PREVENTIVE CARE RECOMMENDATIONS Detailed descriptions

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PREVENTIVE CARE RECOMMENDATIONS Detailed descriptions How often and what kind of preventive care services you need depends upon your age, gender, health and family history. Not all items on this list are covered benefits for all products or groups with Blue Cross or Blue Plus. Coverage for certain items and services may only be provided for plan and policy years after a certain date. Pharmacy coverage may differ for members with pharmacy benefit managers other than Prime Therapeutics. This list may not represent all possible tests or benefits, and inclusion of a service or item on this list does not guarantee coverage. Check your health plan benefits, or call the number on the back of your member ID card for details on coverage. Additional requirements may apply. Tests ordered during a preventive visit that are not considered preventive care may be subject to deductibles, copays and/or coinsurance. Additionally, treatment or tests for an existing condition or illness are not preventive care and are subject to deductibles, copays and/or coinsurance. CATEGORY GENERAL PREVENTIVE CARE Preventive physical/medical exam age and gender appropriate medical history and physical exam, counseling or anticipatory guidance and risk-factor interventions. May include (not an all-inclusive, or restrictive, list, and additional requirements may apply): Blood pressure screening Skin cancer counseling to reduce ultraviolet (UV) ray exposure Preventive medical exams and counseling Skin exam for melanomas, sores, lesions Aspirin use and counseling for certain people with elevated cardiovascular disease risk o Aspirin for men (45 79) and women (55-79) with a prescription in-network Prostate cancer digital rectal exam Domestic violence screening and counseling Height, weight, body mass index (BMI) CARDIOVASCULAR AND METABOLIC SCREENING TESTS (CERTAIN MEN AND WOMEN) Abdominal aortic aneurysm (AAA) ultrasound Ultrasound screening Cholesterol (lipid) profile Cholesterol, HDL and LDL tests Diabetes screening test Blood glucose and A1C tests Blue Cross and Blue Shield of Minnesota and Blue Plus are nonprofit independent licensees of the Blue Cross and Blue Shield Association. *Prime Therapeutics LLC is an independent company providing pharmacy benefit management services

COUNSELING AND CLINICAL ASSESSMENT OR SCREENING Screening and counseling to reduce alcohol misuse Drug use assessment Alcohol, drug and tobacco misuse Screening and counseling to prevent tobacco use and tobacco-caused disease o Tobacco cessation counseling sessions o FDA-approved tobacco cessation medications, when prescribed and provided innetwork Blood infection Hepatitis B & C virus (HCB and HCV) screening Depression Screening for depression Domestic violence Counseling and screening for interpersonal and domestic violence Behavioral counseling in primary care to promote a healthy diet for adults with hyperlipidemia and other risk factors Nutrition, healthy weight, and physical activity Falls prevention counseling for older adults at increased risk o Vitamin D supplements for men and women 65 and older with a prescription Nutrition counseling Screening and counseling for obesity (specifically, screening for and management of obesity) Sexually transmitted infections (STI), risk reduction counseling and screening Vision and hearing HIV (human immunodeficiency virus) Chlamydia Gonorrhea Syphilis Vision screening glaucoma, acuity, refraction Hearing screening screening test, audiometry and pure tone

IMMUNIZATIONS For details on doses, recommended ages, and recommended populations, see prevention guidelines at healthandwellness.bluecrossmn.com. Listed below are most commonly utilized immunizations list may not be all inclusive Tetanus, diphtheria, pertussis, poliovirus vaccines Influenza vaccines Varicella (chickenpox) vaccines Hepatitis A vaccines Hepatitis B vaccines Human papillomavirus (HPV) vaccines May be offered singly or grouped Measles, mumps, rubella (MMR) vaccines Pneumonia vaccines Meningitis vaccines Zoster (herpes shingles) vaccines Rotavirus vaccines CANCER SCREENING TESTS May include one or more of the following: Stool occult blood (once/year) Air contrast barium enema Sigmoidoscopy/Flexible sigmoidoscopy Proctosigmoidoscopy Colorectal cancer screening Colonoscopy Cancer screening exam, including medically necessary sedation (see Blue Cross medical policy Anesthesia Services for Routine Upper and/or Lower Gastrointestinal Endoscopic Procedures (II-93)) Lung cancer screening Prostate cancer screening Ages 55 to 80 using low dose computed tomography (LDCT). Subject to medical necessity requirements of Blue Cross medical policy Lung Cancer Screening Using Low Dose Computed Tomography (LDCT) (V-08) Prostate specific antigen (PSA) test (once/year) Digital rectal exam (DRE) usually performed as part of preventive medical exam

