CHAPTER ONE: INTRODUCTION... 1 STUDY GOALS AND OBJECTIVES... 1 REASONS FOR DOING THE STUDY... 1 SCOPE OF REPORT... 1 METHODOLOGY... 1 INTENDED AUDIENCE... 2 INFORMATION SOURCES... 2 ANALYST CREDENTIALS... 2 RELATED BCC REPORTS... 2 BCC ONLINE SERVICES... 3 DISCLAIMER... 3 CHAPTER TWO: SUMMARY... 4 SUMMARY TABLE: GLOBAL CATHETER MARKET, BY REGION, THROUGH 2016 ($ MILLIONS)... 5 SUMMARY FIGURE GLOBAL CATHETER MARKET, BY REGION, 2011 AND 2016 (%)... 5 SUMMARY FIGURE (CONTINUED)... 6 CHAPTER THREE: OVERVIEW OF GLOBAL CATHETER INDUSTRY... 7 CATHETER DEVELOPMENT... 7 CATHETER CONSTRUCTION... 7 CATHETER APPLICATIONS... 8 TYPES OF CATHETERS... 9 CARDIOVASCULAR CATHETERS... 9 Use of Cardiovascular Catheters... 9 Diagnostic Procedures and Cardiac Catheterization... 10 Therapeutic Procedures... 10 TABLE 1 INDICATIONS FOR CARDIAC CATHETERIZATION... 10 TABLE 2 TYPES OF CARDIAC CATHETERS... 11 Angiography Catheters... 11 Angiographic Catheter Features... 11 EP Catheters... 12 Cardiac Ablation Catheters... 12 PCI Catheters... 12 PCI and Stent Placement... 13 TABLE 3 PCI PROCEDURES... 13 Rapid Exchange Balloon Catheters... 14 Over the-wire PCI Catheters... 14 Guiding Catheter... 14 Possible Complications... 14 UROLOGICAL CATHETERS... 15 Development of the Foley Catheter... 15 Type of Urinary Catheterization... 16
Intermittent Catheterization... 16 Possible Complication of Intermittent Catheters... 16 Indwelling Catheterization... 17 Possible Complications from Indwelling Catheters... 17 Suprapubic Catheterization... 17 Possible Complications from Suprapubic Catheterization... 18 Male External Condom Catheterization... 18 Possible Complications From Urinary Catheter Use... 19 NEUROVASCULAR CATHETERS... 19 INTRAVENOUS (IV) CATHETERS... 20 Single-Lumen Catheters... 20 Multi-Lumen Catheter... 21 Specialty IV Catheters... 21 Peripheral Vein Catheter... 21 Central Venous Catheter (CVC)... 21 Tunneling Insertion... 22 Implantation Insertion... 22 Advantages to Central Venous Catheters... 22 Peripherally Inserted Central Catheters (PICCs)... 23 Advantages of PICC Lines... 23 Possible Complications due to IV Catheters... 23 TABLE 4 COMPLICATIONS DUE TO IV CATHETERS... 23 TABLE 4 (CONTINUED)... 24 SPECIALTY CATHETERS... 24 Thermodilution Catheters... 24 Suction Catheters... 25 Oximetry Catheters... 25 END-USER PREFERENCES... 26 SIZE OF CATHETER... 26 MATERIAL USED... 26 COATING... 27 LENGTH OF TIME CATHETER IS IN THE BODY... 27 INFECTION RATE... 27 COST... 28 CHAPTER FOUR: CATHETERS AND WORLD DEMOGRAPHICS... 29 CATHETER-ASSOCIATED INFECTIONS FROM SELECTED PROCEDURES... 29 TABLE 5 GLOBAL TRENDS IN CATHETER-ASSOCIATED INFECTIONS BY ESTIMATED NUMBER OF INFECTIONS PER PROCEDURE TYPE, 2006-2009 (THOUSANDS)... 29 CORONARY PROCEDURES... 29
