INTERNATIONAL CONGRESS OF CARDIOLOGY:

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INTERNATIONAL CONGRESS OF CARDIOLOGY: SIC Società Italiana di Cardiologia Organized by the Department of Science for Promoting Health (PROSAMI) Chair and post-graduate School of Cardiovascular Disease School of Medicine, University of President: Prof. Salvatore Novo Director of Division of Cardiology, University Hospital P. Giaccone, Complesso Monumentale Chiaramonte Steri Sala dei Baroni e Sala delle Capriate Palermo (Italy)

Dear Friends and Colleagues, Cardiovascular Disease remain the leading cause of morbidity and mortality in developed and developing countries although tremendous progress has been reached in the last years concerning the prevention, the understanding of pathophysiology, the diagnostic methods, noninvasive and invasive therapy. This International Congress of Cardiology: from Scientific Research to Clinical Practice aim to discuss with an excellent Faculty of national and international scientists from different European countries as well as from USA and Asia, modern aspects in pathophysiology, diagnosis and treatment of different cardiovascular diseases: relevant aspects concerning molecular alterations of troponin in Cardiomyopathies and the progress of high resolution MRI for the diagnosis of this pathology; the continuum from ventricular dysfunction to Heart Failure, the relation with sleep disorders and the new ESC guidelines on Heart Failure. The ESC Guidelines 2016 on Atrial Fibrillation will be discussed analyzing the new pathogenic hypothesis on atrial fibrillation, the pro and contra of cardioversion versus ablation to restore sinus rhythm and the relevant role of new oral anticoagulant in preventing systemic embolism and stroke. The added contribution of strain in echocardiography in different form of cardiopathy (cardiomyopathy, Valvulopathies, dilated cardiomyopathy, arrhythmias) will be discussed. Cardio-oncology is a new branch of cardiology deriving from the close cooperation of cardiologist and oncologist in the study of cardiac and vascular complication of new anticancer drugs in this pathology second only to cardiovascular disease for morbidity and mortality. New drugs to treat cancer often determine a cardiac damage and only the use of biomarkers and imaging technique, in particular global longitudinal strain reduction and cardiac MRI, may consent a precocious diagnosis of heart failure and vascular damage to start a preventive therapy as evidenced in the 2016 Position Paper of the ESC on Cardio-Oncology. Finally will be discussed the relationship between Cardiometabolic risk and Cardio-vascular events also considering the new Guidelines ESC 2016 in Cardiovascular Prevention. We hope that the Congress will consent an interesting change of ideas and an interactive discussion with Italian cardiologists and, of course, we believe that outside from congress works, all participants may enjoy to visit Palermo, one of the Mediterranean town richer in culture and different historical sites. Yours sincerely. Salvatore Novo

FACULTY Agnello Luisa Agricola Eustachio Arrigo Francesco Borghi Claudio Bugiardini Raffaele Calore Chiara Camici Paolo Guido Capucci Alessandro Carerj Scipione Ciaccio Marcello De Caterina Raffaele de Gregorio Cesare Di Biase Matteo Di Lenarda Andrea Elliott Perry Fedele Francesco Fiume Giovanna Galderisi Maurizio Hermann Haugaa Kristina Licata Giuseppe Li Donni Renato Magrì Damiano Manzato Enzo Marino Paolo Mazzola Fabio Mercuro Giuseppe Metra Marco Micari Fabrizio Midiri Massimo Novo Salvatore Novo Giuseppina Oreto Giuseppe Padeletti Luigi Parati Gianfranco Penco Maria Perrone Filardi Pasquale Perticone Francesco Pinto Antonio Pinto Fausto J. Plana Juan Carlos Romeo Francesco Russo Antonio Shlyakhto Evgeny Tocchetti Carlo Gabriele Vitale Francesco Voigt Jens Uwe Zito Concetta Milan, Italy Bologna, Italy Bologna, Italy Padua, Italy Milan, Italy Ancona, Italy Chieti, Italy Foggia, Italy Trieste, Italy London, United Kingdom Rome, Italy Naples, Italy Oslo, Norway Rome, Italy Padua, Italy Novara, Italy Cagliari, Italy Brescia, Italy Milan, Italy Milan, Italy l Aquila, Italy Naples, Italy Catanzaro, Italy Lisboa, Portugal Houston, TX, USA Rome, Italy St. Petersburg, Russia Naples, Italy Leuven, Belgium