WOMEN'S HEALTH (ALSO SEE PREGNANCY-RELATED) Preventive physical/medical exam age appropriate medical history and physical exam, Preventive gynecological exam counseling or anticipatory guidance and risk-factor interventions. May include evaluation of: thyroid, breasts and abdomen as well as pelvic exam. Ages 12 to 64. Well-woman visit Contraceptive methods and counseling Counseling for BRCA and BRCA testing Counseling regarding and use of medication to reduce risk of breast cancer Osteoporosis screening Cervical cancer screening Breast cancer screening Ovarian cancer screening May include services such as: Hepatitis B screening Osteoporosis screening Sexually transmitted infection (STI) screening Ages 12 to 64. Counseling for contraception and specific FDA-approved contraceptives, including over-the-counter, when prescribed and provided in-network. Religiously exempt groups and certain plans may exclude this benefit. For women at elevated risk for breast and ovarian cancer, based on medical necessity; may be part of "well-woman visit." BRCA lab tests for women at elevated risk. Eligibility as a preventive benefit subject to medical necessity criteria in Blue Cross medical policy Genetic Testing for Hereditary Breast and/or Ovarian Cancer Syndrome (BRCA1 and BRCA2 Genes) (VI-16) For women at elevated risk; may be part of "well-woman visit" Generic Tamoxifen and raloxifene ages 35 and older with a prescription when provided in-network. Bone density measurement (once/year) Pap test HPV (human papillomavirus) test (women 30 and older) Conventional mammogram, two dimensional (2D), unilateral or bilateral (once/year) CA-125 (once/year) Transvaginal ultrasound (once/year)

PREGNANCY-RELATED Breastfeeding support, supplies and counseling Routine prenatal tests Alcohol, drug and tobacco misuse assessment and counseling, preventive medicine counseling and/or risk factor reduction interventions Sexually transmitted infections (STI), risk reduction and screening Counseling for folic acid supplementation Primary care interventions to promote breastfeeding Breastfeeding support supplies and counseling, including coverage of purchase of a manual breast pump Gestational diabetes mellitus screening Presence of bacteria in the urine Hepatitis B Iron-deficiency anemia Iron supplements for women with a prescription when provided in-network Screening for RH incompatibility Screening and counseling to reduce alcohol misuse Drug use assessment Screening and counseling to prevent tobacco use and tobacco-caused disease o Tobacco counseling during pregnancy o FDA-approved tobacco cessation medications, when prescribed and provided innetwork o Preventive medicine counseling and/or risk factor reduction interventions HIV (human immunodeficiency virus) Chlamydia Gonorrhea Syphilis For women planning pregnancy; may be part of "well-woman visit" Folic acid supplements for women ages 12 64 with a prescription when provided in-network

CHILDREN AND ADOLESCENTS Preventive medical exam for children and adolescents`(bright Futures) Depression screening Nutrition, healthy weight and physical activity Vision and hearing Behavioral health assessment Tooth decay and cavity prevention Tuberculosis testing Preventive physical/medical exam age and gender appropriate medical history and physical exam, counseling or anticipatory guidance and risk-factor interventions. May include the following benefits (not an all-inclusive, or restrictive, list): Blood pressure screening Skin cancer counseling to reduce ultraviolet (UV) ray exposure Skin exam for melanomas, sores, lesions Iron supplementation recommendation for children at increased risk for iron-deficiency anemia o Iron supplements for children ages 6 12 months and women 12 17 with a prescription; Domestic violence screening and counseling Height, weight, body mass index (BMI) Safety and injury prevention Assessment of risk for lead exposure Screening for depression Behavioral counseling in primary care to promote a healthy diet for people with hyperlipidemia and other risk factors Nutrition counseling Screening and counseling for obesity (specifically, screening for and management of obesity) Vision screening glaucoma, acuity, refraction Hearing screening screening test, audiometry and pure tone Includes: Alcoholism/substance abuse Intellectual and mental disorders Depression Behavioral Health Assessment Fluoride supplements for children whose water supply lacks fluoride, ages 6 months to 6 years old with a prescription. Topical application of fluoride varnish birth through 6 years old Testing for tuberculosis (TB) for children