Catherine Fassbender, Ph.D. Fassbender Catherine, Ph.D., Assistant Professional Researcher, Department of Psychiatry and Behavioral Sciences, School of Medicine Education B.A., Psychology, University College Dublin, Ireland, 2000 H.Dip. Statistics, Trinity College Dublin, Ireland, 2002 Ph.D. Psychology, Trinity College Dublin, Ireland, 2005 Biography Dr. Fassbender graduated from the Trinity College Dublin, Department of Psychology and Institute of Neuroscience, graduate program in the field of cognitive neuroscience in 2005. Her graduate work involved investigating cognitive control through the use of functional magnetic resonance imaging (fmri). She subsequently moved to the University of Maryland, Baltimore, Department of Psychiatry, Division of Child and Adolescent Psychiatry, where she examined cognitive control in children and adolescents with ADHD. In 2007 she accepted a position at the UC Davis MIND Institute and Department of Psychiatry where she continued researching cognitive control in ADHD. She has also expanded her research interests to include the examination of cognitive impairments in other clinical disorders such as substance dependence at the UC Davis Imaging Research Center. Dr. Fassbender became a member of the MIND Institute faculty in 2012. Her interests include understanding the neural correlates of cognitive control processes in clinical disorders, examining cognition and reward processing following long-term substance abuse, determining neural risk factors for relapse from sobriety in substance users and examining the neural and behavioral risk factors for substance abuse in adolescents. She conducts her research using behavioral, functional neuroimaging and electrophysiological methods. Dr. Fassbender s goal is to better understand the cognitive impairments in clinical disorders in order to inform targeted treatments. She is also interested in identifying patterns of brain and behavior function that will inform the early identification of individuals vulnerable to substance dependence with the goal of prevention. Publications Fassbender C, Krafft CE, Schweitzer JB. (2015) Differentiating SCT and inattentive symptoms in ADHD using fmri measures of cognitive control. NeuroImage: Clinical, 21(8):390-7
Weissman, D.G., Schriber, R.A., Fassbender, C., Atherton, O., Krafft, C., Robins, R.W., Hastings, P.D. & Guyer, A.E. (2015) Earlier adolescent substance use onset predicts stronger connectivity between reward and cognitive control brain networks. Developmental Cognitive Neuroscience, 16, 121-9 Fassbender, C., Lesh, T.A., Ursu, S. & Salo, R. (2015) Reaction Time Variability and Related Brain Activity in Methamphetamine Psychosis, Biological Psychiatry, 77(5): 465-74 Fassbender C., Houde S, Silver-Balbus S., Ballard K, Kim B.K., Rutledge K.J., Dixon J.F., Iosif A.M., Schweitzer J.B., McClure S.M. (2014) The decimal effect: behavioral and neural bases for a novel influence on intertemporal choice in healthy individuals and in ADHD, Journal of Cognitive Neuroscience, 26(11):2455-68 Fassbender C., Scangos, K., Lesh, T.A. & Carter, C.S. (2014) RT distributional analysis of cognitive-control-related brain activity in first-episode schizophrenia. Cognitive Affective and Behavioral Neuroscience, 14(1): 175-88. Mazaheri A, Fassbender C, Coffey-Corina S, Hartanto TA, Schweitzer JB, Mangun GR (2014) Differential Oscillatory Electroencephalogram Between Attention-Deficit/Hyperactivity Disorder Subtypes and Typically Developing Adolescents. Biological Psychiatry, 76(5):422-9 Salo R, Fassbender C, Buonocore MH, Ursu S. (2013) Behavioral regulation in methamphetamine abusers: an fmri study. Psychiatry Research, 30;211(3):234-8 Salo R, Fassbender C, Iosif AM, Ursu S, Leamon MH, Carter C. (2013) Predictors of methamphetamine psychosis: history of ADHD-relevant childhood behaviors and drug exposure. Psychiatry Research, 210(2): 529-35 Green CT, Long DL, Green D, Iosif AM, Dixon JF, Miller MR, Fassbender C, Schweitzer JB. (2012) Will working memory training generalize to improve offtask behavior in children with attention-deficit/hyperactivity disorder? Neurotherapeutics, 9(3):639-48 Fassbender C., Schweitzer, J.B. Cortes, C.R., Tagamets, M.A., Windsor, T.A., Revves, G.M. & Gullapalli, R. (2011) Working memory in attention deficit/hyperactivity disorder is characterized by a lack of specialization of brain function. PLos One, 6(11):e27240