Program NO ECM Thursday, January 19 th, 2017 15.00 16.00 Registration of participants 16.00 16.15 Welcome address S. Novo (PALERMO, ITALY) 16.15 17.00 Greetings from the Authorities Pro-Rector F. Mazzola (PALERMO, ITALY) General Manager. University Hospital Paolo Giaccone R. Li Donni (PALERMO, ITALY) Dean of the School of Medicine F. Vitale (PALERMO, ITALY) 17.00 19.15 Opening Lectures CHAIRPERSON: S. Novo (PALERMO, ITALY) The history of Chiaramonte Steri Building G. Fiume (PALERMO, ITALY) LOX-1, oxidant stress, mtdna damage, autophagy, and immune response in atherosclerosis F. Romeo (Rome, Italy) Clinical use of multimodality imaging in the assessment of dilated cardiomyopathy F. J. Pinto (LISBOA, PORTUGAL) 19.30 Welcome cocktail COMPLESSO CHIARAMONTE STERI

Friday, January 20 th, 2017 08.30 10.30 SESSION I New insights in Cardiomyopathies CHAIRPERSONS: A. Di Lenarda (TRIESTE, ITALY), M. Midiri (), P. Marino (Novara, Italy) 10.30 11.30 Lectures 11.30 11.45 Coffee break COMPLESSO CHIARAMONTE STERI Genetic screening in hypertrophic cardiomyopathy patients: clinical implications" C. Calore (Padua, Italy) The diagnostic approach to the infiltrative cardiomyopathies P. Elliott (London, UK) Cardiopulmonary exercise testing in hypertrophic cardiomyopathy D. Magrì (Rome, Italy) High Spatial Resolution Cardiovascular Magnetic Resonance in Patients with Hypertrophic Cardiomyopathy M. Midiri () The system of high education in Italy and the role of the University of Palermo in the 210 anniversary of its foundation F. Micari, RECTOR MAGNIFICUS UNIVERSITY OF PALERMO (ITALY) Translation Research in Cardiology E. Shlyakhto (St. Petersburg, Russia) 11.45 14.00 SESSION II Advances in Heart Failure CHAIRPERSONS: F. Arrigo (), P. Elliott (London, UK), P. Perrone Filardi (Naples, Italy) From Left Ventricular Hypertrophy to Dysfunction and Failure P. G. Camici (Milan, Italy) Diagnostic and prognostic role of galectin-3 in Cardiovascular Disease M. Ciaccio (), L. Agnello ()

13.00 15.00 Light lunch Heart failure and sleep disorders G. Parati (Milan, Italy) The European Guidelines 2016 on Acute and Chronic Heart Failure M. Metra (Brescia, Italy) 15.00 17.00 SESSION III Atrial fibrillation: know how CHAIRPERSONS: M. Di Biase (Foggia, Italy), L. Padeletti (Milan, Italy), A. Pinto () 17.00 17.15 Coffee break Atrial fibrillation with wide QRS complexes: ventricular origin, aberrant conduction or preexcitation? G. Oreto () Oral anticoagulant therapy: when, which? R. De Caterina (Chieti, Italy) Cardioversion or Ablation of atrial fibrillation: state-of-the-art and future perspectives A. Capucci (Ancona, Italy) ESC Guidelines 2016 on Atrial Fibrillation S. Carerj () 17.15 19.15 SESSION IV The added value of strain in echocardiography CHAIRPERSONS: J. U. Voigt (Leuven, Belgium), F. Fedele (Rome, Italy), M. Penco (l Aquila, Italy) 20.00 Dinner Lecture: Inter-vendor variability of strain measurements and the joint efforts of EACVI, ASE and Industry to standardize strain imaging J. U. Voigt (Leuven, Belgium) Cardiomyiopathies C. de Gregorio () Valvulopathies E. Agricola (Milan, Italy) Ventricular arrhythmias K. Hermann Haugaa (Oslo, Norway)

