International Workshop on Developmental Nephrology 15th International Workshop on Developmental Nephrology Sunday, April 22 nd - Thursday, April 26 th, 20158 Ein Gedi Hotel, The Dead Sea Tel Aviv, Israel Chair: Dr. Gregory Dressler Co-Chair: Dr. Benjamin Dekel Coordinator: Juliet Rodrigo Contact: juliet.rodrigo@uhn.ca ~ Workshop Agenda ~ Sunday, April 22 th, 2018 Arrive at Ein Gedi Hotel Evening Opening Reception: 6:00-10:00pm Registration Desk: 6:00-10:00pm
Monday, April 23 th, 2018 7:00-8:00 Breakfast at Hotel Restaurant Registration Desk (until 8:15am) 8:15-8:30 Welcome Introduction 8:30-12:00 Session I: Nephrogenesis and Early Development Moderator: M. Rauchman 8:30-8:50 Thomas Schultheiss Aorta-Gonad-Mesonephros 8:50-9:10 Nils Lindstrom Nephron patterning in the human kidney 9:10-9:30 Silvia Cereghini 9:30-9:50 Thomas Carroll 9:50-10:10 Michael Rauchman Regulate of nephron progenitor cell fate and formation of the loop of Henle 10:10-10:30 Break 20 minutes 10:30-10:50 Alan Davidson Formation of the zebrafish kidney: from mesoderm to nephron 10:50-11:10 Helen McNeil Fat/Hippo signaling in Kidney development 11:10-12:00 State-of-the-Art Lecture Raphael Kopan Director, Division of Developmental Biology, Cincinnati Children s, Ohio, USA <TITLE> 12:00-1:00 Lunch International Workshop on Developmental Nephrology Agenda Page 2
1:00-3:00 Session II: Glomerular and Vascular Development and Disease Moderator: K. Skorecki 1:00-1:20 Maria Luisa Sequeira Lopez 1:20-1:40 Rachel Lennon Changes in extracellular matrix during glomerular development 1:40-2:00 Susan Quaggin 2:00-2:20 Jacqueline Ho MicroRNAs and kidney development 2:20-2:40 Katlin Susztak 2:40-3:00 Denise Marciano Novel mechanisms of glomerular development 3:00-3:20 Break 20 minutes 3:20-5:40 Session III: Stem Cells and Reprogramming Moderator: B. Dekel 3:20-3:40 Andy McMahon 3:40-4:00 Oliver Wessely The differentiation of human stem cells into renal cell lineages 4:00-4:20 Jordan Kreidberg 4:20-4:40 Zubaida Saifudeed Nephron progenitor cell metabolism and fate 4:40-5:00 Kenji Osafune Prospective isolation of human nephron progenitors 5:00-5:20 Samir El Dahr Chromatin states of nephron progenitors 5:20-5:40 Naomi Pode-Shakked 6:00-7:30 Dinner International Workshop on Developmental Nephrology Agenda Page 3
7:30-9:00 Poster Session and Discussion Poster Session One (1): First Name Last Name Title International Workshop on Developmental Nephrology Agenda Page 4
Tuesday, April 24 th, 2018 6:30 Early Breakfast 7:00-11:00 Morning Trip to Massada Event Details: 7:00 Shuttle bus to leave for Massada 7:30 Arrive at destination 8:00 Massada Cable Car Operation Opening 10:30 Shuttle bus to leave for return to venue 11:00 Arrive Venue 11:30-12:30 Lunch 1:00-1:50 State-of-the-Art Lecture Haim Cedar Chairperson, Developmental Biology & Cancer Research, IMRIC Harry and Helen L. Brenner Professor of Molecular Biology <TITLE> 1:50-6:10 Session IV: Bioengineering Kidneys and Applications Moderator: D. Hoshazaki 1:50-2:10 Melissa Little Evaluating differentiation within human pluripotent stem-cell derived kidney organoids 2:10-2:30 Ben Freedman 2:30-2:50 Seppo Vainio 2:50-3:10 Neil Hukriede Elucidating the Cellular Mechanisms of a Pro-regenerative Drug Therapy for AKI 3:10-3:30 Joe Bonventre 3:30-3:50 Soeren Lienkamp 4:00-6:00 GUDMAP Workshop (walk in session) Presenter: T. Valerius 6:30-7:30 Dinner International Workshop on Developmental Nephrology Agenda Page 5
7:30-9:00 Poster Session and Discussion Poster Session Two (2): First Name Last Name Title International Workshop on Developmental Nephrology Agenda Page 6
7:00-8:00 Continental Breakfast Wednesday, April 25 th, 2018 8:30-12:00 Session V: Urinary Tract Development and Disease Moderator: G. Dressler 8:30-8:50 Norm Rosenblum 8:50-9:10 Cathy Mendelsohn Molecular pathways regulating urothelial formation and regeneration 9:10-9:30 Andreas Kispert Ureter Development 9:30-9:50 Maxime Bouchard Apoptotic cell death in ureter maturation 9:50-10:10 Carl Bates Novel links between Fgf signaling and metabolism in nephron progenitors 10:10-10:30 Adrian Woolf 10:30-10:50 Break 20 minutes 10:50-11:10 Jon Barasch 11:10-11:30 <ABSTRACT> 11:30-11:50 <ABSTRACT> 11:50-12:10 <ABSTRACT> 12:10-1:30 Lunch 1:30-3:30 Session VI: Human Congenital Abnormalities Moderator: E. Avner 1:30-1:50 Friedhelm Hildebrandt Monogenic causes of CAKUT delineate pathogenic pathways International Workshop on Developmental Nephrology Agenda Page 7
1:50-2:10 Indra Gupta Genetics of Vesico-Ureteric Reflux and CAKUT Disorders 2:10-2:30 Nina Knoers CAKUT 2:30-2:50 Paola Romagnani The good and bad of kidney repair 2:50-3:10 Kai Schmitt-Ott Grainyhead/CP2 transcription factors in renal development, homeostasis and disease 3:10-3:30 Simone Sanna Cherchi 3:30-4:00 Break 4:00-6:00 Session VII: Renal Injury, Regeneration, New Technologies Moderator: J. Bonventre 4:00-4:20 Tomer Kalisky Cellular heterogeneity in kidney development and tumorigenesis 4:20-4:40 Steven Potter Single cell studies of kidney development 4:40-5:00 Peter Hohenstein <Title Pending > 5:00-5:20 Iain Drummond Stem cell-based kidney regeneration 5:20-5:40 Ben Humphreys Cellular Diversity of Human Kidney and Kidney Organoids Defined by Single-Cell RNA-Seq 6:00-7:00 Dinner END OF IWDN PROGRAM International Workshop on Developmental Nephrology Agenda Page 8