TABLE 6 SELECTED WORLDWIDE CORONARY PROCEDURES, 2007* (PER 100,000 POPULATIONS)... 30 WORLDWIDE ECONOMIC DEMOGRAPHICS... 30 TABLE 7 HEALTHCARE EXPENDITURE AS A PERCENTAGE OF GDP BY COUNTRY, 2003-2009* (%)... 31 WORLDWIDE POPULATION GROWTH... 32 CHAPTER FIVE: CATHETER MATERIALS... 33 TABLE 8 CHARACTERISTICS OF CATHETER MATERIALS... 33 KEY CHARACTERISTICS... 33 SURFACE CHARACTERISTICS... 34 CATHETER USE IN ADVANCED IMAGING... 34 MRA... 34 OCT... 35 RADIOPACITY IN CATHETERS... 35 Determining Appropriate Properties of Radiopaque Catheters... 36 Economics of Radiopacity... 36 COMPONENT MATERIALS... 37 LATEX... 37 Latex Allergic Reactions... 37 SILICONE... 37 Silicone Catheter Characteristics... 38 Disadvantage of Silicone Catheters... 38 Cost Considerations for Silicone Catheters... 38 POLYTETRAFLUOROETHYLENE (PTFE)... 38 Uses... 39 Cost Considerations... 39 POLYURETHANE (PU)... 39 Uses... 39 Cost Considerations... 40 POLYVINYL CHLORIDE (PVC)... 40 Uses... 40 Cost Considerations... 40 POLYETHYLENE... 40 Uses... 40 Cost Considerations... 40 CATHETER COATINGS... 41 SILICONE ELASTOMER... 41 HYDROPHILIC COATING... 41 ANTIMICROBIAL COATING... 41 Combating UTI... 42 Combining Hydrophilic and Antimicrobial Coatings... 42 Silver Coating... 42
ADVANTAGES AND DISADVANTAGES OF CATHETER MATERIALS... 42 TABLE 9 ADVANTAGES AND DISADVANTAGES OF CATHETER MATERIALS... 43 CHAPTER SIX: ANALYSIS OF THE GLOBAL CATHETER MARKET... 44 FACTORS INFLUENCING MARKET GROWTH... 44 FIGURE 1 FACTORS INFLUENCING THE MEDICAL DEVICE MARKET... 44 DEMOGRAPHIC TRENDS... 45 SURGICAL AND MEDICAL TRENDS... 45 PCI Versus CABG... 45 Combined Therapies... 46 Expansion of Microcatheter Use... 46 CATHETER REUSE... 46 PRODUCT DISTRIBUTION... 46 REIMBURSEMENT AND REGULATION TRENDS... 46 Global Financial Conditions... 47 Third-party Coverage and Reimbursement... 47 Global Cost Containment... 48 LEADING MANUFACTURERS... 48 TABLE 10 TOTAL REVENUES OF KEY CATHETER MANUFACTURERS, 2009 AND 2010 ($ MILLIONS)... 49 MERGERS/ACQUISITIONS IN THE CATHETER MARKET... 49 TABLE 11 MERGERS/ACQUISITIONS IN THE GLOBAL CATHETER MARKET 2007-2011... 50 KEY MARKET DRIVERS... 50 INCREASE IN PROCEDURES HAS LED TO INCREASED DEMAND FOR... 50 CATHETERS... 50 INCREASED DEMAND FOR DISPOSABLE CATHETERS DUE TO RISK OF INFECTION AND TRANSMITTABLE DISEASE... 51 NEW TECHNOLOGIES IN CATHETER DESIGN HAVE INCREASED CATHETER USE... 51 INCREASE IN MINIMALLY INVASIVE PROCEDURES REQUIRING CATHETERS HAS EXPANDED SALES... 51 ADVANCES IN IMAGING TECHNOLOGY HAVE LED TO NEW APPLICATIONS REQUIRING THE USE OF CATHETERS... 52 KEY MARKET RESTRAINTS... 52 PRICE EROSIONS DUE TO FIERCE COMPETITION ARE SHRINKING... 52 REVENUES... 52
