Early Age Onset Colorectal Cancer. New York. Saturday, March 21. EAO-CRC 2015 THE NATION S FIRST ANNUAL

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Are Pleased to Jointly Sponsor THE NATION S FIRST ANNUAL Early Age Onset Colorectal Cancer S U M M I T Saturday, March 21 CONFERENCE LOCATION Memorial Sloan Kettering Cancer Center ROCKEFELLER RESEARCH LABORATORIES 430 East 67th Street, between First and York Avenues New York Please register today at:

COURSE OVERVIEW This summite launches an annual forum dedicated to understanding the causes of early age onset colorectal cancer; reducing the incidence and increasing survival of the disease as well as improving the quality of life of survivors and their families. The course is designed for Early Age Onset (EAO) colorectal cancer (CRC) survivors as well as physicians and scientists who are interested in advancing their understanding of the rapidly increasing incidence of rectal and colon cancer prior to 50 years of age. The program will provide an opportunity to hear leading clinicians and scientists on the epidemiology, pathogenesis, genomics and lifestyle challenges of EAO-CRC. The course will include lectures as well as workshops and panel discussions designed to facilitate multidisciplinary consensus regarding the priorities of EAO-CRC prevention, clinical care and research moving forward. EDUCATIONAL AND SUMMIT OBJECTIVES Review the epidemiology, diagnosis and treatment of young adult colorectal cancers. Discuss the current state of knowledge on the causes of young adult colorectal cancer and identify specific gaps in that knowledge. Provide an evidence based framework for reducing risk, increasing early stage diagnosis and improving treatment and quality of life for these patients.

FACULTY HOST & SUMMIT ORGANIZER Thomas K. Weber MD FACS State University of New York at Downstate President Colon Cancer Challenge Foundation COURSE CO-DIRECTOR Robin Mendelsohn MD MSK Gastroenterology and Nutrition Service Cornell University KEY NOTE SPEAKER Rebecca Siegel MPH American Cancer Society GUEST FACULTY Mary Bassett MD MPH NYC Commissioner of Health Nancy You MD MD Anderson Cancer Center Jiyoung Ahn PhD NYU Division of Epidemiology Department of Population Sciences Fay Kastrinos MD MPH Columbia University Medical Center Kate McNamara MD University of Toronto Susan Peterson PhD MPH MD Anderson Cancer Center Martha Raymond MA CPN The Raymond Foundation

Saturday, March 21 11:00am-12:00pm REGISTRATION 12:00-12:15pm 12:15-12:30pm 12:30-1:00pm WELCOME LUNCHEON Overview of the Day and Introductions Tom Weber MD A Novel Public Health Opportunity Mary Bassett MD MPH KEYNOTE SPEAKER Incidence of Colorectal Cancer in Young Adults in the United States: The Current State of the Problem Rebecca Siegel PhD 1:00-1:20pm The Clinical Challenges of EAO: Reducing Late Stage Diagnosis; Improving Treatment and Long Term Survival Nancy You MD 1:20-1:40pm The Contribution of the Known Hereditary Colorectal Cancer Syndromes to the Incidence of Young Adult Colorectal Cancer Fay Kastrinos MD 1:40-2:00pm 2:00-2:20pm 2:20-2:40pm BREAK Whole Genome Sequencing in Early Age Onset Colorectal Cancer: The Toronto Cohort Kate McNamara MD The Microbiome and EAO CRC Jiyoung Ahn PhD

Saturday, March 21 2:40-3:00pm 3:00-3:20pm 3:20-3:40pm 3:40-4:00pm Defining the True Risk Factors for EAO/CRC: A 21st Century Epidemiology Challenge Thomas Weber MD Quality of Life after a EAO Diagnosis & Protecting those you Love Susan Petersen PhD The Patient Perspective: Exploring the New Normal of The Young Colon Cancer Patient Martha Raymond MA CPN BREAK PRIORITY NEXTSTEPS WORKSHOPS 4:00-4:45pm 4:00-4:45pm 5:00-5:30pm 5:30-6:30pm WORKSHOP I Medical & Scientific Community Facilitated Discussion of Research Priorities: Consensus Goals & Next Steps WORKSHOP II Medical & Scientific Community Facilitated Discussion of Research Priorities: Consensus Goals & Next Steps CONCENSUS FORUM Groups Return For Report Back: Summary of Priorities and Next Steps Moving Forward Including Next Summit PRESIDENT S WINE & CHEESE RECEPTION

