HEADS UP REAL NEWS ABOUT DRUGS AND YOUR BODY

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HEADS UP REAL NEWS ABOUT DRUGS AND YOUR BODY A Message from Scholastic and the National Institute on Drug Abuse (NIDA) You probably know that drugs that don t come from a pharmacy or other legal distributor can be dangerous. But they also may not be what they seem. IN RECENT YEARS, emergency room doctors have reported a growing number of overdoses related to the use of certain types of synthetic drugs. Most drugs even the ones that help people are synthetic, which means that they re produced by mixing and creating chemicals in laboratories. The ones that are prescribed by doctors and bought in pharmacies or other legal retailers are tested to make sure that they are safe. But now synthetic drugs are also being made in illegal or unregulated laboratories, mostly in foreign countries. The makers of these drugs create chemicals that act like other drugs, such as marijuana or prescription pain medications. The drugs are then sold on the street, online, or in gas stations or other stores, and are often marked with misleading labels.

While many drugs pose a risk for addiction and overdose if they are misused, these counterfeit synthetic drugs can carry additional risks. There is no way to know what chemicals the drugs contain or in what amounts. A product bought on the street or online may look the same as a familiar drug. It may even look identical to a pill a person DANGEROUS EFFECTS OF SYNTHETIC DRUGS OPIOIDS Example: Fentanyl Opioids are powerful drugs that doctors prescribe to relieve pain. They can be extremely addictive and even deadly if they are misused. Fentanyl is a synthetic opioid that is much stronger than other opioids. It is prescribed only to treat extreme pain in patients with cancer or following surgery. Recently, there has been a rise in the illegal production of fentanyl. Illegally made fentanyl is often mixed with other drugs or hidden in fake prescription medications that are sold on the street. Users may not know they are taking it. A surge in deadly overdoses related to opioids has been linked in part to products that contain hidden fentanyl. It is never safe to take prescription drugs that are not prescribed for you or that are bought anywhere other than at an official pharmacy because you don t know what chemicals they really contain. CANNABINOIDS Examples: Spice, K2 Often called synthetic marijuana, these drugs are made of dried plant material that is sprayed with chemicals. These chemicals, called synthetic cannabinoids, are similar to THC, the main active ingredient in marijuana. But they are much more powerful than THC. The drugs can cause paranoia and violent behavior as well as serious health problems, including seizures, heart attacks, and death. Studies have also shown that the drug called Spice can be addictive. 130 people were treated over three days in New York City in 2016 for overdosing on synthetic cannabinoids. Health officials believe that the cause was a powerful batch of K2. Because the laboratories that make these products are not regulated, each batch can be very different, even if the packaging looks the same. would buy in a pharmacy. But the drugs can contain completely different chemicals and be much more powerful, and potentially deadly. Read the sidebar below to learn more about the dangers of counterfeit synthetic drugs. Bottom line: Never take any prescription drug that is not prescribed for you and is not bought in a pharmacy. CATHINONES Example: Bath Salts Fake bath salts are different from the products used in your bathtub. These bath salts are synthetic drugs that contain chemicals called cathinones, which are designed to be similar to stimulant drugs such as amphetamine and MDMA (also known as Ecstasy or Molly). But these drugs can have more powerful effects. They can increase heart rate and blood pressure as well as cause hallucinations and paranoia. Intense cravings have been reported by people who use bath salts. That s a sign that they have become dependent on the drug. Makers of illegal synthetic drugs, including bath salts, sometimes try to avoid the law by labeling products as Not for Human Consumption. Many states have passed laws to stop this practice. TAKE ACTION If someone you know has a bad reaction to what you think is a synthetic drug, call your local poison control center at 1-800-222-1222. If they stop breathing, collapse, or have a seizure, call 911 immediately. MORE INFO: For additional facts about drugs and health, visit scholastic.com /headsup and teens.drugabuse.gov. From Scholastic and the scientists of the National Institute on Drug Abuse, National Institutes of Health, U.S. Department of Health and Human Services