LONGER APPROVAL TIMES ARE RESULTING IN DELAYED LAUNCHES OF NEW PRODUCTS... 53 REIMBURSEMENT ISSUES HAVE AFFECTED THE USE OF... 53 TECHNOLOGICALLY ADVANCED CATHETERS... 53 EXPERIENCED PHYSICIANS OFTEN ARE RELUCTANT TO ACCEPT NEW DEVICE TECHNOLOGIES... 53 GLOBAL CATHETER REVENUE ANALYSIS... 53 TABLE 12 PROJECTED GLOBAL CATHETER MARKET BY SEGMENT, THROUGH 2016 ($ MILLIONS)... 54 CARDIOVASCULAR CATHETERS... 54 KEY MARKET CHALLENGES... 55 Pharmacological Approaches Could Threaten Catheter Demand... 55 Lack of Clinical Data Is Hindering Acceptance of Newer Catheters by Physicians and Healthcare Purchasing Organizations... 55 KEY MARKET DRIVERS FOR THE CARDIOVASCULAR SEGMENT... 55 Increases in the Incidence of Cardiovascular Diseases is Driving the Number of Procedures... 55 Popularity of Angioplasty and Stent Placement over Bypass Surgery Is Leading to an Increase in the Use of Cardiac Catheters... 56 Angiography Is Driving the Increase in the Number of Diagnostic Procedures... 56 Interventional Cardiac Procedures Can Be More Effective than Pharmaceutical-based Therapies... 57 KEY MARKET RESTRAINTS IN THE CARDIOVASCULAR MARKET... 57 Constant Price Erosion Is Leading to Decreased Revenues... 57 Decrease in Restenosis is Affecting the Number of Stent Procedures Performed... 57 Catheter Usages Is Restrained due to Low Reimbursement Rates... 58 CATHETER USE IN CONJUNCTION WITH STENT PLACEMENT... 58 Exit of Cordis from Stent Market... 59 CARDIOVASCULAR CATHETER REVENUE ANALYSIS... 59 TABLE 13 PROJECTED GLOBAL MARKET FOR CARDIOVASCULAR CATHETERS BY TYPE, THROUGH 2016 ($ MILLIONS)... 60 Angiography... 60 EP Mapping Catheters... 60 Balloon Catheters... 61 Rapid-exchange Catheters... 61
Guiding Catheters... 61 MARKET SHARES BY COMPANY... 62 FIGURE 2 PROJECTED GLOBAL MARKET SHARE FOR ALL TYPES OF CARDIOVASCULAR CATHETERS, BY COMPANY, 2010 (%)... 63 UROLOGICAL SEGMENT... 63 Market Challenges... 64 Market Drivers... 64 Global Aging of the Population... 64 Catheters with Antimicrobial Coatings Are Increasing Confidence in the Use of Catheter... 64 Urological Catheter Market Revenues... 65 Intermittent Catheter Revenues... 65 Indwelling Catheter Revenues... 65 TABLE 14 PROJECTED GLOBAL MARKET FOR UROLOGICAL CATHETERS, BY TYPE, THROUGH 2016 ($ MILLIONS)... 65 FIGURE 3 PROJECTED GLOBAL MARKET SHARE FOR UROLOGICAL CATHETERS, BY COMPANY, 2010 (%)... 66 INTRAVENOUS... 66 TABLE 15 PROJECTED GLOBAL MARKET FOR INTRAVENOUS CATHETERS BY TYPE, THROUGH 2016 ($ MILLIONS)... 67 FIGURE 4 GLOBAL MARKET SHARE FOR IV CATHETERS, BY COMPANY, 2010 (%)... 68 NEUROVASCULAR SEGMENT... 68 Key Market Challenges... 69 Cost of Neurovascular Catheters... 69 Availability of Pharmacological Treatment Options... 69 Shortage of Qualified Professionals to Perform Surgeries... 69 Key Market Drivers... 70 Enhanced Diagnostic and Imaging Technologies Are Creating New Areas of Treatment... 70 Stenting and Aneurysm Treatments Are Increasing Microcatheter Use... 70 New Catheter Technologies Are Improving Procedures and Increasing Demand... 70 Expanding Market for Unmet Treatment Options... 70 Neurovascular Catheter Market Revenues... 71 TABLE 16 PROJECTED GLOBAL MARKET FOR NEUROVASCULAR CATHETERS, THROUGH 2016 ($ MILLIONS)... 71 Market Share by Company... 72 FIGURE 5 GLOBAL NEUROVASCULAR CATHETER MARKET SHARES BY COMPANY, 2011 (%)... 72 SPECIALTY CATHETER MARKET... 73 Types of Specialty Catheters... 73
