Food Glorious Food Epidemiology of Food and Nutrition- Related Diseases and Conditions

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Food Glorious Food Epidemiology of Food and Nutrition- Related Diseases and Conditions Danielle Greenberg PhD, FACN Director, R&D Nutrition PepsiCo

Conflict of Interest Disclosure I am a full-time employee of PepsiCo. The views and opinions expressed herein are my own and do not necessarily reflect those of PepsiCo. 2

3 Epidemiology of Food and Nutrition- Related Diseases and Conditions Historical perspectives Global trends in nutrition-related diseases Nutrition and health - a reason for hope The need for effective partnerships

Food, Nutrition, and Health Time Period Major Themes Examples & Dates 1700's- 1950's 1950's - Today Tomorrow Severe Deficiency Diseases Non Communicable Diseases and Conditions Health & Wellness Food Security Food Distribution Scurvy (1700-1750) Goiter (1820-1920) Beri-beri (1912) Pellagra (1900-1920) Rickets (1930's) Obesity; Type 2 diabetes Heart disease; Stroke Some cancers Whole Foods Closer-to-whole Foods Functional Foods Processed Foods Balanced Diets 4

5 The Aim of Dietary Guidelines: Then and Now Historically, nutrients were to prevent deficiencies James Lind wrote a Treatise on Scurvy (1747). Where he described his clinical trials that proved that citrus fruits and juices would prevent scurvy. Joseph Goldberger demonstrated in the early 1900"s that pellagra, was caused by a nutritional deficiency and could be cured by the addition of fresh milk, meats, or yeast to the diet.

JAMA 1941;116 (23): 2598-2599 6 In 1941, President Roosevelt pointed out the major nutrition challenge in the U.S. Every survey of nutrition shows that here in the United States, undernourishment is widespread and serious.

Concerns about the total Food Supply and Food Supply Adjusted for Losses Calories per person per day 4,000 3,500 Total food supply available for consumption 1 3,000 2,500 2,000 1910 1920 1930 1940 1950 1960 1970 1980 1990 2000 1 Rounded to the nearest hundred. 2 Not calculated for years before 1970. Food supply adjusted for spoilage, cooking losses, plate waste, and other losses 2 Food supply adjusted for spoilage, cooking losses, and other losses

Between 1983 and 2000, per capita calorie intake in the US increased nearly 20% Calories per person per day 4,000 3,500 Total food supply available for consumption 1 3,000 2,500 2,000 Food supply adjusted for spoilage, cooking losses, plate waste, and other losses 2 1910 1920 1930 1940 1950 1960 1970 1980 1990 2000 1 Rounded to the nearest hundred. 2 Not calculated for years before 1970.

Important Drivers of the Rising Burden of Major Chronic Disease Risk Factors Lifestyle and behavioral changes Decreasing physical activity Nutritional transition Other major health transitions

Cardiovascular epidemic in countries of different stages of development 10

Heart disease, stroke, cancer, diabetes, and other chronic diseases are leading causes of death globally Data from WHO Global Infobase (2004) Accessed March 17, 2010 11

Cardiovascular diseases are the leading cause of death in the world; Data from 2005 20 17.5 Deaths (millions) 15 10 5 0 7.6 4.1 2.8 1.6 0.9 1.1 HIV/AIDS TB Malaria CVD Cancer COPD Diabetes www.who.int/chp/chronic_disease_report/en/ 12

In reality, 80% of these chronic disease deaths occur in low and middle income countries www.who.int/chp/chronic_disease_report/en/ 13

Many of the leading risk factors for death are related to poor nutrition http://www.who.int/healthinfo/global_burden_disease/globalhealthrisks_report_full.pdf 14

UN High Level Meeting on NCDs Sept. 2011 15

The NCD Alliance Mbanya JC et al. Lancet. 2011 Feb 12;377(9765):536-7.

17 The Aim of Dietary Guidelines: Then and Now From the 1950's to the present, the focus has been the prevention and control of NCDs. Dietary guidance now aims to prevent or control: Obesity; Type 2 diabetes Cardiovascular diseases, Stroke Cancers Other NCDs

Global Trend in Type 2 diabetes 1980 2008 From: The Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group, Imperial College UK 18

Age-standardized mean Systolic Blood Pressure in 2008 Men Women Danaei et al. Lancet 2011

Global overweight and obesity 1960 20

Global overweight and obesity 2010 21

Four papers published in the Lancet with important global & regional trends in nutrition-related risk factors

Food Industry Support of the WHO Global Strategy on Diet, Physical Activity & Health

IFBA Progress Report 2011 https://www.ifballiance.org 24

Successful promotion of HEALTH is feasible, however: Governmental coordination and leadership will be required. Actions across multiple sectors of government and society will be necessary. Recognition of major resource constraints is crucial. Efforts across chronic diseases with common risk factors must be integrated. Partnerships with the food industry must be encouraged.

26 What can the food industry do? Promote Health and Wellness through: Balanced diets Whole foods Closer to whole foods Processed foods that are beneficial

Globalization and Health 2010; www.globalizationandhealth.com/content/6/1/10 27

Components of foods for optimal health Foods to encourage Whole and fiber-rich grain foods Vibrantly colored vegetables and potatoes Brightly colored fruits and 100% fruit juices Low-fat and fat-free milk, cheese and yogurt Lean meats, skinless poultry, fish, eggs, beans nuts and seeds Nutrients to encourage Protein, fiber, vitamins A, C and E, calcium, magnesium, iron, potassium 28

Components of foods for optimal health Nutrients to limit: saturated fats trans fats cholesterol salt (sodium) added sugars AND total calories 29

The food industry can address the imbalance between our current and optimal consumption 1 1.Tip the balance of current production in favor of nutrient-dense whole grains. 2 3 4 2.Expand the offerings for delicious, convenient, accessible, and affordable vegetable-based products. 3.Create novel, value-added, low- or reduced-fat dairy products. 4.Deliver fruit-based products that have the full goodness of whole fruit. 30

The Need to Create Partnerships with the Private Sector www.cdc.gov/pcd/issues/2009/apr/08_0236.htm

Developing Trust and Building Effective Public-Private Partnerships Like any other relationship, public-private partnerships must be built on trust. Trust requires a commitment to open and honest dialogue. Common ground and barriers to collaboration must be discussed. Thomas & Curtis. World Bank; 2003.

Conclusions The best time to plant a big tree is twenty years ago. The second best time is now. -- African Proverb Tackling the major issues of food- and nutrition-related diseases and conditions is like planting a big tree we should have started 20 to 50 years ago. However, the second best time to do so is now. 33

THANK YOU!