BudvaMontenegro 4 th 7 th October rd AROME MONTENEGRO COURSE: BRIDGE BETWEEN SCIENCE AND CLINICS IN ONCOLOGY

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4 th to 7 th October 2017. Budva, Montenegro 3 rd AROME MONTENEGRO COURSE: BRIDGE BETWEEN SCIENCE AND CLINICS IN ONCOLOGY 2 nd AROME ESO JOINT CONSENSUS CONFERENCE: ACCESS TO CANCER CARE INNOVATIONS IN EMERGING COUNTRIES FINAL PROGRAM Conference Presidency: Joseph GLIGOROV AROME President Vladimir TODOROVIC Director of Oncology & radiotherapy clinic, Clinical Center of Montenegro, University of Montenegro Matti AAPRO European School of Oncology (ESO) Sharing Progress in Cancer Care Department coordinator Scientific Committee: J. Gligorov, V. Todorovic, M. Aapro, Y. Belkacemi Organization ASTAKOS Travel Club Jadranski put 16; 85310 Budva Montenegro Tel: +382 33 452 258; Fax: +382 33 452 852; e mail: officebd@astakos.com

4 th October 2017 14:30 14:40 Welcome and Introduction (J. Gligorov, V. Todorovic) 14:40 15:00 Ministry of Health of Montenegro (Minister K. Hrapovic) Faculty of Medicine University of Montenegro allocution (Dean Ac Pr, G. Nikolic) 15:00 15:45 Cancer in emerging countries: challenges for International organizations (J. Gligorov) 15:45 16:15 Coffee break 16:15 18:15 Session 1: Innovations in cancer diagnostics (Chairs: Z. Eri, K. Kerrou) 16:15 16:35 Challenges for oncopathologists in emerging countries (F. Vukmirovic) 16:35 17:00 Models of access to molecular oncology diagnostics in emerging countries (S. Radulovic) 17:00 17:30 Liquid biopsies and CTC: the future of pathology? (F.C. Bidard) 17:30 18:00 PET CT imaging in oncology: the new staging and follow up standard (K. Kerrou) 18:00 18:15 Discussion 18:15 19:30 Session 2: Innovations in cancer locoregional therapies (Chairs: R. Dzodic, N. Vasev) 18:15 18:45 Modern surgical oncology challenges in emerging countries (I. Markovic) 18:45 19:15 Radiotherapy innovations in emerging countries from Africa and Latino America (O. Arsovski) 19:15 19:30 Discussion

5 th October 2017 09:00 10:15 Session 3: Gastro intestinal cancers: innovations, indications and access in emerging countries (Chairs: N. Mijalkovic, A. Khalil) 09:00 09:30 Metastatic CRC in Southwestern Europe Challenges and perspective (N. Mijalkovic) 09:30 10:00 Targeted therapies in other gastro intestinal cancers (A. Khalil) 10:00 10:30 Update on Therapy of Metastatic Colorectal Cancer: Beyond VEGF and EGFR.Discussion (T. Dragovich) 10:30 10:45 Coffee break 10:45 12:30 Session 4: Breast Cancers: innovations, indications and access in emerging countries (Chairs: S. Beslija, G. Mustacchi) 10:45 11:15 New targeted approaches in HER2 positive breast cancers (V. Todorovic) 11:15 11:45 Do we have appropriate targeted treatments for triple negative breast cancers? (I. Durutovic) 11:45 12:15 Optimal endocrine treatment strategies in HR positive breast cancers (Z. Tomasevic) 12:15 12:30 Discussion 12:30 13:30 Educational program sponsored ROCHE Early breast cancer: Expectations for HER2morrow 12:30 12:35 Opening and introduction Prof. dr Joseph Gligorov

12:35 12:55 Starting EARLY Neoadjuvant treatment approach at HER2 positive cancer patients Prof. dr Vladimir Todorović 12:55 13:15 For HER 2morrow rationale for continuous HER2 dual blockade and long term outcome Prof. dr Joseph Gligorov 13:15 13:30 Discussion and conclusion Prof. dr Joseph Gligorov, Prof. dr Vladimir Todorović 13:30 14:30 Lunch break 14:30 16:15 Session 5: Lung cancers: innovations, indications and access in emerging countries (Chairs: N. Secen, Y. Belkacemi) 14:30 15:00 Cancer cells targeted treatments strategies in adenocarcinomas out of immune checkpoints treatments (D. Radosavljevic) 15:00 15:30 Systemic treatments of small cell lung cancers and Mesothelioma (M. Bourhafour) 15:30 16:00 Immuno checkpoints and angiogenesis targeted treatments in lung cancers (T. Ceric) 16:00 16:15 Discussion 16:15 16:45 Coffee break 16:45 17:45 Educational program sponsored PFIZER Reflection on the latest advancements in HR+/HER2 mbc treatment". Prof. dr Eduard Vrdoljak, Split, Croatia, Prim. dr Ljiljana Stamatovic, Belgrade, Serbia 17:45 18:45 Educational program sponsored MERCK Cetuximab standard of care in colorectal and head & neck cancers 17:45 17:50 Introduction Prim. dr Davorin Radosavljević, Serbian Institute of Oncology and Radiology, Belgrade 17:50 18:05 Present and future of RAS testing in mcrc Prof. dr Filip Vukmirović, Clinical Center of Montenegro, Podgorica 18:05 18:20 Cetuximab as 1st line therapy option in mcrc