Key Market Drivers... 73 Demand for Enhanced Monitoring Devices Is Contributing to Expanded Sales... 73 Effectiveness of Specialty Catheters Is Fueling Growth in Use... 73 Key Market Restraints... 73 Increased Cost of Specialty Catheters Inhibit Sales... 73 Introduction of Competing Technologies... 74 Use of Thrombolytic Drugs... 74 Specialty Catheter Market Revenue Analysis... 74 TABLE 17 PROJECTED GLOBAL SPECIALTY CATHETER MARKET BY TYPE, THROUGH 2016 ($ MILLIONS)... 75 Specialty Catheter Market Analysis... 75 TABLE 18 GLOBAL SPECIALTY CATHETER MARKET SHARES, BY COMPANY AND TYPE OF CATHETER, 2010 (%)... 76 GLOBAL MARKET SHARE FORECAST BY TYPE OF CATHETER... 76 FIGURE 6 PERCENT OF MARKET SHARE BY TYPE OF CATHETER 2011 AND 2016 (%)... 77 FIGURE 6 (CONTINUED)... 78 CONSEQUENCES OF THE ONGOING GLOBAL ECONOMIC RECESSION... 78 PROJECTIONS FOR GLOBAL CATHETER MARKET BY REGION... 78 TABLE 19 PROJECTED GLOBAL CATHETER MARKET BY REGION, THROUGH 2016 ($ MILLIONS)... 79 MARKET REVENUE, BY REGION... 79 Reusable Catheter Use in World Market... 79 GEOGRAPHIC MARKET SHARE BY 2016... 80 EMERGING TECHNOLOGIES... 80 BIOABSORBABLE STENTS... 80 BIFURCATED STENTS... 81 UROVALVE INC.... 81 VOLCANO CORPORATION... 82 CHAPTER SEVEN: THE AMERICAS CATHETER MARKET... 83 GDP AND PERCENT SPENT ON HEALTHCARE IN THE AMERICAS... 83 TABLE 20 GDP AND EXPENDITURE ON HEALTHCARE AS A SHARE OF GDP IN THE AMERICAS, 2009... 83 CATHETER MARKET IN THE AMERICAS... 83 TABLE 21 PROJECTED AMERICAS MARKET FOR CATHETERS BY COUNTRY, THROUGH 2016 ($ MILLIONS)... 84 REVENUE ANALYSIS FOR THE AMERICAS CATHETER MARKET, BY TYPE OF CATHETER... 84 TABLE 22 PROJECTED AMERICAS MARKET FOR CATHETERS BY TYPE, THROUGH 2016 ($ MILLIONS)... 84
THE CANADIAN MARKET... 85 THE MEXICAN MARKET... 85 THE LATIN AMERICAN MARKET... 85 THE SOUTH AMERICAN MARKET... 85 THE U.S. MARKET... 85 U.S. ECONOMIC CONDITIONS... 86 EFFECTS OF HEALTHCARE REFORM IN THE U.S... 86 REIMBURSEMENT... 86 Denial of Reimbursement in U.S.... 87 U.S. REGULATIONS... 87 U.S. Regulations and Reprocessing... 87 CARDIOVASCULAR DISEASE... 88 TABLE 23 U.S. RATES OF CARDIOVASCULAR PROCEDURES, 2007-2009 (THOUSANDS)... 88 TRENDS IN PROCEDURE USAGE... 88 COSTS OF HEART DISEASE IN THE U.S.... 89 REVENUE ANALYSIS FOR CARDIOVASCULAR CATHETERS IN THE AMERICAS... 89 TABLE 24 PROJECTED AMERICAS MARKET FOR CARDIOVASCULAR CATHETERS, THROUGH 2016 ($ MILLIONS)... 89 AMERICAS MARKET TRENDS IN CARDIOVASCULAR CATHETERS... 