients.... 52 23 22 3 100 73 Beck: American study psychiatric inpatients 28 31 33 8 100 409 Metcalfe and Goldman: psychiatric inpatients.. 27 37 20 17 100 120 (ratings not patients) Schwab...... 78 22 -* 100 153 Prov. diagnosed

BECK DEPRESSION INVENTORY IN GENERAL PRACTICE 271 total of 26 out of 73 patients admitting to some loss of libido is also of interest and merits further investigation. Discussion It would appear from these results that the BDI is indeed an acceptable objective instrument capable of refined assessment of depression in general practice; easy to apply and score; suitable for clinical trials, particularly multi-centre trials. It can be used to standardize criteria for entry to a trial as well as for serial evaluation of progress. It can reveal depressions hidden from the clinician. (In the current survey one misdiagnosis was a forecast of 0 depression in a patient who subsequently was found to have a score of 19. It transpired on special interview that he was a withdrawn patient, unquestionably depressed but withdrawn to the extent that he was unable to communicate his depression). It would seem therefore, to be a suitable screening aid, and a useful diagnostic aid in clinically doubtful cases. It has raised at least one basic question. What is the true extent of all grades of depressive illness-(not only severe depressive illness)-in our community? Acknowledgements I acknowledge with thanks the help of Mr Donald Hills and Mr J. Olivant of Delandale Laboratories for the supply of the Beck Depression Inventories, and to Dr S. Buck for statistical analysis. I am grateful to Miss Margaret Hammond of The Royal College of General Practitioners, for her usual unfailing assistance and to Mrs G. Slipper for her help with the administrative side of the study. REFERENCES Beck, A. T., et al. (1961). Arch. gen. Psychiat. 4, 561. Cornrey, A. L. (1957). Educ. Psychol. Meas. 17, 578. D'unlop, E. (1966). Proceedings of the first internal symposium on antidepressant drugs. p. 316. Massachusetts. Fuller. Hamilton, M. (1960). J. Neurol. Neurosurg. Psychiat. 23, 56. Metcalfe, M, and Goldman E. (1965).. Brit. J. Psychiat. 111, 240. Rawnseley, K. (1968). The early diagnosis of depression. OHE Early Diagnosis. Paper 4. Schwab, J., et al. (1967). Acta Psychiat Scand. 255. Watts, C. A. H. (1966). Depressive disorders in the community. Bristol. J. Wright & Son. General practice today Not a week goes by, in general practice, without the doctor discovering amongst his morning mail yet another regular newspaper or journal orientated towards general practice and sent free of charge. The majority of these publications, some of them quite valuable, are financed by the big pharmaceutical firms as an advertising medium. Our own abstract journal, in a sense, is in the same category. In these publications, at which I am sure the average general practitioner has only time to glance, there are an increasing number of articles written on the manner in which the delivery of primary care should be organized and delivered to the public in the future. Authors vary from general practitioners to doctors working along the fringes (e.g. in social medicine) of the real situation, rarely coping with the heavy winter evening surgery and carrying out the arduous winter visit list. Not enough views are heard from the practitioner in the front line of the delivery of this primary medical care because he is so involved in meeting the 'service' demands that he has not the time to sit back, think and plan the operational research which should yield the facts necessary for the proper planning of medical care 20 years on. Most would agree that those who say that the general practitioner is on the way out are absolutely wrong. With the continuing rapid growth of knowledge and, therefore, the need for greater specialization, it is absolutely essential that there should be not only a generalist but a generalist with a high degree of training and skill for his particular role in the delivery of this scientific medical care that will be available in the future. The plans of our College for vocational training for general practice are, therefore, particularly welcome and relevant, in spite of difficulties that the implementation of such a policy may arouse initially. Current Medical Abstracts for Practitioners. 1968. 8, 68.