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presents ONCOPLASTIC BREAST MEETING MILANO, 13 th - 16 th DECEMBER 2017 Meeting Venue: Auditorium GRUPPO 24 ORE Via Monte Rosa, 91 Milano (area Fiera Milanocity)

programme WEDNESDAY 13 th DECEMBER 2017 08.00/11.00_Registration 10.50/11.00 OPENING AND CONFERENCE INTRODUCTION PRE-CONFERENCE COURSES Pre-conference Workshops Pills of Oncoplastic Breast Surgery (Chairman: A. Rancati) 11.00/11.25 Planning Oncoplastic Surgery: Past - Present - Future (W. Audretsch) 11.25/12.00 Planning an implant based breast reconstruction: two stages and DTI. Surgical procedures to improve the final outcome (video-lecture) (M. Brown) 12.00/12.20 Planning an autologous flap and fat transplantation (C. Andree) 12.20/12.45 Latissimus Dorsi surgical procedures (video-lecture) (D. Hammond) 12.45/13.00 (Discussant: D. Hammond) Breast Reconstruction and Complications (Chairman: M. Brown) 13.00/13.50 Bacterial Biofilm and breast implant infection, capsular contracture, late seromas and BIA-ALCL (M. Clemens) 13.50/14.10 Breast implant surgery: common complications in two stages and DTI: how to prevent and how to treat 14.10/14.30 Autologous Tissue Surgery: common complications in the use of flaps and fat: how to prevent and how to treat (C. Andree) 14.30/14.50 Shear wave elastosonography for prediction of axillary involvement and response to neoadjuvant chemotherapy (A. Evans) 14.50/15.10 Recovering from poor outcome in Oncoplastic Surgery 15.10/15.30 Molecular biomarkers and DCIS (M. Carcangiu) 15.30/15.45 (Discussant: M. Brown) { 15.45/16.20_Coffee break } GUEST LECTURES Introducer: M.B. Nava 16.20/16.50 Overdoing in breast surgery (V. Sacchini) 16.50/17.20 Treatment of low-risk ductal carcinoma in situ (J. Benson) 17.20/17.50 Neo-adjuvant pertuzumab and trastuzumab. The Neo-Sphere: a multicenter randomized trial (L. Gianni) 17.50/18.20 The evolution of implant-based breast reconstruction (P. Cordeiro) 18.20/18.40 FELLOWSHIP G. QUERCI DELLA ROVERE LECTURE Introducer: (G. Catanuto) 18.40/18.55 CONFERENCE PRESIDENT GREETINGS { 19.00_Welcome Cocktail } THURSDAY 14 th DECEMBER 2017 SURGICAL ONCOLOGY SESSION Breast conservation (Chairman: M. Douek) 08.00/08.15 Surgical and patient-reported outcomes after therapeutic mammaplasties and wide local excision (J. Rusby) 08.15/08.30 Intraoperative ultrasound guidance in breast conserving surgery a randomized controlled trial (COBALT) (M.P. Van den Tol)