90 URINARY CATHETERS... 90 TABLE 25 PROJECTED AMERICAS MARKET FOR URINARY CATHETERS, THROUGH 2016 ($ MILLIONS)... 90 AMERICAS MARKET TRENDS IN URINARY CATHETERS... 90 INTRAVENOUS CATHETERS... 91 TABLE 26 PROJECTED AMERICAS MARKET FOR INTRAVENOUS CATHETERS, THROUGH 2016 ($ MILLIONS)... 92 AMERICAS MARKET TRENDS FOR INTRAVENOUS CATHETERS... 92 NEUROVASCULAR... 92 TABLE 27 PROJECTED AMERICAS MARKET FOR NEUROVASCULAR CATHETERS, THROUGH 2016 ($ MILLIONS)... 93 AMERICAS MARKET TRENDS FOR NEUROVASCULAR CATHETERS... 93 SPECIALTY... 93 TABLE 28 PROJECTED AMERICAS MARKET FOR SPECIALTY CATHETERS, THROUGH 2016 ($ MILLIONS)... 94 AMERICAS MARKET TRENDS FOR SPECIALTY CATHETERS... 94 CHAPTER EIGHT: THE EUROPEAN, MIDDLE EAST, RUSSIAN, AND AFRICAN CATHETER MARKET... 95 WESTERN EUROPEAN HEALTHCARE SYSTEMS... 95
EASTERN EUROPEAN AND AFRICAN HEALTHCARE SYSTEMS... 95 MEDICAL TOURISM IN THE MIDDLE EAST... 96 RUSSIAN HEALTHCARE SYSTEMS... 96 HEALTHCARE IN RUSSIA... 97 TABLE 29 TOTAL EXPENDITURE ON HEALTHCARE AS A SHARE OF GDP IN SELECTED EMRA COUNTRIES, 2009 ($ MILLIONS/%)... 98 TABLE 30 PROJECTED EMRA MARKET FOR CATHETERS BY REGION, THROUGH 2016 ($ MILLIONS)... 99 TABLE 31 PROJECTED EMRA MARKET FOR CATHETERS BY TYPE, THROUGH 2016 ($ MILLIONS)... 100 GOVERNMENT REGULATIONS... 100 MARKET GROWTH IN EMRA COUNTRIES... 100 ECONOMIC CONDITIONS... 101 CARDIOVASCULAR MARKET... 101 TABLE 32 PROJECTED EMRA MARKET FOR CARDIOVASCULAR CATHETERS, THROUGH 2016 ($ MILLIONS)... 102 TRENDS IN THE EMRA CARDIOVASCULAR CATHETER MARKET... 102 UROLOGY CATHETER MARKET... 102 TABLE 33 PROJECTED EMRA MARKET FOR UROLOGICAL CATHETERS, THROUGH 2016 ($ MILLIONS)... 103 TRENDS IN THE EMRA UROLOGICAL CATHETER MARKET... 103 INTRAVENOUS CATHETER MARKET... 103 TABLE 34 PROJECTED EMRA MARKET FOR INTRAVENOUS CATHETERS, THROUGH 2016 ($ MILLIONS)... 103 TRENDS IN THE EMRA INTRAVENOUS CATHETER MARKET... 104 NEUROVASCULAR CATHETER MARKET... 104 TABLE 35 PROJECTED EMRA MARKET FOR NEUROVASCULAR CATHETERS, THROUGH 2016 ($ MILLIONS)... 104 TRENDS IN THE EMRA NEUROVASCULAR CATHETER MARKET... 104 SPECIALTY CATHETER MARKET... 105 TABLE 36 PROJECTED EMRA MARKET FOR SPECIALTY CATHETERS, THROUGH 2016 ($ MILLIONS)... 105 TRENDS IN THE EMRA SPECIALTY CATHETER MARKET... 105 CHAPTER NINE: THE ASIAN CATHETER MARKET... 106 REGIONAL ECONOMIC CONSIDERATIONS... 106 TABLE 37 PROJECTED ASIAN CATHETER MARKET, THROUGH 2016 ($ MILLIONS)... 106 GDP AND GROWTH RATES... 107 TABLE 38 GDP OF SELECTED ASIAN COUNTRIES, GDP GROWTH RATE, PERCENT OF GDP DEVOTED TO HEALTHCARE... 107