Supplement to Scholastic magazines. Scholastic and associated logos are trademarks and/or registered trademarks of Scholastic Inc. All rights reserved. NIDA 17 18; Insert 2 Upf, Sco, Cho, JS, SW. HEADS UP REAL NEWS ABOUT DRUGS AND YOUR BODY TEACHER S GUIDE Subjects Science Literacy English Language Arts Health/Life Skills Common Core State Standards RST.6-8.1 / RST.9-10.1 Cite specific textual evidence to support analysis of science and technical texts W.6-8.1 / W.9-10.1 Write arguments to support claims, using valid reasoning and relevant and sufficient evidence Next Generation Science Standards MS-PS1.A / HS-PS1.A Structure and Properties of Matter MS-LS3.B / HS-LS3.B Information Processing National Science Education Standards Properties and Changes of Properties in Matter/ Structure and Properties of Matter Personal Health National Council for the Social Studies 4. Individual Development and Identity 8. Science, Technology, and Society Not Fit for Human Consumption In recent years, there has been a rise in the number of health emergencies and overdoses related to drugs that are made illegally in laboratories. Synthetic drugs are created in these labs to mimic the effects of other, more commonly known substances, such as marijuana and prescription pain medications. But these unregulated drugs can be even more dangerous than their counterparts. In Not Fit for Human Consumption students will learn what synthetic drugs are and why they are dangerous. You can help students stay safe from synthetic drugs by sharing the article and paired worksheet (see reverse side), and teaching the lesson below. Critical-Thinking Questions 1) Why might a synthetic drug pose more health risks than its more familiar counterpart? Use evidence from the text to support your answer. (Answers may include: Synthetic drugs made in illegal laboratories may have different chemicals that make them more powerful. There is no way to know what chemicals the drugs contain and in what amounts. The chemicals in synthetic drugs can have different or stronger effects on the body. For example, synthetic cannabinoids have a stronger effect on the brain than THC, the main active ingredient in marijuana.) 2) Officials try to reduce the misuse of drugs by regulating their use and making them illegal. Why is this approach difficult with synthetic drugs? (Answers may include that the makers of synthetic drugs can add misleading labels to products, such as Not Fit for Human Consumption. ) 3) Why is it important to use only prescription medications that have been prescribed by a doctor and bought directly from a pharmacy? (Answers may include that medications such as pills bought on the street or online may be counterfeit. The effects of these medications can be unpredictable and may be deadly because they may contain hidden chemicals such as fentanyl.) Writing Prompts Grades 6 8: Explain what a synthetic drug is and how it is different from the drug it is designed to mimic. Grades 9 10: The article states that the effect of synthetic drugs is unpredictable. Use evidence from the text to support this statement. Grades 11 12: The U.S. is currently experiencing an overdose crisis related to opioids. How might synthetic drugs play a role in this crisis? Use evidence from the text to support your answer. Student Worksheet The worksheet on the reverse side includes fill-in-the-blank questions to reinforce comprehension of the article. It also includes a prompt for students to use the information they have learned to create a poster warning teens about the dangers of synthetic drugs. Answers Part 1: 1. laboratories; designed. 2. powerful. 3. Spice; K2; cannabinoids. 4. THC. 5. bath salts. 6. Counterfeit; fentanyl. 7. misleading. 8. addiction; overdose. Part 2: Each student poster, flyer, or meme should include elements that grab the reader s attention, such as startling facts or statistics or eye-catching visuals. It should include facts about why synthetic drugs are dangerous and advice about how to stay safe. Tiered Vocabulary Tools Visit scholastic.com/headsup/not_fit _for_human_consumption for a tiered vocabulary list to support this article. Paired Reading Drug Facts: Spice (https://teens.drugabuse.gov/drug-facts/spice) Writing Prompt: Explain the dangers of the synthetic drug Spice. Include why it may affect a person s body differently than marijuana. Use text evidence from Not Fit for Human Consumption and Drug Facts: Spice to support your answer. Additional Teaching Resources headsup.scholastic.com/teachers teens.drugabuse.gov

SCHOLASTIC.COM/HEADSUP HOW MUCH DO YOU KNOW ABOUT SYNTHETIC DRUGS? Part 1: Use the information from the article Not Fit for Human Consumption to answer the questions below about synthetic drugs and their effects. THC cannabinoids laboratories stimulant counterfeit designed K2 addiction misleading overdose cathinones powerful Spice synthetic natural bath salts fentanyl reduce 1. Synthetic drugs made in illegal can contain chemicals to act like other drugs. 2. One reason synthetic drugs are dangerous is they often have added chemicals that make them more. 3. and are drugs made of dried plant leaves sprayed with synthetic that can cause dangerous health problems, including heart attacks. 4. is the main active ingredient in marijuana. 5. Like the stimulant drugs they mimic, contain chemicals called cathinones, which can cause hallucinations, paranoia, and a dangerous increase in heart rate. 6. prescription medications sold on the street have been found to contain hidden amounts of the powerful synthetic opioid. 7. The producers of illegal synthetic drugs sometimes package the drugs with labels that are. 8. Both legitimate and illegal synthetic opioids can pose a high risk for and. Part 2: Use the information in the article and your own Internet research from reliable sources to create a poster, flyer, or meme warning other teens about the dangers of synthetic drugs. Points to consider: What images can you use to grab the reader s attention? What important facts do you think people need to know? What advice would you give teens about synthetic drugs? FROM SCHOLASTIC AND THE SCIENTISTS OF THE NATIONAL INSTITUTE ON DRUG ABUSE, NATIONAL INSTITUTES OF HEALTH, U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

VOCABULARY LIST GRADES 6 12 Dear Teacher, The vocabulary list on the following pages is drawn from the Not Fit for Human Consumption student article and How Much Do You Know About Synthetic Drugs? worksheet. This vocabulary can be previewed with students prior to reading or reinforced with students afterward. Encourage students to incorporate these words into their writing and discussion of the article and worksheet. Supplement for Not Fit for Human Consumption Student Article: scholastic.com/ headsup/not_fit_for_human_ consumption Teacher s Guide (includes work sheet): scholastic.com/headsup/teachers/ not_fit_for_human_consumption The vocabulary list integrates vocabulary words that would be used across several content areas, such as consumption, legitimate, and misleading, and domain-specific words, such as opioid, stimulant, and synthetic. Some suggestions for students to help their understanding include: organizing concept maps that include word parts, synonyms, antonyms, and examples; composing memory aids that explain the words or use them in a meaningful context; employing the words to create newspaper articles, stories, or poems. Sources: Unless otherwise noted, definitions are sourced or adapted from: Merriam-Webster Collegiate Dictionary and Scholastic Children s Dictionary. Continue to vocabulary sheet on next page.

