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Transcription:

H. Porst Y. Reisman G. Corona (I) N. Cruz (S) B. Cuzin (F) C. Damsted Petersen (DK) J. Dean (GB) G. Garaffa (GB) I. Gruenwald (IL) E. Kirana (G) L. Lowenstein (IL) F. Palumbo (I) H. Porst (D) Y. Reisman (NL) A. Salonia (I) F. Tripodi (I) C. Bettocchi (I) Y. Burke (IL) M. Giuliani (I) M. Maggi (I) M. Spilotros (I) I. Netzer (IL) I. Petruccelli (I) D. Ralph (GB) D. Schultheiss (D) C. Silvaggi (I) C. Simonelli (I) M. Tedeschi (I) A. Vavallo (I) L. Vignozzi (I) N. Weeg (IL)

Preface... 7 1 The history of sexual medicine... 11 Dirk Schultheiss, Sidney Glina... 11 2 Male genital anatomy and physiology... 34 Ilan Gruenwald... 34 3 Anatomy and physiology of female sexual organs... 54 Beatrice Cuzin... 54 4 Sexual response... 91 Ilan Gruenwald... 91 5 Psychology of sexual response... 98 Francesca Tripodi, Cinzia Silvaggi, Chiara Simonelli... 98 6 Sexual orientation... 175 John Dean... 175 7 Sexuality and childhood... 184 Linda Vignozzi, Mario Maggi, Giovanni Corona... 184 8 Sexuality in the elderly population... 219 Giovanni Corona, Mario Maggi... 219 9 Women hypothalamus-pituitary-gonadal axis... 261 Giovanni Corona, Mario Maggi... 261 10 Let s talk about sex: taking a sexual history... 292 Yacov Reisman... 292 11 Psychosexual treatment methods in sexual medicine... 381 Evie Kirana... 381 12 Hypoactive sexual desire (libido) disorder... 401

Giovanni Corona, Mario Maggi... 401 13 Hormonal disorders and male sexual dysfunction... 431 Giovanni Corona, Mario Maggi... 431 14 Hyperactive sexual disorder... 512 Fabrizio Palumbo, Antonio Vavallo... 512 15 Erectile dysfunction (ED)... 537 Hartmut Porst... 537 16 Ejaculatory/orgasmic disorders in men... 663 16a Basic anatomy and physiology of ejaculation, classification of ejaculatory disorders 665 Hartmut Porst, Natalio Cruz... 665 16b Premature ejaculation... 678 Hartmut Porst... 678 16c Ejaculatory and orgasmic disorders other than premature ejaculation... 737 Natalio Cruz, Hartmut Porst... 737 17 Andrological emergencies... 791 17a Injuries to penis and testicles... 793 Natalio Cruz... 793 17b Priapism... 821 Natalio Cruz... 821 18 Peyronie s disease... 843 18a Peyronie s disease, part I: aetiology, epidemiology, clinical evaluation and conservative therapy... 845 Hartmut Porst, Giulio Garaffa, David Ralph... 845 18b Peyronie s disease, part II: surgical management... 888 Giulio Garaffa, Hartmut Porst, David Ralph... 888 19 Other penile disorders... 910 19a Micropenis... 911 Fabrizio Palumbo, Michele Tedeschi... 911 19b Congenital penile curvature and penile torsion... 927 Natalio Cruz... 927 19c Hypospadias... 952 Natalio Cruz... 952

19d Phimosis... 974 Natalio Cruz... 974 20 Prostate diseases and man s sexual health... 910 20a BPH, LUTS and CP/CPPS... 993 Yacov Reisman... 993 20b Sexual dysfunctions in chronic pelvic pain (CPP)... 1025 Yacov Reisman... 1025 20c Prostate cancer and sexual dysfunction... 1042 Yacov Reisman... 1042 21 Contraception and male sexuality... 1065 Beatrice Cuzin... 1065 22 Female sexual arousal disorder (FSAD)... 1077 Evie Kirana... 1077 23 Sexual desire disorders in women... 1095 Evie Kirana... 1095 24 Female orgasmic disorders (FOD)... 1117 Christina Damsted Petersen... 1117 25 Sexual pain disorders... 1129 Christina Damsted Petersen... 1129 26 Female external genitals disorders... 1140 Beatrice Cuzin... 1140 27 Female sexual function in midlife... 1172 Christina Damsted Petersen... 1172 28 Contraceptive methods and sexual function... 1195 Lior Lowenstein, Natalie Weeg... 1196 29 Changes in sexual function in relation to pregnancy and the postpartum... 1211 Yechiel Z. Burke, Natalie Weeg, Lior Lowenstein... 1212 30 Female sexual function and gynecological disorders... 1227 Lior Lowenstein, Itamar Netzer... 1227

31 Gender identity and related disorders... 1253 John Dean... 1253 32 Non-intercourse sexual behaviours, differing sexual preferences and paraphilias.. 1278 John Dean... 1278 33 Sexual addiction: theory, causes and therapy... 1289 Francesca Tripodi, Marta Giuliani, Irene Petruccelli, Chiara Simonelli... 1289 34 Dermatologic disease of the external genitalia... 1333 Fabrizio Palumbo, Michele Tedeschi... 1333 35 Cancer and sexuality... 1356 35a Cancer and sexuality: general considerations... 1357 Yacov Reisman... 1357 35b Iatrogenic sexual dysfunction... 1407 Carlo Bettocchi, Marco Spilotros... 35c Sexual rehabilitation after pelvic surgery... 1431 Yacov Reisman... 1431 36 Basics on sexually transmitted disease/hiv and their effect on sexuality... 1462 Yacov Reisman... 1463 Colophon...