REGULATIONS AND HEALTHCARE COVERAGE IN THE AUSTRALIAN MARKET... 107 Health Insurance in Australia... 108 REGULATIONS AND HEALTHCARE COVERAGE IN THE JAPANESE MARKET... 108 REGULATIONS AND HEALTHCARE COVERAGE IN THE INDIAN MARKET... 108 Medical Insurance in India... 109 Growth of the Indian Healthcare Industry... 109 REGULATIONS AND HEALTHCARE COVERAGE IN THE CHINESE MARKET... 109 Medical Device Regulations... 109 Chinese Healthcare Institutions... 110 Rural and Urban Healthcare Services... 110 ASIAN CATHETER MARKET BY TYPE OF PRODUCT... 111 TABLE 39 PROJECTED ASIAN CATHETER MARKET BY PRODUCT TYPE, THROUGH 2016 ($ MILLIONS)... 111 CARDIOVASCULAR MARKET... 111 TABLE 40 PROJECTED ASIAN CARDIOVASCULAR CATHETER MARKET, THROUGH 2016 ($ MILLIONS)... 112 Trends in the Asian Cardiovascular Catheter Market... 112 UROLOGY CATHETER MARKET... 112 TABLE 41 PROJECTED ASIAN UROLOGY CATHETER MARKET, THROUGH 2016 ($ MILLIONS)... 113 Trends in the Asian Urological Catheter Market... 113 INTRAVENOUS CATHETER MARKET... 113 TABLE 42 PROJECTED ASIAN INTRAVENOUS CATHETER MARKET, THROUGH 2016 ($ MILLIONS)... 113 Trends in the Asian IV Catheter Market... 114 NEUROVASCULAR CATHETER MARKET... 114 TABLE 43 PROJECTED ASIAN NEUROVASCULAR CATHETER MARKET, THROUGH 2016 ($ MILLIONS)... 114 Trends in the Asian Neurological Catheter Market... 114 SPECIALTY CATHETER MARKET... 115 TABLE 44 PROJECTED ASIAN SPECIALTY CATHETER MARKET, THROUGH 2016 ($ MILLIONS)... 115 Trends in the Asian Specialty Catheter Market... 115 CHAPTER TEN: PATENT ANALYSIS... 116 GLOBAL CATHETER PATENT APPLICATIONS, 2008-2011... 116 TABLE 45 GLOBAL CATHETER PATENT APPLICATIONS, 2008-2011... 117 CATHETER PATENT ACTIVITY BY ASSIGNEE... 117 TABLE 46 CATHETER PATENT APPLICATION ACTIVITY BY ASSIGNEE, JANUARY 2008-SEPTEMBER 2011 (NUMBER OF PATENTS)... 117
TABLE 46 (CONTINUED)... 118 CARDIOVASCULAR CATHETER PATENTS... 118 TABLE 47 CARDIOVASCULAR CATHETER PATENTS BY TYPE, JANUARY 2008-SEPTEMBER 2011... 118 TABLE 48 CARDIAC CATHETER PATENTS, NOVEMBER 2011- JANUARY 2008... 119 TABLE 48 (CONTINUED)... 120 TABLE 48 (CONTINUED)... 121 TABLE 48 (CONTINUED)... 122 TABLE 49 BALLOON CATHETER PATENTS, APRIL 2011-JANUARY 2008... 122 TABLE 49 (CONTINUED)... 123 TABLE 50 CARDIAC GUIDE CATHETER PATENTS, NOVEMBER 2011-JANUARY 2008... 123 TABLE 51 CARDIAC GUIDEWIRE PATENTS, 2010... 124 UROLOGY CATHETER PATENTS... 124 IV CATHETER PATENTS... 124 TABLE 52 IV CATHETER PATENTS BY TYPE, JANUARY 2008- SEPTEMBER 2011... 124 TABLE 53 IV CATHETER PATENTS, JUNE 2009-SEPTEMBER 2008... 125 SPECIALTY CATHETER PATENTS... 125 TABLE 54 SPECIALTY CATHETER PATENTS BY TYPE, JANUARY 2008-SEPTEMBER 2011... 126 TABLE 55 SPECIALTY CATHETER PATENTS, OCTOBER 2011- JANUARY 2008... 126 TABLE 55 (CONTINUED)... 127 CATHETER COATINGS... 128 TABLE 56 CATHETER COATING PATENTS, JANUARY 2008- SEPTEMBER 2011... 128 TABLE 57 CATHETER COATING PATENTS, JULY 2011-JUNE 2009... 128 TABLE 57 (CONTINUED)... 129 CHAPTER ELEVEN: COMPANY DIRECTORY... 130 ABBOTT LABORATORIES... 130 BUSINESS OVERVIEW... 130 FINANCIAL... 130 PRODUCTS... 131 TABLE 58 ABBOTT LABORATORIES CATHETER PRODUCTS... 131 ANGIODYNAMICS... 131 BUSINESS OVERVIEW... 131 FINANCIALS... 132 PRODUCTS... 132 TABLE 59 ANGIODYNAMICS CATHETER PRODUCTS... 132 ASTRA TECH INC., UROLOGY DIVISION... 132 BUSINESS OVERVIEW... 133