08.30/08.45 Breast conservative treatment in association with implant augmentation and intraoperative radiotherapy (P. Veronesi) 08.45/09.00 Intraoperative assessment of margins (M. Douek) 09.00/09.15 (Discussant: M. Douek) 09.15/09.40 KEYNOTE VIDEO-TEACHING LECTURE How to reshape the breast after wide resection has been performed in all the quadrants (R. De Vita) 09.40/10.00 HOT-TOPIC LECTURE Preoperative cryoablation-mediated tumor antigen presentation and/or ipilimumab-mediated immune modulation in women with operable breast cancer (V. Sacchini) 10.00/10.30 Face to Face: DTI Pre-Pectoral: clinic data on two different ADM (G. Berna - J. Murphy) { 10.30/11.00_Coffee break } Neoadjuvant systemic therapies (Chairman: L. Del Mastro) 11.00/11.15 Primary systemic therapies (M. Harries) 11.15/11.30 Breast conserving surgery after primary systemic therapies (M. Douek) 11.30/11.45 Primary systemic therapies and axillary management: the evidence (J. Benson) 11.45/12.00 The breast boost after neoadjuvant chemotherapy (L. Lozza) 12.00/12.15 (Discussants: L. Del Mastro - L. Lozza) 12.15/12.40 KEYNOTE VIDEO-LECTURE How to obtain aesthetic outcome in implant based breast reconstruction: my vision (R. De Vita) 12.40/13.00 HOT TOPIC LECTURE Aesthetic breast surgery associated cancer: Breast conservation - Conservative mastectomy (W. Audretsch) { 13.00/14.00_Lunch } 14.00/14.20 KEYNOTE LECTURE Immunotherapy for breast cancer: hope or hype? (M. De Laurentis) 14.20/15.00 VIDEO TEACHING SESSION Contra-lateral breast symmetrization (D. Hammond - A. Rancati) Conservative mastectomies and implant-based breast reconstruction (Chairman: Z. Winters) 15.00/15.15 NAC-sparing mastectomies. The Italian National Registry (L. Orzalesi) 15.15/15.30 Personal experience with various ADM materials (M. Brown) 15.30/15.45 Alternatives to dermal matrices or autografts (S. Folli) 15.45/16.00 Robotic surgery: real tool or momentary fashion (A. Toesca) 16.00/16.10 (Discussants: N. Rocco - Z. Winters) { 16.10/16.40_Coffee break } Evidence-Based Oncoplastic Breast Surgery (Chairman: N. Rocco) 16.40/17.00 The evidence behind Guidelines in Breast Cancer Treatment (I. Moschetti) 17.00/17.15 Systematic reviews in surgery: Cochrane Collaboration Criteria (L. Moja) 17.15/17.30 Methodological Aspects in Evidence Based Surgery (P. Chiodini) 17.30/17.45 Cochrane systematic reviews: evidences in implant based breast reconstruction (N. Rocco)

17.45/17.55 (Discussant: N. Rocco) 17.55/18.35 KEYNOTE LECTURES Pregnancy and breast cancer (L. Del Mastro) Breast cancer and nutrition: to prevent and to support (F. Berrino) 18.35/19.00 Live-simulation: Oncoplastic breast conserving surgery implant-based breast reconstruction surgical planning (G. Catanuto - D. Hammond - A. Rancati) FRIDAY 15 th DECEMBER 2017 Risk reduction surgery (Chairman: J. Benson) 08.00/08.15 Genetic risk assessment (A. De Nicolo) 08.15/08.30 Contra-lateral mastectomy after breast cancer (J. Benson) 08.30/08.45 Quality of life after risk reduction (Z. Winters) 08.45/08.55 (Discussants: C. Borreani - A. De Nicolo) 08.55/09.20 KEYNOTE LECTURES The going flat choice: current reasons for rejecting reconstruction (C. Borreani) Patients selection and personal thought for different surgical procedures trough DTI (Chairman: M. Brown) 09.20/09.35 Epi-Pectoral breast reconstructions with ADM (A. Gabriel) 09.35/09.50 Epi-pectoral breast reconstructions with synthetic mesh (D. Casella) 09.50/10.05 Pre-Pectoral DTI for a painless post-operative recovery and natural aesthetic outcomes (M. Salgarello) 10.05/10.20 Dual Plane and ADM (D. Hammond) 10.20/10.35 Dual plane and no meshes 10.35/10.45 (Discussants: M. Brown - A. Rancati) { 10.45/11.15_Coffee break } FAT ASSISTED KEYNOTE LECTURES 11.15/11.40 Reproducible Volume Restoration and Efficient. Long-term volume retention after point-of-care standardized cell-enhanced fat grafting in breast surgery (R. Llull) 11.40/12.00 Bioengineered breast/hybrid breast: concept, technique and preliminary results (A. Gabriel) 12.00/12.20 How the fat cell transplantation change my surgical approach (P. Blondeel) 12.20/13.00 Face to Face: Two stages VS DTI (Chairmen: P. Cordeiro VS A. Rancati) { 13.00/14.00_Lunch } Pearls on breast reconstruction: The NAC 14.00/14.15 Personal technique (D. Hammond) 14.15/14.30 External prosthetic NAC 14.30/14.45 Tattoo for NAC reconstruction (U. De Lucia) 14.45/15.15 HOT TOPIC LECTURES Polland Syndrome: classification and treatment (P. Santi) Eexternal expansion and fat grafting (M. Brown) 15.15/15.45 Young guns meet the experts on Multi-Disciplinary-Team setting (Chairman: G. Catanuto) (Team: G. Bianchi - M.L. Carcangiu - M. Douek - S. Folli M. Harries - L. Lozza) 15.45/16.00 Quality of Life after Breast Cancer Treatments (Chairman: Z. Winters) 15.45/16.00 Prevention and treatment of scars (P. Ferrando) MBN2017

