Residual Cancer. May 3-5, International Symposium. on Minimal. Le Corum. > Preliminary. Program MONTPELLIER, FRANCE

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International Symposium th on Minimal Residual Cancer > Preliminary Program May 3-5, 2018 Le Corum MONTPELLIER, FRANCE Organizers: www.ismrc2018.com

> Committee & Speakers > Welcome to Montpellier Scientific Committee Jean-Yves Pierga (Paris, France) Nick Stoecklein (Düsseldorf, Germany) Confirmed Speakers Emmanuel Antonarakis (Baltimore, USA) Carlos Caldas (Cambridge, UK) George Calin (Houston, USA) Ann Chambers (London, Canada) Lewis Chodosh (Philadelphia, USA) Michael Clarke (Stanford, USA) Lisa Coussens (Portland, USA) Luis Diaz (Baltimore, USA) Caroline Dive (Manchester, UK) Hugh Fan (Gainsville, USA) Françoise Farace (Paris, France) Jérôme Galon (Paris, France) Renaud Garrel (Montpellier, France) Paola Gazzaniga (Roma, Italy) Christine Gilles (Lièges, Belgium) Daniel Hayes (Michigan, USA) Paul Hofman (Nice, France) Dave Hoon (Santa Monica, USA) Wolfgang Jani (Ulm, Germany) Stefanie Jeffrey (Stanford, USA) Raghu Kalluri (Houston, USA) Yibin Kang (Princetown, USA) Dennis Lo (Hong-Kong, China) David Lyden (New-York, USA) Dario Marchetti (Houston, USA) Joan Massagué (New-York, USA) Thibaut Mazard (Montpellier, France) Jean-Yves Pierga (Paris, France) Alain Puisieux (Lyon, France) Howard Scher (New-York, USA) Jonathan Sleeman (Heidelberg, Germany) Nick Stoecklein (Duesseldorf, Germany) Leon Terstappen (Twente, The Netherlands) Jean Paul Thiery (Paris, France) Rik Thompson (Brisbane, Australia) Robert Weinberg (Boston, USA) Tom Würdinger (Amsterdam, The Netherlands) Bruce Zetter (Boston, USA) Dear Colleagues and Friends, Catherine Alix-Panabières Klaus Pantel We warmly welcome you to the 11 th International Symposium on Minimal Residual Cancer in Montpellier in the south of France. These international ISMRC meetings started in 1996 and have established themselves, every other year, as a premier event focusing on Minimal Residual Cancer in patients with solid tumors. The MONTPELLIER ISMRC meeting is a great opportunity to gather during three days, researchers from academia and industry to share information about the most recent technical developments, clinical trials and late breaking news. The 2018 meeting in Montpellier is organized together with the established EU-IMI consortium CANCER-ID and brings together basic and clinical researchers from academia and companies. The MONTPELLIER-ISMRC 2018 program will focus on LIQUID BIOPSY in a broader sense and will include presentations on Circulating Tumor Cells (CTCs) as well as circulating nucleic acids (DNA, mirna) and exosomes, with emphasis on clinical studies as well as the biology of metastasis, including cancer stemness, dormancy, epithelial-mesenchymal transition and immunomodulation of tumor cells. Besides invited plenary talks by leading international experts, the MONTPELLIER-ISMRC 2018 includes oral communications and poster presentations selected from the submitted abstracts to support young investigators as well as a session for companies developing new technologies for liquid biopsy. We invite you to submit your abstract for consideration by our Advisory Committee for presentation at the MONTPELLIER-ISMRC 2018 meeting. After great cities like Munich, Berlin, Oslo, San Francisco, Hamburg, Athens, Osaka & Paris, the next ISMRC will take place May 3-5, 2018 at the Corum in Montpellier, France. We hope that you will enjoy your time attending this 11th ISMRC meeting in MONTPELLIER and enjoy the opportunity to exchange information and establish long lasting collaborations with your colleagues. We will be very happy to welcome you in May 2018 in Montpellier! 2018 INTERNATIONAL SYMPOSIUM ON MINIMAL RESIDUAL CANCER BI DETECT

