IBUS SEMINAR MARCH 9-10, 2018 TECHNOPARK Zürich. Emphasis on high risk lesions with consensus conference PRELIMINARY PROGRAM

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IBUS SEMINAR 2018 Emphasis on high risk lesions with consensus conference MARCH 9-10, 2018 TECHNOPARK Zürich PRELIMINARY PROGRAM A seminar held under the patronage of the Secretariat Office meeting com Congress Organisation info@meeting-com.ch T 021 312 92 61 Scientific board Florian Dammann, Bern / Zürich, Switzerland Rahel Kubik, Baden, Switzerland Alexander Mundiger, Osnabrück, Germany Christoph Rageth, Geneva, Switzerland Christoph Tausch, Zürich, Switzerland, Switzerland Online registration www.meeting-com.ch / Conferences & Meetings / 2018

Welcome Dear Colleagues, In the name of the organizing committee and the IBUS faculty members, we wish you a very warm welcome to Zürich, and to this IBUS : Advanced Breast Ultrasound course. This program will again demonstrate the top standards in comprehensive breast diagnosis and is designed to circulate actual information concerning the whole scope of breast imaging. It is directed to sonographers (radiologists, gynecologists and surgeons) who accept the importance of having a conclusive diagnosis before any open surgery. You will find yourself in the middle of a rejuvenated area of the city with many new facilities such as cinemas, restaurants, hotels and also a number of shops. The Hardbrücke is the next town trains stop approximately 800 meters from the meeting venue, and from there you can reach downtown by train within a few minutes. KliniK Hirslanden COMMiTTed TO THe HiGHesT standards Klinik Hirslanden is one of Switzerland s leading private hospitals and is part of the Hirslanden Private Hospital Group. Our patient-oriented approach and cutting-edge medicine informed by the latest research shape our day-to-day activities. Hirslanden s interdisciplinary network of experienced medical specialists and the knowledge of our specialised centres of expertise ensure patients receive integrated and comprehensive medical care. Patients can expect professional and personalised assistance provided by our qualified nursing staff. Exceptional comfort, privacy and hotel-style service round off the Hirslanden experience. For more information, please visit www.klinikhirslanden.ch After having already met in Zürich for eight IBUS programs in the Technopark and the facilities of the University Hospital of Zürich, we decided again for the Technopark, where teaching, learning and friendship could be best brought together under the one roof. This part of the Technopark was built 25 years ago, and since 1993 hundreds of motivated, future-oriented people have been working within the Technopark site in different fields which include industrial, commercial and service enterprises and also in industry-oriented research teams. The main goal will be to have again a consensus meeting and consensus statements regarding B3 lesions this will (after 2016) be the second official international consensus conference on B3 lesions. We wish you an enjoyable stay in Zürich, and hope that you will benefit from the expert faculty which has come to share their knowledge with you. We thank all the faculty members, sponsors, the European School of Oncology (ESO) and the Swiss Society of Senology who all support this IBUS meeting. Christoph Rageth (Chairman) Local Organizing Committee EXPERTISE YOU CAN TRUST. 3

Organisation & Speakers Friday, March 9, 2018, 09.00-12.55 & 13.50-18.20 1st day of IBUS 2018 Seminar Saturday, March 10, 2018, 09.00-13.05 & 14.00-16.00 2nd day of IBUS 2018 Seminar Venue Technopark Zürich, Technoparkstrasse 1, 8005 Zürich info@technopark.ch www.technopark.ch Main speakers Elizabeth A. Morris, MD, FACR, Memorial Sloan Kettering Cancer Center, New York (US) Elizabeth A. M. O Flynn, MBBS, MRCS, FRCR, Consultant Radiologist, St. George s Hospital, London (GB) Scientific board Florian Dammann, Bern / Zürich Rahel Kubik, Baden Alexander Mundiger, Osnabrück (DE) Christoph Rageth, Geneva Christoph Tausch, Zürich Invited speakers Andreas Boss, Zürich Sophie Dellas, Basel Michael Knauer, St. Gallen Claudia Kurtz, Lucerne Caroline Malhaire, Paris (FR) Martin Sonnenschein, Bern Seminar language English General information Congress office meeting com Congress Organisation Rue des Pâquis 1 1033 Cheseaux-sur-Lausanne T + 41 (0)21 312 92 61 F +41 (0)21 312 92 63 E info@meeting-com.ch Online registration www.meeting-com.ch / Conferences & Meetings Registration fees Until 18.02.18 From 19.02.18 early bird & onsite 2 Days 9 & 10.3.18 CHF 600.00 CHF 850.00 9 & 10.3.18 SSS members CHF 450.00 CHF 700.00 9 & 10.3.18 residents* CHF 400.00 CHF 520.00 1 Day 9.3.18 CHF 400.00 CHF 500.00 10.3.18 CHF 400.00 CHF 500.00 Residents 9.3.18 CHF 270.00 CHF 350.00 10.3.18 CHF 270.00 CHF 350.00 * In order to benefit from the reduced fee for residents, you are required to send a document of your employer to the Seminar Secretariat by fax (+41 21 312 9263) or scanned (inscriptions@meeting-com.ch) within 7 days from the date of application. The registration fee includes : access to the scientific sessions, certificate of participation, coffee-breaks and lunches. Payment / Confirmation Upon registration you will receive a written confirmation together with the banking details for the payment. Cancellation In case of cancellation 30 days prior the event, the refund of the amount paid will be done net of CHF 60.00 for administrative costs. Thereafter, no refund possible. Any registration made within the early bird time must be paid during this period. It not the case, the invoice is automatically updated at the current price. Administrative costs will be charged to no shows. Legal jurisdiction is Lausanne. Accreditation In demand to the following societies : Swiss Society for Gynaecology and Obstetrics Swiss Society of Radiology Swiss Society of Pathology Swiss Society of Surgery 4 5