VOCABULARY LIST FROM NOT FIT FOR HUMAN CONSUMPTION addiction (noun): a brain disorder or illness associated with compulsive (uncontrollable) behavior, such as drug use, despite negative consequences addictive (adjective): something, such as a drug, that causes changes to the brain that result in compulsive (uncontrollable) behavior despite negative consequences amphetamine (noun): a type of stimulant drug that increases certain brain activity anxiety (noun): a feeling of fear or worry bath salts (noun): a name given to a drug made from synthetic cathinones cannabinoid (noun): a chemical that is found naturally in hemp plants and causes changes in the brain and behavior cathinone (noun): a chemical found naturally in the leaves of the khat plant that increases certain activity in the brain and nervous system chemical (noun): a substance, such as an element or a mix of elements (compound), that is made by a chemical process consumption (noun): the act of eating, drinking, or using up something counterfeit (adjective): made in imitation of something else with the goal of deceiving or cheating craving (noun): an intense or abnormal desire for something dependent (adjective): having a need for a drug because of repeated use so that physical withdrawal symptoms are experienced if the drug is removed designed (adjective): created to have a certain purpose or function disguised (adjective): having the true state or character concealed or hidden distributor (noun): a company that buys products from one company and arranges for other companies or individuals to sell them dose (noun): the measured amount of a chemical such as a drug to be taken at one time ensure (verb): to make sure fentanyl (noun): an opioid drug made in laboratories that is much stronger (50 to 100 times) than other legal opioids. It is prescribed only to treat very severe pain. hallucination (noun): the perception of objects that are not real hydrocodone (noun): an opioid drug that is used as a painkiller and prescribed by doctors for moderate to severe pain illegal (adjective): against the law ingredient (noun): something that is a part of a combination or mixture K2 (noun): the name sometimes given to a drug made from dried plant leaves sprayed with synthetic cannabinoid chemicals that are similar to THC laboratory (noun): a place where scientific experiments are done or products such as drugs are made legal (adjective): allowed by the law legitimate (adjective): being exactly as described, not false marijuana (noun): dried leaves and flowers of the hemp plant which can be used as a drug MDMA (Ecstasy or Molly) (noun): an illegal stimulant drug that gives feelings of pleasure and excitement medication (noun): a chemical or substance that is used to treat a disease or medical condition misleading (adjective): giving the wrong idea or inaccurate information about something, usually on purpose misuse (verb): to use something in a way that is unintended or harmful, such as misuse of a prescription drug Continued on next page.

VOCABULARY LIST FROM NOT FIT FOR HUMAN CONSUMPTION morphine (noun): an opioid drug that is used as a painkiller and is prescribed by doctors for moderate to severe pain natural (adjective): existing in or produced by nature Norco (noun): a brand-name version of the drug hydrocodone official (adjective): of or having to do with someone in a position of authority opioid (noun): one of a group of drugs that produce relaxation, pleasure, and pain relief. Opioids can be addictive and potentially deadly due to overdoses. overdose (noun): a lethal or toxic amount of a drug; (verb): to take a lethal or toxic amount of a drug paranoia (noun): a tendency for extreme and unreasonable distrust or suspicion of other people pose (verb): to present or create potent (adjective): having a powerful effect potentially (adverb): possibly, but not yet actual prescribe (verb): to write or give medical instructions, such as regarding the use of certain medications prescription drug (noun): a medication that must be ordered by a doctor before it can be dispensed Spice (noun): the name sometimes given to a drug made from dried plant leaves sprayed with synthetic cannabinoid chemicals that are similar to THC stimulant (noun): a drug that causes a temporary increase in activity in parts of the brain and body substance (noun): a material with a specific chemical makeup surge (verb): to rise suddenly to an excessive or abnormal amount synthetic (adjective): produced by a chemical process THC (noun): a type of natural cannabinoid chemical that is the main active ingredient in marijuana treat (verb): to care for or deal with medically; to act upon something with an agent such as a chemical to improve or alter undergo (verb): to go through or experience unpredictable (adjective): not able to be known in advance unregulated (adjective): not controlled by rules or methods that are used to make sure certain standards of safety or quality are met version (noun): a different form or type of something regulate (verb): to bring under control of the law or rules regulation (noun): a rule that deals with details and procedures, such as those that are used to make sure something is safe respond (verb): to react to something retailer (noun): of or having to do with the sale of goods directly to customers risk (noun): the possibility of loss or injury; danger seizure (noun): a sudden attack caused by abnormal activity in the brain that causes convulsions or loss of consciousness severe (adjective): of a great degree