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2015-2016 Influenza Report Week 03 January 17 January 23, 2016 About our flu activity reporting MSDH relies upon selected sentinel health practitioners across the state to report the percentage of total patient visits consistent with an influenza-like illness (ILI: fever of 100 F or higher AND cough and/or sore throat). Also, providers are supplied with specimen collection kits. Samples are submitted to the Mississippi Public Health Laboratory for influenza PCR testing. Reports are used to estimate the state s ILI rate and the magnitude of the state s influenza activity. Reports represent only the distribution of flu in the state, not an actual count of all flu cases statewide. Information is provisional only and may change depending on additional reporting from sentinel providers. State ILI Surveillance During week 03 (01/17/16-01/23/16), the overall state ILI rate (2.8%) was comparable to the previous week (2.5%), but was lower than this time last year (6.3%). Figure 1 Total number of patients treated by sentinel providers in the last three weeks. Table 1 2015-2016 Influenza Season CDC Week Week Ending Total patients ILI symptoms ILI Rate (%) 03 Jan. 23 16076 445 2.8% 02 Jan. 16 19309 491 2.5% 01 Jan. 09 19525 529 2.7%

During week 03, one district (6) had a decrease in ILI activity, while the other eight districts remained about the same. Information is provisional only and may change depending on additional reporting from sentinel providers. Table 2 MSDH District ILI Rates (%) 2015-2016 District Week 02 Week 03 State 2.5 2.8 I 2.7 2.9 II 3.0 2.5 III 5.6 5.9 IV 1.8 1.4 V 1.8 2.1 VI 5.4 4.5 VII 2.1 2.5 VIII 1.4 1.5 IX 3.4 3.7 Overall, the percentage of reported ILI cases has been highest among those in the 0-4 and 5-24 years of age groups. During week 03, however, the percentage was higher among those in the 0-4 years of age group. Figure 2 Page 2 of 12

The 2015-16 state ILI rate was above the national and Region 4 baselines, but was below the state baseline for week 03. Figure 3 Mississippi ILI Rates 2012-2016 Figure 4 Page 3 of 12

Flu Testing Reports 2015-2016 Influenza Season Week 03 Influenza Report Jan. 17 Jan. 23, 2016 During week 03 (week ending January 23 rd ), no laboratory confirmed influenza samples were identified by the MSDH Public Health Laboratory. One confirmed case has been identified during the 2015 2016 season and it was identified as an influenza B. The influenza case was identified from Marshall County. National and Mississippi Pediatric Mortality Surveillance Nationally, no influenza-associated pediatric deaths were reported to CDC during week 03. Seven influenza-associated pediatric deaths have been reported during the 2015-2016 season. Mississippi has had no influenza-associated pediatric deaths reported during this influenza season. For additional information on influenza-associated pediatric deaths, please refer to the CDC s FluView. National ILI Surveillance For week 03, the MS ILI rate (2.8%) was slightly above the national ILI rate (2.2%). Figure 5 US ILI rates from the Centers for Disease Control and Prevention: http://www.cdc.gov/flu/weekly/. Page 4 of 12

During week 03, influenza activity increased slightly in the United States. 1 Figure 6 1 For up-to-date information on flu activity nationwide, please refer to the CDC s website: http://www.cdc.gov/flu/weekly/fluactivitysurv.htm. Mississippi reported Sporadic for the influenza activity during week 03. Table 3 Level of Flu Activity No Activity Sporadic Local Definition Overall clinical activity remains low and there are no lab confirmed cases. Isolated cases of lab confirmed influenza in the state; ILI activity is not increased OR A labconfirmed outbreak in a single institution in the state; ILI activity is not increased. Increased ILI within a single region AND recent (within the past 3 weeks) laboratory evidence of influenza in that region. ILI activity in other regions is not increased OR two of more institutional outbreaks (ILI or lab confirmed) within a single region AND recent (within the past 3 weeks) lab confirmed influenza in that region. Other regions do not have increased ILI and virus activity is no greater than sporadic in those regions Regional Widespread Increased ILI in at least 2 regions but fewer than half of the regions AND recent (within the past 3 weeks) lab confirmed influenza in the affected regions OR Institutional outbreaks (ILI or lab confirmed) in at least 2 regions but fewer than half of the regions AND recent lab confirmed influenza in the affected regions. Increased ILI and/or institutional outbreaks (ILI or lab confirmed) in at least half of the regions AND recent (within the past 3 weeks) lab confirmed influenza in the state. Page 5 of 12

Additional influenza information: Centers for Disease Control and Prevention Centers for Disease Control and Prevention FluView Flu.gov MSDH Flu and Pneumonia World Health Organization FluNet http://cdc.gov/flu/ http://www.cdc.gov/flu/weekly/ http://www.flu.gov/ http://msdh.ms.gov/msdhsite/_static/14,0,199.html http://www.who.int/influenza/gisrs_laboratory/flunet/en/ Page 6 of 12

Appendix Figure 1 Page 7 of 12

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Figure 6 Page 12 of 12