Friday March 9, 2018 Friday March 9, 2018 IBUS 2018 Emphasis on high risk lesions with consensus conference 08.50-09.00 Welcome Scientific Board 09.00-09.15 New developments in ultrasound imaging Andreas Boss, Zürich 09.15-09.30 The new BI-RADS : what has changed & why Elizabeth A. Morris, New York (US) 09.30-09.45 Imaging of recurrence (all modalities) Florian Dammann, Bern / Zürich 09.45-09.55 Detection of lymphnodes Martin Sonnenschein, Bern 09.55-10.10 Needle biopsy of lymphnodes when (after the Z0011 trial) and how Michael Knauer, St. Gallen 10.10-10.25 How to manage the axilla initially N+ and clinically negative after neoadjuvant chemotherapy - the radiologists view Sophie Dellas, Basel 10.25-10.40 How to manage the axilla initially N+ and clinically negative after neoadjuvant chemotherapy - the surgeons view Christoph Tausch, Zürich 10.40-10.50 Discussion 10.50-11.15 Coffee break 11.15-11.30 Breast density : assessment and clinical implications Elizabeth A. M. O Flynn, London (GB) 11.30-11.45 The dense breast : how to image Elizabeth A. Morris, New York (US) 11.45-11.50 Comments on dense breast imaging Andreas Boss, Zürich 11.50-11.55 Comments on dense breast imaging Martin Sonnenschein, Bern 11.55-12.10 Intraoperative ultrasound and integration of ultrasound into surgical practice Michael Knauer, St. Gallen 12.10-12.15 Comments on intraoperative ultrasound Christoph Tausch, Zürich 12.15-12.20 Comments on CEM Elizabeth A. Morris, New York (US) 12.20-12.35 Tomosynthesis : ethical not to perform? Elizabeth A. Morris, New York (US) 12.35-12.45 Tomosynthesis new technical considerations Claudia Kurtz, Lucerne 12.45-12.55 Discussion 12.55-13.50 Lunch break 13.50-14.05 New developments in MR imaging 14.05-14.20 Non mass like enhancement in MRI Rahel Kubik, Baden 14.20-14.25 Comments on non mass like enhancement in MRI 14.25-14.40 Second look Ultrasound after suspicious MR Sophie Dellas, Basel 14.40-14.45 Comments on second look Ultrasound after suspicious MR 14.45-14.55 Discussion 6 7