FINANCIALS... 133 PRODUCTS... 133 TABLE 60 ASTRA TECH CATHETER PRODUCTS... 133 B. BRAUN MELSUNGEN AG... 134 BUSINESS OVERVIEW... 134 FINANCIALS... 134 PRODUCTS... 134 TABLE 61 B. BRAUN CATHETER PRODUCTS... 134 TABLE 61 (CONTINUED)... 135 BECTON DICKINSON & CO.... 135 BUSINESS OVERVIEW... 135 FINANCIALS... 136 PRODUCTS... 136 TABLE 62 BD CATHETER PRODUCTS... 136 BOSTON SCIENTIFIC... 136 BUSINESS OVERVIEW... 137 FINANCIALS... 137 PRODUCTS... 137 TABLE 63 BOSTON SCIENTIFIC CATHETER PRODUCTS... 137 TABLE 63 (CONTINUED)... 138 CARDINAL HEALTH... 138 BUSINESS OVERVIEW... 138 FINANCIALS... 139 PRODUCTS... 139 TABLE 64 CARDINAL HEALTH CATHETER PRODUCTS... 139 CAREFUSION CORP.... 139 BUSINESS OVERVIEW... 140 FINANCIALS... 140 PRODUCTS... 140 TABLE 65 CAREFUSION CATHETER PRODUCTS... 140 CODMAN & SHURTLEFF (DEPUY)... 140 BUSINESS OVERVIEW... 140 FINANCIALS... 141 PRODUCTS... 141 TABLE 66 CODMAN & SHURTLEFF CATHETER PRODUCTS... 141 COLOPLAST GROUP... 141 FINANCIALS... 142 PRODUCTS... 142 TABLE 67 COLOPLAST CATHETER PRODUCTS... 142 COOK MEDICAL... 142 BUSINESS OVERVIEW... 142 FINANCIALS... 143 PRODUCTS... 143 TABLE 68 COOK MEDICAL CATHETER PRODUCTS... 143
TABLE 68 (CONTINUED)... 144 COVIDIEN... 144 BUSINESS OVERVIEW... 144 FINANCIALS... 144 PRODUCTS... 145 TABLE 69 COVIDIEN CATHETER PRODUCTS... 145 C. R. BARD... 146 BUSINESS OVERVIEW... 146 FINANCIALS... 146 PRODUCTS... 146 TABLE 70 C. R. BARD CATHETER PRODUCTS... 146 TABLE 70 (CONTINUED)... 147 TABLE 70 (CONTINUED)... 148 EDWARDS LIFESCIENCES... 148 BUSINESS OVERVIEW... 148 FINANCIALS... 148 PRODUCTS... 149 TABLE 71 EDWARDS LIFESCIENCES CATHETER PRODUCTS... 149 EV3 ENDOVASCULAR INC. (COVIDIEN)... 149 BUSINESS OVERVIEW... 149 FINANCIALS... 149 PRODUCTS... 150 TABLE 72 EV3 CATHETER PRODUCTS... 150 GOODMAN CO. LTD... 150 BUSINESS OVERVIEW... 150 FINANCIALS... 151 PRODUCTS... 151 TABLE 73 GOODMAN CATHETER PRODUCTS... 151 HOLLISTER... 151 BUSINESS OVERVIEW... 151 FINANCIALS... 151 PRODUCTS... 152 TABLE 74 HOLLISTER CATHETER PRODUCTS... 152 HOSPIRA INC.... 152 BUSINESS OVERVIEW... 152 FINANCIALS... 152 PRODUCTS... 152 TABLE 75 HOSPIRA CATHETER PRODUCTS... 152 ICU MEDICAL... 153 BUSINESS OVERVIEW... 153 FINANCIALS... 153 PRODUCTS... 153 TABLE 76 ICU MEDICAL CATHETER PRODUCTS... 153 INTEGRA LIFE SCIENCES... 154