16.00/16.15 Arm lymphedema treatment with abdominal flaps (M. Salgarello) 16.15/16.30 Feasibility of cosmetic procedures in cancer patients: when and what { 16.30/17.00_Coffee break } Overdoing in Breast Cancer: the risks of over screening, over-diagnosing and over-treating the disease (Chairman: A. Rancati) 17.00/17.15 Over screening and diagnosis in breast imaging (A. Evans) 17.15/17.30 Over using chemotherapy in the adjuvant setting (L. Del Mastro) 17.30/17.45 Over irradiation (J. Jassem) 17.45/18.00 Over using oncoplastic-surgery in breast cancer (G. Catanuto) 18.00/18.15 Autologous Flaps over-reconstruction or gold standard: data from patient reported outcome measurements (A. Pusic) 18.15/18.20 (Summarizer: A. Rancati) 18.20/18.40 KEYNOTE LECTURE Do we really know and are we really in control of our decisions? (G. Pravettoni) 18.40/19.00 KEYNOTE LECTURE Quality of life after breast reconstruction and adjuvant treatments (Z. Winters) SATURDAY 16 th DECEMBER 2017 CONSENSUS CONFERENCE RADIOTHERAPY AND BREAST RECONSTRUCTION (Chairmen: M.B. Nava - A. Spano) Pre-Consensus LECTURES 08.00/08.20 RT and reconstruction (J. Jassem) 08.20/08.40 Should immediate autologous breast reconstruction be considered in women who require post mastectomy radiation therapy? A prospective analysis of outcomes (A. Pusic) 08.40/09.05 Tailored radiation therapy for breast cancer (R. Orecchia) 09.05/09.15 Implant based breast reconstruction in radio-treated patients: personal experience (P. Cordeiro) 09.15/09.35 Radiotherapy and soft tissue breast reconstruction: from flaps to fat (P. Blondeel) 09.35/09.55 Pre-surgical radio therapy (PRT i.e. neo-adjuvant ) and post-radiation reconstruction: Planning and Techniques (W. Audretsch) 10.00/12.00 DEABATES ON RADIOTHERAPY AND BREAST RECONSTRUCTION (M.B. Nava - N. Rocco) INVITED SPEAKERS: W. Audretsch - P. Blondeel - M. Brown G. Catanuto - M. Clemens - P. Cordeiro R. De Vita - A. Gabriel - D. Hammond - J. Jassem L. Lozza - R. Orecchia - A. Pusic - A. Spano - Z. Winters 12.00/12.15 Doses distribution after expander insertion (L. Lozza) 12.15/12.30 Does radiotherapy affect implant integrity? (S. Farè) 12.30/12.50 Breast Detection after Oncoplastic peocedeures in Radiotreated patients. (G. Scaperrotta) 12.50/13.00 CONSENSUS CONFERENCE - CONCLUSIONS Consensus Paper Chairmen: (M.B. Nava - A. Rancati - N. Rocco) 13.00/13.30 MASTER LECTURE (M.B. Nava) 13.30/13.45 CLOSING AND REMARKS 13.45 Farewell Lunch

GENERAL INFORMATION MBN2017 Maurizio Bruno Nava ORGANIZING SECRETARIAT MZ Congressi Via C. Farini, 81-20159 Milano - (Italy) Phone +39 02 66802323 - Fax +39 02 6686699 congress@maurizionava.it (during the conference, it is not permitted to film or take pictures of the speakers and/or their presentations) Next meetings: Aesthetic Breast Surgery: December 13/15.2018 Oncoplastic Breast Meeting: December 11/14.2019 Aesthetic Breast Surgery: December 10/12.2020 Oncoplastic Breast Meeting: December 15/18.2021 Save the dates! powered by