Friday March 9, 2018 Saturday March 10, 2018 14.55-15.10 DCIS imaging Claudia Kurtz, Lucerne 15.10-15.25 Ultrasound imaging of DCIS - update of new insights Alexander Mundinger, Osnabrück (DE) 15.25-15.35 DCIS pathology (pathological aspects of margins and size) 15.35-15.45 BI-RADS 3 - scourge of screening? Elizabeth A. Morris, New York (US) 15.45-16.00 Review on pathological estimation of size and margins of DCIS in surgical specimens Elizabeth A. Morris, New York (US) 16.00-16.15 DCIS surgery (margins, surgery vs. observation) Michael Knauer, St. Gallen 16.15-16.30 High incidence of DCIS in screening - high risk of overdiagnosis? 16.30-16.40 Discussion 16.40-16.55 Evolution of benign breast lesions under neoadjuvant chemotherapy for breast cancer and the difficulty to manage multiple breast additional lesions at MR staging of breast cancer before NAC Caroline Malhaire, Paris (FR) 16.55-17.05 Can MRI predict reponsiveness of breast cancer to neoadjuvant therapy? 17.05-17.25 Coffee break 17.25-17.40 MRI as a problem solving tool a critical assessment of the evidence 17.40-17.55 Multimodal ultrasound - where do we stand? Alexander Mundinger, Osnabrück (DE) 17.55-18.10 Addition of ultrasound to mammographic screening Florian Dammann, Bern / Zürich 18.10-18.20 Elastography Claudia Kurtz, Lucerne IBUS 2018 Emphasis on high risk lesions with consensus conference 09.00-09.15 Does ABUS have a role in preoperative staging? Alexander Mundinger, Osnabrück (DE) 09.15-09.30 New clinical decision rules to avoid MRI-guided biopsies 09.30-09.45 Indications of preoperative MRI : what are the best Elizabeth A. M. O Flynn, London (GB) 09.45-10.00 Advanced functional MRI techniques Elizabeth A. M. O Flynn, London (GB) 10.00-10.05 Discussion 10.05-10.20 Deep learning : artificial intelligence for mammography assessment Andreas Boss, Zürich 10.20-10.30 Breast implant associated anaplastic large cell lymphoma Caroline Malhaire, Paris (FR) 10.30-10.45 Can we avoid surgery after neoadjuvant chemotherapy? Christoph Tausch, Zürich 10.45-10.50 Discussion 10.50-11.10 MIBB database (VAB s in Switzerland) update Christoph Rageth, Geneva 11.10-11.25 Risk lesions in minimally invasive biopsies: same pathological results different management Martin Sonnenschein, Bern 11.25-11.55 Coffee break 11.55-12.15 Introduction to the voting system and introductory questions Christoph Rageth, Geneva 12.15-12.30 Wrap up of the newest literature in lobular neoplasia 12.30-12.40 Consensus finding 12.40-12.55 Wrap up of the newest literature in flat epithelial atypia 12.55-13.05 Consensus finding 13.05-14.00 Lunch break 8 9

Saturday March 10, 2018 Kind thanks to our sponsors 14.00-14.15 Wrap up of the newest literature in Phyllodes tumors 14.15-14.25 Consensus finding 14.25-14.40 Wrap up of the newest literature in papillomas 14.40-14.50 Consensus finding 14.50-15.05 Wrap up of the newest literature in radial scars 15.05-15.15 Consensus finding 15.15-15.30 Wrap up of the newest literature in atypical ductal hyperplasia 15.30-15.45 250 cases of ADH in CNB and VAB - experience of the Zurich breast center Christoph Rageth, Geneva 15.45-15.50 Discussion 15.50-16.00 Consensus finding 16.00 Take home message & Farewell Scientific Board 16.15 END OF IBUS SEMINAR 2018 & handout of certificates of attendance 10 11

Registration form IBUS SEMINAR 2018 To be faxed or mailed back to meeting.com Sàrl Rue des Pâquis 1 1033 Cheseaux-sur-Lausanne Fax +41 (0) 21 312 92 63 Tel. +41 (0)21 312 92 61 E-mail info@meeting-com.ch Registration and payment online through www.meeting-com.ch Title (Prof., Dr, Mrs, Mr ) Family name First name Institution Street / Adresse Postal Code City Country Email @ Registration fees Until 18.02.18 From 19.02.18 early bird & onsite 2 Days 9 & 10.3.18 CHF 600.00 CHF 850.00 9 & 10.3.18 SSS members CHF 450.00 CHF 700.00 9 & 10.3.18 residents* CHF 400.00 CHF 520.00 1 Day 9.3.18 CHF 400.00 CHF 500.00 10.3.18 CHF 400.00 CHF 500.00 Residents 9.3.18 CHF 270.00 CHF 350.00 10.3.18 CHF 270.00 CHF 350.00 * In order to benefit from the reduced fee for residents, you are required to send a document of your employer to the Seminar Secretariat by fax (+41 21 312 9263) or scanned (inscriptions@meeting-com.ch) within 7 days from the date of application. The registration fee includes : access to the scientific sessions, certificate of participation, coffee-breaks and lunches. Seminar Language English Payment / Confirmation Upon registration you will receive a written confirmation together with the banking details for the payment. Cancellation In case of cancellation 30 days prior the event, the refund of the amount paid will be done net of CHF 60.00 for administrative costs. Thereafter, no refund possible. Any registration made within the «early bird» time must be paid during this period. It not the case, the invoice is automatically updated at the current price. Administrative costs will be charged to no shows. Legal jurisdiction is Lausanne. 12