BUSINESS OVERVIEW... 154 FINANCIALS... 154 PRODUCTS... 154 TABLE 77 INTEGRA LIFESCIENCES CATHETER PRODUCTS... 154 JOHNSON & JOHNSON... 154 BUSINESS OVERVIEW... 155 FINANCIALS... 155 PRODUCTS... 155 TABLE 78 JOHNSON & JOHNSON CATHETER PRODUCTS... 155 TABLE 78 (CONTINUED)... 156 KIMBERLY CLARK HEALTHCARE... 156 BUSINESS OVERVIEW... 156 FINANCIALS... 157 PRODUCTS... 157 TABLE 79 KIMBERLY CLARK HEALTHCARE CATHETER PRODUCTS... 157 MEDCOMP... 157 BUSINESS OVERVIEW... 157 FINANCIALS... 157 PRODUCTS... 158 TABLE 80 MEDCOMP CATHETER PRODUCTS... 158 MEDLINE INDUSTRIES... 158 BUSINESS OVERVIEW... 158 FINANCIALS... 159 PRODUCTS... 159 TABLE 81 MEDLINE CATHETER PRODUCTS... 159 MEDRAD (BAYER AG)... 159 BUSINESS OVERVIEW... 159 FINANCIALS... 160 PRODUCTS... 160 TABLE 82 MEDRAD CATHETER PRODUCTS... 160 MEDTRONIC... 160 BUSINESS OVERVIEW... 160 FINANCIALS... 161 PRODUCTS... 161 TABLE 83 MEDTRONIC CATHETER PRODUCTS... 161 MERIT MEDICAL SYSTEMS... 162 BUSINESS OVERVIEW... 162 FINANCIALS... 162 PRODUCTS... 162 TABLE 84 MERIT MEDICAL CATHETER PRODUCTS... 162 TABLE 84 (CONTINUED)... 163 NAVILYST MEDICAL... 163 BUSINESS OVERVIEW... 163 FINANCIALS... 163
PRODUCTS... 164 TABLE 85 NAVILYST MEDICAL CATHETER PRODUCTS... 164 PULSION MEDICAL AG... 164 BUSINESS OVERVIEW... 164 FINANCIALS... 164 PRODUCTS... 165 TABLE 86 PULSION MEDICAL SYSTEMS CATHETER PRODUCTS... 165 ROCHESTER MEDICAL... 165 BUSINESS OVERVIEW... 165 FINANCIALS... 165 PRODUCTS... 166 TABLE 87 ROCHESTER MEDICAL CATHETER PRODUCTS... 166 SMITHS MEDICAL... 166 BUSINESS OVERVIEW... 166 FINANCIALS... 167 PRODUCTS... 167 TABLE 88 SMITHS MEDICAL CATHETER PRODUCTS... 167 ST. JUDE MEDICAL... 168 BUSINESS OVERVIEW... 168 FINANCIALS... 168 PRODUCTS... 168 TABLE 89 ST. JUDE MEDICAL CATHETER PRODUCTS... 168 TABLE 89 (CONTINUED)... 169 STRYKER... 169 BUSINESS OVERVIEW... 169 FINANCIALS... 170 PRODUCTS... 170 TABLE 90 STRYKER CATHETER PRODUCTS... 170 TELEFLEX MEDICAL (FORMERLY ARROW INTERNATIONAL)... 170 BUSINESS OVERVIEW... 170 FINANCIALS... 171 PRODUCTS... 171 TABLE 91 TELEFLEX CATHETER PRODUCTS... 171 TERUMO MEDICAL CORP.... 172 BUSINESS OVERVIEW... 172 FINANCIALS... 172 PRODUCTS... 172 TABLE 92 TERUMO CATHETER PRODUCTS... 172 TABLE 92 (CONTINUED)... 173 VASCULAR SOLUTIONS... 173 BUSINESS OVERVIEW... 173 FINANCIALS... 174 PRODUCTS... 174 TABLE 93 VASCULAR SOLUTIONS CATHETER PRODUCTS... 174
VOLCANO CORPORATION... 174 BUSINESS OVERVIEW... 174 FINANCIALS... 175 PRODUCTS... 175 TABLE 94 VOLCANO CORPORATION CATHETER PRODUCTS... 175 APPENDIX: CATHETER PRODUCTS AND THEIR MANUFACTURERS... 176 TABLE 95 CATHETER PRODUCTS BY APPLICATION, TYPE, BRAND NAME, AND MANUFACTURER... 176 TABLE 95 (CONTINUED)... 177 TABLE 95 (CONTINUED)... 178 TABLE 95 (CONTINUED)... 179 TABLE 95 (CONTINUED)... 180 TABLE 95 (CONTINUED)... 181 TABLE 95 (CONTINUED)... 182 TABLE 95 (CONTINUED)... 183 TABLE 95 (CONTINUED)... 184 TABLE 95 (CONTINUED)... 185 TABLE 95 (CONTINUED)... 186 TABLE 95 (CONTINUED)... 187 TABLE 95 (CONTINUED)... 188 TABLE 95 (CONTINUED)... 189 TABLE 95 (CONTINUED)... 190 TABLE 95 (CONTINUED)... 191 TABLE 95 (CONTINUED)... 192 TABLE 95 (CONTINUED)... 193