> Preliminary Program & Sessions May 3, 2018 > Preliminary Program & Sessions May 4, 2018 8h30 9h00 09h30 10h00 10h25 11h20 11h45 12h10 13h45 14h10 17h30 Welcome Remarks Catherine Alix-Panabières Klaus Pantel Next Generation Liquid Biopsies Keynote lecture SESSION 1 Cancer Cell Stemness and Epithelial-Mesenchymal Plasticity Bob Weinberg (Boston, USA) - Keynote lecture Jean Paul Thiery (Paris, France) Rik Thompson (Brisbane, Australia) Michael Clarke (Stanford, USA) Christine Gilles (Liege, Belgium) Alain Puisieux (Lyon, France) 10h50 - Coffee Break 12h35 - Lunch Break and e-poster Session SESSION 2 Immune System and Cancer Lisa Coussens (Portland, USA) Paola Gazzaniga (Roma, Italy) 15h05 - Coffee Break SESSION 3 Selected Oral Presentations Refreshments in the Exhibition Area and e-poster SESSION 08h30 09h00 09h25 09h50 10h45 11h10 11h35 12h00 12h25 14h00 14h25 14h50 15h15 16h15 16h45 17h10 17h35 18h00 SESSION 4 Biology of Tumor Cell Dissemination and Metastasis Joan Massagué - Keynote lecture Yibin Kang (Princeton, USA) Bruce Zetter (Harvard, USA) Ann Chambers (London, Canada) 10h15 - Coffee Break Lewis Chodoch (Philadelphia, USA) Jonathan Sleeman (Heidelberg, Germany) SESSION 5 Circulating Tumor cells Dario Marchetti (Houston, USA) 12h50 - Lunch Break and e-poster Session Nick Stoecklein (Düsseldorf, Germany) Hugh Fan (Gainsville, USA) Leon Terstappen (Twente, The Netherlands) Stefanie Jeffrey (Stanford, USA) 15h45 - Coffee Break SESSION 6 Circulating Cell-Free Tumor DNA Dennis Lo (Hong-Kong, China) - Keynote lecture Luis Diaz (Baltimore, USA) Carlos Caldas (Cambridge, UK) Dave Hoon (Santa Monica, USA) GALA DINNER

> Preliminary Program & Sessions May 5, 2018 > Notes SESSION 7 CTCs as liquid biopsy in Clinical Studies 08h30 08h55 09h20 09h45 10h10 11h00 11h25 11h50 12h15 12h40 Howard Scher (New-York, USA) - Prostate Cancer Emmanuel Antonarakis (Baltimore, USA) - Prostate Cancer Jean-Yves Pierga (Paris, France) - Breast Cancer Wolfgang Janni (Ulm, Germany) - Breast Cancer Dan Hayes (Michigan, USA) - Breast Cancer Keynote lecture 10h40 - Coffee Break Françoise Farace (Paris, France) - Lung Cancer Paul Hofman (Nice, France) - Lung Cancer Caroline Dive (Manchester, UK) - Lung Cancer Renaud Garrel (Montpellier, France) - Head & Neck Cancer Thibault Mazard (Montpellier, France) - Colon Cancer 13h05 - Lunch Break SESSION 2 (II/II) Immune System and Cancer 14h15 Jérôme Galon (Paris, France) 14h40 15h05 15h30 15h55 18h00 SESSION 8 Exosomes, Circulating Cell-Free mirna, Platelets Georges Calin (Houston, USA) David Lyden (New-York, USA) Raghu Kalluri (Houston, USA) Tom Würdinger (Amsterdam, The Netherlands) 16h20 - Coffee Break SESSION 9 Emerging Commercial Technologies Closing Remarks with Poster Awards

> ORGANISATION 44 bd. Périer - 13008 Marseille Phone : +33 (0)4 91 94 54 72 contact@ismrc2018.com