The modern era of Sexual Medicine started in the sixties of last century with the invention of penile implants followed by penile revascularization procedures. Until this date treatment of sexual dysfunctions, and here especially erectile dysfunction, was more or less an exclusive domain of psychiatrists and sex-therapists with psychotherapy and behavioral therapy oriented approaches. The development of intracavernous self-injection therapy in the 80ies last century represented the first effective medical treatment for ED but the real breakthrough in the management of ED was marked 1998 by the advent of effective oral drug-therapy with PDE 5 inhibitors when sildenafil,the first prototype of this compound class, was launched. With this easily available and applicable medication million of men suffering from ED were successfully treated within a short time period.in parallel to the development of new treatment options intensive basic research was conducted in both fields male and female sexual dysfunctions finally contributing to an expanded and detailed knowledge in the physiology and pathophysiology of sexual processes in both sexes. In addition the development and introduction of new diagnostic measures for the evaluation of sexual dysfunctions made at least in men a differentiation between more psychogenic and more organic etiologies much easier. Parallel to these breathtaking developments in Sexual Medicine, which revolutionized the whole field completely, new Sexual Medicine oriented congresses and societies were founded. Starting with the first two International Conferences on Corpus Cavernosum Revascularization organized by Adrian Zorgniotti,a Uro- Andrologist from New York and held 1980 in New York and 1982 Monaco the International Society of Impotence Research (ISIR) was founded from which later on the International Society for Sexual Medicine (ISSM) descended. Later on the respective continental Sexual Medicine Societies developed, in Europe 1995 the European Society for Impotence Research (ESIR) which is now the European Society for Sexual Medicine (ESSM) with more than 1.500 members, currently by far the largest continental society in this field. Besides the annual congresses of ESSM which build yearly the ideal platform for between 1,200 and more than 2,000 participants for extensive exchange of the newest science in the field of Sexual Medicine, the main focus of attention of ESSM was education of young and inexperienced colleagues to prepare them for the routine practice management of patients presenting in their practices and clinics because of sexual dysfunctions. In 2007 the first Oxford school of Sexual Medicine was initiated by the ESSM with yearly 2 weeks of intensive education in Sexual Medicine followed by additional courses. With the 2011 annual congress ESSM implemented for the first time a 3 days ABC Master Course on all aspects of Sexual Medicine. Also in 2011 a Multidisciplinary Joint Committee on Sexual Medicine (MJCSM) under the auspices of the UEMS (Union Européenne des Médecins Spécialistes) was convened on initiative of ESSM to set the administrative and legal basis for an European qualification examination in Sexual Medicine. Members of the MJCSM are European representatives of the European Board of Urology, Gynecology and Obstetrics, and Psychiatry.

In front of you will find the first edition of the syllabus of Sexual Medicine, which was composed by the first educational committee of the European Society for Sexual Medicine (ESSM). The content of the curriculum for Sexual Medicine as identified by the MJCSM does at present not exist in any one or even more textbooks as is meanwhile routine for all other special disciplines in medicine. To specialize for these disciplines and prepare themselves for the exam interested candidates can quite easily identify several standard text books in each discipline and chose this one which meets his expectations. With the new certification for Sexual Medicine the situation is quite different as mentioned above and finally prompted the ESSM to found a new Educational Committee with the intention to take care of all educational and instructional issues related to that subject. The result of this indeed challenging work you have now in hands: The syllabus for sexual medicine, a textbook which covers all the different aspects of Sexual Medicine and of course the contents of the forthcoming exam for the qualification in Sexual Medicine. The authors of this comprehensive syllabus, mainly members of the ESSM Educational Committee, were forced to put the whole content together within a short period of below one year, which everybody knows is a very challenging task to comply with.with these facts in mind it should be clear for everybody that this first syllabus on Sexual Medicine cannot be perfect and may have some minor shortcomings. Nevertheless the reader is assured that the authors provide you with the best possible content manageable in such a short time. Aware of the fact that some minor contents may be missing or are incomplete, this syllabus is intended to become a permanently updated work where the newest and most important developments will be added on a yearly basis in each respective chapter. This syllabus is primarily edited as a CD-ROM and is intended to be afterwards also available in a book form. The CD-ROM will be available without any additional charge for all candidates for the exam. The content of the syllabus is diversified in four sections: I General considerations in Sexual Medicine, including history, anatomy, physiology, endocrinology and psychology as well as sexual development and orientation. II Male sexual disorders and considerations III Female sexual disorders and considerations IV Mixed topics including identity disorders, addiction, paraphilia, cancer and sexuality and sexually transmitted diseases Each chapter addresses a specific disorder, including an introduction to the field, definition and description of the disorder, prevalence and risk factors, assessment strategies, and recommendations for treatment. We are grateful to the authors of this outstanding piece of medical science who sacrificed their free time and contributed with their expertise and intellect to the syllabus. We hope you, the reader, finds this volume informative and useful, both to prepare yourself for the exam and to support you in your daily routine work with the patients in your practice. Moreover, we also would like to thank to all the authors, the members of the ESSM executive committee for their support,woet Gianotten and Johannes Bitzer for their reviewing work and Tracy Hamilton to edit this opus. Hartmut Porst, President of the ESSM Yacov Reisman, Chair of the Educational Committee