Prim. dr Davorin Radosavljević, Serbian Institute of Oncology and Radiology, Belgrade 18:20 18:35 Treatment algorithms in head and neck cancers role of cetuximab in LA and R/M disease Ass. dr Borislava Nikolin, Vojvodina Institute of Oncology, S. Kamenica 18:35 18:45 Closing remarks and discussion 18:45 19:45 Educational program sponsored ASTRA ZENECA Ovarian cancer management where are we now and where are we going to? Importance of surgery in ovarian cancer management Prof. dr Aleksandar Stefanovic PARP inhibitors personalised approach in ovarian cancer management Prim. dr Ljiljana Stamatovic 6 th October 2017 09:45 10:45 Session 6: Cutaneous cancers: innovations, indications and access in emerging countries (Chairs: D. Vrbanec, J. Gligorov) 09:45 10:15 Systemic targeted treatments options for malignant melanomas (M. Risteski) 10:15 10:35 Hedgehog pathways inhibition in basal Cell Carcinomas (N. Milasevic) 10:35 10:45 Discussion 10:45 11:15 Coffee break 11:15 13:00 Session 7: Gynecologic Cancers: innovations, indications and access in emerging countries (Chairs: S. Vasovic, O. Arsovski) 11:15 11:45 Targeted treatments in ovarian cancers (L. Stamatovic)

11:45 12:15 New RT approaches and innovations in gynecologic cancers (O. Arsovski) 12:15 12:45 New systemic approaches for high risk and metastatic endometrial and cervical malignancies (S. Vasovic) 12:45 13:00 Discussion 13:00 15:00 Lunch 15:00 16:45 Session 8: Genito urinary cancers: innovations, indications and access in emerging countries (Chairs: E. Vrdoljak, J. Lakicevic) 15:00 15:30 Immuno checkpoint and anti angiogenic approaches in metastatic renal cell cancers (E. Vrdoljak) 15:30 16:00 Optimal hormones and systemic approaches in prostate cancers (V. Kovcin) 16:00 16:30 Immuno checkpoint approaches in urothelial cancers (L. Popovic) 16:30 16:45 Discussion 16:45 17:00 Coffee break 17:00 17:45 Patient advocacy groups meeting 17:45 18:45 AROME Young Oncologists network (D. Tesanovic, I. Durutovic, L. Popovic) 20:30 Gala dinner Venue Banquette Hall Mediteran

7 th October 2017 2nd AROME ESO JOINT CONSENSUS CONFERENCE: ACCESS TO CANCER CARE INNOVATIONS IN EMERGING COUNTRIES PANELISTS: Matti Aapro, Oliver Arsovski, Yazid Belkacemi, Semir Bešlija, Francois Clement Bidard, Mouna Bourhafour, Timur Cerić, Svetlana Corsovic, Tomislav Dragovich, Ivana Durutović, Radan Džodić, Živka Eri, Joseph Gligorov, Vanja Karadjinovic, Khaldoun Kerrou, Ahmed Khalil, Vladimir Kovčin, Jadranka Lakićević, Nevenka Lukovac Janjic, Ivan Marković, Nenad Mijalković, Nikola Milašević, Giorgio Mustacchi, Nicholaos Pavlidis, Lazar Popović, Davorin Radosavljević, Siniša Radulović, Milan Risteski, Nevena Sečen, Snezana Smickovska, Milan Sorat, Ljiljana Stamatović, Igor Stojkovski, Dušanka Tešanović, Vladimir Todorović, Zorica Tomašević, Suzana Vasović, Damir Vrbanec, Eduard Vrdoljak, Filip Vukmirović, 08:45 09:00 Welcome and Introduction (Chairs: J. Gligorov, V. Todorovic. N. Pavlidis) 09:00 09:45 Are Solid Cancers of Unknown Primary a challenge for emerging countries (N. Pavlidis) 09:45 10:00 ESO presidential lecture: Elderly cancer population in emerging countries (M. Aapro) 10:00 11:15 2 nd AROME ESO joint consensus conference: access to cancer care innovations in emerging countries (Part 1) 11:15 11:30 Coffee break 11:30 13:00 2 nd AROME ESO joint consensus conference: access to cancer care innovations in emerging countries (Part 2) 13:00 14:00 Lunch

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