REGISTRATION $180 MDs, PhDs, DOs, Residents $150 Physician Assistants, Nurse Practitioners $100 Practice Managers $36 Patient / Survivor Advocates, Fellows, Student, Interns, Residents $30* President s Reception 5-6pm Saturday *For those not attending the summit. Registration fee includes an electronic syllabus and other related hand-out materials, continental breakfast, lunch, refreshment breaks and President s Wine & Cheese Reception immediately following the Summit. Special meals are available upon request, including vegetarian, kosher, or gluten-free. Please let us know if we can assist you with special dietary needs. To register to attend please go to: Or contact: OFFICE OF CONTINUING MEDICAL EDUCATION Memorial Sloan Kettering Cancer Center 633 Third Avenue, 12th floor, New York, New York 10017 (646) 227-2025 brodheap@mskcc.org TARGET AUDIENCE EAO CRC Survivors. EAO Health Services Providers and Researchers. COURSE DESIGN The course will include lectures as well as workshops and panel discussions designed to facilitate multidisciplinary consensus regarding the priorities of EAO-CRC prevention, clinical care and research moving forward. EVALUATION A course evaluation survey sent out electronically will provide attendees with the opportunity to review the sessions and the speakers and to identify future educational needs. OUTCOMES MEASUREMENT SURVEY Six months after the end of the course an Outcomes Measurement Survey will be sent to all participants to help us determine what positive impacts have been made on participant practice as a result of the course. FACULTY DISCLOSURE It is the policy of MSK to make every effort to insure balance, independence, objectivity, and scientific rigor in all continuing medical education activities which it sponsors as an ACCME accredited provider. In accordance with ACCME guidelines and standards, all faculty participating in an activity sponsored by MSK are expected to disclose any significant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services which are discussed by the faculty members in an educational presentation. As required by the ACCME, when an unlabeled use of a commercial product or an investigational use not yet approved for any purpose is discussed during an educational activity, MSK requires the speaker to disclose that the product is not labeled for the use under discussion or that the product is still investigational.

Please be sure to mark your calendars for upcoming 2015 MSK CME COURSES ACCREDITATION STATEMENT MSK is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians. For course updates, follow: facebook.com/mskcme or on Twitter: @mskcme Advanced Breast Imaging March 6-8 HemOnc Board Review March 6-9 YOUNG ADULT COLORECTAL MARCH 21 CANCER SUMMIT Multidisciplinary April 16-17 Spine Oncology SCLC Meeting April 22-24 Pelvic MRI Course April 27-29 Aging in Cancer May 1 Pathology of Neoplastic May 4-8 Disease Modern Radiation May 7-9 for Lymphoma Oncologic Imaging May 14-16 Disease Management Thrombosis and Hemostasis May 17 Radioactive Seed Loacation May 22 International Ovarian Cancer June 5-6 Thoracic Pathology September 11-13 Robotics in Gynecologic September 17-18 Surgery Interventional Pulmonology September 24-25 Thoracic Surgery October 2-3 Oncologic FDG PET/CT October 15-16 Breast Cancer October 16-17 Dermoscopy October 16-17 Myeloproliferative Neoplasms October 18 Dermatologic Care October 23 Musculoskeletal Tumor October 23-25 Pathology Urology Centennial October 29-31 To register or for more information, contact: OFFICE OF CONTINUING MEDICAL EDUCATION Memorial Sloan Kettering Cancer Center 633 Third Avenue, 12th Floor, New York, New York 10017 (646) 227-2025 brodheap@mskcc.org Or register online: www.mskcc.org/cme