Salo R, Ravizza S, Fassbender C. (2011) Overlapping cognitive patterns in schizophrenia and methamphetamine dependence. Cogn Behav Neurol, 24(4):187-93 Salo R, Gabay S, Fassbender C, Henik A. (2011) Distributed attentional deficits in chronic methamphetamine abusers: evidence from the Attentional Network Task (ANT). Brain and Cognition, 77(3): 446-52 Miller M., Hanford, R.B., Fassbender, C., Duke, M. & Schweitzer, J.B. (2011). Affect recognition in adults with Attention-Deficit/Hyperactivity Disorder, Journal of Attention Disorders 15(6): 452-60 Fassbender, C., Zhang, H., Buzy, W.M., Cortes, C., Mizuiri, D., Beckett, L. and Schweitzer, J.B. (2009). A lack of default network suppression is linked to increased distractibility in ADHD, Brain Research, 1273:114-28 Fassbender, C., Hester, R., Murphy, K., Foxe, J. J., Foxe, D. M. and Garavan, H. (2008). Prefrontal and midline interactions in behavioural control, European Journal of Neuroscience, 29(1): 181-187. Fassbender, C., Simoes-Franklin, C., Murphy, K., Hester, R., Meaney, J., Robertson, I. H. and Garavan, H. (2006). The role of a right fronto-parietal network in cognitive control: Common activations for cues-to-attend and response inhibition, Journal of Psychophysiology, 20(4): 286-296. Fassbender, C., Foxe, J. J. & Garavan H. (2006). Mapping the functional anatomy of task preparation: priming task- appropriate brain networks. Human Brain Mapping,27(10), 819-827. Fassbender, C and Schweitzer, J.B. (2006). Is There Evidence for Neural Compensation in Attention Deficit Hyperactivity Disorder? A Review of the Functional Neuroimaging Literature. Clinical Psychology Review, 26(4), 445-465. Garavan, H., Hester, R., Murphy, K., Fassbender, C. & Kelly, C. (2006). Individual differences in the neuroanatomy of inhibitory control. Brain Research, 1105, 130-142. Fassbender, C., Murphy, K., Foxe, J., Wylie, G., Javitt, D.C., Robertson, I.H. & Garavan, H. (2004). A topography of executive functions and their interactions revealed by functional Magnetic Resonance Imaging. Cognitive Brain Research, 20, 132-143.
Hester, R., Fassbender, C. & Garavan, H. (2004). Individual differences in error processing: A review and Reanalysis of three event-related fmri studies using the GO/NOGO task. Cerebral Cortex, 14, 986-994. Presentations Will Computerized Working Memory Training Generalize to Improve Off-Task Behavior in ADHD? Cogmed Network Annual Conference, Chicago, IL, September 2010 Executive Functioning in ADHD. U.C. Davis M.I.N.D. Summer Institute on Neurodevelopmental Disorders, California State University, Sacramento, CA, August 2007. Mixed Block and Event-related fmri Investigation of Response Inhibition in the Sustained Attention to Response Test (SART). 33 rd Annual Conference of the Psychological Society of Ireland, Waterford 14 17 November, 2002. Research Funding Active: Cognitive and Reward processes in risk for relapse in poly substance dependence NIH/NIDA, 04/01/2015 03/31-2017 Charting the Gateway Years: Linking Brain Connectivity Trajectories and Psychosocial Risk Profiles with Substance Use from Early Adolescence into Young Adulthood UC Davis Behavior Center for Excellence Award, 6/01/2015-5/31/2016 Developmental Changes in Neural Processes Underlying Impulsivity and ADHD (Schweitzer, J), NIH/NIMH, 8/15/2012 8/31/2016 (no cost extension to 5/17) Building Resistance to Distraction via Virtual Reality Therapy Joe P. Tupin Research Award, UC Davis Dept. Psychiatry, 07/01/16-06/30/17 Completed: Identifying Cognitive and Neural Risk Factors for Substance Dependence in ADHD NIH/NIDA, 2/1/2012-1/31/2013, (no cost extension until 01/31/2015) Attention Bias in Comorbid ADHD and Stimulant Dependence
Joe P. Tupin Research Award, UC Davis Dept. Psychiatry 7/01/2013-6/30/2014 (no cost extension until 06/30/2015) Community Service Serves on the UC Davis Imaging Research Center MRI Safety Committee Academic Editor for the International Neuropsychiatric Disease Journal Reviewer for the American Journal of Psychiatry, Biological Psychiatry, Archives of General Psychiatry, Human Brain mapping, Brain Research, Clinical Psychology Review, Journal of Addiction Medicine, Psychiatry Research and Brain Imaging and Behavior. Awards and Honors 2001 Government of Ireland Research Scholarship for the Humanities and Social Sciences 2008 Klingenstein Third Generation Foundation Post-doctoral Fellowship in ADHD 2013 Joe P. Tupin Research Award, UC Davis Dept. Psychiatry