Saturday, January 21 st, 2017 08.30 10.30 SESSION V Diagnosis of cardiac toxicity due to antineoplastic drugs CHAIRPERSONS: G. Mercuro (Cagliari, Italy), J. C. Plana (Houston, Tx, USA), A. Russo () 10.30 10.45 Coffee break Biomarkers G. Novo () Vascular damage C. Zito () Multimodality Imaging approach M. Galderisi (Naples, Italy) European Position Paper on Cardio-Oncology C. G. Tocchetti (Naples, Italy) COMPLESSO CHIARAMONTE STERI 10.45 12.45 SESSION VI Cardiometabolic risk and Cardio-vascular events CHAIRPERSONS: R. Bugiardini (Bologna, Italy), G. Licata (), E. Manzato (Padua, Italy) European Guidelines on Cardiovascular Prevention 2016 S. Novo () Familial hypercholesterolemia: gaining decades of life by optimizing detection and treatment E. Manzato (Padua, Italy) Cardiometabolic Risks, Obesity and Hypertension C. Borghi (Bologna, Italy) Unfavorable inflammatory profile in adults at risk of type 2 diabetes identified by hemoglobin A1c levels according to the American Diabetes Association criteria F. Perticone (Catanzaro, Italy) 12.45 13.00 Closing remarks S. Novo (PALERMO, ITALY) 13.00 14.00 Light lunch

GENERAL INFORMATION Meeting Venue COMPLESSO CHIARAMONTE STERI Secretariat/registration desk during the Meeting The Venue of the Meeting will be Aula Magna dei Baroni The Secretariat/registration desk will be open at the following (2nd Floor) & Aula Capriate (3rd floor). hours: Entrance from Piazza Marina 61- Palermo Thursday, 19th, 2017, from 15.00 to 20.00 Friday, 20th, 2017, from 07.30 to 19.00 C.M.E. CONTINUING MEDICAL EDUCATION Saturday, 21th, 2017, from 07.30 to 13.00 (for Italian Physicians only) Collage S.p.A. (Provider n. 309) has included the Meeting in the Educational Plan 2017. C.M.E ref. :309-177790. Official language The Congress will be suited for Physicians (Cardiologists, Geriatri- The official language of the Meeting will be English cians, General Practitioners, Diabetologists, Internists, Radiologists, Pharmacists) and provides 7 C.M.E. credits Interpretation Service In order to obtain C.M.E. credits, participants must Our Conference interpreters will provide simultaneous interpreta attend the 100% of the Meeting (20 and 21 January) tion services throughout the Congress. fill-in the CME evaluation questionnaire (credits will be granted to Complimentary headphones for simultaneous interpretation will those who will answer 70% correctly) belong to the credited Medical Profession and Specializations related be available upon your arrival at the Meeting venue to this Meeting Submit the required documentation, sign in and sign out at the registration desk at the beginning/end of the Congress C.M.E. Certification The certificate of attendance with the number of C.M.E. assigned credits can be downloaded after 91 days from the date of the Meeting directly through the website www.collage-spa.it/sezione congressi ecm / corsi ecm / select the year and the title of the Event/digit your fiscal code and download your certification Certificate of attendance Certificate of attendance will be issued at the registration desk at the end of the Meeting Technical facilities Facilities will be available for computer presentations and overhead projections. A slide center with PC (Powerpoint for Windows) will be available for check and preview of presentations. It is essential that speakers take their presentation to the slide center at least one hour before the session starts. The slide center will be open at the following hours: Thursday, 19th, 2017, from 15.00 to 20.00 Friday, 20th, 2017, from 07.30 to 19.00 Saturday, 21th, 2017, from 07.30 to 13.00 Lunches and coffee breaks Lunches and coffee breaks will be served in the Meeting area Registrations The Meeting is free to attend Please confirm your participation to the Organizing Secretariat by registering online at www.collage-spa.it within January 16th, Abstracts book 2017. CME registration procedures will continue at the Meeting Participants will receive the Abstract book at the Meeting Venue on January 19th, 2017 Organizing Secretariat and CME Provider Via U. Giordano, 37/A - 90144 Palermo (Italy) - Tel. +39 091 6867.401 - Fax +39 091 9889354 e-mail: giusy.ventura@collage-spa.it - web: www.collage-spa.it